JP5882892B2 - 黄色ブドウ球菌エピトープＩｓａＡまたはＩｓａＢに対する抗体またはそれらのフラグメント - Google Patents

黄色ブドウ球菌エピトープＩｓａＡまたはＩｓａＢに対する抗体またはそれらのフラグメント Download PDF

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JP5882892B2
JP5882892B2 JP2012511263A JP2012511263A JP5882892B2 JP 5882892 B2 JP5882892 B2 JP 5882892B2 JP 2012511263 A JP2012511263 A JP 2012511263A JP 2012511263 A JP2012511263 A JP 2012511263A JP 5882892 B2 JP5882892 B2 JP 5882892B2
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antibody
fragment
aureus
antibodies
cell line
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JP2012527423A5 (cg-RX-API-DMAC10.html
JP2012527423A (ja
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オールセン，クヌート
ロレンツ，ウド
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University of Würzburg
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University of Würzburg
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/40—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum bacterial
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1271—Micrococcaceae (F); Staphylococcaceae (F), e.g. Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56938—Staphylococcus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00—Immunoassays for the detection of microorganisms
    • G01N2469/10—Detection of antigens from microorganism in sample from host

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Pregnancy & Childbirth (AREA)
JP2012511263A 2009-05-18 2010-05-18 黄色ブドウ球菌エピトープＩｓａＡまたはＩｓａＢに対する抗体またはそれらのフラグメント Expired - Fee Related JP5882892B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17913309P 2009-05-18 2009-05-18
US61/179,133 2009-05-18
PCT/EP2010/056827 WO2010133600A1 (en) 2009-05-18 2010-05-18 Antibodies or fragments thereof directed against a staphylococcus aureus epitope of isaa or isab

Related Child Applications (1)

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JP2015201433A Division JP2016047828A (ja) 2009-05-18 2015-10-09 黄色ブドウ球菌エピトープＩｓａＡまたはＩｓａＢに対する抗体またはそれらのフラグメント

Publications (3)

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JP2012527423A JP2012527423A (ja) 2012-11-08
JP2012527423A5 JP2012527423A5 (cg-RX-API-DMAC10.html) 2013-09-19
JP5882892B2 true JP5882892B2 (ja) 2016-03-09

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JP2012511263A Expired - Fee Related JP5882892B2 (ja) 2009-05-18 2010-05-18 黄色ブドウ球菌エピトープＩｓａＡまたはＩｓａＢに対する抗体またはそれらのフラグメント
JP2015201433A Pending JP2016047828A (ja) 2009-05-18 2015-10-09 黄色ブドウ球菌エピトープＩｓａＡまたはＩｓａＢに対する抗体またはそれらのフラグメント

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JP2015201433A Pending JP2016047828A (ja) 2009-05-18 2015-10-09 黄色ブドウ球菌エピトープＩｓａＡまたはＩｓａＢに対する抗体またはそれらのフラグメント

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US (3) US8609102B2 (cg-RX-API-DMAC10.html)
EP (1) EP2432804B1 (cg-RX-API-DMAC10.html)
JP (2) JP5882892B2 (cg-RX-API-DMAC10.html)
CN (1) CN102695724B (cg-RX-API-DMAC10.html)
AU (1) AU2010251156C1 (cg-RX-API-DMAC10.html)
BR (1) BRPI1010911A2 (cg-RX-API-DMAC10.html)
CA (1) CA2761886A1 (cg-RX-API-DMAC10.html)
ES (1) ES2537437T3 (cg-RX-API-DMAC10.html)
MX (1) MX2011012248A (cg-RX-API-DMAC10.html)
PL (1) PL2432804T3 (cg-RX-API-DMAC10.html)
PT (1) PT2432804E (cg-RX-API-DMAC10.html)
RU (1) RU2560415C2 (cg-RX-API-DMAC10.html)
WO (1) WO2010133600A1 (cg-RX-API-DMAC10.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016047828A (ja) * 2009-05-18 2016-04-07 ユリウス・マクシミリアンス−ウニヴェルジテート・ヴュルツブルクＪｕｌｉｕｓ Ｍａｘｉｍｉｌｉａｎｓ−Ｕｎｉｖｅｒｓｉｔａｅｔ Ｗｕｅｒｚｂｕｒｇ 黄色ブドウ球菌エピトープＩｓａＡまたはＩｓａＢに対する抗体またはそれらのフラグメント

