ATE332979T1 - Detektion von änderungen von tumor-suppressor genen zur diagnose von krebs - Google Patents
Detektion von änderungen von tumor-suppressor genen zur diagnose von krebsInfo
- Publication number
- ATE332979T1 ATE332979T1 AT95916999T AT95916999T ATE332979T1 AT E332979 T1 ATE332979 T1 AT E332979T1 AT 95916999 T AT95916999 T AT 95916999T AT 95916999 T AT95916999 T AT 95916999T AT E332979 T1 ATE332979 T1 AT E332979T1
- Authority
- AT
- Austria
- Prior art keywords
- detection
- changes
- cdk4i
- gene
- tumor suppressor
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- 108700025716 Tumor Suppressor Genes Proteins 0.000 title 1
- 102000044209 Tumor Suppressor Genes Human genes 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
- 101710154003 Cyclin-dependent kinase inhibitor 2A Proteins 0.000 abstract 4
- 102100024458 Cyclin-dependent kinase inhibitor 2A Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000013701 Cyclin-Dependent Kinase 4 Human genes 0.000 abstract 1
- 108010025464 Cyclin-Dependent Kinase 4 Proteins 0.000 abstract 1
- 238000012217 deletion Methods 0.000 abstract 1
- 230000037430 deletion Effects 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 108091006086 inhibitor proteins Proteins 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 102000054765 polymorphisms of proteins Human genes 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/227,800 US6689561B1 (en) | 1994-04-14 | 1994-04-14 | Tumor suppressor gene and methods for detection of cancer, monitoring of tumor progression and cancer treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE332979T1 true ATE332979T1 (de) | 2006-08-15 |
Family
ID=22854518
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95916999T ATE332979T1 (de) | 1994-04-14 | 1995-04-12 | Detektion von änderungen von tumor-suppressor genen zur diagnose von krebs |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6689561B1 (de) |
| EP (1) | EP0756488B1 (de) |
| JP (2) | JPH09511910A (de) |
| AT (1) | ATE332979T1 (de) |
| AU (1) | AU2385095A (de) |
| DE (1) | DE69535107D1 (de) |
| WO (1) | WO1995028169A1 (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI955415A7 (fi) * | 1994-03-18 | 1996-01-09 | Myriad Genetics Inc | MTS-geeni, sen mutaatiot ja menetelmät syövän toteamiseksi MTS-geenise kvenssejä käyttäen |
| EP0702730A4 (de) * | 1994-03-18 | 1997-05-07 | Univ Utah Res Found | Kermbahnmütationen im mts-gen und methoden zur detektion einer veranlagung von krebs im mts-gen |
| US6060301A (en) * | 1994-03-18 | 2000-05-09 | Myriad Genetics, Inc. | Vector containing MTS1E1β gene |
| DE19539130C2 (de) * | 1995-02-28 | 1999-05-12 | Max Planck Gesellschaft | Mittel zur Therapie von Tumoren und anderen Hyperplasien |
| US7163925B1 (en) | 1995-07-17 | 2007-01-16 | Board Of Regents, The University Of Texas System | p16 expression constructs and their application in cancer therapy |
| HUP9901908A3 (en) | 1995-07-17 | 2000-02-28 | Univ Texas | P16 expression constructs and their application in cancer therapy |
| ATE364718T1 (de) * | 1997-04-01 | 2007-07-15 | Solexa Ltd | Verfahren zur vervielfältigung von nukleinsäure |
| US6573044B1 (en) | 1997-08-07 | 2003-06-03 | The Regents Of The University Of California | Methods of using chemical libraries to search for new kinase inhibitors |
| WO1999029851A1 (en) * | 1997-12-05 | 1999-06-17 | Chiron Corporation | Human 'kismet' protein hkis acts as a tumor suppressor |
| AU2010399A (en) * | 1997-12-24 | 1999-07-19 | Affymetrix, Inc. | Methods of using chemical libraries to search for new kinase inhibitors |
| US6289229B1 (en) | 1998-01-20 | 2001-09-11 | Scimed Life Systems, Inc. | Readable probe array for in vivo use |
| US6797471B2 (en) * | 2000-08-04 | 2004-09-28 | Board Of Regents, The University Of Texas System | Detection and diagnosis of smoking related cancers |
| GB0413346D0 (en) * | 2004-06-15 | 2004-07-21 | Theryte Ltd | Treating cancer |
| WO2006123246A2 (en) * | 2005-02-11 | 2006-11-23 | Aurelium Biopharma Inc. | Methods for identifying chemotherapeutic resistance in non-hematopoietic tumors |
| EP1989329A2 (de) * | 2006-01-25 | 2008-11-12 | Board of Regents, The University of Texas System | Erkennung und diagnose von durch rauchen bedingten krebserkrankungen |
| WO2008016615A2 (en) * | 2006-07-31 | 2008-02-07 | The Regents Of The University Of California | Methods for high sensitivity detection of genetic polymorphisms |
| WO2009077642A1 (en) * | 2007-12-19 | 2009-06-25 | University Of Helsinki | Screening method |
| US8642007B2 (en) | 2010-09-20 | 2014-02-04 | Yanping Kong | Method and compound for treatment of cancer using phosphorous-32 labeled DNA |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4681840A (en) * | 1984-01-18 | 1987-07-21 | The United States Of America As Represented By The Secretary Of Commerce | Deoxyribonucleic acid molecules useful as probes for detecting oncogenes incorporated into chromosomal DNA |
| US6211334B1 (en) * | 1992-10-16 | 2001-04-03 | Cold Spring Harbor | Cell-cycle regulatory proteins, and uses related thereto |
| KR100331363B1 (ko) * | 1992-10-16 | 2002-12-05 | 콜드 스프링 하버 래보레이토리 | 사이클린복합체재배열및그것과관련된용도 |
| FI955415A7 (fi) * | 1994-03-18 | 1996-01-09 | Myriad Genetics Inc | MTS-geeni, sen mutaatiot ja menetelmät syövän toteamiseksi MTS-geenise kvenssejä käyttäen |
| US5691147A (en) * | 1994-06-02 | 1997-11-25 | Mitotix, Inc. | CDK4 binding assay |
| HUP9901908A3 (en) * | 1995-07-17 | 2000-02-28 | Univ Texas | P16 expression constructs and their application in cancer therapy |
-
1994
- 1994-04-14 US US08/227,800 patent/US6689561B1/en not_active Expired - Lifetime
-
1995
- 1995-04-12 JP JP7527128A patent/JPH09511910A/ja active Pending
- 1995-04-12 WO PCT/US1995/004655 patent/WO1995028169A1/en not_active Ceased
- 1995-04-12 AT AT95916999T patent/ATE332979T1/de not_active IP Right Cessation
- 1995-04-12 EP EP95916999A patent/EP0756488B1/de not_active Expired - Lifetime
- 1995-04-12 AU AU23850/95A patent/AU2385095A/en not_active Abandoned
- 1995-04-12 DE DE69535107T patent/DE69535107D1/de not_active Expired - Lifetime
-
2005
- 2005-06-01 JP JP2005162026A patent/JP2005245469A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0756488A1 (de) | 1997-02-05 |
| AU2385095A (en) | 1995-11-10 |
| EP0756488B1 (de) | 2006-07-12 |
| US6689561B1 (en) | 2004-02-10 |
| EP0756488A4 (de) | 1997-07-02 |
| JP2005245469A (ja) | 2005-09-15 |
| DE69535107D1 (de) | 2006-08-24 |
| JPH09511910A (ja) | 1997-12-02 |
| WO1995028169A1 (en) | 1995-10-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |