PT1727786E - Sais de adição ácida de ácido 5-aminolevulínico ou seus derivados - Google Patents

Sais de adição ácida de ácido 5-aminolevulínico ou seus derivados Download PDF

Info

Publication number
PT1727786E
PT1727786E PT05732530T PT05732530T PT1727786E PT 1727786 E PT1727786 E PT 1727786E PT 05732530 T PT05732530 T PT 05732530T PT 05732530 T PT05732530 T PT 05732530T PT 1727786 E PT1727786 E PT 1727786E
Authority
PT
Portugal
Prior art keywords
acid
derivatives
ala
aminolevulinic
addition salts
Prior art date
Application number
PT05732530T
Other languages
English (en)
Inventor
Jo Klaveness
Aslak Godal
Jon Erik Braenden
Nils Olav Nilsen
Original Assignee
Photocure Asa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Photocure Asa filed Critical Photocure Asa
Publication of PT1727786E publication Critical patent/PT1727786E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0061—5-aminolevulinic acid-based PDT: 5-ALA-PDT involving porphyrins or precursors of protoporphyrins generated in vivo from 5-ALA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
PT05732530T 2004-03-26 2005-03-29 Sais de adição ácida de ácido 5-aminolevulínico ou seus derivados PT1727786E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0406917.5A GB0406917D0 (en) 2004-03-26 2004-03-26 Compounds

Publications (1)

Publication Number Publication Date
PT1727786E true PT1727786E (pt) 2011-07-08

Family

ID=32188818

Family Applications (1)

Application Number Title Priority Date Filing Date
PT05732530T PT1727786E (pt) 2004-03-26 2005-03-29 Sais de adição ácida de ácido 5-aminolevulínico ou seus derivados

Country Status (15)

