PT2150253E - Utilização de 4-ciclopropilmetoxi-n-(3,5-dicloro-1-oxidopiridin- 4-il)-5-(metoxi)piridina-2-carboxamida para o tratamento de traumatismos da medula espinal - Google Patents

Utilização de 4-ciclopropilmetoxi-n-(3,5-dicloro-1-oxidopiridin- 4-il)-5-(metoxi)piridina-2-carboxamida para o tratamento de traumatismos da medula espinal Download PDF

Info

Publication number
PT2150253E
PT2150253E PT08787962T PT08787962T PT2150253E PT 2150253 E PT2150253 E PT 2150253E PT 08787962 T PT08787962 T PT 08787962T PT 08787962 T PT08787962 T PT 08787962T PT 2150253 E PT2150253 E PT 2150253E
Authority
PT
Portugal
Prior art keywords
oxidopyridin
cyclopropylmethoxy
carboxamide
dichloro
pyridine
Prior art date
Application number
PT08787962T
Other languages
English (en)
Inventor
Philippe Delay-Goyet
Badia Ferzaz
Jocelyne Lolivier
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of PT2150253E publication Critical patent/PT2150253E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
PT08787962T 2007-04-19 2008-04-16 Utilização de 4-ciclopropilmetoxi-n-(3,5-dicloro-1-oxidopiridin- 4-il)-5-(metoxi)piridina-2-carboxamida para o tratamento de traumatismos da medula espinal PT2150253E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0702851A FR2915098B1 (fr) 2007-04-19 2007-04-19 Utilisation du 4-cyclopropylmethoxy-n-(3,5-dichloro-1-oxydo- pyridin-4-yl)-5-(methoxy)pyridine-2-carboxamide pour le traitement des traumatismes de la moelle epiniere

Publications (1)

Publication Number Publication Date
PT2150253E true PT2150253E (pt) 2011-06-17

Family

ID=38779706

Family Applications (1)

Application Number Title Priority Date Filing Date
PT08787962T PT2150253E (pt) 2007-04-19 2008-04-16 Utilização de 4-ciclopropilmetoxi-n-(3,5-dicloro-1-oxidopiridin- 4-il)-5-(metoxi)piridina-2-carboxamida para o tratamento de traumatismos da medula espinal

Country Status (33)

Country Link
US (1) US8592443B2 (pt)
EP (1) EP2150253B1 (pt)
JP (1) JP5386477B2 (pt)
KR (1) KR101470043B1 (pt)
CN (1) CN101674829B (pt)
AR (1) AR066106A1 (pt)
AT (1) ATE503481T1 (pt)
AU (1) AU2008257321B2 (pt)
BR (1) BRPI0810446A2 (pt)
CA (1) CA2684172C (pt)
CL (1) CL2008001134A1 (pt)
CY (1) CY1111779T1 (pt)
DE (1) DE602008005873D1 (pt)
DK (1) DK2150253T3 (pt)
EA (1) EA015355B1 (pt)
ES (1) ES2363056T3 (pt)
FR (1) FR2915098B1 (pt)
HK (1) HK1142000A1 (pt)
HR (1) HRP20110459T1 (pt)
IL (1) IL201451A (pt)
JO (1) JO2662B1 (pt)
MA (1) MA31369B1 (pt)
ME (1) ME00934B (pt)
MX (1) MX2009011285A (pt)
MY (1) MY146657A (pt)
NZ (1) NZ580483A (pt)
PA (1) PA8776601A1 (pt)
PL (1) PL2150253T3 (pt)
PT (1) PT2150253E (pt)
SI (1) SI2150253T1 (pt)
TW (1) TWI411435B (pt)
UY (1) UY31033A1 (pt)
WO (1) WO2008145840A2 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2915099B1 (fr) 2007-04-19 2009-06-05 Sanofi Aventis Sa Utilisation du 4-cyclopropylmethoxy-n-(3,5-dichloro-1-oxydo- pyridin-4-yl)-5-(methoxy)pyridine-2-carboxamide pour le traitement des traumatismes craniens
RU2635094C2 (ru) * 2012-11-28 2017-11-09 Санофи Способ получения 4-(циклопропилметокси)-n-(3,5-дихлор-1-оксидо-4-пиридил)-5-метоксипиридин-2-карбоксамида
RU2621894C2 (ru) * 2012-11-28 2017-06-08 Санофи Способ получения новых кристаллических форм-4(циклопропилметокси)-n-(3, 5-дихлор-1-оксидопиридин-4-ил)-5-метоксипиридин-2-карбоксамида и его кристаллические формы
JP2024503727A (ja) 2021-01-20 2024-01-26 アルト ニューロサイエンス，インコーポレーテッド うつ病及び関連する状態の治療のための併用薬物戦略としてのｃＡＭＰシグナル伝達の強化

