DE602008005873D1 - Verwendung von 4-cyclopropylmethoxy-n-(3,5-dichlor-1-oxidopyridin-4-yl)-5-(methoxy)-pyridin-2-carboxamid zur behandlung von rückenmarksverletzungen - Google Patents

Verwendung von 4-cyclopropylmethoxy-n-(3,5-dichlor-1-oxidopyridin-4-yl)-5-(methoxy)-pyridin-2-carboxamid zur behandlung von rückenmarksverletzungen

Info

Publication number
DE602008005873D1
DE602008005873D1 DE602008005873T DE602008005873T DE602008005873D1 DE 602008005873 D1 DE602008005873 D1 DE 602008005873D1 DE 602008005873 T DE602008005873 T DE 602008005873T DE 602008005873 T DE602008005873 T DE 602008005873T DE 602008005873 D1 DE602008005873 D1 DE 602008005873D1
Authority
DE
Germany
Prior art keywords
oxidopyridin
dichlor
cyclopropylmethoxy
carboxamide
injuries
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602008005873T
Other languages
English (en)
Inventor
Philippe Delay-Goyet
Badia Ferzaz
Jocelyne Lolivier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Aventis France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis France filed Critical Sanofi Aventis France
Publication of DE602008005873D1 publication Critical patent/DE602008005873D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
DE602008005873T 2007-04-19 2008-04-16 Verwendung von 4-cyclopropylmethoxy-n-(3,5-dichlor-1-oxidopyridin-4-yl)-5-(methoxy)-pyridin-2-carboxamid zur behandlung von rückenmarksverletzungen Active DE602008005873D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0702851A FR2915098B1 (fr) 2007-04-19 2007-04-19 Utilisation du 4-cyclopropylmethoxy-n-(3,5-dichloro-1-oxydo- pyridin-4-yl)-5-(methoxy)pyridine-2-carboxamide pour le traitement des traumatismes de la moelle epiniere
PCT/FR2008/000533 WO2008145840A2 (fr) 2007-04-19 2008-04-16 Utilisation du 4-cyclopropylmethoxy-n-(3,5-dichloro-1 -oxydo- pyridin-4-yl)-5-(methoxy)pyridine-2-carboxamide pour le traitement des traumatismes de la moelle epiniere

Publications (1)

Publication Number Publication Date
DE602008005873D1 true DE602008005873D1 (de) 2011-05-12

Family

ID=38779706

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602008005873T Active DE602008005873D1 (de) 2007-04-19 2008-04-16 Verwendung von 4-cyclopropylmethoxy-n-(3,5-dichlor-1-oxidopyridin-4-yl)-5-(methoxy)-pyridin-2-carboxamid zur behandlung von rückenmarksverletzungen

Country Status (33)

Country Link
US (1) US8592443B2 (de)
EP (1) EP2150253B1 (de)
JP (1) JP5386477B2 (de)
KR (1) KR101470043B1 (de)
CN (1) CN101674829B (de)
AR (1) AR066106A1 (de)
AT (1) ATE503481T1 (de)
AU (1) AU2008257321B2 (de)
BR (1) BRPI0810446A2 (de)
CA (1) CA2684172C (de)
CL (1) CL2008001134A1 (de)
CY (1) CY1111779T1 (de)
DE (1) DE602008005873D1 (de)
DK (1) DK2150253T3 (de)
EA (1) EA015355B1 (de)
ES (1) ES2363056T3 (de)
FR (1) FR2915098B1 (de)
HK (1) HK1142000A1 (de)
HR (1) HRP20110459T1 (de)
IL (1) IL201451A (de)
JO (1) JO2662B1 (de)
MA (1) MA31369B1 (de)
ME (1) ME00934B (de)
MX (1) MX2009011285A (de)
MY (1) MY146657A (de)
NZ (1) NZ580483A (de)
PA (1) PA8776601A1 (de)
PL (1) PL2150253T3 (de)
PT (1) PT2150253E (de)
SI (1) SI2150253T1 (de)
TW (1) TWI411435B (de)
UY (1) UY31033A1 (de)
WO (1) WO2008145840A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2915099B1 (fr) 2007-04-19 2009-06-05 Sanofi Aventis Sa Utilisation du 4-cyclopropylmethoxy-n-(3,5-dichloro-1-oxydo- pyridin-4-yl)-5-(methoxy)pyridine-2-carboxamide pour le traitement des traumatismes craniens
CN104955820A (zh) * 2012-11-28 2015-09-30 赛诺菲 4-(环丙基甲氧基)-n-(3,5-二氯-1-氧化-吡啶-4-基)-5-甲氧基吡啶-2-甲酰胺的制备方法
EP2935219A1 (de) * 2012-11-28 2015-10-28 Sanofi Verfahren zur herstellung von kristallformen von 4-(cyclopropylmethoxy)n-(3,5-dichlor-1-oxidopyridyn-4-yl-)5-methoxypyridin-2-carboxamid und kristallformen davon
WO2022159632A1 (en) 2021-01-20 2022-07-28 Alto Neuroscience, Inc. Enhancement of camp signaling as a combination drug strategy for the treatment of depression and related conditions