Country Link
US (2) US7888526B2 (pt)
EP (2) EP2308830B1 (pt)
JP (1) JP5164565B2 (pt)
CN (1) CN1938264B (pt)
AT (1) ATE514672T1 (pt)
AU (1) AU2005225616B2 (pt)
CA (1) CA2561050C (pt)
DK (1) DK1727786T3 (pt)
ES (2) ES2639021T3 (pt)
GB (1) GB0406917D0 (pt)
PL (1) PL1727786T3 (pt)
PT (1) PT1727786E (pt)
RU (1) RU2392266C2 (pt)
SI (1) SI1727786T1 (pt)
WO (1) WO2005092838A1 (pt)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4719483B2 (ja) * 2004-03-30 2011-07-06 コスモ石油株式会社 ５−アミノレブリン酸スルホン酸塩の製造方法
CA2562170C (en) 2004-03-30 2013-04-23 Cosmo Oil Co., Ltd. 5-aminolevulinic acid salt, process for producing the same and use thereof
GB0424833D0 (en) 2004-11-10 2004-12-15 Photocure Asa Method
JP4934292B2 (ja) * 2005-07-05 2012-05-16 コスモ石油株式会社 ５−アミノレブリン酸エステルリン酸類塩、その製造方法及びその用途
JP4934293B2 (ja) * 2005-07-05 2012-05-16 コスモ石油株式会社 植物活力剤組成物
US20070225518A1 (en) * 2006-03-22 2007-09-27 Zvi Malik 5-Aminolevulinic acid salts and their use
KR100796450B1 (ko) 2006-06-29 2008-01-22 전남대학교산학협력단 5-아미노레불린산의 불포화 알킬 에스터 및 약학적으로허용되는 그의 염, 이의 제조방법 및 이의 용도
JP4989153B2 (ja) 2006-08-15 2012-08-01 コスモ石油株式会社 ５−アミノレブリン酸リン酸塩の新規結晶及びその製造方法
GB0700580D0 (en) * 2007-01-11 2007-02-21 Photocure Asa Use
WO2008106966A1 (en) * 2007-03-06 2008-09-12 Christiansen Kaare A method for non-therapeutic or therapeutic photodynamic skin treatment
AU2009319998B2 (en) * 2008-10-30 2015-07-16 Archer Daniels Midland Company Reduction of HMF ethers with metal catalyst
GB0823472D0 (en) 2008-12-23 2009-01-28 Photocure Asa Product
GB0900461D0 (en) 2009-01-12 2009-02-11 Photocure Asa Photodynamic therapy device
NZ596943A (en) 2009-06-11 2013-09-27 Photocure Asa Semi-solid compositions and pharmaceutical products
CA2790827A1 (en) 2010-03-01 2011-09-09 Photocure Asa Cosmetic compositions
EP2394642A1 (en) 2010-06-10 2011-12-14 Universite De Geneve 5-ALA ester formulations and use thereof
EP2585111A1 (en) 2010-06-23 2013-05-01 Photocure ASA Hyperosmotic preparations comprising 5 -amino levulinic acid or derivative as photosensitizing agent
CA2804337A1 (en) 2010-07-09 2012-01-12 Photocure Asa Dry compositions and devices containing such dry compositions for use in photodynamic therapy or photodynamic diagnosis
US9645154B2 (en) 2010-12-24 2017-05-09 Arkray, Inc. Method for detecting cancer cell
EP2766049A1 (en) 2011-10-14 2014-08-20 Photocure ASA Photodynamic diagnosis of abnormalities of the epithelial lining of the oesophagus with the means of a 5-ala ester
US20140316534A1 (en) 2011-10-14 2014-10-23 Photocure Asa Stent
WO2013092505A1 (en) 2011-12-19 2013-06-27 Photocure Asa Irradiation apparatus
SG11201500805VA (en) 2012-08-03 2015-02-27 Photocure Asa Compounds
US9387341B2 (en) 2012-08-10 2016-07-12 Dusa Pharmaceuticals, Inc. Method for the treatment of acne
US20140067024A1 (en) 2012-08-30 2014-03-06 Photocure Asa Dual panel photodynamic therapy lamp
GB201221123D0 (en) 2012-11-23 2013-01-09 Photocure As Device for photodynamic treatment
GB201306369D0 (en) 2013-04-09 2013-05-22 Photocure As Irradiation device
WO2015091037A1 (en) 2013-12-20 2015-06-25 Galderma Research & Development Pulse photodynamic treatment of photodamaged skin
EP3095464A1 (en) 2015-05-19 2016-11-23 Universite De Geneve 5-ala derivatives and use thereof
KR20180094986A (ko) 2015-12-17 2018-08-24 포토큐어 에이에스에이 방광암에 대한 광역학 요법 (pdt)의 방법
GB201522311D0 (en) 2015-12-17 2016-02-03 Photocure Asa Use
GB201522309D0 (en) 2015-12-17 2016-02-03 Photocure Asa Use
GB201522398D0 (en) 2015-12-18 2016-02-03 Photocure As Device for photodynamic therapy
CN106187793A (zh) * 2016-01-26 2016-12-07 赵鸣 5‑氨基酮戊酸及其衍生物的盐化合物和应用
RU2611441C2 (ru) * 2016-04-28 2017-02-22 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский радиологический центр" Министерства здравоохранения Российской Федерации (ФГБУ "НМИРЦ" Минздрава России) Способ получения гидрохлорида метилового эфира 5-аминолевулиновой кислоты
PT3576846T (pt) 2017-02-06 2021-03-09 3Skin As Composição de protector solar
CN108088838A (zh) * 2017-12-13 2018-05-29 西南大学 双[2,4,6-三氯苯基]草酸酯在测定链格孢霉毒素中的应用及方法
CN108440319B (zh) * 2018-04-26 2021-05-18 爱斯特（成都）生物制药股份有限公司 一种制备盐酸氨基乙酰丙酸的方法
EP3868372A1 (en) 2020-02-19 2021-08-25 JLP Health GmbH A pharmaceutical combination of an artemisinin compound and a heme synthesis modulator for treating cancer
CN116162038A (zh) * 2023-01-06 2023-05-26 河南省精细化工研究院有限公司 一种5-氨基乙酰丙酸盐酸盐的环保型生产工艺
WO2024184417A1 (en) 2023-03-07 2024-09-12 Photocure Asa Therapy for bladder cancer

