UA93344C2 - ПОЛИМОРФИЗМ ЧЕЛОВЕЧЕСКОГО ГЕНА NBS1 657del5, КОТОРЫЙ ИСПОЛЬЗУЕТСЯ ДЛЯ ДИАГНОСТИКИ УНАСЛЕДОВАННОЙ СКЛОННОСТИ K РАКУ ПРОСТАТЫ ИЛИ ИНВАЗИВНОГО РАКУ МОЛОЧНОЙ ЖЕЛЕЗЫ ДОЛЬКОВОГО ПОДТИПА - Google Patents

ПОЛИМОРФИЗМ ЧЕЛОВЕЧЕСКОГО ГЕНА NBS1 657del5, КОТОРЫЙ ИСПОЛЬЗУЕТСЯ ДЛЯ ДИАГНОСТИКИ УНАСЛЕДОВАННОЙ СКЛОННОСТИ K РАКУ ПРОСТАТЫ ИЛИ ИНВАЗИВНОГО РАКУ МОЛОЧНОЙ ЖЕЛЕЗЫ ДОЛЬКОВОГО ПОДТИПА

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Publication number
UA93344C2
UA93344C2 UAA200600302A UAA200600302A UA93344C2 UA 93344 C2 UA93344 C2 UA 93344C2 UA A200600302 A UAA200600302 A UA A200600302A UA A200600302 A UAA200600302 A UA A200600302A UA 93344 C2 UA93344 C2 UA 93344C2
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UA
Ukraine
Prior art keywords
nbs1
lobular
subtype
prostate gland
657del5
Prior art date
Application number
UAA200600302A
Other languages
English (en)
Ukrainian (uk)
Inventor
Цезар Цибулски
Ян Лубински
Богдан Горски
Бартломей Глиневич
Анджей Сикорски
Original Assignee
Поморска Академия Медична
Цезар Цибулски
Ян Лубински
Богдан Горски
Бартломей Глиневич
Анджей Сикорски
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Поморска Академия Медична, Цезар Цибулски, Ян Лубински, Богдан Горски, Бартломей Глиневич, Анджей Сикорски filed Critical Поморска Академия Медична
Publication of UA93344C2 publication Critical patent/UA93344C2/ru

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Изобретение относится к полинуклеотиду, который связан с повышенной наследственной склонностью к раку простаты или инвазивному раку молочной железы долькового подтипа, который кодирует молекулярный вариант полипептида NBS1, где указанный полинуклеотид содержит делецию пяти нуклеотидов, что соответствует позиции 18155, 18156, 18157, 18158 или гена NBS1 (657del5) и к диагностическому набору для идентификации склонности к инвазивному раку молочной железы долькового подтипа или к раку простаты.
UAA200600302A 2003-06-13 2004-06-14 ПОЛИМОРФИЗМ ЧЕЛОВЕЧЕСКОГО ГЕНА NBS1 657del5, КОТОРЫЙ ИСПОЛЬЗУЕТСЯ ДЛЯ ДИАГНОСТИКИ УНАСЛЕДОВАННОЙ СКЛОННОСТИ K РАКУ ПРОСТАТЫ ИЛИ ИНВАЗИВНОГО РАКУ МОЛОЧНОЙ ЖЕЛЕЗЫ ДОЛЬКОВОГО ПОДТИПА UA93344C2 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL360642A PL201608B1 (pl) 2003-06-13 2003-06-13 Sposób i zestaw do wykrywania wysokiej genetycznie uwarunkowanej predyspozycji do raka prostaty oraz zastosowanie zmiany germinalnej w obrębie genu NBS1

Publications (1)

Publication Number Publication Date
UA93344C2 true UA93344C2 (ru) 2011-02-10

Family

ID=33550530

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200600302A UA93344C2 (ru) 2003-06-13 2004-06-14 ПОЛИМОРФИЗМ ЧЕЛОВЕЧЕСКОГО ГЕНА NBS1 657del5, КОТОРЫЙ ИСПОЛЬЗУЕТСЯ ДЛЯ ДИАГНОСТИКИ УНАСЛЕДОВАННОЙ СКЛОННОСТИ K РАКУ ПРОСТАТЫ ИЛИ ИНВАЗИВНОГО РАКУ МОЛОЧНОЙ ЖЕЛЕЗЫ ДОЛЬКОВОГО ПОДТИПА

Country Status (4)

Country Link
EA (1) EA011608B1 (ru)
PL (1) PL201608B1 (ru)
UA (1) UA93344C2 (ru)
WO (1) WO2004111272A2 (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11261494B2 (en) 2012-06-21 2022-03-01 The Chinese University Of Hong Kong Method of measuring a fractional concentration of tumor DNA
KR20170125044A (ko) 2015-02-10 2017-11-13 더 차이니즈 유니버시티 오브 홍콩 암 스크리닝 및 태아 분석을 위한 돌연변이 검출법
DK3325664T3 (da) 2015-07-23 2022-03-07 Univ Hong Kong Chinese Analyse af fragmenteringsmønstre for cellefrit DNA
CA3051509A1 (en) 2017-01-25 2018-08-02 The Chinese University Of Hong Kong Diagnostic applications using nucleic acid fragments

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999055716A1 (en) * 1998-04-27 1999-11-04 Virginia Mason Research Center A gene associated with nijmegen breakage syndrome, its gene product and methods for their use

Also Published As

Publication number Publication date
WO2004111272A2 (en) 2004-12-23
WO2004111272A3 (en) 2005-06-09
PL201608B1 (pl) 2009-04-30
PL360642A1 (en) 2004-12-27
EA200600012A1 (ru) 2007-08-31
EA011608B1 (ru) 2009-04-28

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