PT1982132T - Método de liofilização - Google Patents

Método de liofilização

Info

Publication number
PT1982132T
PT1982132T PT77501492T PT07750149T PT1982132T PT 1982132 T PT1982132 T PT 1982132T PT 77501492 T PT77501492 T PT 77501492T PT 07750149 T PT07750149 T PT 07750149T PT 1982132 T PT1982132 T PT 1982132T
Authority
PT
Portugal
Prior art keywords
lyophilization method
lyophilization
Prior art date
Application number
PT77501492T
Other languages
English (en)
Inventor
Hall Gasteyer Theodore
Rex Sever Robert
Hunek Balazs
Grinter Nigel
Lee Verdone Melinda
Original Assignee
Sp Ind Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sp Ind Inc filed Critical Sp Ind Inc
Publication of PT1982132T publication Critical patent/PT1982132T/pt

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Drying Of Solid Materials (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT77501492T 2006-02-10 2007-02-07 Método de liofilização PT1982132T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77186806P 2006-02-10 2006-02-10
US11/702,479 US8793895B2 (en) 2006-02-10 2007-02-05 Lyophilization system and method

Publications (1)

Publication Number Publication Date
PT1982132T true PT1982132T (pt) 2016-11-16

Family

ID=38366837

Family Applications (2)

Application Number Title Priority Date Filing Date
PT161763941T PT3136030T (pt) 2006-02-10 2007-02-07 Método de liofilização.
PT77501492T PT1982132T (pt) 2006-02-10 2007-02-07 Método de liofilização

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT161763941T PT3136030T (pt) 2006-02-10 2007-02-07 Método de liofilização.

Country Status (15)

