MX2009011285A - Uso de 4-ciclopropilmetoxi-n-(3,5-dicloro-1-oxido-piridin-4-il)-5- (metoxi)piridin-2-carboxamida para el tratamiento de los traumatismos de la medula espinal. - Google Patents

Uso de 4-ciclopropilmetoxi-n-(3,5-dicloro-1-oxido-piridin-4-il)-5- (metoxi)piridin-2-carboxamida para el tratamiento de los traumatismos de la medula espinal.

Info

Publication number
MX2009011285A
MX2009011285A MX2009011285A MX2009011285A MX2009011285A MX 2009011285 A MX2009011285 A MX 2009011285A MX 2009011285 A MX2009011285 A MX 2009011285A MX 2009011285 A MX2009011285 A MX 2009011285A MX 2009011285 A MX2009011285 A MX 2009011285A
Authority
MX
Mexico
Prior art keywords
oxidopyridin
cyclopropylmethoxy
carboxamide
dichloro
pyridine
Prior art date
Application number
MX2009011285A
Other languages
English (en)
Inventor
Philippe Delay-Goyet
Badia Ferzaz
Jocelyne Lolivier
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of MX2009011285A publication Critical patent/MX2009011285A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

La invención se refiere al uso de 4-ciclopropilmetoxi-N-(3,5-diclo ro-1-óxido-piridin-4-il)-5-(metoxi)piridin-2-carboxamida para la preparación de un medicamento para uso en el tratamiento de los traumatismos de la médula espinal.
MX2009011285A 2007-04-19 2008-04-16 Uso de 4-ciclopropilmetoxi-n-(3,5-dicloro-1-oxido-piridin-4-il)-5- (metoxi)piridin-2-carboxamida para el tratamiento de los traumatismos de la medula espinal. MX2009011285A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0702851A FR2915098B1 (fr) 2007-04-19 2007-04-19 Utilisation du 4-cyclopropylmethoxy-n-(3,5-dichloro-1-oxydo- pyridin-4-yl)-5-(methoxy)pyridine-2-carboxamide pour le traitement des traumatismes de la moelle epiniere
PCT/FR2008/000533 WO2008145840A2 (fr) 2007-04-19 2008-04-16 Utilisation du 4-cyclopropylmethoxy-n-(3,5-dichloro-1 -oxydo- pyridin-4-yl)-5-(methoxy)pyridine-2-carboxamide pour le traitement des traumatismes de la moelle epiniere

Publications (1)

Publication Number Publication Date
MX2009011285A true MX2009011285A (es) 2009-11-02

Family

ID=38779706

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009011285A MX2009011285A (es) 2007-04-19 2008-04-16 Uso de 4-ciclopropilmetoxi-n-(3,5-dicloro-1-oxido-piridin-4-il)-5- (metoxi)piridin-2-carboxamida para el tratamiento de los traumatismos de la medula espinal.

Country Status (33)

Country Link
US (1) US8592443B2 (es)
EP (1) EP2150253B1 (es)
JP (1) JP5386477B2 (es)
KR (1) KR101470043B1 (es)
CN (1) CN101674829B (es)
AR (1) AR066106A1 (es)
AT (1) ATE503481T1 (es)
AU (1) AU2008257321B2 (es)
BR (1) BRPI0810446A2 (es)
CA (1) CA2684172C (es)
CL (1) CL2008001134A1 (es)
CY (1) CY1111779T1 (es)
DE (1) DE602008005873D1 (es)
DK (1) DK2150253T3 (es)
EA (1) EA015355B1 (es)
ES (1) ES2363056T3 (es)
FR (1) FR2915098B1 (es)
HK (1) HK1142000A1 (es)
HR (1) HRP20110459T1 (es)
IL (1) IL201451A (es)
JO (1) JO2662B1 (es)
MA (1) MA31369B1 (es)
ME (1) ME00934B (es)
MX (1) MX2009011285A (es)
MY (1) MY146657A (es)
NZ (1) NZ580483A (es)
PA (1) PA8776601A1 (es)
PL (1) PL2150253T3 (es)
PT (1) PT2150253E (es)
SI (1) SI2150253T1 (es)
TW (1) TWI411435B (es)
UY (1) UY31033A1 (es)
WO (1) WO2008145840A2 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2915099B1 (fr) 2007-04-19 2009-06-05 Sanofi Aventis Sa Utilisation du 4-cyclopropylmethoxy-n-(3,5-dichloro-1-oxydo- pyridin-4-yl)-5-(methoxy)pyridine-2-carboxamide pour le traitement des traumatismes craniens
MX2015006807A (es) * 2012-11-28 2016-01-14 Sanofi Sa Metodo de preparacion de formas cristalinas de la 4-(ciclopropilmetoxi)-n-(3,5-dicloro-1-oxidopiridin-4-il)-5-metox ipiridin-2-carboxamida y sus formas cristalinas.
WO2014083106A1 (en) * 2012-11-28 2014-06-05 Sanofi Process for preparing 4-(cyclopropylmethoxy)-n-(3,5-dichloro-1-oxido-4-pyridyl)-5-methoxypyridine-2-carboxamide
EP4281065A1 (en) 2021-01-20 2023-11-29 Alto Neuroscience, Inc. Enhancement of camp signaling as a combination drug strategy for the treatment of depression and related conditions

