PT1777236T - Sacáridos modificados possuindo estabilidade melhorada em água para utilização como um medicamento - Google Patents

Sacáridos modificados possuindo estabilidade melhorada em água para utilização como um medicamento

Info

Publication number
PT1777236T
PT1777236T PT60768538T PT06076853T PT1777236T PT 1777236 T PT1777236 T PT 1777236T PT 60768538 T PT60768538 T PT 60768538T PT 06076853 T PT06076853 T PT 06076853T PT 1777236 T PT1777236 T PT 1777236T
Authority
PT
Portugal
Prior art keywords
improved stability
medicament
water
modified
modified saccharides
Prior art date
Application number
PT60768538T
Other languages
English (en)
Portuguese (pt)
Inventor
Norelli Francesco
Costantino Paolo
Berti Francesco
Bartoloni Antonella
Original Assignee
Glaxosmithkline Biologicals Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0207117A external-priority patent/GB0207117D0/en
Priority claimed from GB0220195A external-priority patent/GB0220195D0/en
Priority claimed from GB0229494A external-priority patent/GB0229494D0/en
Priority claimed from GB0230163A external-priority patent/GB0230163D0/en
Application filed by Glaxosmithkline Biologicals Sa filed Critical Glaxosmithkline Biologicals Sa
Publication of PT1777236T publication Critical patent/PT1777236T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Polymers & Plastics (AREA)
  • Immunology (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
PT60768538T 2002-03-26 2003-03-26 Sacáridos modificados possuindo estabilidade melhorada em água para utilização como um medicamento PT1777236T (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0207117A GB0207117D0 (en) 2002-03-26 2002-03-26 Modified saccharides having improved stability in water
GB0220195A GB0220195D0 (en) 2002-08-30 2002-08-30 Modified saccharides having improved stability in water
GB0229494A GB0229494D0 (en) 2002-12-18 2002-12-18 Modified saccharides having improved stability in water
GB0230163A GB0230163D0 (en) 2002-12-24 2002-12-24 Modified saccharides having improved stability in water

Publications (1)

Publication Number Publication Date
PT1777236T true PT1777236T (pt) 2017-02-13

Family

ID=28457825

Family Applications (2)

Application Number Title Priority Date Filing Date
PT60768538T PT1777236T (pt) 2002-03-26 2003-03-26 Sacáridos modificados possuindo estabilidade melhorada em água para utilização como um medicamento
PT03712543T PT1490409E (pt) 2002-03-26 2003-03-26 Sacáridos modificados possuindo uma estabilidade melhorada em água

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT03712543T PT1490409E (pt) 2002-03-26 2003-03-26 Sacáridos modificados possuindo uma estabilidade melhorada em água

Country Status (14)

Country Link
EP (2) EP1777236B8 (cg-RX-API-DMAC7.html)
JP (2) JP2005526153A (cg-RX-API-DMAC7.html)
AT (1) ATE419278T1 (cg-RX-API-DMAC7.html)
BR (1) BR0308768A (cg-RX-API-DMAC7.html)
CA (1) CA2480389C (cg-RX-API-DMAC7.html)
CY (2) CY1108911T1 (cg-RX-API-DMAC7.html)
DE (1) DE60325565D1 (cg-RX-API-DMAC7.html)
DK (2) DK1777236T3 (cg-RX-API-DMAC7.html)
ES (2) ES2616180T3 (cg-RX-API-DMAC7.html)
HU (1) HUE030532T2 (cg-RX-API-DMAC7.html)
MX (1) MXPA04009339A (cg-RX-API-DMAC7.html)
NZ (1) NZ535968A (cg-RX-API-DMAC7.html)
PT (2) PT1777236T (cg-RX-API-DMAC7.html)
WO (1) WO2003080678A1 (cg-RX-API-DMAC7.html)

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EP3461496B1 (en) * 2009-06-22 2023-08-23 Wyeth LLC Compositions and methods for preparing staphylococcus aureus serotype 5 and 8 capsular polysaccharide conjugate immunogenic compositions
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CN102724988B (zh) 2009-09-30 2014-09-10 诺华股份有限公司 脑膜炎球菌fHBP多肽的表达
CA2779816A1 (en) 2009-10-27 2011-05-05 Novartis Ag Modified meningococcal fhbp polypeptides
WO2011161653A1 (en) 2010-06-25 2011-12-29 Novartis Ag Combinations of meningococcal factor h binding proteins
SI3246044T2 (sl) 2010-08-23 2024-06-28 Wyeth Llc Stabilne formulacije antigenov neisseria meningitidis RLP2086
US9057716B2 (en) 2010-09-04 2015-06-16 Novartis Ag Bactericidal antibody assays to assess immunogenicity and potency of meningococcal capsular saccharide vaccines
PE20140173A1 (es) 2010-09-10 2014-02-20 Wyeth Llc Variantes no lipidadas de antigenos orf2086 de neisseria meningitidis
BR112013022397A2 (pt) 2011-03-02 2017-09-26 Derek O’Hagan vacinas combinadas com doses menores de antígeno e/ou adjuvante
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Also Published As

Publication number Publication date
CA2480389A1 (en) 2003-10-02
HUE030532T2 (en) 2017-05-29
WO2003080678A1 (en) 2003-10-02
ES2616180T3 (es) 2017-06-09
EP1777236B1 (en) 2016-11-30
EP1490409B1 (en) 2008-12-31
EP1777236A1 (en) 2007-04-25
NZ535968A (en) 2006-08-31
EP1777236B8 (en) 2017-02-22
DE60325565D1 (de) 2009-02-12
ATE419278T1 (de) 2009-01-15
ES2318117T3 (es) 2009-05-01
CA2480389C (en) 2012-10-09
DK1777236T3 (en) 2017-02-27
BR0308768A (pt) 2005-02-15
PT1490409E (pt) 2009-04-03
AU2003216633A1 (en) 2003-10-08
EP1490409A1 (en) 2004-12-29
CY1118584T1 (el) 2017-07-12
JP2005526153A (ja) 2005-09-02
JP2010132925A (ja) 2010-06-17
DK1490409T3 (da) 2009-03-23
JP5361767B2 (ja) 2013-12-04
CY1108911T1 (el) 2014-07-02
MXPA04009339A (es) 2005-01-25

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