PT1324691E - Sensor optico para medicao in situ de substancias analisaveis - Google Patents

Sensor optico para medicao in situ de substancias analisaveis

Info

Publication number
PT1324691E
PT1324691E PT01982427T PT01982427T PT1324691E PT 1324691 E PT1324691 E PT 1324691E PT 01982427 T PT01982427 T PT 01982427T PT 01982427 T PT01982427 T PT 01982427T PT 1324691 E PT1324691 E PT 1324691E
Authority
PT
Portugal
Prior art keywords
sensor
medication
situ
skin
optical sensor
Prior art date
Application number
PT01982427T
Other languages
English (en)
Inventor
Petersson Bo
Anders Weber
Original Assignee
Precisense As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Precisense As filed Critical Precisense As
Publication of PT1324691E publication Critical patent/PT1324691E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6846Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
    • A61B5/6847Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
    • A61B5/685Microneedles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Informatics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Optics & Photonics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Dermatology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Anesthesiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
PT01982427T 2000-10-13 2001-10-12 Sensor optico para medicao in situ de substancias analisaveis PT1324691E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0025147.0A GB0025147D0 (en) 2000-10-13 2000-10-13 Optical sensor for in situ measurement of analytes

Publications (1)

Publication Number Publication Date
PT1324691E true PT1324691E (pt) 2006-08-31

Family

ID=9901242

Family Applications (1)

Application Number Title Priority Date Filing Date
PT01982427T PT1324691E (pt) 2000-10-13 2001-10-12 Sensor optico para medicao in situ de substancias analisaveis

Country Status (15)

Country Link
US (1) US6671527B2 (pt)
EP (1) EP1324691B1 (pt)
JP (1) JP3873023B2 (pt)
AT (1) ATE325575T1 (pt)
AU (2) AU2002214016B2 (pt)
CA (1) CA2425337C (pt)
CY (1) CY1105129T1 (pt)
DE (1) DE60119556T2 (pt)
DK (1) DK1324691T3 (pt)
ES (1) ES2263671T3 (pt)
GB (1) GB0025147D0 (pt)
NO (1) NO334509B1 (pt)
NZ (1) NZ525567A (pt)
PT (1) PT1324691E (pt)
WO (1) WO2002030275A1 (pt)

