PT2997015T - Compostos fenoxietil-di-hidro-1h-isoquinolina - Google Patents
Compostos fenoxietil-di-hidro-1h-isoquinolinaInfo
- Publication number
- PT2997015T PT2997015T PT147276927T PT14727692T PT2997015T PT 2997015 T PT2997015 T PT 2997015T PT 147276927 T PT147276927 T PT 147276927T PT 14727692 T PT14727692 T PT 14727692T PT 2997015 T PT2997015 T PT 2997015T
- Authority
- PT
- Portugal
- Prior art keywords
- isoquinoline compounds
- phenoxyethyl
- dihydro
- phenoxyethyl dihydro
- isoquinoline
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361824436P | 2013-05-17 | 2013-05-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2997015T true PT2997015T (pt) | 2017-04-24 |
Family
ID=50877688
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT147276927T PT2997015T (pt) | 2013-05-17 | 2014-05-09 | Compostos fenoxietil-di-hidro-1h-isoquinolina |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US9371289B2 (pt) |
| EP (1) | EP2997015B1 (pt) |
| JP (1) | JP6148400B2 (pt) |
| KR (1) | KR101798315B1 (pt) |
| CN (1) | CN105209438B (pt) |
| BR (1) | BR112015026967B1 (pt) |
| CA (1) | CA2908400C (pt) |
| EA (1) | EA027306B1 (pt) |
| ES (1) | ES2626976T3 (pt) |
| HU (1) | HUE033574T2 (pt) |
| MX (1) | MX2015015841A (pt) |
| PL (1) | PL2997015T3 (pt) |
| PT (1) | PT2997015T (pt) |
| SA (1) | SA515370035B1 (pt) |
| TW (1) | TWI636046B (pt) |
| WO (1) | WO2014186218A1 (pt) |
| ZA (1) | ZA201507566B (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105793242B (zh) * | 2013-12-17 | 2018-02-16 | 伊莱利利公司 | 苯氧基乙基环状胺衍生物及其作为ep4受体调节剂的活性 |
| CR20180323A (es) | 2015-11-20 | 2018-08-06 | Idorsia Pharmaceuticals Ltd | Derivados de indol n-sustituídos como moduladores de los receptores de pge2 |
| TW201900179A (zh) | 2017-05-18 | 2019-01-01 | 瑞士商愛杜西亞製藥有限公司 | 作為pge2受體調節劑之苯并呋喃及苯并噻吩衍生物 |
| TW201900178A (zh) | 2017-05-18 | 2019-01-01 | 瑞士商愛杜西亞製藥有限公司 | 作為pge2受體調節劑之嘧啶衍生物 |
| UA124748C2 (uk) | 2017-05-18 | 2021-11-10 | Ідорсія Фармасьютікалз Лтд | N-заміщені індольні похідні |
| CA3063788A1 (en) | 2017-05-18 | 2018-11-22 | Idorsia Pharmaceuticals Ltd | Pyrimidine derivatives |
| MA49126B1 (fr) | 2017-05-18 | 2021-10-29 | Idorsia Pharmaceuticals Ltd | Dérivés de phényle utilisés en tant que modulateurs des récepteurs des pge2 |
| KR20230107228A (ko) | 2020-11-13 | 2023-07-14 | 오노 야꾸힝 고교 가부시키가이샤 | Ep4 길항약과 면역 체크포인트 저해 물질의 병용에 의한 암 치료 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2500157C2 (de) | 1975-01-03 | 1983-09-15 | Hoechst Ag, 6230 Frankfurt | N-Acyl-4-(2-aminoäthyl)-benzoesäuren, deren Salze und Ester, Verfahren zu deren Herstellung und deren Verwendung |
| IT1270615B (it) | 1994-07-14 | 1997-05-07 | Smithkline Beecham Farma | Uso di derivati di chinolina |