Country Link
US (3) US8793895B2 (pt)
EP (3) EP3136030B1 (pt)
JP (1) JP5090374B2 (pt)
KR (1) KR101265381B1 (pt)
AU (1) AU2007215418B2 (pt)
BR (2) BRPI0706768B1 (pt)
CA (1) CA2640590C (pt)
DK (2) DK3136030T3 (pt)
ES (2) ES2602501T3 (pt)
HU (2) HUE031810T2 (pt)
IL (1) IL192544A (pt)
NO (1) NO20083548L (pt)
PT (2) PT3136030T (pt)
SI (2) SI1982132T1 (pt)
WO (1) WO2007095033A2 (pt)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8793895B2 (en) * 2006-02-10 2014-08-05 Praxair Technology, Inc. Lyophilization system and method
EP1870649A1 (en) * 2006-06-20 2007-12-26 Octapharma AG Lyophilisation targetting defined residual moisture by limited desorption energy levels
US8015841B2 (en) 2006-09-08 2011-09-13 Praxair Technology, Inc. Cryogenic refrigeration system for lyophilization
US8240065B2 (en) * 2007-02-05 2012-08-14 Praxair Technology, Inc. Freeze-dryer and method of controlling the same
CA2736317C (en) 2008-09-12 2015-06-16 Enwave Corporation Apparatus and method for dehydrating biological materials with freezing and microwaving
US20110179667A1 (en) * 2009-09-17 2011-07-28 Lee Ron C Freeze drying system
US8966782B2 (en) * 2010-09-28 2015-03-03 Baxter International Inc. Optimization of nucleation and crystallization for lyophilization using gap freezing
CA2811428A1 (en) 2010-09-28 2012-04-26 Baxter International Inc. Optimization of nucleation and crystallization for lyophilization using gap freezing
US8549768B2 (en) 2011-03-11 2013-10-08 Linde Aktiengesellschaft Methods for freeze drying
EP2691719A4 (en) * 2011-03-28 2015-05-27 Praxair Technology Inc BULK CLEARANCE OF BIOPHARMACEUTICAL PRODUCTS
US8839528B2 (en) * 2011-04-29 2014-09-23 Millrock Technology, Inc. Controlled nucleation during freezing step of freeze drying cycle using pressure differential ice fog distribution
JP2013055230A (ja) * 2011-09-05 2013-03-21 Toshiba Corp 半導体基板の超臨界乾燥方法
FR2990269B1 (fr) * 2012-05-02 2018-06-29 L'air Liquide,Societe Anonyme Pour L'etude Et L'exploitation Des Procedes Georges Claude Procede de lyophilisation
JP5827178B2 (ja) * 2012-06-05 2015-12-02 北越紀州製紙株式会社 セルロース多孔質体及びその製造方法
US8875413B2 (en) * 2012-08-13 2014-11-04 Millrock Technology, Inc. Controlled nucleation during freezing step of freeze drying cycle using pressure differential ice crystals distribution from condensed frost
DE102012021655B4 (de) 2012-11-03 2023-03-30 Hof Sonderanlagenbau Gmbh Verfahren zur Gefriertrocknung eines mit einem Lösungsmittel versehenen, feuchten Produktes
SI2970878T1 (sl) * 2013-03-15 2019-02-28 Truckee Applied Genomics, Llc Postopki in reagenti za vzdrževanje preživetja rakavih celic v kirurško odstranjenem tkivu
EP3004767B1 (en) * 2013-05-29 2017-12-06 GEA Process Engineering A/S Method of providing inline sterile freeze drying of a product in trays accommodated in a trolley, system for carrying out the method, and use of the method
US9121637B2 (en) * 2013-06-25 2015-09-01 Millrock Technology Inc. Using surface heat flux measurement to monitor and control a freeze drying process
US20160228371A1 (en) * 2013-10-18 2016-08-11 Abbvie Inc. Stable solid units and methods of making the same
WO2015077717A1 (en) 2013-11-25 2015-05-28 The Broad Institute Inc. Compositions and methods for diagnosing, evaluating and treating cancer by means of the dna methylation status
US11725237B2 (en) 2013-12-05 2023-08-15 The Broad Institute Inc. Polymorphic gene typing and somatic change detection using sequencing data
EP3076992B1 (en) * 2013-12-06 2022-04-06 The Broad Institute, Inc. Formulations for neoplasia vaccines
AU2014368898B2 (en) 2013-12-20 2020-06-11 Dana-Farber Cancer Institute, Inc. Combination therapy with neoantigen vaccine
CN105315375B (zh) 2014-07-17 2021-04-23 恺兴生命科技(上海)有限公司 靶向cld18a2的t淋巴细胞及其制备方法和应用
WO2016100975A1 (en) 2014-12-19 2016-06-23 Massachsetts Institute Ot Technology Molecular biomarkers for cancer immunotherapy
US10993997B2 (en) 2014-12-19 2021-05-04 The Broad Institute, Inc. Methods for profiling the t cell repertoire
JP5847919B1 (ja) * 2014-12-26 2016-01-27 共和真空技術株式会社 凍結乾燥装置の凍結乾燥方法
KR102427458B1 (ko) 2015-05-19 2022-08-01 메디칸(주) 동결건조 방법 및 장치
EP3297660A2 (en) 2015-05-20 2018-03-28 The Broad Institute Inc. Shared neoantigens
US10605527B2 (en) 2015-09-22 2020-03-31 Millrock Technology, Inc. Apparatus and method for developing freeze drying protocols using small batches of product
JP6665063B2 (ja) * 2015-11-24 2020-03-13 株式会社西部技研 乾燥装置
JP6446604B2 (ja) * 2016-09-08 2018-12-26 アトナープ株式会社 事前分離ユニットを有するシステム
US10113797B2 (en) 2016-09-09 2018-10-30 Sp Industries, Inc. Energy recovery in a freeze-drying system
CN109789097B (zh) 2016-10-05 2021-05-18 硕腾服务有限责任公司 提供用作强效活疫苗的稳定脱水的原生动物的冻干方法
US11549149B2 (en) 2017-01-24 2023-01-10 The Broad Institute, Inc. Compositions and methods for detecting a mutant variant of a polynucleotide
JP7198264B2 (ja) * 2017-07-11 2022-12-28 ユニバーサル スタビリゼイション テクノロジーズ，インコーポレイテッド バイオ医薬品を保存するための方法
GB2564481B (en) 2017-07-14 2019-10-23 4D Pharma Leon S L U Process
CN112005069B (zh) * 2018-04-10 2023-01-10 Ima生命北美股份有限公司 冷冻干燥处理和装备健康状况监测
US11828535B2 (en) 2018-06-29 2023-11-28 Universiteit Gent Freezing, drying and/or freeze-drying of product dose units
PT3856151T (pt) * 2018-09-26 2023-10-27 Medac Ges Fuer Klinische Spezialpraeparate Mbh Liofilizado de treossulfano
US11744257B1 (en) 2018-10-19 2023-09-05 Harvest Right, LLC Freeze-drying methods including vacuum freezing
US10966439B2 (en) * 2019-01-27 2021-04-06 Vinamit Usa Llc Concentrated fruit juice powder and method for preparing the same using a non-linear screw press juicer and convection current freeze drying apparatus
US10921058B2 (en) * 2019-01-27 2021-02-16 Vinamit Usa Llc Fully automatic convection current vacuum freeze drying method
US10676797B1 (en) * 2019-01-27 2020-06-09 Vinamit Usa Llc Concentrated sugarcane juice powder and method for preparing the same using the convection current freeze drying apparatus
JP6667884B1 (ja) * 2019-07-17 2020-03-18 株式会社松井製作所 粉粒体材料の乾燥装置及び粉粒体材料の乾燥方法
CN111346253B (zh) * 2020-03-10 2022-04-08 西安培华学院 一种水溶性多层生物材料的制备方法
US11287185B1 (en) 2020-09-09 2022-03-29 Stay Fresh Technology, LLC Freeze drying with constant-pressure and constant-temperature phases
WO2022175999A1 (ja) * 2021-02-16 2022-08-25 株式会社アルバック 凍結乾燥装置、および凍結乾燥方法
US12085337B2 (en) * 2021-10-20 2024-09-10 DSM Sales & Manufacturing, Inc. Freeze-drying systems and methods