Families Citing this family (137)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
AU770909B2 (en) 1998-08-26 2004-03-04 Sensors For Medicine And Science, Inc. Optical-based sensing devices
US7553280B2 (en) 2000-06-29 2009-06-30 Sensors For Medicine And Science, Inc. Implanted sensor processing system and method
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
CN100520372C (zh) * 2001-05-04 2009-07-29 医药及科学传感器公司 带有参考通道的电光传感器件
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7749174B2 (en) 2001-06-12 2010-07-06 Pelikan Technologies, Inc. Method and apparatus for lancet launching device intergrated onto a blood-sampling cartridge
US7699791B2 (en) 2001-06-12 2010-04-20 Pelikan Technologies, Inc. Method and apparatus for improving success rate of blood yield from a fingerstick
US7041068B2 (en) 2001-06-12 2006-05-09 Pelikan Technologies, Inc. Sampling module device and method
WO2002100252A2 (en) 2001-06-12 2002-12-19 Pelikan Technologies, Inc. Blood sampling apparatus and method
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
JP4209767B2 (ja) 2001-06-12 2009-01-14 ペリカン テクノロジーズ インコーポレイテッド 皮膚の性状の一時的変化に対する適応手段を備えた自動最適化形切開器具
WO2002100460A2 (en) 2001-06-12 2002-12-19 Pelikan Technologies, Inc. Electric lancet actuator
CA2500453A1 (en) * 2001-09-28 2003-04-03 Biovalve Technologies, Inc. Microneedle with membrane
GB0204640D0 (en) 2002-02-27 2002-04-10 Torsana Diabetes Diagnostics A Injection apparatus
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8360992B2 (en) 2002-04-19 2013-01-29 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US8372016B2 (en) 2002-04-19 2013-02-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling and analyte sensing
US7708701B2 (en) 2002-04-19 2010-05-04 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7648468B2 (en) 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US7175642B2 (en) 2002-04-19 2007-02-13 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
AU2003301064A1 (en) * 2002-12-17 2004-07-14 Massachusetts Institute Of Technology Stimuli-responsive systems for controlled drug delivery
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
BRPI0409435A (pt) * 2003-04-15 2006-04-18 Sensors For Med & Science Inc dispositivo de circuito impresso com antena integrada e sistema de processamento de sensor implantável com antena de placa de circuito impresso integrada
US7473548B2 (en) 2003-04-25 2009-01-06 Medtronic, Inc. Optical detector for enzyme activation
WO2004107975A2 (en) 2003-05-30 2004-12-16 Pelikan Technologies, Inc. Method and apparatus for fluid injection
WO2004107964A2 (en) 2003-06-06 2004-12-16 Pelikan Technologies, Inc. Blood harvesting device with electronic control
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
US7632234B2 (en) * 2003-08-29 2009-12-15 Medtronic, Inc. Implantable biosensor devices for monitoring cardiac marker molecules
US8282576B2 (en) 2003-09-29 2012-10-09 Sanofi-Aventis Deutschland Gmbh Method and apparatus for an improved sample capture device
US9351680B2 (en) 2003-10-14 2016-05-31 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a variable user interface
US7787923B2 (en) * 2003-11-26 2010-08-31 Becton, Dickinson And Company Fiber optic device for sensing analytes and method of making same
US7496392B2 (en) 2003-11-26 2009-02-24 Becton, Dickinson And Company Fiber optic device for sensing analytes
GB0329161D0 (en) 2003-12-16 2004-01-21 Precisense As Reagant for detecting an analyte
GB0329849D0 (en) 2003-12-23 2004-01-28 Precisense As Fluorometers
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
EP1706026B1 (en) 2003-12-31 2017-03-01 Sanofi-Aventis Deutschland GmbH Method and apparatus for improving fluidic flow and sample capture
GB0411162D0 (en) * 2004-05-19 2004-06-23 Precisense As Optical sensor for in vivo detection of analyte
US8828203B2 (en) 2004-05-20 2014-09-09 Sanofi-Aventis Deutschland Gmbh Printable hydrogels for biosensors
EP1765194A4 (en) 2004-06-03 2010-09-29 Pelikan Technologies Inc METHOD AND APPARATUS FOR MANUFACTURING A DEVICE FOR SAMPLING LIQUIDS
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
JP5502279B2 (ja) * 2004-10-28 2014-05-28 エコー セラピューティクス, インコーポレイテッド ヒドロゲルを使用した検体のサンプリングおよび分析のためのシステムおよび方法
GB0426823D0 (en) 2004-12-07 2005-01-12 Precisense As Sensor for detection of glucose
GB0426822D0 (en) * 2004-12-07 2005-01-12 Precisense As Sensor for detection of glucose