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5079262A (en) 1989-07-28 1992-01-07 Queen's University At Kingston Method of detection and treatment of malignant and non-malignant lesions utilizing 5-aminolevulinic acid
JP2767318B2 (ja) 1990-04-11 1998-06-18 株式会社コスモ総合研究所 ５―アミノレブリン酸アルキルエステル又はその塩及びその製造方法並びにこれを有効成分とする除草剤
US5284973A (en) 1990-10-29 1994-02-08 Japan Tobacco Inc. Method of preparing an acid additional salt of delta-aminolevulinic acid
DE69109444T2 (de) * 1990-10-29 1995-09-28 Japan Tobacco Inc Ein Verfahren zur Herstellung von einem säureergänzenden Salz von delta-Aminolevulinsäure.
JP2613136B2 (ja) * 1991-05-14 1997-05-21 株式会社コスモ総合研究所 植物成長促進剤
JP2997979B2 (ja) * 1993-01-20 2000-01-11 株式会社コスモ総合研究所 ５−アミノレブリン酸の製造方法
JP2887554B2 (ja) * 1993-08-19 1999-04-26 株式会社コスモ総合研究所 植物の蓚酸含量低減剤
US5489572A (en) 1993-08-19 1996-02-06 Cosmo Research Institue Methods for reducing nitrate nitrogen and oxalic acids contents nin plants
GB9318841D0 (en) 1993-09-10 1993-10-27 Res Foundation Of The Norwegia Composition
JPH07238063A (ja) 1994-02-25 1995-09-12 Cosmo Sogo Kenkyusho:Kk ５−アミノレブリン酸の回収精製法
JP2896963B2 (ja) 1994-11-28 1999-05-31 株式会社コスモ総合研究所 植物の耐塩性向上剤
US6992107B1 (en) * 1995-03-10 2006-01-31 Photocure Asa Esters of 5-aminolevulinic acid and their use as photosensitizing compounds in photochemotherapy
EP0820432B1 (en) * 1995-03-10 2001-06-13 PhotoCure ASA Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy
JPH1112197A (ja) * 1997-06-18 1999-01-19 Cosmo Sogo Kenkyusho:Kk 悪性腫瘍診断剤及び治療剤
KR100580805B1 (ko) 1997-07-30 2006-05-17 와이어쓰 바소프레신 효능제 활성을 갖는 트리사이클릭 화합물, 이의 제조방법 및 이를 포함하는 약제학적 조성물
US5907058A (en) * 1998-07-29 1999-05-25 Midwest Research Institute Synthesis of an acid addition salt of delta-aminolevulinic acid from 5-bromo levulinic acid esters
GB0018528D0 (en) * 2000-07-27 2000-09-13 Photocure Asa Compounds
GB0018527D0 (en) 2000-07-27 2000-09-13 Photocure Asa Composition
GB0118251D0 (en) 2001-07-26 2001-09-19 Photocure Asa Method
CA2562170C (en) * 2004-03-30 2013-04-23 Cosmo Oil Co., Ltd. 5-aminolevulinic acid salt, process for producing the same and use thereof

Also Published As

Publication number Publication date
SI1727786T1 (sl) 2011-09-30
JP5164565B2 (ja) 2013-03-21
CA2561050A1 (en) 2005-10-06
RU2392266C2 (ru) 2010-06-20
ATE514672T1 (de) 2011-07-15
WO2005092838A1 (en) 2005-10-06
US20080064752A1 (en) 2008-03-13
CA2561050C (en) 2012-05-08
GB0406917D0 (en) 2004-04-28
US7888526B2 (en) 2011-02-15
AU2005225616B2 (en) 2011-08-18
JP2007530523A (ja) 2007-11-01
EP2308830B1 (en) 2017-06-14
AU2005225616A1 (en) 2005-10-06
RU2006135487A (ru) 2008-05-10
CN1938264A (zh) 2007-03-28
EP1727786A1 (en) 2006-12-06
PL1727786T3 (pl) 2011-11-30
DK1727786T3 (da) 2011-08-29
EP1727786B1 (en) 2011-06-29
ES2639021T3 (es) 2017-10-25
ES2367789T3 (es) 2011-11-08
US8692014B2 (en) 2014-04-08
CN1938264B (zh) 2012-05-23
EP2308830A1 (en) 2011-04-13
US20110125012A1 (en) 2011-05-26

Similar Documents

Publication Publication Date Title
PL1727786T3 (pl) Kwasowe addycyjne sole kwasu 5-aminolewulinowego lub jego pochodnych
PL1780197T3 (pl) 5-podstawione-2-fenyloaminobenzamidy jako inhibitory MEK
SI1814534T1 (sl) Derivati aminolevulinske kisline za zdravljenjeaken
TNSN07148A1 (en) (biphenyl) carboxylic acids and derivatives thereof
GB0018528D0 (en) Compounds
MXPA05008172A (es) Derivados de malonamida como inhibidores gamma-secretasa.
HK1104782A1 (en) Use of the salts, addition compounds and complex compounds of guanidinoacetic acid
WO2006122806A3 (en) 1,3-dihydro-imidazo [4,5-c] quinolin-2-ones as lipid kinase inhibitors
NL300176I1 (nl) Esters van 5-aminolevulinezuur als fotosensibiliserende middelen in de fotochemotherapie.
WO2007001940A3 (en) Imaging agents
RU2010136914A (ru) Средство и продукт питания для профилактики/уменьшения проявлений функционального расстройства пищеварения
MX2010008097A (es) Acido (-) 2-[1-(7-metil-2-(morfolin-4-il)-4-oxo-4h-pirido [1,2-a] pirimidin-9-il) etilamino]benzoico enantiomericamente puro, su uso en terapia medica, y una composicion farmaceutica que lo comprende - 026.
WO2003011274A3 (en) Use of a pde4 inhibitor in combination with an anticholinergic agent for the treatment of pulmonary disease such as asthma
IL169257A0 (en) Cycloalkene dicarboxylic acid compounds as anti-infammatory, immunomodulatory and anti-proliferatory agents
GEP20115269B (en) Substituted biphenyl carboxylic acids and derivatives thereof
WO2003006443A3 (de) 2-`4-(naphtalin-2yl)-thiazol-2-ylaminocarbonyl benzoesäure und 2-`4-(naphtalin-2yl)-pyrimidin-2-ylaminocarbonyl benzoesäure und andere verbindungen als telomerase-hemmer zur anwendung in der tumortherapie
WO2007119004A3 (fr) Methode de diagnostic in vitro ou ex vivo de desordres psychiatriques et/ou de dysbioses intestinales
UA94955C2 (en) Aqueous pharmaceutical formulation of 4-[((4-carboxybutyl)-{2-[(4-phenethyl-benzyl)oxy]-phenethyl}amino)methyl] benzoic acid
ATE479695T1 (de) Sulfopyranosylacylglycerol-derivate zur anwendung in kombination mit bestrahlung in einer tumor- radiotherapie
BR0316751A (pt) Análogos de gabapentina para fibromialgia e outros distúrbios relacionados
WO2006113462A3 (en) Formulations of quaternary ammonium neuromuscular blocking agents
EA200701797A1 (ru) Соли окаперидона и фармацевтические композиции, содержащие указанные соли
EA200401432A1 (ru) Сложноэфирные производные декагидроизохинолин-3-карбоновой кислоты в качестве анальгетиков
ATE360614T1 (de) Verbindung für die behandlung von atherosclerotischen und thrombotischen erkrankungen
WO2004032854A3 (en) Pharmaceutical compositions for treatment of parkinson's disease