PT1770162E - Composições imunológicas para a modulação da miostatina em indivíduos vertebrados - Google Patents

Composições imunológicas para a modulação da miostatina em indivíduos vertebrados Download PDF

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Publication number
PT1770162E
PT1770162E PT06026306T PT06026306T PT1770162E PT 1770162 E PT1770162 E PT 1770162E PT 06026306 T PT06026306 T PT 06026306T PT 06026306 T PT06026306 T PT 06026306T PT 1770162 E PT1770162 E PT 1770162E
Authority
PT
Portugal
Prior art keywords
immunological compositions
vertebrate subjects
modulate myostatin
myostatin
modulate
Prior art date
Application number
PT06026306T
Other languages
English (en)
Portuguese (pt)
Inventor
Christopher A Barker
Mohamad Morsey
Original Assignee
Metamorphix International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metamorphix International Inc filed Critical Metamorphix International Inc
Publication of PT1770162E publication Critical patent/PT1770162E/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Obesity (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Transplantation (AREA)
  • Child & Adolescent Psychology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PT06026306T 1998-02-19 1999-02-19 Composições imunológicas para a modulação da miostatina em indivíduos vertebrados PT1770162E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7521398P 1998-02-19 1998-02-19

Publications (1)

Publication Number Publication Date
PT1770162E true PT1770162E (pt) 2009-03-24

Family

ID=22124285

Family Applications (2)

Application Number Title Priority Date Filing Date
PT99904660T PT1056845E (pt) 1998-02-19 1999-02-19 Composições imunologicas para modular a miostatina em vertebrados
PT06026306T PT1770162E (pt) 1998-02-19 1999-02-19 Composições imunológicas para a modulação da miostatina em indivíduos vertebrados

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT99904660T PT1056845E (pt) 1998-02-19 1999-02-19 Composições imunologicas para modular a miostatina em vertebrados

Country Status (18)

Country Link
US (2) US6369201B1 (ja)
EP (3) EP1770162B1 (ja)
JP (1) JP2002504326A (ja)
KR (1) KR20010041111A (ja)
AR (1) AR019818A1 (ja)
AT (2) ATE352619T1 (ja)
AU (1) AU765014B2 (ja)
BR (1) BR9907995A (ja)
CA (2) CA2687533C (ja)
CY (2) CY1108074T1 (ja)
DE (2) DE69940230D1 (ja)
DK (2) DK1770162T3 (ja)
ES (3) ES2527410T3 (ja)
IL (1) IL137831A0 (ja)
NZ (1) NZ506911A (ja)
PT (2) PT1056845E (ja)
WO (1) WO1999042573A1 (ja)
ZA (1) ZA991369B (ja)

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US7332575B2 (en) 1994-03-18 2008-02-19 The Johns Hopkins University School Of Medicine Growth differentiation factor-8 nucleic acid and polypeptide from aquatic species, and transgenic aquatic species
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US7320789B2 (en) * 2001-09-26 2008-01-22 Wyeth Antibody inhibitors of GDF-8 and uses thereof
CA2476654A1 (en) * 2002-02-21 2003-09-04 Wyeth Follistatin domain containing proteins
BR0307907A2 (pt) * 2002-02-21 2011-07-05 Wyeth Corp gasp1: proteìna contendo domìnio de folistatina
AU2003272394A1 (en) * 2002-09-16 2004-04-30 Wyeth Metalloprotease activation of myostatin, and methods of modulating myostatin activity
US7261893B2 (en) * 2002-10-22 2007-08-28 Wyeth Neutralizing antibodies against GDF-8 and uses therefor
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KR20130036378A (ko) * 2002-12-20 2013-04-11 암겐 인코포레이티드 미오스타틴을 저해하는 결합제
KR20060026860A (ko) 2003-06-02 2006-03-24 와이어쓰 신경근 장애의 치료를 위한, 코르티코스테로이드와 조합된미오스타틴 (ｇｄｆ８) 저해제의 용도
RU2422460C2 (ru) * 2003-12-31 2011-06-27 Шеринг-Плоу Лтд. Выделенный пептид, обладающий специфической связывающей анти-gdf-8 антитело активностью, выделенная молекула нуклеиновой кислоты, вектор экспрессии, клетка-хозяин, способ получения пептида, вакцинная композиция и способ вызывания иммунного ответа анти-gdf-8, способ скрининга для отбора анти-gdf-8 антитела и способ понижающего регулирования активности gdf-8 у животного
JP4688483B2 (ja) 2004-04-15 2011-05-25 株式会社テクノネットワーク四国 フォリスタチン変異体ポリペプチド
CN101001642A (zh) * 2004-08-12 2007-07-18 惠氏公司 使用gdf－8抑制剂对糖尿病、肥胖症和心血管病的联合治疗
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AR051853A1 (es) * 2004-12-30 2007-02-14 Schering Plough Ltd Vacuna para aumentar el crecimiento basada en epitopes neutralizantes
NZ538097A (en) * 2005-02-07 2006-07-28 Ovita Ltd Method and compositions for improving wound healing
US20060240488A1 (en) * 2005-03-23 2006-10-26 Nowak John A Detection of an immune response to GDF-8 modulating agents
CA2632544C (en) * 2005-12-06 2014-09-23 Amgen Inc. Use of myostatin antagonist for treating the effects of hypogonadism
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GB0715087D0 (en) 2007-08-03 2007-09-12 Summit Corp Plc Drug combinations for the treatment of duchenne muscular dystrophy
CN101678107A (zh) 2007-08-03 2010-03-24 萨米特公开有限公司 用于治疗杜兴型肌营养不良的药物组合物
KR100857861B1 (ko) * 2007-10-15 2008-09-11 주식회사 바이오리더스 Ｍｙｏ－２ 펩타이드 중합체와 마이오스타틴의 융합단백질표면발현용 벡터 및 상기 벡터로 형질전환된 미생물
PT2880053T (pt) 2012-08-01 2020-05-22 Ikaika Therapeutics Llc Mitigação de fibrose e danos de tecidos por anticorpo antiltbp4
CN104391628B (zh) * 2014-04-02 2018-02-23 贵阳朗玛信息技术股份有限公司 进程切换方法及装置
EP2960653A1 (en) * 2014-06-24 2015-12-30 Stichting Kwaliteitsgarantie Vleeskalversector Diagnostic kit and method for the identification of the manipulation of muscle mass in a domestic animal
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US20220062299A1 (en) 2018-12-26 2022-03-03 Northwestern University Use of glucocorticoid steroids in preventing and treating conditions of muscle wasting, aging and metabolic disorder
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Also Published As

Publication number Publication date
CY1108889T1 (el) 2014-07-02
ES2280115T3 (es) 2007-09-01
PT1056845E (pt) 2007-04-30
ATE352619T1 (de) 2007-02-15
CA2323607A1 (en) 1999-08-26
ES2527410T3 (es) 2015-01-23
ATE419353T1 (de) 2009-01-15
CA2323607C (en) 2009-12-22
AR019818A1 (es) 2002-03-20
EP2018871B1 (en) 2014-10-08
AU2507399A (en) 1999-09-06
NZ506911A (en) 2003-09-26
DE69934970T2 (de) 2007-10-25
US6369201B1 (en) 2002-04-09
EP1056845B1 (en) 2007-01-24
JP2002504326A (ja) 2002-02-12
CA2687533C (en) 2016-02-02
EP1770162B1 (en) 2008-12-31
EP2018871A1 (en) 2009-01-28
AU765014B2 (en) 2003-09-04
DK1770162T3 (da) 2009-04-14
ES2318654T3 (es) 2009-05-01
US20030065137A1 (en) 2003-04-03
ZA991369B (en) 1999-08-20
BR9907995A (pt) 2001-05-15
CA2687533A1 (en) 1999-08-26
EP1056845A1 (en) 2000-12-06
EP1770162A1 (en) 2007-04-04
WO1999042573A1 (en) 1999-08-26
DK1056845T3 (da) 2007-05-29
DE69940230D1 (de) 2009-02-12
KR20010041111A (ko) 2001-05-15
DE69934970D1 (de) 2007-03-15
IL137831A0 (en) 2001-10-31
CY1108074T1 (el) 2014-02-12

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