PT1356030E - Gene runx3 apresentando actividade antitumoral e sua utilização - Google Patents

Gene runx3 apresentando actividade antitumoral e sua utilização Download PDF

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Publication number
PT1356030E
PT1356030E PT01902862T PT01902862T PT1356030E PT 1356030 E PT1356030 E PT 1356030E PT 01902862 T PT01902862 T PT 01902862T PT 01902862 T PT01902862 T PT 01902862T PT 1356030 E PT1356030 E PT 1356030E
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PT
Portugal
Prior art keywords
runx3
development
cancer
present
runx3 gene
Prior art date
Application number
PT01902862T
Other languages
English (en)
Inventor
Suk-Chul Bae
Yoshiaki Ito
Original Assignee
Suk-Chul Bae
Yoshiaki Ito
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Suk-Chul Bae, Yoshiaki Ito filed Critical Suk-Chul Bae
Publication of PT1356030E publication Critical patent/PT1356030E/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747—Apoptosis related proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Pulmonology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
PT01902862T 2001-01-29 2001-01-30 Gene runx3 apresentando actividade antitumoral e sua utilização PT1356030E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR10-2001-0004018A KR100475649B1 (ko) 2001-01-29 2001-01-29 항암활성을 나타내는 ｒｕｎｘ３ 유전자 및 그의 용도

Publications (1)

Publication Number Publication Date
PT1356030E true PT1356030E (pt) 2008-10-30

Family

ID=19705043

Family Applications (1)

Application Number Title Priority Date Filing Date
PT01902862T PT1356030E (pt) 2001-01-29 2001-01-30 Gene runx3 apresentando actividade antitumoral e sua utilização

Country Status (10)

Country Link
US (2) US7368255B2 (pt)
EP (1) EP1356030B1 (pt)
JP (1) JP4018542B2 (pt)
KR (1) KR100475649B1 (pt)
AT (1) ATE402256T1 (pt)
DE (1) DE60135022D1 (pt)
DK (1) DK1356030T3 (pt)
ES (1) ES2310545T3 (pt)
PT (1) PT1356030E (pt)
WO (1) WO2002061069A1 (pt)

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GB0307428D0 (en) 2003-03-31 2003-05-07 Medical Res Council Compartmentalised combinatorial chemistry
WO2005040814A1 (en) * 2003-10-14 2005-05-06 Cancer Research Technology Limited Methods and means of cancer detection by histone modification
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WO2006057623A1 (en) * 2004-11-29 2006-06-01 National University Of Singapore Runx3 antibodies and method of obtaining the antibodies
KR100748185B1 (ko) * 2005-01-31 2007-08-10 한국생명공학연구원 Ｌｒｒｃ3ｂ 유전자를 포함하는 항암용 조성물 및 상기유전자를 이용한 진단방법
US8268572B2 (en) * 2005-03-04 2012-09-18 Dana-Farber Cancer Institute, Inc. Methods to identify inhibitors of Runx1-mediated expression of nociceptive receptors and ion channels
US7611847B2 (en) 2005-06-01 2009-11-03 Agency For Science, Technology And Research Method for identifying an intestinal phenotype
WO2006132248A1 (ja) * 2005-06-07 2006-12-14 Daiichi Pharmaceutical Co., Ltd. Ｒｕｎｘのユビキチン化方法
EP1984738A2 (en) 2006-01-11 2008-10-29 Raindance Technologies, Inc. Microfluidic devices and methods of use in the formation and control of nanoreactors
JP2009531065A (ja) * 2006-03-29 2009-09-03 ジョン ウェイン キャンサー インスティチュート エストロゲン受容体アルファのメチル化、およびその使用
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US8592221B2 (en) 2007-04-19 2013-11-26 Brandeis University Manipulation of fluids, fluid components and reactions in microfluidic systems
EP2198042B1 (en) 2007-09-17 2016-11-02 MDxHealth SA Novel markers for bladder cancer detection
US20110021442A1 (en) * 2007-11-06 2011-01-27 Daewoong Jo Cell preamble runx3 recombinant proteins, polynucleotides encoding the same, and anticancer compositions including the same
EP2315629B1 (en) 2008-07-18 2021-12-15 Bio-Rad Laboratories, Inc. Droplet libraries
EP2320917A4 (en) * 2008-07-29 2011-11-09 Agency Science Tech & Res METHODS FOR PREVENTING, STOPPING OR INVERTING TUMORIGENESIS AND IDENTIFYING COMPOUNDS CAPABLE THEREFROM
KR102264822B1 (ko) 2008-11-10 2021-06-14 알닐람 파마슈티칼스 인코포레이티드 치료제 운반용 신규 지질 및 조성물
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US10520500B2 (en) 2009-10-09 2019-12-31 Abdeslam El Harrak Labelled silica-based nanomaterial with enhanced properties and uses thereof
WO2011079176A2 (en) 2009-12-23 2011-06-30 Raindance Technologies, Inc. Microfluidic systems and methods for reducing the exchange of molecules between droplets
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KR101878451B1 (ko) * 2011-09-06 2018-07-16 벤텍스 주식회사 약물전달기능을 갖는 언더웨어
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CN106011263B (zh) * 2016-06-28 2020-01-07 宁波大学 用于检测与胃癌相关的ndrg4基因甲基化程度的试剂盒及其应用
CN109789158B (zh) 2016-07-29 2022-06-03 国立大学法人京都大学 Runx抑制剂
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KR101994957B1 (ko) 2017-11-30 2019-07-01 고려대학교 산학협력단 Runx3 단백질 또는 이를 코딩하는 runx3 유전자를 포함하는 trail의 항암 효과 증진용 약학 조성물
WO2019210863A1 (zh) * 2018-05-03 2019-11-07 科济生物医药（上海）有限公司 免疫效应细胞及其应用
JP7144037B2 (ja) * 2018-07-25 2022-09-29 国立大学法人山口大学 がんの診断用バイオマーカー
KR20200086609A (ko) * 2019-01-08 2020-07-17 주식회사바이오러넥스 Runx3 유전자 또는 단백질을 유효성분으로 함유하는 K-Ras 돌연변이 폐암의 예방 또는 치료용 약학 조성물
CN112662764A (zh) * 2020-03-17 2021-04-16 博尔诚（北京）科技有限公司 一种检测11种癌症的探针组合物
KR20210131855A (ko) * 2020-04-23 2021-11-03 런엑스 주식회사 R-point 조절 단백질 복합체를 유효성분으로 포함하는 폐암 치료용 약학적 조성물, 상기 복합체의 형성 여부를 이용한 폐암 치료제 스크리닝 방법 및 폐암 진단 방법

Also Published As

Publication number Publication date
US20080261883A1 (en) 2008-10-23
US20040146986A1 (en) 2004-07-29
EP1356030B1 (en) 2008-07-23
DK1356030T3 (da) 2008-11-03
JP2004529619A (ja) 2004-09-30
US7368255B2 (en) 2008-05-06
ES2310545T3 (es) 2009-01-16
WO2002061069A1 (en) 2002-08-08
KR100475649B1 (ko) 2005-03-10
DE60135022D1 (de) 2008-09-04
EP1356030A4 (en) 2005-02-02
EP1356030A1 (en) 2003-10-29
KR20020063387A (ko) 2002-08-03
ATE402256T1 (de) 2008-08-15
JP4018542B2 (ja) 2007-12-05

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