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014534169A (ja) * 2011-09-23 2014-12-18 ユリウス・マクシミリアンス−ウニヴェルジテート・ヴュルツブルクＪｕｌｉｕｓ Ｍａｘｉｍｉｌｉａｎｓ−Ｕｎｉｖｅｒｓｉｔａｅｔ Ｗｕｅｒｚｂｕｒｇ Ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓエピトープ結合部位を形成するペプチドまたはペプチドの配置
WO2015088346A1 (en) 2013-12-13 2015-06-18 Rijksuniversiteit Groningen Antibodies against staphylococcus aureus and uses thereof.
MX2021000889A (es) 2018-07-24 2021-04-28 Medimmune Llc Anticuerpo dirigido contra el factor de agregación a (clfa) de s. aureus.
KR102341805B1 (ko) * 2019-11-27 2021-12-22 주식회사 하울바이오 황색포도상구균에 특이적으로 반응하는 항-IsaA G4 항체 및 이의 용도
KR102341804B1 (ko) * 2019-11-27 2021-12-22 주식회사 하울바이오 황색포도상구균을 억제하는 항-IsaA F10 항체 및 이의 용도
US20230357373A1 (en) * 2019-12-17 2023-11-09 Mie University Methods and compositions for evaluating and treating fibrosis
WO2022250205A1 (ko) * 2021-05-25 2022-12-01 주식회사 하울바이오 항-IsaA F10 항체의 아토피 피부염 예방 및 개선 용도

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4238806A1 (en) * 1991-11-18 1993-05-27 Dainabot Co Methicillin-resistant staphylococcus aureus (MRSA)detection method - by detection of MRSA penicillin binding protein (PBP)2 antigen-antibody complex, and synthetic MRSA PBP2 peptides
FR2746398B1 (fr) * 1996-03-21 1998-04-30 Bio Merieux Anticorps specifique de staphylococcus aureaus, et utilisations
RU2144190C1 (ru) * 1998-01-13 2000-01-10 Катханов Али Муратович Способ диагностики стафилококковой инфекции
GB0014907D0 (en) * 2000-06-20 2000-08-09 Univ Sheffield Antigenic polypeptides
GB0127983D0 (en) * 2001-11-22 2002-01-16 Neutec Pharma Plc Treatment of micro-organism infection
KR20070104590A (ko) * 2005-01-10 2007-10-26 나비 바이오파마슈티컬즈 스타필로코쿠스 아우레우스 감염을 치료하는 방법
AU2010251156C1 (en) * 2009-05-18 2015-02-05 Julius-Maximilians-Universitat Wurzburg Antibodies or fragments thereof directed against a Staphylococcus aureus epitope of IsaA or IsaB

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016047828A (ja) * 2009-05-18 2016-04-07 ユリウス・マクシミリアンス−ウニヴェルジテート・ヴュルツブルクＪｕｌｉｕｓ Ｍａｘｉｍｉｌｉａｎｓ−Ｕｎｉｖｅｒｓｉｔａｅｔ Ｗｕｅｒｚｂｕｒｇ 黄色ブドウ球菌エピトープＩｓａＡまたはＩｓａＢに対する抗体またはそれらのフラグメント

Also Published As

Publication number Publication date
RU2560415C2 (ru) 2015-08-20
US20160109449A1 (en) 2016-04-21
PT2432804E (pt) 2015-06-25
AU2010251156B2 (en) 2014-10-09
JP2016047828A (ja) 2016-04-07
MX2011012248A (es) 2012-02-29
RU2011146424A (ru) 2013-06-27
AU2010251156C1 (en) 2015-02-05
US20120100151A1 (en) 2012-04-26
EP2432804B1 (en) 2015-02-25
US9260511B2 (en) 2016-02-16
BRPI1010911A2 (pt) 2019-09-24
CN102695724A (zh) 2012-09-26
AU2010251156A1 (en) 2011-11-24
JP2012527423A (ja) 2012-11-08
US20140072570A1 (en) 2014-03-13
WO2010133600A1 (en) 2010-11-25
PL2432804T3 (pl) 2015-08-31
EP2432804A1 (en) 2012-03-28
ES2537437T3 (es) 2015-06-08
US8609102B2 (en) 2013-12-17
CN102695724B (zh) 2016-08-24
US9658230B2 (en) 2017-05-23
CA2761886A1 (en) 2010-11-25

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