PT1392287E - Métodos para tratamento de doença de alzheimer e/ou regulação dos níveis de peptídeos β amilóide num sujeito - Google Patents

Métodos para tratamento de doença de alzheimer e/ou regulação dos níveis de peptídeos β amilóide num sujeito Download PDF

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Publication number
PT1392287E
PT1392287E PT02774113T PT02774113T PT1392287E PT 1392287 E PT1392287 E PT 1392287E PT 02774113 T PT02774113 T PT 02774113T PT 02774113 T PT02774113 T PT 02774113T PT 1392287 E PT1392287 E PT 1392287E
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PT
Portugal
Prior art keywords
alkyl
group
aryl
independently selected
substituted
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PT02774113T
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English (en)
Portuguese (pt)
Inventor
Margaret Van Heek
Harry R Davis
Eric Mcfee Parker
Gwendolyn Tse Wong
Laura B Merkel
Original Assignee
Schering Corp
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Publication of PT1392287E publication Critical patent/PT1392287E/pt

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT02774113T 2001-05-25 2002-05-22 Métodos para tratamento de doença de alzheimer e/ou regulação dos níveis de peptídeos β amilóide num sujeito PT1392287E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29365101P 2001-05-25 2001-05-25
US32391101P 2001-09-21 2001-09-21

Publications (1)

Publication Number Publication Date
PT1392287E true PT1392287E (pt) 2007-02-28

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Family Applications (1)

Application Number Title Priority Date Filing Date
PT02774113T PT1392287E (pt) 2001-05-25 2002-05-22 Métodos para tratamento de doença de alzheimer e/ou regulação dos níveis de peptídeos β amilóide num sujeito

Country Status (14)

Country Link
US (1) US20030013699A1 (cg-RX-API-DMAC7.html)
EP (1) EP1392287B8 (cg-RX-API-DMAC7.html)
JP (1) JP2004532868A (cg-RX-API-DMAC7.html)
AR (1) AR038956A1 (cg-RX-API-DMAC7.html)
AT (1) ATE345792T1 (cg-RX-API-DMAC7.html)
AU (1) AU2002308778A1 (cg-RX-API-DMAC7.html)
CA (1) CA2447884A1 (cg-RX-API-DMAC7.html)
CY (1) CY1105922T1 (cg-RX-API-DMAC7.html)
DE (1) DE60216275T2 (cg-RX-API-DMAC7.html)
DK (1) DK1392287T3 (cg-RX-API-DMAC7.html)
ES (1) ES2275007T3 (cg-RX-API-DMAC7.html)
MX (1) MXPA03010843A (cg-RX-API-DMAC7.html)
PT (1) PT1392287E (cg-RX-API-DMAC7.html)
WO (1) WO2002096415A2 (cg-RX-API-DMAC7.html)

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EP1562582A1 (en) 2002-11-06 2005-08-17 Schering Corporation Cholesterol absorption inhibitors for the treatment of demyelination
WO2004081002A1 (en) 2003-03-07 2004-09-23 Schering Corporation Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
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JP2006519869A (ja) 2003-03-07 2006-08-31 シェーリング コーポレイション 置換アゼチジノン化合物、置換アゼチジノン化合物を調製するためのプロセス、それらの処方物および使用
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JP4971794B2 (ja) * 2003-05-15 2012-07-11 ロスカンプ リサーチ エルエルシー アミロイド沈積、アミロイド神経毒性およびミクログリオーシスを低減する方法
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Also Published As

Publication number Publication date
EP1392287B8 (en) 2007-01-10
AR038956A1 (es) 2005-02-02
AU2002308778A1 (en) 2002-12-09
JP2004532868A (ja) 2004-10-28
WO2002096415A3 (en) 2003-01-16
US20030013699A1 (en) 2003-01-16
ATE345792T1 (de) 2006-12-15
DE60216275D1 (de) 2007-01-04
EP1392287B1 (en) 2006-11-22
EP1392287A2 (en) 2004-03-03
CA2447884A1 (en) 2002-12-05
DK1392287T3 (da) 2007-03-19
WO2002096415A2 (en) 2002-12-05
DE60216275T2 (de) 2007-06-21
CY1105922T1 (el) 2011-04-06
ES2275007T3 (es) 2007-06-01
MXPA03010843A (es) 2004-02-17

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