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4590684A (en) 1984-11-20 1986-05-27 Eden Research Laboratories, Inc. Continuous freeze drying
US4597188A (en) 1985-03-04 1986-07-01 Trappler Edward H Freeze dry process and structure
JPH05277302A (ja) * 1992-04-02 1993-10-26 Japan Steel Works Ltd:The 高水分材料の凍結濃縮方法及び装置
WO1995022036A1 (en) 1994-02-09 1995-08-17 Kinerton Limited Process for drying a material from solution
US5937656A (en) 1997-05-07 1999-08-17 Praxair Technology, Inc. Nonfreezing heat exchanger
US5966966A (en) 1997-05-21 1999-10-19 Trustees Of Tufts College Process and system for freeze concentration using ultrasonic nucleation useful in effluent processing
JP3050533B2 (ja) * 1997-06-10 2000-06-12 京都府 殺菌方法および殺菌装置
DE19751031A1 (de) 1997-11-19 1999-06-24 Ingo Dipl Ing Heschel Verfahren zur Herstellung poröser Strukturen
US6270723B1 (en) * 1998-06-15 2001-08-07 Bbi Bioseq, Inc. Rapid cryobaric sterilization and vaccine preparation
US6696019B2 (en) * 1998-06-15 2004-02-24 Bbi Bioseq, Inc. Rapid cryobaric sterilization and vaccine preparation
DE19936281C2 (de) * 1999-08-02 2002-04-04 Bayer Ag Verfahren zur Gefriertrocknung
US6630185B2 (en) 2000-07-18 2003-10-07 Lipton, Division Of Conopco, Inc. Crystallization process using ultrasound
JP4104391B2 (ja) 2001-08-10 2008-06-18 カルソニックコンプレッサー株式会社 気体圧縮機
EP2591771A1 (en) * 2002-04-11 2013-05-15 MedImmune, LLC Preservation of bioactive materials by freeze dried foam
JP3869297B2 (ja) * 2002-04-16 2007-01-17 共和真空技術株式会社 凍結乾燥機における棚段の温度制御装置
GB0308360D0 (en) 2003-04-11 2003-05-14 Acton Elizabeth Improved method of freeze drying
JP2005060378A (ja) * 2003-07-28 2005-03-10 Yamanouchi Pharmaceut Co Ltd 生理活性蛋白質含有凍結乾燥製剤
US7229603B2 (en) 2004-06-17 2007-06-12 Anazaohealth Corporation Stablilized and lyophilized radiopharmaceutical agents
US8793895B2 (en) * 2006-02-10 2014-08-05 Praxair Technology, Inc. Lyophilization system and method
US9453675B2 (en) * 2006-02-10 2016-09-27 Sp Industries, Inc. Method of inducing nucleation of a material

