EA200701797A1 - Соли окаперидона и фармацевтические композиции, содержащие указанные соли - Google Patents

Соли окаперидона и фармацевтические композиции, содержащие указанные соли

Info

Publication number
EA200701797A1
EA200701797A1 EA200701797A EA200701797A EA200701797A1 EA 200701797 A1 EA200701797 A1 EA 200701797A1 EA 200701797 A EA200701797 A EA 200701797A EA 200701797 A EA200701797 A EA 200701797A EA 200701797 A1 EA200701797 A1 EA 200701797A1
Authority
EA
Eurasian Patent Office
Prior art keywords
salts
pharmaceutical compositions
salt
ocaperidon
compositions containing
Prior art date
Application number
EA200701797A
Other languages
English (en)
Other versions
EA012039B1 (ru
Inventor
Стефано Бьонди
Арнольд Демайи
Цезарь Мондадори
Жан-Лоран Папарин
Original Assignee
Янссен Фармацевтика Н. В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Янссен Фармацевтика Н. В. filed Critical Янссен Фармацевтика Н. В.
Publication of EA200701797A1 publication Critical patent/EA200701797A1/ru
Publication of EA012039B1 publication Critical patent/EA012039B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Изобретение касается новых солей окаперидона и применения указанных солей, в частности, в фармацевтической промышленности. Изобретение раскрывает специфические соли окаперидона, обладающие повышенной водорастворимостью, а также терапевтические способы введения указанных солей, в частности, с целью лечения различных заболеваний центральной и периферической нервной системы, в особенности, центральной нервной системы. Изобретение также касается фармацевтических композиций, содержащих указанные соли, и способов получения указанных солей.
EA200701797A 2005-02-24 2006-02-24 Соли окаперидона и фармацевтические композиции, содержащие указанные соли EA012039B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05290428A EP1695973A1 (en) 2005-02-24 2005-02-24 Ocaperidone salt and pharmaceutical compositions containing the same
PCT/IB2006/000688 WO2006090285A1 (en) 2005-02-24 2006-02-24 Ocaperidone salts and pharmaceutical compositions containing the same

Publications (2)

Publication Number Publication Date
EA200701797A1 true EA200701797A1 (ru) 2008-02-28
EA012039B1 EA012039B1 (ru) 2009-06-30

Family

ID=35431923

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200701797A EA012039B1 (ru) 2005-02-24 2006-02-24 Соли окаперидона и фармацевтические композиции, содержащие указанные соли

Country Status (15)

Country Link
US (1) US20080200479A1 (ru)
EP (2) EP1695973A1 (ru)
JP (1) JP2008531544A (ru)
KR (1) KR20070105354A (ru)
CN (1) CN101142214B (ru)
AT (1) ATE414083T1 (ru)
AU (1) AU2006217540C1 (ru)
BR (1) BRPI0608560A2 (ru)
CA (1) CA2598327A1 (ru)
DE (1) DE602006003652D1 (ru)
EA (1) EA012039B1 (ru)
ES (1) ES2317507T3 (ru)
MX (1) MX2007010245A (ru)
NZ (1) NZ556748A (ru)
WO (1) WO2006090285A1 (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2184066B1 (en) * 2007-09-04 2013-11-06 Meiji Seika Pharma Co., Ltd. Injection, injection solution and injection kit preparation
KR101501253B1 (ko) * 2014-12-22 2015-03-12 제이투에이치바이오텍 (주) 결정성 페북소스타트 피돌레이트 염 및 이의 제조 방법
KR101829706B1 (ko) 2016-09-21 2018-02-19 씨제이헬스케어 주식회사 벤즈이미다졸 유도체의 산부가염

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU65921A1 (ru) * 1972-08-18 1974-02-21
US4575509A (en) * 1983-01-31 1986-03-11 Bristol-Myers Company Water-soluble formulations of m-AMSA with pyroglutamic acid
US5034397A (en) * 1985-12-12 1991-07-23 Bristol-Myers Squibb Co. Stable, water soluble salt compositions of M-AMSA in 1-methyl-2-pyrrolidinone
GB9008850D0 (en) * 1990-04-19 1990-06-13 Janssen Pharmaceutica Nv Novel 2,9-disubstituted-4h-pyridol(1,2-a)pyrimidin-4-ones
TW376319B (en) * 1993-04-28 1999-12-11 Janssen Pharmaceutica Nv Pharmaceutical composition containing risperidone pamoate and having a long acting activity for treating psychoses induced by the release of dopamine
US20030191141A1 (en) * 2002-03-28 2003-10-09 Inigo Pfeiffer Polymorphic form of 3-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4h-pyrido[1,2-alpha]pyrimidin-4-one and formulations thereof
KR100467669B1 (ko) * 2002-08-21 2005-01-24 씨제이 주식회사 암로디핀의 유기산염
AU2003293311A1 (en) * 2002-09-18 2004-04-23 Prosidion Ltd. Secondary binding site of dipeptidyl peptidase iv (dp iv)
US20040127733A1 (en) * 2002-10-31 2004-07-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg New beta-agonists, processes for preparing them and their use as pharmaceutical compositions
WO2004094415A1 (en) * 2003-04-22 2004-11-04 Synthon B.V. Risperidone monohydrochloride
US20040254173A1 (en) * 2003-06-13 2004-12-16 Leventer Steven M. Modulation of dopamine responses with substituted (S)-2,3-benzodiazepines
TW200524864A (en) * 2003-11-10 2005-08-01 Wyeth Corp Sulfonyltetrahydro-3H-benzo(E)indole-8-amine compounds as 5-hydroxytryptamine-6 ligands
DE602005002930T2 (de) * 2004-01-22 2008-07-24 Pfizer Inc. Sulfonamidderivate zur behandlung von krankheiten
US7649002B2 (en) * 2004-02-04 2010-01-19 Pfizer Inc (3,5-dimethylpiperidin-1yl)(4-phenylpyrrolidin-3-yl)methanone derivatives as MCR4 agonists
JP2007536270A (ja) * 2004-05-07 2007-12-13 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ イミダゾール誘導体のスケールアップ可能な合成
UY29016A1 (es) * 2004-07-20 2006-02-24 Boehringer Ingelheim Int Analogos de dipeptidos inhibidores de la hepatitis c
US7329763B1 (en) * 2006-09-11 2008-02-12 New Cell Formulations Ltd Creatine pyroglutamic acid salts and methods for their production and use in individuals

Also Published As

Publication number Publication date
US20080200479A1 (en) 2008-08-21
DE602006003652D1 (de) 2008-12-24
ES2317507T3 (es) 2009-04-16
EP1888577A1 (en) 2008-02-20
EP1888577B1 (en) 2008-11-12
AU2006217540C1 (en) 2011-11-03
ATE414083T1 (de) 2008-11-15
AU2006217540B2 (en) 2011-05-12
AU2006217540A1 (en) 2006-08-31
EA012039B1 (ru) 2009-06-30
KR20070105354A (ko) 2007-10-30
WO2006090285A1 (en) 2006-08-31
BRPI0608560A2 (pt) 2010-01-12
EP1695973A1 (en) 2006-08-30
NZ556748A (en) 2009-08-28
CN101142214B (zh) 2011-02-23
CN101142214A (zh) 2008-03-12
CA2598327A1 (en) 2006-08-31
MX2007010245A (es) 2007-09-07
JP2008531544A (ja) 2008-08-14

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU