PT1982132T - Método de liofilização - Google Patents

Método de liofilização

Info

Publication number
PT1982132T
PT1982132T PT77501492T PT07750149T PT1982132T PT 1982132 T PT1982132 T PT 1982132T PT 77501492 T PT77501492 T PT 77501492T PT 07750149 T PT07750149 T PT 07750149T PT 1982132 T PT1982132 T PT 1982132T
Authority
PT
Portugal
Prior art keywords
lyophilization method
lyophilization
Prior art date
Application number
PT77501492T
Other languages
English (en)
Inventor
Hall Gasteyer Theodore
Rex Sever Robert
Hunek Balazs
Grinter Nigel
Lee Verdone Melinda
Original Assignee
Sp Ind Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sp Ind Inc filed Critical Sp Ind Inc
Publication of PT1982132T publication Critical patent/PT1982132T/pt

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Drying Of Solid Materials (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT77501492T 2006-02-10 2007-02-07 Método de liofilização PT1982132T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77186806P 2006-02-10 2006-02-10
US11/702,479 US8793895B2 (en) 2006-02-10 2007-02-05 Lyophilization system and method

Publications (1)

Publication Number Publication Date
PT1982132T true PT1982132T (pt) 2016-11-16

Family

ID=38366837

Family Applications (2)

Application Number Title Priority Date Filing Date
PT161763941T PT3136030T (pt) 2006-02-10 2007-02-07 Método de liofilização.
PT77501492T PT1982132T (pt) 2006-02-10 2007-02-07 Método de liofilização

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT161763941T PT3136030T (pt) 2006-02-10 2007-02-07 Método de liofilização.

Country Status (15)

Country Link
US (3) US8793895B2 (pt)
EP (3) EP1982132B1 (pt)
JP (1) JP5090374B2 (pt)
KR (1) KR101265381B1 (pt)
AU (1) AU2007215418B2 (pt)
BR (2) BRPI0706768B1 (pt)
CA (1) CA2640590C (pt)
DK (2) DK1982132T3 (pt)
ES (2) ES2748911T3 (pt)
HU (2) HUE047058T2 (pt)
IL (1) IL192544A (pt)
NO (1) NO20083548L (pt)
PT (2) PT3136030T (pt)
SI (2) SI1982132T1 (pt)
WO (1) WO2007095033A2 (pt)

Families Citing this family (50)

