PT1948180E - Tratamento de combinação de cancro compreendendo inibidores de egfr/her2 - Google Patents

Tratamento de combinação de cancro compreendendo inibidores de egfr/her2 Download PDF

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Publication number
PT1948180E
PT1948180E PT68193804T PT06819380T PT1948180E PT 1948180 E PT1948180 E PT 1948180E PT 68193804 T PT68193804 T PT 68193804T PT 06819380 T PT06819380 T PT 06819380T PT 1948180 E PT1948180 E PT 1948180E
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PT
Portugal
Prior art keywords
cancers
amino
mutation
treatment
carcinoma
Prior art date
Application number
PT68193804T
Other languages
English (en)
Portuguese (pt)
Inventor
Flavio Solca
Anke Baum
Andree Amelsberg
Gerd Stehle
Jacobus C A Van Meel
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of PT1948180E publication Critical patent/PT1948180E/pt

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT68193804T 2005-11-11 2006-11-09 Tratamento de combinação de cancro compreendendo inibidores de egfr/her2 PT1948180E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05110669 2005-11-11

Publications (1)

Publication Number Publication Date
PT1948180E true PT1948180E (pt) 2013-05-10

Family

ID=37658836

Family Applications (1)

Application Number Title Priority Date Filing Date
PT68193804T PT1948180E (pt) 2005-11-11 2006-11-09 Tratamento de combinação de cancro compreendendo inibidores de egfr/her2

Country Status (11)

Country Link
US (3) US20090306101A1 (OSRAM)
EP (2) EP1948180B1 (OSRAM)
JP (1) JP2009515852A (OSRAM)
CA (1) CA2629249C (OSRAM)
CY (1) CY1114040T1 (OSRAM)
DK (1) DK1948180T3 (OSRAM)
ES (1) ES2412879T3 (OSRAM)
PL (1) PL1948180T3 (OSRAM)
PT (1) PT1948180E (OSRAM)
SI (1) SI1948180T1 (OSRAM)
WO (1) WO2007054551A1 (OSRAM)

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Also Published As

Publication number Publication date
EP2340837A1 (en) 2011-07-06
US20180086744A1 (en) 2018-03-29
WO2007054551A1 (en) 2007-05-18
ES2412879T3 (es) 2013-07-12
PL1948180T3 (pl) 2013-09-30
CA2629249C (en) 2015-05-05
CY1114040T1 (el) 2016-07-27
EP1948180A1 (en) 2008-07-30
EP2340837B1 (en) 2017-03-15
US20090306101A1 (en) 2009-12-10
CA2629249A1 (en) 2007-05-18
US20140199298A1 (en) 2014-07-17
SI1948180T1 (sl) 2013-06-28
DK1948180T3 (da) 2013-05-27
JP2009515852A (ja) 2009-04-16
EP1948180B1 (en) 2013-03-13

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