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4193926A (en) * 1974-03-20 1980-03-18 Schering Aktiengesellschaft 4-(Polyalkoxy phenyl)-2-pyrrolidones
DK0711282T3 (da) * 1993-07-28 2002-09-16 Aventis Pharma Ltd Forbindelser som PDE IV og TNF inhibitorer
GB9401460D0 (en) 1994-01-26 1994-03-23 Rhone Poulenc Rorer Ltd Compositions of matter
GB9507297D0 (en) 1995-04-07 1995-05-31 Rh Ne Poulenc Rorer Limited New composition of matter
US6196968B1 (en) 1997-06-02 2001-03-06 General Surgical Innovations, Inc. Direct vision subcutaneous tissue retractor and method for use
US6177077B1 (en) * 1999-02-24 2001-01-23 Edward L. Tobinick TNT inhibitors for the treatment of neurological disorders
CA2395196C (en) * 1999-12-23 2006-02-21 Icos Corporation Cyclic amp-specific phosphodiesterase inhibitors
CA2439691A1 (en) * 2001-03-02 2002-09-12 Bristol-Myers Squibb Company Co-administration of melanocortin receptor agonist and phosphodiesterase inhibitor for treatment of cyclic-amp associated disorders
EP1519922A1 (de) 2002-07-02 2005-04-06 Merck Frosst Canada & Co. Diaryl-substituierte ethanpyridone als pde4 inhibitoren
WO2004067006A1 (en) 2003-01-27 2004-08-12 Pharmacia Corporation Combination of a pde iv inhibitor and a tnf-alpha antagonist
WO2005032493A2 (en) * 2003-10-07 2005-04-14 Renovis, Inc. Amide compounds as ion channel ligands and uses thereof
EP1888528A2 (de) * 2005-06-10 2008-02-20 Memory Pharmaceuticals Corporation Phosphodiesterase-4-inhibitoren
US20070021451A1 (en) * 2005-07-20 2007-01-25 Hamamatsu University School Of Medicine Method for preventing or treating neurologic damage after spinal cord injury

Also Published As

Publication number Publication date
AR066106A1 (es) 2009-07-22
JP2010524905A (ja) 2010-07-22
EP2150253B1 (de) 2011-03-30
CN101674829B (zh) 2012-01-18
FR2915098A1 (fr) 2008-10-24
CA2684172A1 (fr) 2008-12-04
TWI411435B (zh) 2013-10-11
KR20090130063A (ko) 2009-12-17
EA015355B1 (ru) 2011-06-30
EP2150253A2 (de) 2010-02-10
FR2915098B1 (fr) 2009-06-05
US20100137370A1 (en) 2010-06-03
WO2008145840A2 (fr) 2008-12-04
KR101470043B1 (ko) 2014-12-05
MX2009011285A (es) 2009-11-02
MY146657A (en) 2012-09-14
UY31033A1 (es) 2008-11-28
HK1142000A1 (de) 2010-11-26
CN101674829A (zh) 2010-03-17
DK2150253T3 (da) 2011-07-25
JP5386477B2 (ja) 2014-01-15
PT2150253E (pt) 2011-06-17
WO2008145840A3 (fr) 2009-06-25
AU2008257321B2 (en) 2013-08-15
NZ580483A (en) 2011-06-30
IL201451A0 (en) 2010-05-31
CL2008001134A1 (es) 2009-01-16
PA8776601A1 (es) 2008-11-19
AU2008257321A1 (en) 2008-12-04
US8592443B2 (en) 2013-11-26
IL201451A (en) 2013-04-30
ES2363056T3 (es) 2011-07-19
PL2150253T3 (pl) 2011-08-31
CY1111779T1 (el) 2015-10-07
TW200911248A (en) 2009-03-16
EA200970969A1 (ru) 2010-02-26
CA2684172C (fr) 2015-10-27
ME00934B (me) 2012-06-20
ATE503481T1 (de) 2011-04-15
JO2662B1 (en) 2012-06-17
HRP20110459T1 (hr) 2011-07-31
BRPI0810446A2 (pt) 2014-10-14
MA31369B1 (fr) 2010-05-03
SI2150253T1 (sl) 2011-07-29

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