PT2432804E - Anticorpos ou seus fragmentos direcionados contra um epítopo de staphylococcus aureus de isaa ou isab - Google Patents

Anticorpos ou seus fragmentos direcionados contra um epítopo de staphylococcus aureus de isaa ou isab Download PDF

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Publication number
PT2432804E
PT2432804E PT107204166T PT10720416T PT2432804E PT 2432804 E PT2432804 E PT 2432804E PT 107204166 T PT107204166 T PT 107204166T PT 10720416 T PT10720416 T PT 10720416T PT 2432804 E PT2432804 E PT 2432804E
Authority
PT
Portugal
Prior art keywords
antibodies
fragments
ala
ser
staphylococcus aureus
Prior art date
Application number
PT107204166T
Other languages
English (en)
Portuguese (pt)
Inventor
Knut Ohlsen
Udo Lorenz
Original Assignee
Julius Maximilians Universität Würzburg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Julius Maximilians Universität Würzburg filed Critical Julius Maximilians Universität Würzburg
Publication of PT2432804E publication Critical patent/PT2432804E/pt

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/40—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum bacterial
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1271—Micrococcaceae (F); Staphylococcaceae (F), e.g. Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56938—Staphylococcus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/10—Detection of antigens from microorganism in sample from host

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Pregnancy & Childbirth (AREA)
PT107204166T 2009-05-18 2010-05-18 Anticorpos ou seus fragmentos direcionados contra um epítopo de staphylococcus aureus de isaa ou isab PT2432804E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17913309P 2009-05-18 2009-05-18

Publications (1)

Publication Number Publication Date
PT2432804E true PT2432804E (pt) 2015-06-25

Family

ID=42316060

Family Applications (1)

Application Number Title Priority Date Filing Date
PT107204166T PT2432804E (pt) 2009-05-18 2010-05-18 Anticorpos ou seus fragmentos direcionados contra um epítopo de staphylococcus aureus de isaa ou isab

Country Status (13)

Country Link
US (3) US8609102B2 (cg-RX-API-DMAC10.html)
EP (1) EP2432804B1 (cg-RX-API-DMAC10.html)
JP (2) JP5882892B2 (cg-RX-API-DMAC10.html)
CN (1) CN102695724B (cg-RX-API-DMAC10.html)
AU (1) AU2010251156C1 (cg-RX-API-DMAC10.html)
BR (1) BRPI1010911A2 (cg-RX-API-DMAC10.html)
CA (1) CA2761886A1 (cg-RX-API-DMAC10.html)
ES (1) ES2537437T3 (cg-RX-API-DMAC10.html)
MX (1) MX2011012248A (cg-RX-API-DMAC10.html)
PL (1) PL2432804T3 (cg-RX-API-DMAC10.html)
PT (1) PT2432804E (cg-RX-API-DMAC10.html)
RU (1) RU2560415C2 (cg-RX-API-DMAC10.html)
WO (1) WO2010133600A1 (cg-RX-API-DMAC10.html)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2010251156C1 (en) * 2009-05-18 2015-02-05 Julius-Maximilians-Universitat Wurzburg Antibodies or fragments thereof directed against a Staphylococcus aureus epitope of IsaA or IsaB
JP2014534169A (ja) * 2011-09-23 2014-12-18 ユリウス・マクシミリアンス−ウニヴェルジテート・ヴュルツブルクＪｕｌｉｕｓ Ｍａｘｉｍｉｌｉａｎｓ−Ｕｎｉｖｅｒｓｉｔａｅｔ Ｗｕｅｒｚｂｕｒｇ Ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓエピトープ結合部位を形成するペプチドまたはペプチドの配置
WO2015088346A1 (en) 2013-12-13 2015-06-18 Rijksuniversiteit Groningen Antibodies against staphylococcus aureus and uses thereof.
MX2021000889A (es) 2018-07-24 2021-04-28 Medimmune Llc Anticuerpo dirigido contra el factor de agregación a (clfa) de s. aureus.
KR102341805B1 (ko) * 2019-11-27 2021-12-22 주식회사 하울바이오 황색포도상구균에 특이적으로 반응하는 항-IsaA G4 항체 및 이의 용도
KR102341804B1 (ko) * 2019-11-27 2021-12-22 주식회사 하울바이오 황색포도상구균을 억제하는 항-IsaA F10 항체 및 이의 용도
US20230357373A1 (en) * 2019-12-17 2023-11-09 Mie University Methods and compositions for evaluating and treating fibrosis
WO2022250205A1 (ko) * 2021-05-25 2022-12-01 주식회사 하울바이오 항-IsaA F10 항체의 아토피 피부염 예방 및 개선 용도

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4238806A1 (en) * 1991-11-18 1993-05-27 Dainabot Co Methicillin-resistant staphylococcus aureus (MRSA)detection method - by detection of MRSA penicillin binding protein (PBP)2 antigen-antibody complex, and synthetic MRSA PBP2 peptides
FR2746398B1 (fr) * 1996-03-21 1998-04-30 Bio Merieux Anticorps specifique de staphylococcus aureaus, et utilisations
RU2144190C1 (ru) * 1998-01-13 2000-01-10 Катханов Али Муратович Способ диагностики стафилококковой инфекции
GB0014907D0 (en) * 2000-06-20 2000-08-09 Univ Sheffield Antigenic polypeptides
GB0127983D0 (en) * 2001-11-22 2002-01-16 Neutec Pharma Plc Treatment of micro-organism infection
KR20070104590A (ko) * 2005-01-10 2007-10-26 나비 바이오파마슈티컬즈 스타필로코쿠스 아우레우스 감염을 치료하는 방법
AU2010251156C1 (en) * 2009-05-18 2015-02-05 Julius-Maximilians-Universitat Wurzburg Antibodies or fragments thereof directed against a Staphylococcus aureus epitope of IsaA or IsaB

Also Published As

Publication number Publication date
RU2560415C2 (ru) 2015-08-20
US20160109449A1 (en) 2016-04-21
AU2010251156B2 (en) 2014-10-09
JP2016047828A (ja) 2016-04-07
MX2011012248A (es) 2012-02-29
RU2011146424A (ru) 2013-06-27
AU2010251156C1 (en) 2015-02-05
US20120100151A1 (en) 2012-04-26
EP2432804B1 (en) 2015-02-25
US9260511B2 (en) 2016-02-16
BRPI1010911A2 (pt) 2019-09-24
CN102695724A (zh) 2012-09-26
AU2010251156A1 (en) 2011-11-24
JP2012527423A (ja) 2012-11-08
JP5882892B2 (ja) 2016-03-09
US20140072570A1 (en) 2014-03-13
WO2010133600A1 (en) 2010-11-25
PL2432804T3 (pl) 2015-08-31
EP2432804A1 (en) 2012-03-28
ES2537437T3 (es) 2015-06-08
US8609102B2 (en) 2013-12-17
CN102695724B (zh) 2016-08-24
US9658230B2 (en) 2017-05-23
CA2761886A1 (en) 2010-11-25

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