| US6649606B1 (en) * | 2001-11-09 | 2003-11-18 | Bristol-Myers Squibb Co. | Tetrahydroisoquinoline analogs as modulators of chemokine receptor activity |
| JP4663233B2 (ja) | 2001-11-09 | 2011-04-06 | エンゾン，インコーポレーテッド | ベンジル脱離系を利用する高分子チオール結合プロドラッグ |
| EP1558253A4 (en) * | 2002-10-30 | 2007-07-25 | Merck & Co Inc | PIPERIDINYL ALPHA AMINOAMIDE MODULATORS DERCHEMOKIN RECEPTOR ACTIVITY |
| CA2531796A1 (en) * | 2003-08-08 | 2005-02-17 | Transtech Pharma, Inc. | Aryl and heteroaryl compounds, compositions, and methods of use |
| BRPI0414130B8 (pt) | 2003-09-03 | 2021-05-25 | Askat Inc | compostos de fenilamida ou piridilamida, seu uso e composições farmacêuticas que os compreendem. |
| CA2565813C (en) | 2004-05-04 | 2010-10-26 | Pfizer Inc. | Substituted methyl aryl or heteroaryl amide compounds |
| JP4054369B2 (ja) | 2004-05-04 | 2008-02-27 | ファイザー株式会社 | オルト置換アリールまたはヘテロアリールアミド化合物 |
| US8697716B2 (en) | 2006-04-20 | 2014-04-15 | Janssen Pharmaceutica Nv | Method of inhibiting C-KIT kinase |
| WO2007121578A1 (en) | 2006-04-24 | 2007-11-01 | Merck Frosst Canada Ltd. | Indole amide derivatives as ep4 receptor antagonists |
| AU2007260529B2 (en) | 2006-06-12 | 2012-04-19 | Merck Canada Inc. | Indoline amide derivatives as EP4 receptor ligands |
| SI2565191T1 (sl) * | 2008-05-14 | 2014-12-31 | Astellas Pharma Inc. | Derivati 4-(indol-7-ilkarbonilaminometil)cikloheksan karboksilne kisline kot EP4 receptorski antagonisti, uporabni za zdravljenje kronične ledvične odpovedi ali diabetične nefropatije |
| CA2733247C (en) | 2008-08-14 | 2018-04-03 | Beta Pharma Canada Inc. | Heterocyclic amide derivatives as ep4 receptor antagonists |
| MX341482B (es) | 2010-02-22 | 2016-08-22 | Raqualia Pharma Inc | Antagonistas del receptor ep4 y su uso en el tratamiento de enfermedades mediadas por la il-23. |
| ES2559513T3 (es) * | 2011-07-04 | 2016-02-12 | Rottapharm Biotech S.R.L. | Derivados de amina cíclica como antagonistas del receptor EP4 |
| WO2013004291A1 (en) | 2011-07-04 | 2013-01-10 | Rottapharm S.P.A. | Cyclic amine derivatives as ep4 receptor agonists |
| EP2572746A1 (en) * | 2011-09-23 | 2013-03-27 | Sanofi-Aventis Deutschland GmbH | Needle safety device |
| TWI572597B (zh) | 2012-06-29 | 2017-03-01 | 美國禮來大藥廠 | 二甲基－苯甲酸化合物 |
| JO3296B1 (ar) | 2012-06-29 | 2018-09-16 | Lilly Co Eli | مركبات فينوكسي إيثيل بيبريدين |
-
2014
- 2014-05-02 TW TW103115871A patent/TWI636046B/zh active
- 2014-05-09 PL PL14727692T patent/PL2997015T3/pl unknown
- 2014-05-09 EA EA201591915A patent/EA027306B1/ru not_active IP Right Cessation
- 2014-05-09 EP EP14727692.7A patent/EP2997015B1/en active Active
- 2014-05-09 PT PT147276927T patent/PT2997015T/pt unknown
- 2014-05-09 HU HUE14727692A patent/HUE033574T2/hu unknown
- 2014-05-09 JP JP2016513099A patent/JP6148400B2/ja active Active