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
ES2313140T3 (es) * 2005-03-23 2009-03-01 F. Hoffmann-La Roche Ag Procedimiento para la determinacion de la concentracion de glucosa, mediante polarizacion de la fluorescencia.
US7308292B2 (en) 2005-04-15 2007-12-11 Sensors For Medicine And Science, Inc. Optical-based sensing devices
US7704704B2 (en) * 2005-09-28 2010-04-27 The Texas A&M University System Implantable system for glucose monitoring using fluorescence quenching
WO2007047922A2 (en) * 2005-10-19 2007-04-26 Smartcells, Inc. Polymer-drug conjugates
US20070173706A1 (en) * 2005-11-11 2007-07-26 Isense Corporation Method and apparatus for insertion of a sensor
US9615851B2 (en) 2005-11-11 2017-04-11 Waveform Technologies, Inc. Method and apparatus for insertion of a sensor
US9610459B2 (en) 2009-07-24 2017-04-04 Emkinetics, Inc. Cooling systems and methods for conductive coils
US9339641B2 (en) 2006-01-17 2016-05-17 Emkinetics, Inc. Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
EP2004241B1 (en) * 2006-03-28 2013-08-07 Glusense Ltd. Implantable sensor
US8126554B2 (en) 2006-05-17 2012-02-28 Cardiac Pacemakers, Inc. Implantable medical device with chemical sensor and related methods
CA2665134A1 (en) 2006-10-02 2008-04-10 Emkinetics, Inc. Method and apparatus for magnetic induction therapy
US9005102B2 (en) 2006-10-02 2015-04-14 Emkinetics, Inc. Method and apparatus for electrical stimulation therapy
US10786669B2 (en) 2006-10-02 2020-09-29 Emkinetics, Inc. Method and apparatus for transdermal stimulation over the palmar and plantar surfaces
US11224742B2 (en) 2006-10-02 2022-01-18 Emkinetics, Inc. Methods and devices for performing electrical stimulation to treat various conditions
US7713196B2 (en) 2007-03-09 2010-05-11 Nellcor Puritan Bennett Llc Method for evaluating skin hydration and fluid compartmentalization
US8560059B2 (en) * 2007-03-09 2013-10-15 Covidien Lp System and methods for optical sensing and drug delivery using microneedles
US20080275318A1 (en) * 2007-04-20 2008-11-06 Becton, Dickinson And Company Biosensors for measuring analytes in the interstitial fluid
GB0716159D0 (en) 2007-08-17 2007-09-26 Precisense As Injection apparatus
DK2200684T3 (en) 2007-08-17 2016-12-12 Medtronic Minimed Inc Injection device for making an injection in a pre-determined depth in the skin
CN100591388C (zh) * 2008-01-04 2010-02-24 南京大学 一种微针阵列注射器的制备方法
US9386944B2 (en) 2008-04-11 2016-07-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte detecting device
EP2174586B1 (de) * 2008-10-02 2014-12-10 EyeSense AG Implantierbares Sensorelement
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US9517023B2 (en) * 2009-06-01 2016-12-13 Profusa, Inc. Method and system for directing a localized biological response to an implant
JP2011001469A (ja) * 2009-06-18 2011-01-06 Terumo Corp 蛍光ハイドロゲルビーズの製造方法
JP5380174B2 (ja) * 2009-06-18 2014-01-08 テルモ株式会社 蛍光ハイドロゲルビーズおよびそれを用いた体内埋め込み用の糖類測定用センサー
JP2013508119A (ja) 2009-10-26 2013-03-07 エムキネティクス, インコーポレイテッド 神経、筋肉および身体組織の電磁刺激のための方法および装置
EP2537032A1 (en) * 2010-02-19 2012-12-26 Lightship Medical Limited Subcutaneous glucose sensor
US8795595B2 (en) 2010-04-07 2014-08-05 Medtronic Minimed, Inc. Sensor substrate systems and methods
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
JP5214036B2 (ja) 2010-04-20 2013-06-19 パナソニック株式会社 生体に含有される生体成分の濃度を測定する方法
US10010272B2 (en) 2010-05-27 2018-07-03 Profusa, Inc. Tissue-integrating electronic apparatus
US8588884B2 (en) 2010-05-28 2013-11-19 Emkinetics, Inc. Microneedle electrode
CN101905856B (zh) * 2010-06-11 2012-10-10 北京大学 一种用于透皮给药的平面空心微针的制备方法
CN103260501B (zh) 2010-10-06 2015-09-02 普罗弗萨股份有限公司 组织整合性传感器
WO2012046423A1 (ja) 2010-10-06 2012-04-12 パナソニック株式会社 生体に含有される生体成分の濃度を測定する方法
US8509868B2 (en) 2011-04-12 2013-08-13 Panasonic Corporation Method for measuring a concentration of a biogenic substance contained in a living body
US20130060106A1 (en) 2011-09-06 2013-03-07 Medtronic Minimed, Inc. Optical sensing systems and methods
US8999720B2 (en) 2011-11-17 2015-04-07 Medtronic Minimed, Inc. Aqueous radiation protecting formulations and methods for making and using them
JP5834192B2 (ja) 2013-01-25 2015-12-16 パナソニックIpマネジメント株式会社 生体内における被検物質の濃度を計測する計測方法、および、計測装置
WO2014160258A1 (en) 2013-03-14 2014-10-02 Profusa, Inc. Oxygen sensors
CA2904031A1 (en) 2013-03-14 2014-10-02 Profusa, Inc. Method and device for correcting optical signals
JP5896322B2 (ja) 2013-05-17 2016-03-30 パナソニックIpマネジメント株式会社 センサ埋込装置およびセンサ埋込システム
CN111544011B (zh) 2013-06-06 2023-06-06 普罗菲尤萨股份有限公司 用于探测来自植入传感器的光信号的设备和方法
US9504405B2 (en) 2013-10-23 2016-11-29 Verily Life Sciences Llc Spatial modulation of magnetic particles in vasculature by external magnetic field
US10542918B2 (en) 2013-10-23 2020-01-28 Verily Life Sciences Llc Modulation of a response signal to distinguish between analyte and background signals
US9936905B2 (en) 2013-10-25 2018-04-10 Medtronic Minimed, Inc. Sensor with optical interface
US20170055499A1 (en) * 2014-05-21 2017-03-02 Empire Technology Development Llc Tattoo and tattoo applicator for animal lifecycle monitoring
US9910035B1 (en) 2014-07-16 2018-03-06 Verily Life Sciences Llc Polyvalent functionalized nanoparticle-based in vivo diagnostic system
US9820690B1 (en) 2014-07-16 2017-11-21 Verily Life Sciences Llc Analyte detection system
US9874554B1 (en) 2014-07-16 2018-01-23 Verily Life Sciences Llc Aptamer-based in vivo diagnostic system
CN106999118B (zh) 2014-10-13 2020-07-17 葡萄糖传感器公司 分析物感测装置
US20160354500A1 (en) 2015-06-02 2016-12-08 Medtronic Minimed, Inc. Protective agents against e-beam irradiation for proteins in optical sensing chemistry
US10716500B2 (en) 2015-06-29 2020-07-21 Cardiac Pacemakers, Inc. Systems and methods for normalization of chemical sensor data based on fluid state changes
EP3445872A1 (en) 2016-04-20 2019-02-27 Glusense Ltd. Fret-based glucose-detection molecules
WO2018119204A1 (en) 2016-12-21 2018-06-28 Profusa, Inc. Polymerizable near-ir dyes
WO2018119400A1 (en) 2016-12-22 2018-06-28 Profusa, Inc. System and single-channel luminescent sensor for and method of determining analyte value
US10543288B2 (en) 2017-04-28 2020-01-28 Medtronic Minimed, Inc. Modified-dextrans for use in optical glucose assays
US10792378B2 (en) 2017-04-28 2020-10-06 Medtronics Minimed, Inc. Using a blue-shifted reference dye in an optical glucose assay
CN108968976B (zh) 2017-05-31 2022-09-13 心脏起搏器股份公司 具有化学传感器的植入式医疗设备
US12004853B2 (en) 2017-07-26 2024-06-11 Cardiac Pacemakers, Inc. Systems and methods for disambiguation of posture
CN109381195B (zh) 2017-08-10 2023-01-10 心脏起搏器股份公司 包括电解质传感器融合的系统和方法
CN109419515B (zh) 2017-08-23 2023-03-24 心脏起搏器股份公司 具有分级激活的可植入化学传感器
CN109864746B (zh) 2017-12-01 2023-09-29 心脏起搏器股份公司 用于医学装置的多模式分析物传感器
CN109864747B (zh) 2017-12-05 2023-08-25 心脏起搏器股份公司 多模式分析物传感器光电子接口
JPWO2019142913A1 (ja) * 2018-01-18 2021-03-04 国立大学法人 東京大学 3次元組織内のグルコース濃度マッピングのための蛍光マイクロ粒子
CN112294298A (zh) * 2019-08-02 2021-02-02 华广生技股份有限公司 生物传感器的植入装置及其植入方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
DE2655801C2 (de) * 1976-12-09 1986-06-26 Kernforschungsanlage Jülich GmbH, 5170 Jülich Injizierbare Suspension von Membranvesikeln aus Erythrozyten und Verfahren zur Herstellung der Suspension
US4344438A (en) 1978-08-02 1982-08-17 The United States Of America As Represented By The Department Of Health, Education And Welfare Optical sensor of plasma constituents
US4945050A (en) 1984-11-13 1990-07-31 Cornell Research Foundation, Inc. Method for transporting substances into living cells and tissues and apparatus therefor
US5101814A (en) * 1989-08-11 1992-04-07 Palti Yoram Prof System for monitoring and controlling blood glucose
US5342789A (en) 1989-12-14 1994-08-30 Sensor Technologies, Inc. Method and device for detecting and quantifying glucose in body fluids
US6040194A (en) * 1989-12-14 2000-03-21 Sensor Technologies, Inc. Methods and device for detecting and quantifying substances in body fluids
US5149655A (en) 1990-06-21 1992-09-22 Agracetus, Inc. Apparatus for genetic transformation
TW360548B (en) 1993-04-08 1999-06-11 Powderject Res Ltd Products for therapeutic use
US6011984A (en) 1995-11-22 2000-01-04 Minimed Inc. Detection of biological molecules using chemical amplification and optical sensors
GB9605690D0 (en) 1996-03-19 1996-05-22 Oxford Biosciences Ltd Particle delivery
ATE386934T1 (de) 1997-06-04 2008-03-15 Sensor Technologies Inc Methode und vorrichtung zum nachweis oder zur quantifizierung von kohlenhydrate enthaltenden verbindungen
JP2002517300A (ja) 1998-06-10 2002-06-18 ジョージア テック リサーチ コーポレイション 微小針デバイスおよび製造方法ならびにそれらの使用
GB9814506D0 (en) 1998-07-03 1998-09-02 Stanley Christopher J Optical sensor for insitu measurement of analytes
EP1140275A1 (en) 1998-12-18 2001-10-10 Minimed Inc. Insertion sets with micro-piercing members for use with medical devices and methods of using the same

