PT1493441E - Agente terapêutico para a desordem de competência alimentar no estômago - Google Patents
Agente terapêutico para a desordem de competência alimentar no estômago Download PDFInfo
- Publication number
- PT1493441E PT1493441E PT03745958T PT03745958T PT1493441E PT 1493441 E PT1493441 E PT 1493441E PT 03745958 T PT03745958 T PT 03745958T PT 03745958 T PT03745958 T PT 03745958T PT 1493441 E PT1493441 E PT 1493441E
- Authority
- PT
- Portugal
- Prior art keywords
- group
- therapeutic agent
- competence
- stomach
- disorder
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 2
- 229940124597 therapeutic agent Drugs 0.000 title abstract 2
- 210000002784 stomach Anatomy 0.000 title 1
- 230000004308 accommodation Effects 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000001771 impaired effect Effects 0.000 abstract 1
- 125000002971 oxazolyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000000335 thiazolyl group Chemical group 0.000 abstract 1
- 125000001544 thienyl group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002104894 | 2002-04-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1493441E true PT1493441E (pt) | 2011-09-28 |
Family
ID=28786350
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT03745958T PT1493441E (pt) | 2002-04-08 | 2003-04-08 | Agente terapêutico para a desordem de competência alimentar no estômago |
Country Status (14)
| Country | Link |
|---|---|
| US (4) | US20050176788A1 (https=) |
| EP (2) | EP2301540A1 (https=) |
| JP (2) | JP5281226B2 (https=) |
| KR (4) | KR20110010837A (https=) |
| CN (2) | CN102125551B (https=) |
| AT (1) | ATE522214T1 (https=) |
| AU (1) | AU2003236326B2 (https=) |
| CA (1) | CA2481916C (https=) |
| CY (1) | CY1112057T1 (https=) |
| DK (1) | DK1493441T3 (https=) |
| ES (1) | ES2368732T3 (https=) |
| PT (1) | PT1493441E (https=) |
| SI (1) | SI1493441T1 (https=) |
| WO (1) | WO2003084537A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104447612A (zh) * | 2013-09-16 | 2015-03-25 | 天津市汉康医药生物技术有限公司 | 阿考替胺水合物晶型及其制备方法和用途 |
| CN103980226A (zh) * | 2014-05-10 | 2014-08-13 | 杭州新博思生物医药有限公司 | 盐酸阿考替胺水合物晶型及其制备方法 |
| CN105315225A (zh) * | 2014-07-07 | 2016-02-10 | 中美华世通生物医药科技（武汉）有限公司 | 阿考替胺的酸加成盐及其制备方法 |
| CN104045606B (zh) * | 2014-07-11 | 2015-09-30 | 杭州新博思生物医药有限公司 | 一锅法制备阿考替胺盐酸盐的方法 |
| CN109988121B (zh) * | 2019-04-28 | 2023-01-03 | 梯尔希（南京）药物研发有限公司 | 一种阿考替胺衍生物的制备方法 |
| KR20240083168A (ko) | 2021-07-14 | 2024-06-11 | 블루프린트 메디신즈 코포레이션 | Map4k1 저해제로서의 헤테로사이클 화합물 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU699008B2 (en) * | 1995-05-18 | 1998-11-19 | Zeria Pharmaceutical Co., Ltd. | Aminothiazole derivative, medicament containing the same, and intermediate for preperation of said compound |
| JPH10212271A (ja) * | 1997-01-31 | 1998-08-11 | Zeria Pharmaceut Co Ltd | Ｎ−置換ベンゾイルアミン誘導体、それを含有する医薬及び該化合物の製造中間体 |
| DE69814635T2 (de) * | 1997-06-24 | 2004-03-11 | Zeria Pharmaceutical Co., Ltd. | Verfahren zur herstellung von 2-hydroxybenzamidderivaten |
| US5981556A (en) * | 1997-07-22 | 1999-11-09 | G.D. Searle & Co. | 1,3-diazolino and 1,3-diazolidino heterocycles as useful nitric oxide synthase inhibitors |
| KR20010080025A (ko) * | 1998-11-23 | 2001-08-22 | 디르크 반테 | 소화불량 치료용 의약의 제조를 위한 프루칼로프라이드의용도 |
| EA004645B1 (ru) * | 1999-06-02 | 2004-06-24 | Янссен Фармацевтика Н.В. | Аминоалкилзамещенные производные бензопирана |