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4193926A (en) 1974-03-20 1980-03-18 Schering Aktiengesellschaft 4-(Polyalkoxy phenyl)-2-pyrrolidones
ATE218549T1 (de) 1993-07-28 2002-06-15 Aventis Pharma Ltd Verbindungen als pde iv und tnf inhibitoren
GB9401460D0 (en) 1994-01-26 1994-03-23 Rhone Poulenc Rorer Ltd Compositions of matter
GB9507297D0 (en) 1995-04-07 1995-05-31 Rh Ne Poulenc Rorer Limited New composition of matter
US6196968B1 (en) 1997-06-02 2001-03-06 General Surgical Innovations, Inc. Direct vision subcutaneous tissue retractor and method for use
US6177077B1 (en) * 1999-02-24 2001-01-23 Edward L. Tobinick TNT inhibitors for the treatment of neurological disorders
WO2001047915A1 (en) 1999-12-23 2001-07-05 Icos Corporation Cyclic amp-specific phosphodiesterase inhibitors
HUP0600103A2 (en) 2001-03-02 2006-06-28 Bristol Myers Squibb Co Co-administration of melanocortin receptor agonist and phosphodiesterase inhibitor for treatment of cyclic-amp associated disorders
WO2004005258A1 (en) 2002-07-02 2004-01-15 Merck Frosst Canada & Co. Di-aryl-substituted-ethane pyridone pde4 inhibitors
US20060083714A1 (en) 2003-01-27 2006-04-20 Warner James M Combination of a pde iv inhibitor and a tnf-alpha antagonist
JP2007525482A (ja) * 2003-10-07 2007-09-06 レノビス， インコーポレイテッド イオンチャネルリガンドとしてのアミド化合物およびその使用
AU2006257863A1 (en) * 2005-06-10 2006-12-21 F. Hoffmann-La Roche Ag Trisubstituted amines as phosphodiesterase 4 inhibitors
US20070021451A1 (en) * 2005-07-20 2007-01-25 Hamamatsu University School Of Medicine Method for preventing or treating neurologic damage after spinal cord injury

Also Published As

Publication number Publication date
US8592443B2 (en) 2013-11-26
JO2662B1 (en) 2012-06-17
MA31369B1 (fr) 2010-05-03
CY1111779T1 (el) 2015-10-07
DE602008005873D1 (de) 2011-05-12
JP2010524905A (ja) 2010-07-22
DK2150253T3 (da) 2011-07-25
EA200970969A1 (ru) 2010-02-26
MY146657A (en) 2012-09-14
PL2150253T3 (pl) 2011-08-31
KR101470043B1 (ko) 2014-12-05
CN101674829A (zh) 2010-03-17
US20100137370A1 (en) 2010-06-03
EP2150253B1 (fr) 2011-03-30
HK1142000A1 (es) 2010-11-26
ES2363056T3 (es) 2011-07-19
TW200911248A (en) 2009-03-16
KR20090130063A (ko) 2009-12-17
CN101674829B (zh) 2012-01-18
CA2684172C (fr) 2015-10-27
CL2008001134A1 (es) 2009-01-16
JP5386477B2 (ja) 2014-01-15
IL201451A (en) 2013-04-30
PT2150253E (pt) 2011-06-17
CA2684172A1 (fr) 2008-12-04
AR066106A1 (es) 2009-07-22
BRPI0810446A2 (pt) 2014-10-14
HRP20110459T1 (hr) 2011-07-31
NZ580483A (en) 2011-06-30
AU2008257321B2 (en) 2013-08-15
ME00934B (me) 2012-06-20
UY31033A1 (es) 2008-11-28
WO2008145840A3 (fr) 2009-06-25
WO2008145840A2 (fr) 2008-12-04
PA8776601A1 (es) 2008-11-19
SI2150253T1 (sl) 2011-07-29
AU2008257321A1 (en) 2008-12-04
TWI411435B (zh) 2013-10-11
IL201451A0 (en) 2010-05-31
EA015355B1 (ru) 2011-06-30
FR2915098B1 (fr) 2009-06-05
ATE503481T1 (de) 2011-04-15
FR2915098A1 (fr) 2008-10-24
EP2150253A2 (fr) 2010-02-10

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