CY1114040T1 - Συνδυαστικη θεραπεια του καρκινου περιλαμβανουσα αναστολεις των egfr/her2 - Google Patents

Συνδυαστικη θεραπεια του καρκινου περιλαμβανουσα αναστολεις των egfr/her2

Info

Publication number
CY1114040T1
CY1114040T1 CY20131100455T CY131100455T CY1114040T1 CY 1114040 T1 CY1114040 T1 CY 1114040T1 CY 20131100455 T CY20131100455 T CY 20131100455T CY 131100455 T CY131100455 T CY 131100455T CY 1114040 T1 CY1114040 T1 CY 1114040T1
Authority
CY
Cyprus
Prior art keywords
cancer
treatment
treatment including
her2 inhibitors
including egfr
Prior art date
Application number
CY20131100455T
Other languages
English (en)
Inventor
Flavio Solca
Andree Amelsberg
Gerd Stehle
Meel Jacobus C A Van
Anke Baum
Original Assignee
Boehringer Ingelheim International Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International Gmbh filed Critical Boehringer Ingelheim International Gmbh
Publication of CY1114040T1 publication Critical patent/CY1114040T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Η εφεύρεση αναφέρεται σε μια θεραπεία του καρκίνου περιλαμβάνουσα τη συγχορήγηση σε ένα άτομο που χρήζει μιας τέτοιας θεραπείας ή/και τη συν-θεραπεία ενός ατόμου που χρήζει μιας τέτοιας θεραπείας με αποτελεσματικές ποσότητες από: (1) μια ένωση 1 του τύπου (1), όπου οι ομάδες Ra και Rd έχουν τις έννοιες που παρέχονται στις αξιώσεις και την προδιαγραφή· και (2) τουλάχιστον έναν περαιτέρω χημειοθεραπευτικό παράγοντα 2∙ προαιρετικώς σε συνδυασμό με ακτινοθεραπεία, ακτινο-ανοσοθεραπεία ή/και εκτομή όγκου με χειρουργική επέμβαση, περαιτέρω, η εφεύρεση αναφέρεται σε αντίστοιχα φάρμακα και στην παρασκευή αυτών.
CY20131100455T 2005-11-11 2013-06-07 Συνδυαστικη θεραπεια του καρκινου περιλαμβανουσα αναστολεις των egfr/her2 CY1114040T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05110669 2005-11-11
EP06819380A EP1948180B1 (en) 2005-11-11 2006-11-09 Combination treatment of cancer comprising egfr/her2 inhibitors

Publications (1)

Publication Number Publication Date
CY1114040T1 true CY1114040T1 (el) 2016-07-27

Family

ID=37658836

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20131100455T CY1114040T1 (el) 2005-11-11 2013-06-07 Συνδυαστικη θεραπεια του καρκινου περιλαμβανουσα αναστολεις των egfr/her2

Country Status (11)

Country Link
US (3) US20090306101A1 (el)
EP (2) EP1948180B1 (el)
JP (1) JP2009515852A (el)
CA (1) CA2629249C (el)
CY (1) CY1114040T1 (el)
DK (1) DK1948180T3 (el)
ES (1) ES2412879T3 (el)
PL (1) PL1948180T3 (el)
PT (1) PT1948180E (el)
SI (1) SI1948180T1 (el)
WO (1) WO2007054551A1 (el)

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Also Published As

Publication number Publication date
US20180086744A1 (en) 2018-03-29
EP1948180B1 (en) 2013-03-13
ES2412879T3 (es) 2013-07-12
SI1948180T1 (sl) 2013-06-28
US20090306101A1 (en) 2009-12-10
CA2629249C (en) 2015-05-05
CA2629249A1 (en) 2007-05-18
PT1948180E (pt) 2013-05-10
EP2340837B1 (en) 2017-03-15
US20140199298A1 (en) 2014-07-17
JP2009515852A (ja) 2009-04-16
PL1948180T3 (pl) 2013-09-30
WO2007054551A1 (en) 2007-05-18
DK1948180T3 (da) 2013-05-27
EP2340837A1 (en) 2011-07-06
EP1948180A1 (en) 2008-07-30

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