PT2882723T - Processo para o fabrico de isavuconazol ou ravuconazol - Google Patents

Processo para o fabrico de isavuconazol ou ravuconazol

Info

Publication number
PT2882723T
PT2882723T PT137479994T PT13747999T PT2882723T PT 2882723 T PT2882723 T PT 2882723T PT 137479994 T PT137479994 T PT 137479994T PT 13747999 T PT13747999 T PT 13747999T PT 2882723 T PT2882723 T PT 2882723T
Authority
PT
Portugal
Prior art keywords
isavuconazole
ravuconazole
manufacture
Prior art date
Application number
PT137479994T
Other languages
English (en)
Inventor
Van Summeren Ruben
Vaessen Harrie
Mink Daniel
Waser Mario
Original Assignee
Basilea Pharmaceutica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basilea Pharmaceutica Ag filed Critical Basilea Pharmaceutica Ag
Publication of PT2882723T publication Critical patent/PT2882723T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
PT137479994T 2012-08-07 2013-07-31 Processo para o fabrico de isavuconazol ou ravuconazol PT2882723T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP12179540 2012-08-07

Publications (1)

Publication Number Publication Date
PT2882723T true PT2882723T (pt) 2017-02-23

Family

ID=48979725

Family Applications (1)

Application Number Title Priority Date Filing Date
PT137479994T PT2882723T (pt) 2012-08-07 2013-07-31 Processo para o fabrico de isavuconazol ou ravuconazol

Country Status (15)

Country Link
US (2) US9783508B2 (pt)
EP (1) EP2882723B1 (pt)
JP (1) JP6334529B2 (pt)
KR (1) KR102129150B1 (pt)
CN (1) CN104507917B (pt)
BR (1) BR112015002526B1 (pt)
CA (1) CA2878361C (pt)
ES (1) ES2616412T3 (pt)
HR (1) HRP20170171T1 (pt)
HU (1) HUE031679T2 (pt)
MX (1) MX360783B (pt)
PL (1) PL2882723T3 (pt)
PT (1) PT2882723T (pt)
SI (1) SI2882723T1 (pt)
WO (1) WO2014023623A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105801500B (zh) * 2014-12-31 2018-08-24 四川科伦药物研究院有限公司 拆分艾沙康唑中间化合物消旋体的方法
CN106317044A (zh) * 2015-06-30 2017-01-11 刘玫君 一种制造艾沙康唑或雷夫康唑的方法
CN104961695A (zh) * 2015-07-27 2015-10-07 成都塞恩斯医药科技有限公司 一种艾沙康唑和雷夫康唑中间体的制备方法
CN106467534B (zh) * 2015-08-17 2019-10-11 江苏奥赛康药业有限公司 一种硫酸艾沙康唑鎓化合物及其药物组合物
CN105907832B (zh) * 2015-12-02 2019-07-12 成都师范学院 一种酶法拆分艾沙康唑中间体的方法
CN105777740B (zh) * 2016-02-24 2018-03-27 苏州金点生物科技有限公司 一种艾沙康唑的制备方法
CN117511890A (zh) * 2017-04-27 2024-02-06 科德克希思公司 酮还原酶多肽及多核苷酸
WO2021245590A1 (en) * 2020-06-04 2021-12-09 Metrochem Api Private Limited An improved process for the preparation of triazole derivatives
CN111574444A (zh) * 2020-07-07 2020-08-25 安徽贝克生物制药有限公司 一种贝达喹啉的制备方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8510195D0 (en) * 1985-04-22 1985-05-30 Ici Plc Heterocyclic compounds
US5134152A (en) 1989-12-07 1992-07-28 Sankyo Company, Limited Oxetane derivatives and their use as anti-fungal or fungicidal agents
JP2887523B2 (ja) * 1990-11-30 1999-04-26 富山化学工業株式会社 新規なトリアゾール誘導体およびその塩
GB9107055D0 (en) 1991-04-04 1991-05-22 Pfizer Ltd Triazole antifungal agents
JP4208269B2 (ja) * 1996-10-01 2009-01-14 東芝ソリューション株式会社 異種物混入検査方法及びそのシステム
WO1999002524A1 (fr) 1997-07-08 1999-01-21 Sankyo Company, Limited Composes antifongiques a base de triazole
WO1999045008A1 (en) 1998-03-06 1999-09-10 F. Hoffmann-La Roche Ag 3-[4-(4-cyanophenyl)thiazol-2-y)]-1-(1h-1,2,4-triazol-1-yl)-butan-2-ol derivatives having antifungal activity
WO2003002498A1 (en) * 2001-06-26 2003-01-09 Basilea Pharmaceutica Ag Intermediate halophenyl derivatives and their use in a process for preparing azole derivatives
JP5329969B2 (ja) 2005-12-01 2013-10-30 バジリア ファルマスーチカ アーゲー エポキシブタノール中間体の製造方法
GB0712972D0 (en) 2007-07-04 2007-08-15 Glaxosmithkline Consumer Healt Formulation
EP2171061B1 (en) 2007-07-04 2017-09-27 DPx Holdings B.V. Preparation of an esterase
BRPI0816814B1 (pt) 2007-09-12 2021-08-31 Kyorin Pharmaceutical Co. Ltd Composto, composição farmacêutica e uso de um composto
CA2727340A1 (en) * 2008-06-25 2009-12-30 Daiichi Sankyo Company, Limited Carboxylic acid compound
HUE031419T2 (en) * 2008-07-03 2017-07-28 Astellas Pharma Inc Triazole derivative or salt
CN102439142B (zh) 2009-04-24 2015-11-25 DPx控股有限公司 改进的猪肝酯酶
US8207352B2 (en) 2009-10-08 2012-06-26 Drug Process Licensing Associates LLC Process for the manufacture of enantiomerically pure antifungal azoles as ravuconazole and isavuconazole
WO2011145669A1 (ja) * 2010-05-19 2011-11-24 大日本住友製薬株式会社 アミド誘導体

Also Published As

Publication number Publication date
BR112015002526B1 (pt) 2022-09-06
MX2015000744A (es) 2015-04-14
SI2882723T1 (sl) 2017-04-26
JP2015527345A (ja) 2015-09-17
JP6334529B2 (ja) 2018-05-30
MX360783B (es) 2018-11-16
EP2882723A1 (en) 2015-06-17
HRP20170171T1 (hr) 2017-04-07
WO2014023623A1 (en) 2014-02-13
CN104507917A (zh) 2015-04-08
US20190077771A1 (en) 2019-03-14
HUE031679T2 (en) 2017-07-28
KR102129150B1 (ko) 2020-07-02
US10590092B2 (en) 2020-03-17
ES2616412T3 (es) 2017-06-13
US20150239852A1 (en) 2015-08-27
EP2882723B1 (en) 2016-11-16
CN104507917B (zh) 2017-10-17
CA2878361C (en) 2020-09-22
KR20150037875A (ko) 2015-04-08
CA2878361A1 (en) 2014-02-13
BR112015002526A2 (pt) 2018-06-12
PL2882723T3 (pl) 2017-05-31
US9783508B2 (en) 2017-10-10

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