PT2467401T - Anticorpos para a deteção de complexos de integrina em material ffpe - Google Patents
Anticorpos para a deteção de complexos de integrina em material ffpeInfo
- Publication number
- PT2467401T PT2467401T PT107495939T PT10749593T PT2467401T PT 2467401 T PT2467401 T PT 2467401T PT 107495939 T PT107495939 T PT 107495939T PT 10749593 T PT10749593 T PT 10749593T PT 2467401 T PT2467401 T PT 2467401T
- Authority
- PT
- Portugal
- Prior art keywords
- antibodies
- detection
- ffpe material
- integrin complexes
- integrin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70546—Integrin superfamily, e.g. VLAs, leuCAM, GPIIb/GPIIIa, LPAM
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09010666 | 2009-08-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2467401T true PT2467401T (pt) | 2017-04-26 |
Family
ID=42813245
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT107495939T PT2467401T (pt) | 2009-08-19 | 2010-07-15 | Anticorpos para a deteção de complexos de integrina em material ffpe |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US8420348B2 (pt) |
| EP (1) | EP2467401B1 (pt) |
| JP (1) | JP5734978B2 (pt) |
| KR (1) | KR101606236B1 (pt) |
| CN (1) | CN102597001B (pt) |
| AU (1) | AU2010285265B2 (pt) |
| BR (1) | BR112012003686B1 (pt) |
| CA (1) | CA2771441C (pt) |
| DK (1) | DK2467401T3 (pt) |
| EA (1) | EA032728B1 (pt) |
| ES (1) | ES2622487T3 (pt) |
| HK (1) | HK1173455A1 (pt) |
| IL (1) | IL218119A (pt) |
| MX (1) | MX2012001741A (pt) |
| PT (1) | PT2467401T (pt) |
| SG (1) | SG178348A1 (pt) |
| WO (1) | WO2011020529A2 (pt) |
| ZA (1) | ZA201201990B (pt) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2325648T3 (da) | 2008-08-05 | 2014-07-28 | Toray Industries | Fremgangsmåde til detektering af cancer |
| RU2498819C2 (ru) | 2008-08-05 | 2013-11-20 | Торэй Индастриз, Инк. | Фармацевтическая композиция для лечения и профилактики злокачественных опухолей |
| PL2532743T3 (pl) | 2010-02-04 | 2015-09-30 | Toray Industries | Kompozycja farmaceutyczna do leczenia i/lub zapobiegania raka |
| JP5742714B2 (ja) | 2010-02-04 | 2015-07-01 | 東レ株式会社 | 癌の治療及び／又は予防用医薬組成物 |
| ES2691738T3 (es) | 2010-02-04 | 2018-11-28 | Toray Industries, Inc. | Agente farmacéutico para el tratamiento y/o la prevención de cáncer |
| LT2672994T (lt) | 2011-02-11 | 2018-07-25 | Merck Patent Gmbh | Anti-alfa-v integrino antikūnas, skirtas prostatos vėžio gydymui |
| AU2012290957B2 (en) | 2011-08-04 | 2017-04-20 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prophylaxis of cancer |
| US9180188B2 (en) | 2011-08-04 | 2015-11-10 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prophylaxis of cancer |
| AU2012290955B2 (en) | 2011-08-04 | 2017-04-27 | Toray Industries, Inc. | Drug composition for cancer treatment and/or prevention |
| HUE039219T2 (hu) | 2011-08-04 | 2018-12-28 | Toray Industries | Gyógyászati készítmény rák kezelésére és/vagy megelõzésére |
| PT2740795T (pt) | 2011-08-04 | 2017-01-09 | Toray Industries | Composição de fármaco para o tratamento e/ou a prevenção de cancro |
| AU2012290949B2 (en) | 2011-08-04 | 2017-03-02 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prevention of pancreatic cancer |
| PT2741085T (pt) | 2011-08-04 | 2017-06-30 | Toray Industries | Método para a deteção de cancro prancreático |