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US8793895B2 (en) * 2006-02-10 2014-08-05 Praxair Technology, Inc. Lyophilization system and method
EP1870649A1 (en) * 2006-06-20 2007-12-26 Octapharma AG Lyophilisation targetting defined residual moisture by limited desorption energy levels
US8015841B2 (en) 2006-09-08 2011-09-13 Praxair Technology, Inc. Cryogenic refrigeration system for lyophilization
US8240065B2 (en) * 2007-02-05 2012-08-14 Praxair Technology, Inc. Freeze-dryer and method of controlling the same
CN102149813B (zh) * 2008-09-12 2015-05-27 能波公司 利用冷冻和微波使生物材料脱水的设备和方法
US20110179667A1 (en) * 2009-09-17 2011-07-28 Lee Ron C Freeze drying system
US8966782B2 (en) 2010-09-28 2015-03-03 Baxter International Inc. Optimization of nucleation and crystallization for lyophilization using gap freezing
CN103140731B (zh) 2010-09-28 2015-12-16 巴克斯特国际公司 使用间隙冷冻来优化冻干的成核和结晶
US8549768B2 (en) 2011-03-11 2013-10-08 Linde Aktiengesellschaft Methods for freeze drying
CN104081142B (zh) * 2011-03-28 2017-03-01 普莱克斯技术有限公司 生物制药的散装冻结
US8839528B2 (en) * 2011-04-29 2014-09-23 Millrock Technology, Inc. Controlled nucleation during freezing step of freeze drying cycle using pressure differential ice fog distribution
JP2013055230A (ja) * 2011-09-05 2013-03-21 Toshiba Corp 半導体基板の超臨界乾燥方法
FR2990269B1 (fr) * 2012-05-02 2018-06-29 L'air Liquide,Societe Anonyme Pour L'etude Et L'exploitation Des Procedes Georges Claude Procede de lyophilisation
JP5827178B2 (ja) * 2012-06-05 2015-12-02 北越紀州製紙株式会社 セルロース多孔質体及びその製造方法
US8875413B2 (en) * 2012-08-13 2014-11-04 Millrock Technology, Inc. Controlled nucleation during freezing step of freeze drying cycle using pressure differential ice crystals distribution from condensed frost
DE102012021655B4 (de) 2012-11-03 2023-03-30 Hof Sonderanlagenbau Gmbh Verfahren zur Gefriertrocknung eines mit einem Lösungsmittel versehenen, feuchten Produktes
CA2941929C (en) 2013-03-15 2021-02-23 Truckee Applied Genomics, Llc Methods and reagents for maintaining the viability of cancer cells in surgically removed tissue
JP6173495B2 (ja) * 2013-05-29 2017-08-02 ゲア・プロセス・エンジニアリング・アクティーゼルスカブ トロリに収容されたトレイ内の製品の直列滅菌凍結乾燥を実現する方法、方法を実施するためのシステム、および方法の使用
US9121637B2 (en) * 2013-06-25 2015-09-01 Millrock Technology Inc. Using surface heat flux measurement to monitor and control a freeze drying process
US20160228371A1 (en) * 2013-10-18 2016-08-11 Abbvie Inc. Stable solid units and methods of making the same
WO2015077717A1 (en) 2013-11-25 2015-05-28 The Broad Institute Inc. Compositions and methods for diagnosing, evaluating and treating cancer by means of the dna methylation status
US11725237B2 (en) 2013-12-05 2023-08-15 The Broad Institute Inc. Polymorphic gene typing and somatic change detection using sequencing data
CA2932798C (en) * 2013-12-06 2022-09-20 The Broad Institute, Inc. Formulations for neoplasia vaccines
EP3082853A2 (en) 2013-12-20 2016-10-26 The Broad Institute, Inc. Combination therapy with neoantigen vaccine
CN112979828A (zh) 2014-07-17 2021-06-18 恺兴生命科技(上海)有限公司 靶向cld18a2的t淋巴细胞及其制备方法和应用
EP3234193B1 (en) 2014-12-19 2020-07-15 Massachusetts Institute of Technology Molecular biomarkers for cancer immunotherapy
US10993997B2 (en) 2014-12-19 2021-05-04 The Broad Institute, Inc. Methods for profiling the t cell repertoire
JP5847919B1 (ja) * 2014-12-26 2016-01-27 共和真空技術株式会社 凍結乾燥装置の凍結乾燥方法
KR102427458B1 (ko) 2015-05-19 2022-08-01 메디칸(주) 동결건조 방법 및 장치
EP3297660A2 (en) 2015-05-20 2018-03-28 The Broad Institute Inc. Shared neoantigens
US10605527B2 (en) 2015-09-22 2020-03-31 Millrock Technology, Inc. Apparatus and method for developing freeze drying protocols using small batches of product
JP6665063B2 (ja) * 2015-11-24 2020-03-13 株式会社西部技研 乾燥装置
JP6446604B2 (ja) * 2016-09-08 2018-12-26 アトナープ株式会社 事前分離ユニットを有するシステム
US10113797B2 (en) 2016-09-09 2018-10-30 Sp Industries, Inc. Energy recovery in a freeze-drying system
JP2019533995A (ja) 2016-10-05 2019-11-28 ゾエティス・サービシーズ・エルエルシー 強力な生ワクチンとして使用するための安定に脱水された原生動物を提供する凍結乾燥方法
US11549149B2 (en) 2017-01-24 2023-01-10 The Broad Institute, Inc. Compositions and methods for detecting a mutant variant of a polynucleotide
CA3069444A1 (en) * 2017-07-11 2019-01-17 Universal Stabilization Technologies, Inc. Method for preserving biopharmaceuticals
GB2564481B (en) 2017-07-14 2019-10-23 4D Pharma Leon S L U Process
WO2019199710A1 (en) * 2018-04-10 2019-10-17 Ima Life North America Inc. Freeze drying process and equipment health monitoring
US11828535B2 (en) 2018-06-29 2023-11-28 Universiteit Gent Freezing, drying and/or freeze-drying of product dose units
LT3856151T (lt) * 2018-09-26 2023-11-27 Medac Gesellschaft für klinische Spezialpräparate mbH Treosulfano liofilizatas
US11744257B1 (en) 2018-10-19 2023-09-05 Harvest Right, LLC Freeze-drying methods including vacuum freezing
US10676797B1 (en) * 2019-01-27 2020-06-09 Vinamit Usa Llc Concentrated sugarcane juice powder and method for preparing the same using the convection current freeze drying apparatus
US10966439B2 (en) * 2019-01-27 2021-04-06 Vinamit Usa Llc Concentrated fruit juice powder and method for preparing the same using a non-linear screw press juicer and convection current freeze drying apparatus
US10921058B2 (en) * 2019-01-27 2021-02-16 Vinamit Usa Llc Fully automatic convection current vacuum freeze drying method
JP6667884B1 (ja) * 2019-07-17 2020-03-18 株式会社松井製作所 粉粒体材料の乾燥装置及び粉粒体材料の乾燥方法
CN111346253B (zh) * 2020-03-10 2022-04-08 西安培华学院 一种水溶性多层生物材料的制备方法
US11287185B1 (en) 2020-09-09 2022-03-29 Stay Fresh Technology, LLC Freeze drying with constant-pressure and constant-temperature phases
WO2022175999A1 (ja) * 2021-02-16 2022-08-25 株式会社アルバック 凍結乾燥装置、および凍結乾燥方法
US12085337B2 (en) * 2021-10-20 2024-09-10 DSM Sales & Manufacturing, Inc. Freeze-drying systems and methods

