PT1454992E - Ensaio de quinase do linfoma anaplastico, reagentes e composicoes - Google Patents
Ensaio de quinase do linfoma anaplastico, reagentes e composicoesInfo
- Publication number
- PT1454992E PT1454992E PT03005186T PT03005186T PT1454992E PT 1454992 E PT1454992 E PT 1454992E PT 03005186 T PT03005186 T PT 03005186T PT 03005186 T PT03005186 T PT 03005186T PT 1454992 E PT1454992 E PT 1454992E
- Authority
- PT
- Portugal
- Prior art keywords
- reagents
- compositions
- kinase
- test
- anaplastic lymphoma
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines having two or more nitrogen atoms in the same ring, e.g. oxadiazines
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03005186A EP1454992B1 (en) | 2003-03-07 | 2003-03-07 | Anaplastic lymphoma kinase assay, reagents and compositions thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1454992E true PT1454992E (pt) | 2006-09-29 |
Family
ID=32798804
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT03005186T PT1454992E (pt) | 2003-03-07 | 2003-03-07 | Ensaio de quinase do linfoma anaplastico, reagentes e composicoes |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20070031907A1 (pt) |
| EP (1) | EP1454992B1 (pt) |
| JP (1) | JP2006519800A (pt) |
| CN (1) | CN100345978C (pt) |
| AT (1) | ATE328112T1 (pt) |
| CA (1) | CA2518094A1 (pt) |
| CY (1) | CY1106115T1 (pt) |
| DE (1) | DE60305634T2 (pt) |
| DK (1) | DK1454992T3 (pt) |
| ES (1) | ES2263862T3 (pt) |
| HK (1) | HK1068154A1 (pt) |
| IL (1) | IL170669A0 (pt) |
| PT (1) | PT1454992E (pt) |
| SI (1) | SI1454992T1 (pt) |
| WO (1) | WO2004079326A2 (pt) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8168383B2 (en) | 2006-04-14 | 2012-05-01 | Cell Signaling Technology, Inc. | Gene defects and mutant ALK kinase in human solid tumors |
| SI2450437T1 (sl) | 2006-04-14 | 2017-12-29 | Cell Signaling Technology Inc. | Okvarjenost genov in mutantna ALK kinaza v človeških solidnih tumorjih |
| EP2107054A1 (en) | 2008-04-01 | 2009-10-07 | Università Degli Studi Di Milano - Bicocca | Antiproliferative compounds and therapeutic uses thereof |
| US8871753B2 (en) | 2008-04-24 | 2014-10-28 | Incyte Corporation | Macrocyclic compounds and their use as kinase inhibitors |
| EP2161271A1 (en) | 2008-09-08 | 2010-03-10 | Università Degli Studi Di Milano - Bicocca | Alpha-carboline inhibitors of NMP-ALK, RET, and Bcr-Abl |
| US8765727B2 (en) | 2009-01-23 | 2014-07-01 | Incyte Corporation | Macrocyclic compounds and their use as kinase inhibitors |
| DK2975024T3 (en) * | 2009-06-10 | 2018-04-23 | Chugai Pharmaceutical Co Ltd | Tetracyclic compounds |
| CN101955995B (zh) * | 2010-06-17 | 2013-06-26 | 江苏迈迪基因生物科技有限公司 | 淋巴瘤相关的融合基因的诊断试剂盒 |
| WO2012019132A2 (en) | 2010-08-06 | 2012-02-09 | Cell Signaling Technology, Inc. | Anaplastic lymphoma kinase in kidney cancer |
| EP2606886B1 (en) | 2010-08-20 | 2020-01-08 | Chugai Seiyaku Kabushiki Kaisha | Composition comprising tetracyclic compound |
| JP6445426B2 (ja) | 2012-05-10 | 2018-12-26 | ザ ジェネラル ホスピタル コーポレイション | ヌクレオチド配列を決定する方法 |
| CN111388478A (zh) | 2012-09-25 | 2020-07-10 | 中外制药株式会社 | Ret抑制剂 |
| WO2014128235A1 (en) | 2013-02-22 | 2014-08-28 | F. Hoffmann-La Roche Ag | Methods of treating cancer and preventing drug resistance |
| JP7016215B2 (ja) | 2014-01-27 | 2022-02-04 | ザ ジェネラル ホスピタル コーポレイション | 配列決定のために核酸を調製する方法 |
| AR100187A1 (es) | 2014-04-25 | 2016-09-14 | Chugai Pharmaceutical Co Ltd | Composición farmacéutica que contiene un inhibidor de alk (quinasa de linfoma anaplásico) |
| US9714229B2 (en) | 2014-04-25 | 2017-07-25 | Chugai Seiyaku Kabushiki Kaisha | Crystal of tetracyclic compound |