Also Published As

Publication number Publication date
ATE325575T1 (de) 2006-06-15
JP3873023B2 (ja) 2007-01-24
US6671527B2 (en) 2003-12-30
NZ525567A (en) 2004-05-28
CA2425337C (en) 2012-01-10
AU1401602A (en) 2002-04-22
DK1324691T3 (da) 2006-09-11
NO20031685L (no) 2003-05-28
CA2425337A1 (en) 2002-04-18
AU2002214016B2 (en) 2005-06-16
JP2004510527A (ja) 2004-04-08
NO20031685D0 (no) 2003-04-11
GB0025147D0 (en) 2000-11-29
DE60119556T2 (de) 2007-01-25
EP1324691A1 (en) 2003-07-09
ES2263671T3 (es) 2006-12-16
CY1105129T1 (el) 2010-03-03
WO2002030275A1 (en) 2002-04-18
DE60119556D1 (de) 2006-06-14
EP1324691B1 (en) 2006-05-10
US20020058863A1 (en) 2002-05-16
NO334509B1 (no) 2014-03-24

Similar Documents

Publication Publication Date Title
PT1324691E (pt) Sensor optico para medicao in situ de substancias analisaveis
DE50013029D1 (de) Probenkammer zur Flüssigkeitsbehandlung biologischer Proben
BR9814386B1 (pt) aparelhos e métodos para determinar a concentração de um componente medicamente significante de um fluido biológico.
AR012351A1 (es) Un metodo y dispositivos para dividir muestras biologicas liquidas en microvolumenes
GB2365526B (en) Assay apparatus for measuring the amount of an analyte in a biological or environmental sample
NO20040098L (no) Optisk sensor inneholdende partikler for in situ maling av analytter
GB2350421B (en) Apparatus and method of testing a biological fluid
ATE520974T1 (de) Raman-spektralanalyse von unter der oberfläche liegenden geweben und flüssigkeiten
IL173339A0 (en) Biological fluid sampling and analyte measurement devices and methods
NO331202B1 (no) Optisk sensor for in-situ-maling av analytter
DE69934219D1 (de) Vorrichtung zur blutanalyse
AU8026100A (en) Device for and method of simultaneously measuring light scatter from multiple liquid samples
ITRM20030467A0 (it) Contenitore monouso per la centrifugazione ed il trattamento di un materiale biologico fluido.
AU2002312858A1 (en) Device and method for the optical measurement of chemical and/or biological samples
AR026485A1 (es) Disposicion detectora de muestras de un producto agricola y metodo de analizar muestras de un producto agricola usando dicha disposicion
DE60228196D1 (de) System und verfahren zur in-vitro-analyse von therapeutischen wirkstoffen
GB2332282B (en) Method and device for measuring the physical characteristics of a porous sample by displacing the fluids contained therein by centrifugation
DE50103797D1 (de) Vorrichtung und system zur abgabe bzw. aufnahme/abgabe von flüssigkeitsproben
TW200626897A (en) Biological test strip
EP1679541A4 (en) SAMPLE MONITORING METHOD AND MICROSCOPE AND CONFIGURATION LINE AND OPTICAL CONTACT LIQUID FOR USE THEREIN
ATA5052000A (de) Vorrichtung zur aeroben fermentation von biologischen substanzen
AU2001276346A1 (en) Refractometric method for carrying out long-term stable accurate measurement of the concentrations of dissolved substances and miniaturizable device for carrying out said method
EA200100544A1 (ru) Способ экспресс-диагностики физиологического состояния биологического объекта и устройство для его осуществления
FR2867969B1 (fr) Dispositif de soutien ou de maintien pour le corps humain ou animal et son procede d'application
FR2856792B1 (fr) Procede et dispositif de dosage d'un echantillon biologique ou chimique