| DE60025261T2 (de) * | 1999-11-23 | 2006-08-24 | Janssen Pharmaceutica N.V. | Verwendung von 5ht3 antagonisten zur fundusentspannung |
| GB0002336D0 (en) * | 2000-02-01 | 2000-03-22 | Glaxo Group Ltd | Medicaments |
| WO2002020010A1 (en) * | 2000-09-08 | 2002-03-14 | Zeria Pharmaceutical Co., Ltd. | Pharmaceutical compositions containing aminothiazole derivatives for the treatment of colonic motor dysfunctions |
| US6986882B2 (en) * | 2002-01-17 | 2006-01-17 | Astrazeneca Ab | Therapy for functional dyspepsia |
-
2003
- 2003-04-08 KR KR1020117000220A patent/KR20110010837A/ko not_active Ceased
- 2003-04-08 CN CN201010611741.5A patent/CN102125551B/zh not_active Expired - Lifetime
- 2003-04-08 DK DK03745958.3T patent/DK1493441T3/da active
- 2003-04-08 EP EP10010621A patent/EP2301540A1/en not_active Withdrawn
- 2003-04-08 KR KR1020127005319A patent/KR20120037035A/ko not_active Ceased
- 2003-04-08 US US10/509,335 patent/US20050176788A1/en not_active Abandoned
- 2003-04-08 EP EP03745958A patent/EP1493441B1/en not_active Expired - Lifetime
- 2003-04-08 PT PT03745958T patent/PT1493441E/pt unknown
- 2003-04-08 AU AU2003236326A patent/AU2003236326B2/en not_active Expired
- 2003-04-08 KR KR10-2004-7015764A patent/KR20050002925A/ko not_active Ceased
- 2003-04-08 JP JP2003581777A patent/JP5281226B2/ja not_active Expired - Lifetime
- 2003-04-08 ES ES03745958T patent/ES2368732T3/es not_active Expired - Lifetime
- 2003-04-08 KR KR1020137022604A patent/KR101423284B1/ko not_active Expired - Lifetime
- 2003-04-08 CA CA2481916A patent/CA2481916C/en not_active Expired - Lifetime
- 2003-04-08 WO PCT/JP2003/004445 patent/WO2003084537A1/ja not_active Ceased
- 2003-04-08 AT AT03745958T patent/ATE522214T1/de active
- 2003-04-08 CN CNA038079755A patent/CN1646123A/zh active Pending
- 2003-04-08 SI SI200332073T patent/SI1493441T1/sl unknown
-
2009
- 2009-02-17 US US12/372,234 patent/US20090156652A1/en not_active Abandoned
-
2011
- 2011-01-05 JP JP2011000499A patent/JP5360075B2/ja not_active Expired - Lifetime
- 2011-11-16 CY CY20111101103T patent/CY1112057T1/el unknown
-
2014
- 2014-12-22 US US14/579,102 patent/US20150141475A1/en not_active Abandoned
-
2020
- 2020-08-20 US US16/998,637 patent/US20200375954A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2301540A1 (en) | 2011-03-30 |
| AU2003236326A1 (en) | 2003-10-20 |
| JP2011068692A (ja) | 2011-04-07 |
| KR20130101162A (ko) | 2013-09-12 |
| JP5281226B2 (ja) | 2013-09-04 |
| DK1493441T3 (da) | 2011-10-17 |
| US20090156652A1 (en) | 2009-06-18 |
| US20150141475A1 (en) | 2015-05-21 |
| SI1493441T1 (sl) | 2011-12-30 |
| EP1493441A1 (en) | 2005-01-05 |
| JP5360075B2 (ja) | 2013-12-04 |
| ATE522214T1 (de) | 2011-09-15 |
| CN102125551B (zh) | 2015-07-22 |
| US20050176788A1 (en) | 2005-08-11 |
| AU2003236326B2 (en) | 2008-02-28 |
| US20200375954A1 (en) | 2020-12-03 |
| KR101423284B1 (ko) | 2014-07-24 |
| WO2003084537A1 (en) | 2003-10-16 |
| ES2368732T3 (es) | 2011-11-21 |
| EP1493441A4 (en) | 2007-10-17 |
| CN102125551A (zh) | 2011-07-20 |
| CA2481916C (en) | 2013-02-26 |
| KR20120037035A (ko) | 2012-04-18 |
| JPWO2003084537A1 (ja) | 2005-08-11 |
| CA2481916A1 (en) | 2003-10-16 |
| KR20110010837A (ko) | 2011-02-07 |
| EP1493441B1 (en) | 2011-08-31 |
| CN1646123A (zh) | 2005-07-27 |
| KR20050002925A (ko) | 2005-01-10 |
| CY1112057T1 (el) | 2015-11-04 |
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