| JP6093360B2 (ja) * | 2011-08-17 | 2017-03-08 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | インテグリンα−ｖβ−８と結合する抗体 |
| CA2865020C (en) | 2012-02-21 | 2021-01-26 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prevention of cancer |
| EP2818481B1 (en) | 2012-02-21 | 2019-08-07 | Toray Industries, Inc. | Pharmaceutical composition for treatment and/or prevention of cancer |
| JP6187255B2 (ja) | 2012-02-21 | 2017-08-30 | 東レ株式会社 | 癌の治療及び／又は予防用医薬組成物 |
| KR102005786B1 (ko) | 2012-02-21 | 2019-07-31 | 도레이 카부시키가이샤 | 암의 치료 및/또는 예방용 의약 조성물 |
| PT2832366T (pt) | 2012-03-30 | 2018-01-25 | Toray Industries | Composição farmacêutica para o tratamento e/ou a prevenção de cancro de vesícula biliar |
| BR112014023937A2 (pt) | 2012-03-30 | 2018-04-17 | Toray Industries | composição farmacêutica, agente farmacêutico de combinação e método de tratamento |
| CN104471403B (zh) | 2012-07-19 | 2017-03-01 | 东丽株式会社 | 癌的检测方法 |
| EP2876447B1 (en) | 2012-07-19 | 2019-11-20 | Toray Industries, Inc. | Method for detecting cancer |
| CN105637097A (zh) | 2013-08-05 | 2016-06-01 | 特韦斯特生物科学公司 | 从头合成的基因文库 |
| MX360671B (es) | 2013-08-09 | 2018-11-13 | Toray Industries | Composición farmacéutica para el tratamiento y/o prevención del cáncer. |
| CA2936907C (en) | 2014-02-14 | 2022-06-07 | Arkansas Children's Hospital Research Institute, Inc. | Acetaminophen protein adducts and methods of use thereof |
| US10626166B2 (en) * | 2014-08-22 | 2020-04-21 | Baxalta Incorporated | Detection of CHO-MIF contaminations |
| EP3009147A1 (en) | 2014-10-16 | 2016-04-20 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Method for treating resistant glioblastoma |
| JP6785239B2 (ja) | 2014-12-03 | 2020-11-18 | バイオベンチャーズ・リミテッド・ライアビリティ・カンパニーＢｉｏＶｅｎｔｕｒｅｓ， ＬＬＣ | 抗アセトアミノフェン抗体及びアセトアミノフェンタンパク質付加物 |
| US10669304B2 (en) | 2015-02-04 | 2020-06-02 | Twist Bioscience Corporation | Methods and devices for de novo oligonucleic acid assembly |
| US9981239B2 (en) | 2015-04-21 | 2018-05-29 | Twist Bioscience Corporation | Devices and methods for oligonucleic acid library synthesis |
| EP3350314A4 (en) | 2015-09-18 | 2019-02-06 | Twist Bioscience Corporation | BANKS OF OLIGONUCLEIC ACID VARIANTS AND SYNTHESIS THEREOF |
| KR20180058772A (ko) | 2015-09-22 | 2018-06-01 | 트위스트 바이오사이언스 코포레이션 | 핵산 합성을 위한 가요성 기판 |
| WO2017182834A1 (en) | 2016-04-19 | 2017-10-26 | INSERM (Institut National de la Santé et de la Recherche Médicale) | New method for treating resistant glioblastoma |
| WO2018057526A2 (en) | 2016-09-21 | 2018-03-29 | Twist Bioscience Corporation | Nucleic acid based data storage |
| CN118116478A (zh) | 2017-02-22 | 2024-05-31 | 特韦斯特生物科学公司 | 基于核酸的数据存储 |
| KR20240013290A (ko) | 2017-06-12 | 2024-01-30 | 트위스트 바이오사이언스 코포레이션 | 심리스 핵산 어셈블리를 위한 방법 |
| WO2018231864A1 (en) | 2017-06-12 | 2018-12-20 | Twist Bioscience Corporation | Methods for seamless nucleic acid assembly |
| KR20200047706A (ko) | 2017-09-11 | 2020-05-07 | 트위스트 바이오사이언스 코포레이션 | Gpcr 결합 단백질 및 이의 합성 방법 |
| EP3697529B1 (en) | 2017-10-20 | 2023-05-24 | Twist Bioscience Corporation | Heated nanowells for polynucleotide synthesis |
| US11820823B2 (en) * | 2017-10-27 | 2023-11-21 | Kite Pharma, Inc. | T cell receptor antigen binding molecules and methods of use thereof |
| CA3100739A1 (en) | 2018-05-18 | 2019-11-21 | Twist Bioscience Corporation | Polynucleotides, reagents, and methods for nucleic acid hybridization |
| JP2022508015A (ja) * | 2018-09-07 | 2022-01-19 | ファイザー・インク | 抗αｖβ８抗体、組成物及びその使用 |
| US20220056155A1 (en) * | 2018-12-21 | 2022-02-24 | Board Of Regents, The University Of Texas System | Phosphorylated dicer antibody and methods of use thereof |
| US20220091135A1 (en) * | 2019-01-04 | 2022-03-24 | Kyoto University | Test method for ulcerative colitis and primary sclerosing cholangitis |
| CA3131691A1 (en) | 2019-02-26 | 2020-09-03 | Twist Bioscience Corporation | Variant nucleic acid libraries for antibody optimization |
| AU2020298294A1 (en) | 2019-06-21 | 2022-02-17 | Twist Bioscience Corporation | Barcode-based nucleic acid sequence assembly |
| US20220356238A1 (en) * | 2019-07-02 | 2022-11-10 | Astute Medical, Inc. | Antibodies and assays for ccl14 |
| CN114867746A (zh) * | 2019-08-09 | 2022-08-05 | 小利兰·斯坦福大学董事会 | 抗骨桥蛋白的治疗性抗体 |
| CA3155630A1 (en) * | 2019-09-23 | 2021-04-01 | Twist Bioscience Corporation | Variant nucleic acid libraries for single domain antibodies |
| BR112022009570A2 (pt) * | 2019-12-05 | 2022-08-02 | Seagen Inc | Anticorpo anti-¿v¿6 isolado ou fragmento de ligação ao antígeno, conjugado anticorpo-fármaco, ácido nucleico, vetor, célula hospedeira, métodos para produção de um anticorpo anti-¿v¿6 ou fragmento de ligação ao antígeno, para produção de um conjugado anticorpo anti-¿v¿6-fármaco e para tratamento de câncer em um indivíduo, e, composição farmacêutica |
| CN114907468B (zh) * | 2022-06-10 | 2023-05-23 | 东莞理工学院 | 一种仿刺参整合素多克隆抗体、抗原蛋白及其制备方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1989005155A1 (en) * | 1987-11-19 | 1989-06-15 | Scripps Clinic And Research Foundation | Monoclonal antibody against the rgd-directed adhesion receptor of endothelial cells |
| UA58482C2 (uk) * | 1994-06-08 | 2003-08-15 | Бьорінгер Інгельхайм Інтернаціональ Гмбх | Моноклональне антитіло vff-18 проти сd44v6 і його фрагменти |
| WO1997010796A2 (en) * | 1995-09-01 | 1997-03-27 | Ramot-University Authority For Applied Research And Industrial Development Ltd. | MANIPULATION AND DETECTION OF PROTEIN PHOSPHATASE 2C - PP2Cα - EXPRESSION IN TUMOR CELLS FOR CANCER THERAPY, PREVENTION AND DETECTION |
| EP1082339A2 (de) | 1998-06-02 | 2001-03-14 | Affina Immuntechnik GmbH | Rational designte peptide, ihre herstellung und ihre verwendung |
| US7163681B2 (en) * | 2000-08-07 | 2007-01-16 | Centocor, Inc. | Anti-integrin antibodies, compositions, methods and uses |
| US7205382B2 (en) | 2000-11-08 | 2007-04-17 | Fresenius Medical Care Affina Gmbh | Peptides, the production and use thereof for binding immunoglobulins |
| AU2002258518A1 (en) * | 2001-03-14 | 2002-09-24 | Millennium Pharmaceuticals, Inc. | Nucleic acid molecules and proteins for the identification, assessment, prevention, and therapy of ovarian cancer |
| JP2005533001A (ja) | 2002-03-04 | 2005-11-04 | メディミューン，インコーポレーテッド | インテグリンαｖβ３アンタゴニストを他の物質と併用投与する癌の予防または治療方法 |
| CA2478833C (en) * | 2002-03-13 | 2015-11-10 | Biogen, Inc. | Anti-.alpha.v.beta.6 antibodies |
| AU2003230929A1 (en) * | 2002-04-12 | 2003-10-27 | Raven Biotechnologies, Inc. | Antibodies that bind to integrin alpha-v-beta-6 and methods of use thereof |
| AU2003256584A1 (en) * | 2002-07-17 | 2004-02-02 | The Center For Blood Research, Inc. | Modified proteins stabilized in a desired conformation and methods for producing same |
| CN1444043A (zh) * | 2002-12-25 | 2003-09-24 | 帕弗瑞生物技术(北京)有限公司 | 一种个体化特异性免疫细胞功能测定方法 |
| SE0301087D0 (sv) * | 2003-04-14 | 2003-04-14 | Cartela Ab | New monoclonal antibody |
| US7429487B2 (en) | 2005-07-05 | 2008-09-30 | Epitomics, Inc. | Fusion partner for production of monoclonal rabbit antibodies |
| JP2009521909A (ja) * | 2005-12-30 | 2009-06-11 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | ＩＬ−６とＩＬ−６Ｒαの複合体のｇｐ１３０への結合を阻害する抗ＩＬ−６抗体 |
| JP5341889B2 (ja) * | 2007-07-17 | 2013-11-13 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 操作された抗αＶインテグリンハイブリッド抗体 |
-
2010
- 2010-07-15 JP JP2012525056A patent/JP5734978B2/ja active Active
- 2010-07-15 BR BR112012003686-6A patent/BR112012003686B1/pt active IP Right Grant
- 2010-07-15 US US13/390,791 patent/US8420348B2/en active Active
- 2010-07-15 MX MX2012001741A patent/MX2012001741A/es active IP Right Grant
- 2010-07-15 WO PCT/EP2010/004313 patent/WO2011020529A2/en active Application Filing
- 2010-07-15 ES ES10749593.9T patent/ES2622487T3/es active Active
- 2010-07-15 SG SG2012009254A patent/SG178348A1/en unknown
- 2010-07-15 CA CA2771441A patent/CA2771441C/en active Active
- 2010-07-15 DK DK10749593.9T patent/DK2467401T3/en active
- 2010-07-15 PT PT107495939T patent/PT2467401T/pt unknown
- 2010-07-15 CN CN201080036609.4A patent/CN102597001B/zh active Active
- 2010-07-15 EP EP10749593.9A patent/EP2467401B1/en active Active
- 2010-07-15 EA EA201200281A patent/EA032728B1/ru not_active IP Right Cessation
- 2010-07-15 KR KR1020127006938A patent/KR101606236B1/ko active IP Right Grant
- 2010-07-15 AU AU2010285265A patent/AU2010285265B2/en active Active
-
2012
- 2012-02-14 IL IL218119A patent/IL218119A/en active IP Right Grant
- 2012-03-16 ZA ZA2012/01990A patent/ZA201201990B/en unknown
-
2013
- 2013-01-15 HK HK13100599.0A patent/HK1173455A1/xx unknown
- 2013-03-15 US US13/838,405 patent/US8993261B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2011020529A2 (en) | 2011-02-24 |
| JP5734978B2 (ja) | 2015-06-17 |
| US20130203079A1 (en) | 2013-08-08 |
| AU2010285265A2 (en) | 2012-06-07 |
| BR112012003686B1 (pt) | 2021-09-21 |
| US20120171699A1 (en) | 2012-07-05 |
| JP2013502205A (ja) | 2013-01-24 |
| IL218119A0 (en) | 2012-04-30 |
| EA201200281A1 (ru) | 2012-09-28 |
| HK1173455A1 (en) | 2013-05-16 |
| CN102597001A (zh) | 2012-07-18 |
| SG178348A1 (en) | 2012-03-29 |
| WO2011020529A3 (en) | 2011-06-16 |
| KR20120059556A (ko) | 2012-06-08 |
| BR112012003686A2 (pt) | 2016-03-29 |
| AU2010285265B2 (en) | 2015-05-21 |
| CA2771441C (en) | 2016-10-11 |
| EP2467401A2 (en) | 2012-06-27 |
| ES2622487T3 (es) | 2017-07-06 |
| CA2771441A1 (en) | 2011-02-24 |
| EA032728B1 (ru) | 2019-07-31 |
| US8420348B2 (en) | 2013-04-16 |
| WO2011020529A8 (en) | 2011-04-21 |
| US8993261B2 (en) | 2015-03-31 |
| ZA201201990B (en) | 2012-11-28 |
| DK2467401T3 (en) | 2017-03-20 |
| CN102597001B (zh) | 2014-07-30 |
| MX2012001741A (es) | 2012-03-21 |
| IL218119A (en) | 2015-08-31 |
| AU2010285265A1 (en) | 2012-04-05 |
| EP2467401B1 (en) | 2017-01-18 |
| KR101606236B1 (ko) | 2016-03-24 |
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