DE69535107D1 - Detektion von änderungen von tumor-suppressor genen zur diagnose von krebs - Google Patents

Detektion von änderungen von tumor-suppressor genen zur diagnose von krebs

Info

Publication number
DE69535107D1
DE69535107D1 DE69535107T DE69535107T DE69535107D1 DE 69535107 D1 DE69535107 D1 DE 69535107D1 DE 69535107 T DE69535107 T DE 69535107T DE 69535107 T DE69535107 T DE 69535107T DE 69535107 D1 DE69535107 D1 DE 69535107D1
Authority
DE
Germany
Prior art keywords
diagnosis
cancer
cdk4i
detection
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69535107T
Other languages
English (en)
Inventor
Dennis A Carson
Tsutomu Nobori
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California
Original Assignee
University of California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22854518&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69535107(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by University of California filed Critical University of California
Application granted granted Critical
Publication of DE69535107D1 publication Critical patent/DE69535107D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DE69535107T 1994-04-14 1995-04-12 Detektion von änderungen von tumor-suppressor genen zur diagnose von krebs Expired - Lifetime DE69535107D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/227,800 US6689561B1 (en) 1994-04-14 1994-04-14 Tumor suppressor gene and methods for detection of cancer, monitoring of tumor progression and cancer treatment
PCT/US1995/004655 WO1995028169A1 (en) 1994-04-14 1995-04-12 Tumor suppressor gene and methods for detection of cancer, monitoring of tumor progression and cancer treatment

Publications (1)

Publication Number Publication Date
DE69535107D1 true DE69535107D1 (de) 2006-08-24

Family

ID=22854518

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69535107T Expired - Lifetime DE69535107D1 (de) 1994-04-14 1995-04-12 Detektion von änderungen von tumor-suppressor genen zur diagnose von krebs

Country Status (7)

Country Link
US (1) US6689561B1 (de)
EP (1) EP0756488B1 (de)
JP (2) JPH09511910A (de)
AT (1) ATE332979T1 (de)
AU (1) AU2385095A (de)
DE (1) DE69535107D1 (de)
WO (1) WO1995028169A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08510651A (ja) * 1994-03-18 1996-11-12 ミリアド・ジェネティックス・インコーポレイテッド Ｍｔｓ遺伝子、それにおける変異、およびｍｔｓ遺伝子配列を用いる癌の診断方法
CN1128049A (zh) * 1994-03-18 1996-07-31 犹他大学研究基金会 多肿瘤抑制因子基因种系突变及检测该基因癌肿倾向性的方法
US6060301A (en) * 1994-03-18 2000-05-09 Myriad Genetics, Inc. Vector containing MTS1E1β gene
DE19539130C2 (de) * 1995-02-28 1999-05-12 Max Planck Gesellschaft Mittel zur Therapie von Tumoren und anderen Hyperplasien
US7163925B1 (en) 1995-07-17 2007-01-16 Board Of Regents, The University Of Texas System p16 expression constructs and their application in cancer therapy
CA2227193A1 (en) * 1995-07-17 1997-02-06 Xiaomei Jin P16 expression constructs and their application in cancer therapy
JP2002503954A (ja) * 1997-04-01 2002-02-05 グラクソ、グループ、リミテッド 核酸増幅法
US6573044B1 (en) 1997-08-07 2003-06-03 The Regents Of The University Of California Methods of using chemical libraries to search for new kinase inhibitors
WO1999029851A1 (en) * 1997-12-05 1999-06-17 Chiron Corporation Human 'kismet' protein hkis acts as a tumor suppressor
WO1999034018A1 (en) * 1997-12-24 1999-07-08 The Regents Of The University Of California Methods of using chemical libraries to search for new kinase inhibitors
US6289229B1 (en) 1998-01-20 2001-09-11 Scimed Life Systems, Inc. Readable probe array for in vivo use
US6797471B2 (en) * 2000-08-04 2004-09-28 Board Of Regents, The University Of Texas System Detection and diagnosis of smoking related cancers
GB0413346D0 (en) * 2004-06-15 2004-07-21 Theryte Ltd Treating cancer
US20060188507A1 (en) * 2005-02-11 2006-08-24 Elias Georges Methods for identifying chemotherapeutic resistance in non-hematopoietic tumors
US20070218480A1 (en) * 2006-01-25 2007-09-20 The Board Of Regents Of The University Of Texas System Detection and diagnosis of smoking related cancers
US20100086918A1 (en) * 2006-07-31 2010-04-08 The Regents Of The University Of California Methods for High Sensitivity Detection of Genetic Polymorphisms
WO2009077642A1 (en) * 2007-12-19 2009-06-25 University Of Helsinki Screening method
US8642007B2 (en) 2010-09-20 2014-02-04 Yanping Kong Method and compound for treatment of cancer using phosphorous-32 labeled DNA

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4681840A (en) * 1984-01-18 1987-07-21 The United States Of America As Represented By The Secretary Of Commerce Deoxyribonucleic acid molecules useful as probes for detecting oncogenes incorporated into chromosomal DNA
US6211334B1 (en) * 1992-10-16 2001-04-03 Cold Spring Harbor Cell-cycle regulatory proteins, and uses related thereto
DE69333043T2 (de) * 1992-10-16 2004-05-06 Cold Spring Harbor Laboratory Umlagerung des cyclin komlexes und seine darauf bezogenen anwendungen
JPH08510651A (ja) * 1994-03-18 1996-11-12 ミリアド・ジェネティックス・インコーポレイテッド Ｍｔｓ遺伝子、それにおける変異、およびｍｔｓ遺伝子配列を用いる癌の診断方法
US5691147A (en) * 1994-06-02 1997-11-25 Mitotix, Inc. CDK4 binding assay
CA2227193A1 (en) * 1995-07-17 1997-02-06 Xiaomei Jin P16 expression constructs and their application in cancer therapy

Also Published As

Publication number Publication date
JPH09511910A (ja) 1997-12-02
ATE332979T1 (de) 2006-08-15
US6689561B1 (en) 2004-02-10
EP0756488A4 (de) 1997-07-02
EP0756488B1 (de) 2006-07-12
EP0756488A1 (de) 1997-02-05
JP2005245469A (ja) 2005-09-15
AU2385095A (en) 1995-11-10
WO1995028169A1 (en) 1995-10-26

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