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US4597188A (en) 1985-03-04 1986-07-01 Trappler Edward H Freeze dry process and structure
JPH05277302A (ja) * 1992-04-02 1993-10-26 Japan Steel Works Ltd:The 高水分材料の凍結濃縮方法及び装置
AU680727B2 (en) 1994-02-09 1997-08-07 Kinerton Limited Process for drying a material from solution
US5937656A (en) 1997-05-07 1999-08-17 Praxair Technology, Inc. Nonfreezing heat exchanger
US5966966A (en) 1997-05-21 1999-10-19 Trustees Of Tufts College Process and system for freeze concentration using ultrasonic nucleation useful in effluent processing
JP3050533B2 (ja) * 1997-06-10 2000-06-12 京都府 殺菌方法および殺菌装置
DE19751031A1 (de) 1997-11-19 1999-06-24 Ingo Dipl Ing Heschel Verfahren zur Herstellung poröser Strukturen
US6270723B1 (en) * 1998-06-15 2001-08-07 Bbi Bioseq, Inc. Rapid cryobaric sterilization and vaccine preparation
US6696019B2 (en) * 1998-06-15 2004-02-24 Bbi Bioseq, Inc. Rapid cryobaric sterilization and vaccine preparation
DE19936281C2 (de) 1999-08-02 2002-04-04 Bayer Ag Verfahren zur Gefriertrocknung
US6630185B2 (en) 2000-07-18 2003-10-07 Lipton, Division Of Conopco, Inc. Crystallization process using ultrasound
JP4104391B2 (ja) 2001-08-10 2008-06-18 カルソニックコンプレッサー株式会社 気体圧縮機
CA2849556A1 (en) * 2002-04-11 2003-10-23 Vu Truong-Le Preservation of bioactive materials by freeze dried foam
JP3869297B2 (ja) * 2002-04-16 2007-01-17 共和真空技術株式会社 凍結乾燥機における棚段の温度制御装置
GB0308360D0 (en) 2003-04-11 2003-05-14 Acton Elizabeth Improved method of freeze drying
JP2005060378A (ja) * 2003-07-28 2005-03-10 Yamanouchi Pharmaceut Co Ltd 生理活性蛋白質含有凍結乾燥製剤
US7229603B2 (en) 2004-06-17 2007-06-12 Anazaohealth Corporation Stablilized and lyophilized radiopharmaceutical agents
US9453675B2 (en) * 2006-02-10 2016-09-27 Sp Industries, Inc. Method of inducing nucleation of a material
US8793895B2 (en) * 2006-02-10 2014-08-05 Praxair Technology, Inc. Lyophilization system and method

Also Published As

Publication number Publication date
EP1982132B1 (en) 2016-08-10
US20140325868A1 (en) 2014-11-06
US20070186437A1 (en) 2007-08-16
CA2640590A1 (en) 2007-08-23
HUE031810T2 (en) 2017-08-28
US8793895B2 (en) 2014-08-05
IL192544A (en) 2012-07-31
US9651305B2 (en) 2017-05-16
ES2748911T3 (es) 2020-03-18
EP3136030A1 (en) 2017-03-01
PT3136030T (pt) 2019-10-25
JP2009526199A (ja) 2009-07-16
BR122019027321B1 (pt) 2021-03-23
AU2007215418B2 (en) 2011-02-10
SI1982132T1 (sl) 2017-01-31
HUE047058T2 (hu) 2020-04-28
AU2007215418A1 (en) 2007-08-23
DK1982132T3 (en) 2016-12-05
US20160169579A1 (en) 2016-06-16
EP3136030B1 (en) 2019-09-18
BRPI0706768A2 (pt) 2011-04-05
BRPI0706768B1 (pt) 2020-11-17
ES2602501T3 (es) 2017-02-21
SI3136030T1 (sl) 2020-02-28
IL192544A0 (en) 2009-02-11
EP1982132A2 (en) 2008-10-22
JP5090374B2 (ja) 2012-12-05
US9200836B2 (en) 2015-12-01
KR20080106509A (ko) 2008-12-08
EP3567328A1 (en) 2019-11-13
CA2640590C (en) 2013-08-06
KR101265381B1 (ko) 2013-05-20
WO2007095033A3 (en) 2007-11-22
NO20083548L (no) 2008-10-31
DK3136030T3 (da) 2019-10-14
WO2007095033A2 (en) 2007-08-23

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