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4193926A (en) * 1974-03-20 1980-03-18 Schering Aktiengesellschaft 4-(Polyalkoxy phenyl)-2-pyrrolidones
EP0711282B1 (en) * 1993-07-28 2002-06-05 Aventis Pharma Limited Compounds as pde iv and tnf inhibitors
GB9401460D0 (en) 1994-01-26 1994-03-23 Rhone Poulenc Rorer Ltd Compositions of matter
GB9507297D0 (en) 1995-04-07 1995-05-31 Rh Ne Poulenc Rorer Limited New composition of matter
US6196968B1 (en) 1997-06-02 2001-03-06 General Surgical Innovations, Inc. Direct vision subcutaneous tissue retractor and method for use
US6177077B1 (en) * 1999-02-24 2001-01-23 Edward L. Tobinick TNT inhibitors for the treatment of neurological disorders
JP2003519139A (ja) * 1999-12-23 2003-06-17 アイコス コーポレイション 環状ａｍｐ−特異的ホスホジエステラーゼ阻害剤
EP1370211A4 (en) * 2001-03-02 2005-02-09 Bristol Myers Squibb Co SIMULTANEOUS ADMINISTRATION OF MELANOCORTIN RECEPTOR AGONISTS AND A PHOSPHODIESTERASE HEMMER FOR THE TREATMENT OF DISEASES RELATED TO CYCLIC AMP
AU2003281219A1 (en) 2002-07-02 2004-01-23 Bernard Cote Di-aryl-substituted-ethane pyridone pde4 inhibitors
WO2004067006A1 (en) 2003-01-27 2004-08-12 Pharmacia Corporation Combination of a pde iv inhibitor and a tnf-alpha antagonist
WO2005034870A2 (en) * 2003-10-07 2005-04-21 Renovis, Inc. Amide compounds and ion channel ligands and uses thereof
US20070049611A1 (en) * 2005-06-10 2007-03-01 Talamas Francisco X Phosphodiesterase 4 inhibitors
US20070021451A1 (en) * 2005-07-20 2007-01-25 Hamamatsu University School Of Medicine Method for preventing or treating neurologic damage after spinal cord injury

Also Published As

Publication number Publication date
HK1142000A1 (pt) 2010-11-26
MY146657A (en) 2012-09-14
CN101674829B (zh) 2012-01-18
DE602008005873D1 (de) 2011-05-12
UY31033A1 (es) 2008-11-28
NZ580483A (en) 2011-06-30
US20100137370A1 (en) 2010-06-03
JO2662B1 (en) 2012-06-17
CL2008001134A1 (es) 2009-01-16
DK2150253T3 (da) 2011-07-25
EA200970969A1 (ru) 2010-02-26
JP5386477B2 (ja) 2014-01-15
IL201451A (en) 2013-04-30
ATE503481T1 (de) 2011-04-15
SI2150253T1 (sl) 2011-07-29
ME00934B (me) 2012-06-20
FR2915098A1 (fr) 2008-10-24
IL201451A0 (en) 2010-05-31
CN101674829A (zh) 2010-03-17
HRP20110459T1 (hr) 2011-07-31
KR20090130063A (ko) 2009-12-17
TW200911248A (en) 2009-03-16
EA015355B1 (ru) 2011-06-30
EP2150253A2 (fr) 2010-02-10
ES2363056T3 (es) 2011-07-19
BRPI0810446A2 (pt) 2014-10-14
CY1111779T1 (el) 2015-10-07
JP2010524905A (ja) 2010-07-22
CA2684172C (fr) 2015-10-27
AU2008257321B2 (en) 2013-08-15
MX2009011285A (es) 2009-11-02
AR066106A1 (es) 2009-07-22
EP2150253B1 (fr) 2011-03-30
WO2008145840A3 (fr) 2009-06-25
US8592443B2 (en) 2013-11-26
FR2915098B1 (fr) 2009-06-05
CA2684172A1 (fr) 2008-12-04
PL2150253T3 (pl) 2011-08-31
AU2008257321A1 (en) 2008-12-04
PA8776601A1 (es) 2008-11-19
WO2008145840A2 (fr) 2008-12-04
KR101470043B1 (ko) 2014-12-05
MA31369B1 (fr) 2010-05-03
TWI411435B (zh) 2013-10-11

Similar Documents

Publication Publication Date Title
EP1870051A4 (en) MEDICAL TREATMENT APPARATUS
IL191832A0 (en) Pyridiazinone derivatives for the treatment of tumours
HK1139861A1 (en) Pde7 inhibitors for use in the treatment of movement disorders 7(pde7)
EP1913879A4 (en) MEDICAL TREATMENT DEVICE
IL205137A0 (en) 5-cyanothienopyridines for the treatment of tumours
ZA201005282B (en) Substituted oxindole-derivatives and the use thereof for the treatment of vasopressin-dependent illnesses
IL201451A0 (en) Use of 4 - cyclopropylmethoxy - n - (3, 5 - dichloro - 1 - oxidopyridin - 4 - yl) - 5 - (methoxy) pyridine - 2 - carboxamide for the treatment of spinal cord traumas
IL192933A0 (en) Benzoisoindole derivatives for the treatment of pain
ZA201005306B (en) 5-o-substituted 3-n-phenyl-1,3,4-oxadiazolones for medical use
GB0712613D0 (en) Therapy or treatment apparatus
GB0710277D0 (en) Use of antivirals in the treatment of medical disorders
GB0721616D0 (en) Treatment of spinal cord injury
IL201447A0 (en) Use of 4 - cyclopropylmethoxy - n - (3, 5 - dichloro - 1 - oxidopyridin - 4 - yl) - 5 - (methoxy) pyridine - 2 - carboxamide for the treatment of cranial traumas
ZA200907251B (en) Use of 4-cyclopropylmethoxy-n-(3,5-dichloro-1-oxidopyridin-4-yl)-5-(methoxy)pyridine-2-carboxamide for the treatment of motor disorders related to parkinson's disease
TH0801001896A (th) การใช้ 4-ไซโคลโพรพิลเมธอกซิ-n-(3,5-ไดคลอโร-1-ออกซิโด-ไพริดิน-4-อิล)-5-(เมธอกซิ)ไพริดีน-2-คาร์บอกซามีด ในการรักษาการบาดเจ็บไขสันหลัง
GB0700886D0 (en) Medical treatment
GB0704664D0 (en) Treatment device 3
GB0704662D0 (en) Treatment device 2
ZA200806180B (en) Benzoisoindole derivatives for the treatment of pain
GB0722338D0 (en) Novel use and treatment
IL194467A0 (en) Infant treatment apparatus
GB0600817D0 (en) Medical treatment