| TWI765410B (zh) | 2014-08-08 | 2022-05-21 | 日商中外製藥股份有限公司 | ４環性化合物的非晶質體的用途 |
| WO2016114375A1 (ja) | 2015-01-16 | 2016-07-21 | 中外製薬株式会社 | 併用医薬 |
| EP4353830A2 (en) | 2016-09-15 | 2024-04-17 | ArcherDX, LLC | Methods of nucleic acid sample preparation for analysis of cell-free dna |
| EP3512947B1 (en) | 2016-09-15 | 2021-10-20 | ArcherDX, LLC | Methods of nucleic acid sample preparation |
| CN110191959B (zh) | 2016-11-02 | 2024-04-09 | 阿谢尔德克斯有限责任公司 | 用于免疫组库测序的核酸样品制备方法 |
| CN112585126B (zh) | 2018-09-04 | 2024-05-07 | 中外制药株式会社 | 四环化合物的制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05126833A (ja) * | 1991-10-31 | 1993-05-21 | Tosoh Corp | チロシンキナ−ゼ活性の免疫化学的測定法及びそのキツト |
| AU4281393A (en) * | 1992-04-10 | 1993-11-18 | Dana-Farber Cancer Institute, Inc. | Activation-state-specific phosphoprotein immunodetection |
| ES2136103T3 (es) * | 1992-06-22 | 1999-11-16 | Kyowa Hakko Kogyo Kk | Procedimiento para la preparacion de derivados de estaurosporina. |
| GB9314271D0 (en) * | 1993-07-09 | 1993-08-18 | Inst Of Cancer The Research | Cell growth factor receptors |
| DK0730740T3 (da) * | 1993-11-23 | 1998-09-28 | Genentech Inc | Kinasereceptoraktiveringsassay |
| US6001621A (en) * | 1993-11-23 | 1999-12-14 | Genetech, Inc. | Protein tyrosine kinases |
| US5529925A (en) * | 1993-12-03 | 1996-06-25 | St. Jude Children's Research Hospital | Nucleic acid sequences and fusion proteins present in human t(2;5) lymphoma |
| US5763198A (en) * | 1994-07-22 | 1998-06-09 | Sugen, Inc. | Screening assays for compounds |
| US5759787A (en) * | 1996-08-26 | 1998-06-02 | Tularik Inc. | Kinase assay |
| WO1998049317A2 (en) * | 1997-04-28 | 1998-11-05 | Sugen, Inc. | Diagnosis and treatment of phosphatase- 0r kinase-related disorders |
| WO2001004125A1 (fr) * | 1999-07-13 | 2001-01-18 | Kyowa Hakko Kogyo Co., Ltd. | Derives de staurosporine |
-
2003
- 2003-03-07 DE DE60305634T patent/DE60305634T2/de not_active Expired - Fee Related
- 2003-03-07 ES ES03005186T patent/ES2263862T3/es not_active Expired - Lifetime
- 2003-03-07 PT PT03005186T patent/PT1454992E/pt unknown
- 2003-03-07 AT AT03005186T patent/ATE328112T1/de not_active IP Right Cessation
- 2003-03-07 SI SI200330308T patent/SI1454992T1/sl unknown
- 2003-03-07 DK DK03005186T patent/DK1454992T3/da active
- 2003-03-07 EP EP03005186A patent/EP1454992B1/en not_active Expired - Lifetime
-
2004
- 2004-03-04 US US10/547,842 patent/US20070031907A1/en not_active Abandoned
- 2004-03-04 JP JP2006504533A patent/JP2006519800A/ja active Pending
- 2004-03-04 CA CA002518094A patent/CA2518094A1/en not_active Abandoned
- 2004-03-04 WO PCT/EP2004/002185 patent/WO2004079326A2/en active Application Filing
- 2004-03-04 CN CNB2004800060187A patent/CN100345978C/zh not_active Expired - Fee Related
-
2005
- 2005-02-17 HK HK05101314A patent/HK1068154A1/xx not_active IP Right Cessation
- 2005-09-05 IL IL170669A patent/IL170669A0/en unknown
-
2006
- 2006-07-04 CY CY20061100923T patent/CY1106115T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN100345978C (zh) | 2007-10-31 |
| CA2518094A1 (en) | 2004-09-16 |
| ATE328112T1 (de) | 2006-06-15 |
| DE60305634D1 (de) | 2006-07-06 |
| ES2263862T3 (es) | 2006-12-16 |
| HK1068154A1 (en) | 2005-04-22 |
| EP1454992A1 (en) | 2004-09-08 |
| CN1756850A (zh) | 2006-04-05 |
| JP2006519800A (ja) | 2006-08-31 |
| WO2004079326A2 (en) | 2004-09-16 |
| US20070031907A1 (en) | 2007-02-08 |
| EP1454992B1 (en) | 2006-05-31 |
| WO2004079326A3 (en) | 2004-12-09 |
| DK1454992T3 (da) | 2006-10-02 |
| IL170669A0 (en) | 2011-08-01 |
| CY1106115T1 (el) | 2011-06-08 |
| DE60305634T2 (de) | 2006-09-21 |
| SI1454992T1 (sl) | 2006-10-31 |
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