Also Published As

Publication number Publication date
EP3136030A1 (en) 2017-03-01
US20160169579A1 (en) 2016-06-16
US8793895B2 (en) 2014-08-05
SI3136030T1 (sl) 2020-02-28
WO2007095033A2 (en) 2007-08-23
BRPI0706768A2 (pt) 2011-04-05
US20070186437A1 (en) 2007-08-16
JP2009526199A (ja) 2009-07-16
EP1982132A2 (en) 2008-10-22
BR122019027321B1 (pt) 2021-03-23
ES2748911T3 (es) 2020-03-18
WO2007095033A3 (en) 2007-11-22
DK1982132T3 (en) 2016-12-05
CA2640590C (en) 2013-08-06
BRPI0706768B1 (pt) 2020-11-17
SI1982132T1 (sl) 2017-01-31
DK3136030T3 (da) 2019-10-14
EP1982132B1 (en) 2016-08-10
IL192544A0 (en) 2009-02-11
HUE031810T2 (en) 2017-08-28
JP5090374B2 (ja) 2012-12-05
IL192544A (en) 2012-07-31
US9200836B2 (en) 2015-12-01
US9651305B2 (en) 2017-05-16
EP3567328A1 (en) 2019-11-13
ES2602501T3 (es) 2017-02-21
KR20080106509A (ko) 2008-12-08
AU2007215418A1 (en) 2007-08-23
US20140325868A1 (en) 2014-11-06
HUE047058T2 (hu) 2020-04-28
EP3136030B1 (en) 2019-09-18
PT3136030T (pt) 2019-10-25
NO20083548L (no) 2008-10-31
KR101265381B1 (ko) 2013-05-20
CA2640590A1 (en) 2007-08-23
AU2007215418B2 (en) 2011-02-10

Similar Documents

Publication Publication Date Title
SI3136030T1 (sl) Postopek liofilizacije
GB0601961D0 (en) Method
GB0603081D0 (en) Method
GB0607317D0 (en) Method
GB0606147D0 (en) Method
GB0618001D0 (en) Method
GB0605323D0 (en) Method
GB0603008D0 (en) Method
GB0604018D0 (en) Method
GB0601699D0 (en) Method
GB0602986D0 (en) Method
GB0618046D0 (en) Method
GB0622580D0 (en) Method
GB0606954D0 (en) Method
GB0625782D0 (en) Method
GB0618656D0 (en) Method
GB0612342D0 (en) Method
GB0612014D0 (en) Method
GB0610949D0 (en) Method
GB0617274D0 (en) Method
GB0610338D0 (en) Method
GB0609901D0 (en) Method
GB0602830D0 (en) Method
GB0600324D0 (en) Method
GB0603505D0 (en) Method