- 2014-05-09 ES ES14727692.7T patent/ES2626976T3/es active Active
- 2014-05-09 CN CN201480028163.9A patent/CN105209438B/zh active Active
- 2014-05-09 WO PCT/US2014/037416 patent/WO2014186218A1/en active Application Filing
- 2014-05-09 BR BR112015026967-2A patent/BR112015026967B1/pt active IP Right Grant
- 2014-05-09 CA CA2908400A patent/CA2908400C/en active Active
- 2014-05-09 KR KR1020157032468A patent/KR101798315B1/ko active IP Right Grant
- 2014-05-09 US US14/888,497 patent/US9371289B2/en active Active
- 2014-05-09 MX MX2015015841A patent/MX2015015841A/es active IP Right Grant
-
2015
- 2015-10-12 ZA ZA2015/07566A patent/ZA201507566B/en unknown
- 2015-10-22 SA SA515370035A patent/SA515370035B1/ar unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2908400C (en) | 2017-04-11 |
| TWI636046B (zh) | 2018-09-21 |
| ZA201507566B (en) | 2017-06-28 |
| TW201534588A (zh) | 2015-09-16 |
| EA027306B1 (ru) | 2017-07-31 |
| HUE033574T2 (hu) | 2017-12-28 |
| AU2014265762A1 (en) | 2015-10-15 |
| CA2908400A1 (en) | 2014-11-20 |
| WO2014186218A1 (en) | 2014-11-20 |
| US9371289B2 (en) | 2016-06-21 |
| SA515370035B1 (ar) | 2018-01-04 |
| EP2997015A1 (en) | 2016-03-23 |
| BR112015026967A2 (pt) | 2017-07-25 |
| CN105209438A (zh) | 2015-12-30 |
| MX2015015841A (es) | 2016-03-04 |
| PL2997015T3 (pl) | 2017-09-29 |
| EA201591915A1 (ru) | 2016-04-29 |
| BR112015026967B1 (pt) | 2023-01-10 |
| KR101798315B1 (ko) | 2017-11-15 |
| JP6148400B2 (ja) | 2017-06-14 |
| EP2997015B1 (en) | 2017-04-05 |
| KR20150140831A (ko) | 2015-12-16 |
| JP2016519140A (ja) | 2016-06-30 |
| BR112015026967A8 (pt) | 2018-01-30 |
| CN105209438B (zh) | 2017-04-12 |
| ES2626976T3 (es) | 2017-07-26 |
| US20160052889A1 (en) | 2016-02-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1212694A1 (zh) | 四氫吡咯並三嗪類化合物 | |
| GB201309085D0 (en) | Compounds | |
| GB201302927D0 (en) | Compounds | |
| GB201310542D0 (en) | Compounds | |
| GB201311951D0 (en) | Compounds | |
| GB201309508D0 (en) | Compounds | |
| ZA201507566B (en) | Phenoxyethyl dihydro-1h-isoquinoline compounds | |
| GB201320636D0 (en) | Compounds | |
| AP3850A (en) | Azetidinyloxyphenylpyrrolidine compounds | |
| GB201319363D0 (en) | Compounds | |
| GB201317619D0 (en) | Compounds | |
| GB201312901D0 (en) | Compounds | |
| GB201311953D0 (en) | Compounds | |
| EP3010923A4 (en) | PYRROLOCHINAZOLINVERBINDUNGEN | |
| EP2948457A4 (en) | COMPOUNDS | |
| GB201318461D0 (en) | Compounds | |
| GB201316014D0 (en) | Compounds | |
| GB201310460D0 (en) | Compounds | |
| GB201306794D0 (en) | Compounds | |
| GB201322855D0 (en) | Compounds | |
| GB201322028D0 (en) | Compounds | |
| GB201321554D0 (en) | Compounds | |
| GB201321553D0 (en) | Compounds | |
| GB201321283D0 (en) | Compounds | |
| GB201318323D0 (en) | Compounds |