UA93344C2 - POLYMORPHISM OF HUMAN GENE NBS1 657del5, USED FOR DIAGNOSTICS OF INHERITED DISPOSITION TO PROSTATE GLAND CANCER OR INVASIVE BREAST CANCER OF LOBULAR SUBTYPE - Google Patents

POLYMORPHISM OF HUMAN GENE NBS1 657del5, USED FOR DIAGNOSTICS OF INHERITED DISPOSITION TO PROSTATE GLAND CANCER OR INVASIVE BREAST CANCER OF LOBULAR SUBTYPE

Info

Publication number
UA93344C2
UA93344C2 UAA200600302A UAA200600302A UA93344C2 UA 93344 C2 UA93344 C2 UA 93344C2 UA A200600302 A UAA200600302 A UA A200600302A UA A200600302 A UAA200600302 A UA A200600302A UA 93344 C2 UA93344 C2 UA 93344C2
Authority
UA
Ukraine
Prior art keywords
nbs1
lobular
subtype
prostate gland
657del5
Prior art date
Application number
UAA200600302A
Other languages
Russian (ru)
Ukrainian (uk)
Inventor
Цезар Цибулски
Ян Лубински
Богдан Горски
Бартломей Глиневич
Анджей Сикорски
Original Assignee
Поморска Академия Медична
Цезар Цибулски
Ян Лубински
Богдан Горски
Бартломей Глиневич
Анджей Сикорски
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Поморска Академия Медична, Цезар Цибулски, Ян Лубински, Богдан Горски, Бартломей Глиневич, Анджей Сикорски filed Critical Поморска Академия Медична
Publication of UA93344C2 publication Critical patent/UA93344C2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Hospice & Palliative Care (AREA)
  • Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

An invention relates to polynucleotide, related with increased original disposition to prostate gland cancer or invasive breast cancer of lobular subtype, coding molecular variant of polypeptide NBS1, where the mentioned polynucleotide contains deletion of five nucleotides, which is equivalent of position 18155, 18156, 18157, 18158 or gene NBS1 (657del5) and to the diagnostic set for identification of disposition to invasive breast cancer of lobular subtype and prostate gland cancer.
UAA200600302A 2003-06-13 2004-06-14 POLYMORPHISM OF HUMAN GENE NBS1 657del5, USED FOR DIAGNOSTICS OF INHERITED DISPOSITION TO PROSTATE GLAND CANCER OR INVASIVE BREAST CANCER OF LOBULAR SUBTYPE UA93344C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PL360642A PL201608B1 (en) 2003-06-13 2003-06-13 Method and set designed for detection of high genetic predisposition for prostate gland cancer as well as use of germinal change within the NBS1 gene

Publications (1)

Publication Number Publication Date
UA93344C2 true UA93344C2 (en) 2011-02-10

Family

ID=33550530

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200600302A UA93344C2 (en) 2003-06-13 2004-06-14 POLYMORPHISM OF HUMAN GENE NBS1 657del5, USED FOR DIAGNOSTICS OF INHERITED DISPOSITION TO PROSTATE GLAND CANCER OR INVASIVE BREAST CANCER OF LOBULAR SUBTYPE

Country Status (4)

Country Link
EA (1) EA011608B1 (en)
PL (1) PL201608B1 (en)
UA (1) UA93344C2 (en)
WO (1) WO2004111272A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11261494B2 (en) 2012-06-21 2022-03-01 The Chinese University Of Hong Kong Method of measuring a fractional concentration of tumor DNA
CN107771221B (en) 2015-02-10 2021-11-02 香港中文大学 Mutation detection for cancer screening and fetal analysis
HUE057821T2 (en) 2015-07-23 2022-06-28 Univ Hong Kong Chinese Analysis of fragmentation patterns of cell-free dna
US10633713B2 (en) 2017-01-25 2020-04-28 The Chinese University Of Hong Kong Diagnostic applications using nucleic acid fragments

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999055716A1 (en) * 1998-04-27 1999-11-04 Virginia Mason Research Center A gene associated with nijmegen breakage syndrome, its gene product and methods for their use

Also Published As

Publication number Publication date
WO2004111272A2 (en) 2004-12-23
WO2004111272A3 (en) 2005-06-09
EA011608B1 (en) 2009-04-28
EA200600012A1 (en) 2007-08-31
PL360642A1 (en) 2004-12-27
PL201608B1 (en) 2009-04-30

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