PT1539166E - Composições farmacêuticas compreendendo dextrometorfano e quinidina para o tratamento de distúrbios neurológicos - Google Patents

Composições farmacêuticas compreendendo dextrometorfano e quinidina para o tratamento de distúrbios neurológicos Download PDF

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Publication number
PT1539166E
PT1539166E PT03764769T PT03764769T PT1539166E PT 1539166 E PT1539166 E PT 1539166E PT 03764769 T PT03764769 T PT 03764769T PT 03764769 T PT03764769 T PT 03764769T PT 1539166 E PT1539166 E PT 1539166E
Authority
PT
Portugal
Prior art keywords
quinidine
pharmaceutical compositions
dextromethorphan
neurological disorders
treatment
Prior art date
Application number
PT03764769T
Other languages
English (en)
Portuguese (pt)
Inventor
Laura E Pope
Gerald Yakatan
James Berg
Richard A Smith
Original Assignee
Avanir Pharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=30116047&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1539166(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Avanir Pharmaceuticals filed Critical Avanir Pharmaceuticals
Publication of PT1539166E publication Critical patent/PT1539166E/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4748—Quinolines; Isoquinolines forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/49—Cinchonan derivatives, e.g. quinine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
PT03764769T 2002-07-17 2003-07-17 Composições farmacêuticas compreendendo dextrometorfano e quinidina para o tratamento de distúrbios neurológicos PT1539166E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US39666102P 2002-07-17 2002-07-17

Publications (1)

Publication Number Publication Date
PT1539166E true PT1539166E (pt) 2008-10-14

Family

ID=30116047

Family Applications (2)

Application Number Title Priority Date Filing Date
PT03764769T PT1539166E (pt) 2002-07-17 2003-07-17 Composições farmacêuticas compreendendo dextrometorfano e quinidina para o tratamento de distúrbios neurológicos
PT81544439T PT1980252E (pt) 2002-07-17 2003-07-17 Composições farmacêuticas incluindo dextrometorfano e quinidina para o tratamento de patologias neurológicas

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT81544439T PT1980252E (pt) 2002-07-17 2003-07-17 Composições farmacêuticas incluindo dextrometorfano e quinidina para o tratamento de patologias neurológicas

Country Status (23)

Country Link
US (12) US7659282B2 (cg-RX-API-DMAC7.html)
EP (6) EP1980252B1 (cg-RX-API-DMAC7.html)
JP (12) JP5082032B2 (cg-RX-API-DMAC7.html)
KR (7) KR20050043893A (cg-RX-API-DMAC7.html)
AT (1) ATE399553T1 (cg-RX-API-DMAC7.html)
AU (3) AU2003251971B9 (cg-RX-API-DMAC7.html)
BE (1) BE2013C064I2 (cg-RX-API-DMAC7.html)
CA (1) CA2492081C (cg-RX-API-DMAC7.html)
CY (2) CY1110405T1 (cg-RX-API-DMAC7.html)
DE (1) DE60321929D1 (cg-RX-API-DMAC7.html)
DK (2) DK1980252T3 (cg-RX-API-DMAC7.html)
ES (2) ES2309351T3 (cg-RX-API-DMAC7.html)
FR (1) FR13C0062I2 (cg-RX-API-DMAC7.html)
HU (2) HUE028100T2 (cg-RX-API-DMAC7.html)
IL (7) IL166166A0 (cg-RX-API-DMAC7.html)
LU (1) LU92323I2 (cg-RX-API-DMAC7.html)
NO (2) NO330626B1 (cg-RX-API-DMAC7.html)
PL (2) PL398445A1 (cg-RX-API-DMAC7.html)
PT (2) PT1539166E (cg-RX-API-DMAC7.html)
RU (1) RU2341265C2 (cg-RX-API-DMAC7.html)
SI (2) SI1980252T1 (cg-RX-API-DMAC7.html)
TW (1) TWI326214B (cg-RX-API-DMAC7.html)
WO (1) WO2004006930A1 (cg-RX-API-DMAC7.html)

Families Citing this family (144)

* Cited by examiner, † Cited by third party
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JP3405058B2 (ja) 1996-03-29 2003-05-12 スズキ株式会社 トランスファの潤滑構造
TWI326214B (en) * 2002-07-17 2010-06-21 Avanir Pharmaceuticals Inc Pharmaceutical compositions comprising dextromethorphan and quinidine for the treatment of neurological disorders
WO2004043365A2 (en) * 2002-11-06 2004-05-27 Azaya Therapeutics, Inc. Method for treatment of premature ejaculation in humans
WO2006038070A2 (en) * 2004-03-30 2006-04-13 Painceptor Pharma Corporation Compositions and methods for modulating gated ion channels
US20070191411A1 (en) * 2004-10-07 2007-08-16 Smith Richard A Enhancement of impaired motor and mental functions, using dextromethorphan and oxidase enzyme inhibitor
US20060205822A1 (en) * 2004-12-22 2006-09-14 Forest Laboratories, Inc. 1-Aminocyclohexane derivatives for the treatment of multiple sclerosis, emotional lability and pseudobulbar affect
WO2007092329A2 (en) * 2006-02-03 2007-08-16 Avanir Pharmaceuticals Pharmaceutical compositions for treating depression, anxiety and neurodegenerative disorders
US20160143901A1 (en) * 2006-02-03 2016-05-26 Avanir Pharmaceuticals, Inc. Pharmaceutical compositions comprising dextromethorphan and quinidine for the treatment of agitation in dementia
EP3632916B1 (en) 2007-05-01 2022-06-08 Concert Pharmaceuticals Inc. Morphinan compounds
MX370608B (es) * 2007-05-01 2019-12-18 Concert Pharmaceuticals Inc Compuestos de morfinano.
DK2792662T3 (da) 2007-05-01 2016-07-25 Concert Pharmaceuticals Inc Morphinanforbindelser
WO2009006194A1 (en) * 2007-06-28 2009-01-08 Avanir Pharmaceuticals Pharmaceutical compositions for the treatment of involuntary emotional expression disorder
JP5730769B2 (ja) 2008-09-19 2015-06-10 コンサート ファーマシューティカルズ インコーポレイテッド モルヒナン化合物
US20120122848A1 (en) * 2009-07-29 2012-05-17 Green Cross Corporation (+)-3-hydroxymorphinan derivatives as neuroprotectants
CA2712848A1 (en) * 2009-08-28 2011-02-28 Avanir Pharmaceuticals, Inc. A method of reducing cns and gastrointestinal side affects associated with long-term, dextromethorphan/low-dose quinidine combination therapy
BR112012028153A2 (pt) * 2010-05-03 2018-08-07 Tsh Biopharm Corporation Ltd composição farmacêutica e método para o tratamento de hipertensão
WO2012123449A1 (en) * 2011-03-14 2012-09-20 Boehringer Ingelheim International Gmbh N- cyclopropyl - n- piperidinylbenzamides as gpr119 modulators
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