PT1653930E - Métodos para a estabilização da atorvastatina - Google Patents

Métodos para a estabilização da atorvastatina Download PDF

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Publication number
PT1653930E
PT1653930E PT04738465T PT04738465T PT1653930E PT 1653930 E PT1653930 E PT 1653930E PT 04738465 T PT04738465 T PT 04738465T PT 04738465 T PT04738465 T PT 04738465T PT 1653930 E PT1653930 E PT 1653930E
Authority
PT
Portugal
Prior art keywords
kpa
stabilization
preferably less
partial pressure
gaseous mixture
Prior art date
Application number
PT04738465T
Other languages
English (en)
Inventor
Pavel Sebek
Alena Prokopova
Eduard Svoboda
Stanislav Radl
Jan Stach
Martin Svoboda
Andrej Kovacik
Adrian Danko
Roman Petro
Miroslav Strizinec
Original Assignee
Zentiva As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34117186&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1653930(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from CZ20032135A external-priority patent/CZ295027B6/cs
Priority claimed from CZ20040857A external-priority patent/CZ2004857A3/cs
Application filed by Zentiva As filed Critical Zentiva As
Publication of PT1653930E publication Critical patent/PT1653930E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
PT04738465T 2003-08-05 2004-08-05 Métodos para a estabilização da atorvastatina PT1653930E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CZ20032135A CZ295027B6 (cs) 2003-08-05 2003-08-05 Způsob stabilizace farmaceutické kompozice
CZ20040857A CZ2004857A3 (cs) 2004-08-03 2004-08-03 Zpusob stabilizace farmaceutické úcinné tuhé látky atorvastatinu

Publications (1)

Publication Number Publication Date
PT1653930E true PT1653930E (pt) 2008-03-12

Family

ID=34117186

Family Applications (1)

Application Number Title Priority Date Filing Date
PT04738465T PT1653930E (pt) 2003-08-05 2004-08-05 Métodos para a estabilização da atorvastatina

Country Status (13)

Country Link
US (1) US20080171784A1 (pt)
EP (1) EP1653930B1 (pt)
AT (1) ATE381322T1 (pt)
CA (1) CA2535225A1 (pt)
DE (1) DE602004010817T2 (pt)
EA (1) EA007345B1 (pt)
ES (1) ES2298763T3 (pt)
HR (1) HRP20060089B1 (pt)
PL (2) PL1653930T3 (pt)
PT (1) PT1653930E (pt)
RS (1) RS20060081A (pt)
SK (1) SK50462005A3 (pt)
WO (1) WO2005011638A2 (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI321132B (en) * 2004-09-28 2010-03-01 Teva Pharma Process for preparing forms of atorvastatin calcium substantially free of impurities
TWI318571B (en) * 2005-06-10 2009-12-21 Lilly Co Eli Formulation of a thienopyridine platelet aggregation inhibitor
EP1741427A1 (en) * 2005-07-06 2007-01-10 KRKA, D.D., Novo Mesto Pharmaceutical composition comprising simvastatin and ezetimibe
CA2547216A1 (en) * 2005-09-21 2007-03-21 Renuka D. Reddy Process for annealing amorphous atorvastatin
EP1810667A1 (en) 2006-01-20 2007-07-25 KRKA, tovarna zdravil, d.d., Novo mesto Pharmaceutical composition comprising amorphous atorvastatin
CZ300047B6 (cs) * 2007-03-02 2009-01-21 Zentiva, A. S. Farmaceutická kompozice s obsahem úcinné látky atorvastatinu
EP2127628A1 (en) 2008-05-27 2009-12-02 Ranbaxy Laboratories Limited Unit dose pack
TR200806300A2 (tr) * 2008-08-22 2010-03-22 B�Lg�� Mahmut Çözünürlük artırıcı farmasötlk formulasyon
US20120244220A1 (en) 2009-12-25 2012-09-27 Sawai Pharmaceutical Co., Ltd. Atrovastatin-containing coated preparation
US9717707B2 (en) 2011-12-08 2017-08-01 Hexal Ag Pharmaceutical statin composition
TWI636783B (zh) * 2012-04-18 2018-10-01 友霖生技醫藥股份有限公司 含匹伐他汀（ｐｉｔａｖａｓｔａｔｉｎ）穩定配方的醫藥組合物
CA2902346A1 (en) 2013-03-14 2014-09-18 Becton Dickinson France S.A.S. Packaging system for oxygen-sensitive drugs
EP2968132B1 (en) 2013-03-14 2017-09-13 Fresenius Kabi Deutschland GmbH Injectable morphine formulations
EP3184103A1 (en) 2015-12-21 2017-06-28 Hexal AG Pharmaceutical composition comprising atorvastatin or a salt thereof
EP3272336A1 (de) 2016-07-19 2018-01-24 Stada Arzneimittel Ag Atorvastatin-zusammensetzung

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5180589A (en) * 1988-03-31 1993-01-19 E. R. Squibb & Sons, Inc. Pravastatin pharmaceuatical compositions having good stability
EP0680320B1 (en) * 1993-01-19 1999-04-14 Warner-Lambert Company Stable oral ci-981 formulation and process of preparing same
CZ20024015A3 (cs) * 2000-06-09 2003-04-16 Lek Pharmaceutical D.D. Stabilní farmaceutický produkt a jeho formulace
EP1241110A1 (en) * 2001-03-16 2002-09-18 Pfizer Products Inc. Dispensing unit for oxygen-sensitive drugs
EP1243524A3 (en) * 2001-03-16 2004-04-07 Pfizer Products Inc. Pharmaceutical kit for oxygen-sensitive drugs
MXPA04007905A (es) * 2002-02-14 2004-11-26 Ranbaxy Lab Ltd Formulaciones de atorvastatin estabilizadas con adiciones de metal alcali.
SI21302A (sl) * 2002-10-11 2004-04-30 LEK farmacevtska dru�ba d.d. Stabiliziran farmacevtski izdelek z amorfno aktivno učinkovino

Also Published As

Publication number Publication date
ATE381322T1 (de) 2008-01-15
RS20060081A (en) 2008-06-05
US20080171784A1 (en) 2008-07-17
HRP20060089A2 (en) 2006-05-31
EP1653930B1 (en) 2007-12-19
DE602004010817T2 (de) 2008-12-11
EA200500819A1 (ru) 2006-02-24
PL379195A1 (pl) 2006-07-24
DE602004010817D1 (de) 2008-01-31
ES2298763T3 (es) 2008-05-16
HRP20060089B1 (en) 2008-05-31
EP1653930A2 (en) 2006-05-10
EA007345B1 (ru) 2006-08-25
WO2005011638A3 (en) 2005-10-20
SK50462005A3 (sk) 2005-09-08
PL1653930T3 (pl) 2008-06-30
WO2005011638A2 (en) 2005-02-10
CA2535225A1 (en) 2005-02-10

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