PT1303475E - Processo para a preparacao de esteres do acido 6,8-di-hidroxioctanoico enantiomericamente puros por hidrogenacao catalitica assimetrica - Google Patents

Processo para a preparacao de esteres do acido 6,8-di-hidroxioctanoico enantiomericamente puros por hidrogenacao catalitica assimetrica

Info

Publication number
PT1303475E
PT1303475E PT01967196T PT01967196T PT1303475E PT 1303475 E PT1303475 E PT 1303475E PT 01967196 T PT01967196 T PT 01967196T PT 01967196 T PT01967196 T PT 01967196T PT 1303475 E PT1303475 E PT 1303475E
Authority
PT
Portugal
Prior art keywords
sub
preparation
asymmetric
hydrogenacao
acid esters
Prior art date
Application number
PT01967196T
Other languages
English (en)
Inventor
Rainer Gewald
Original Assignee
Viatris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viatris Gmbh filed Critical Viatris Gmbh
Publication of PT1303475E publication Critical patent/PT1303475E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D339/00Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/02Five-membered rings
    • C07D339/04Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/31Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/67Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of saturated acids
    • C07C69/716Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/32Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by aldehydo- or ketonic radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Epoxy Compounds (AREA)
PT01967196T 2000-07-27 2001-07-17 Processo para a preparacao de esteres do acido 6,8-di-hidroxioctanoico enantiomericamente puros por hidrogenacao catalitica assimetrica PT1303475E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10036516A DE10036516A1 (de) 2000-07-27 2000-07-27 Verfahren zur Herstellung von enantiomerenreinen 6,8-Dihydroxyoctansäureestern durch assymetrische katalytische Hydrierung

Publications (1)

Publication Number Publication Date
PT1303475E true PT1303475E (pt) 2005-09-30

Family

ID=7650351

Family Applications (1)

Application Number Title Priority Date Filing Date
PT01967196T PT1303475E (pt) 2000-07-27 2001-07-17 Processo para a preparacao de esteres do acido 6,8-di-hidroxioctanoico enantiomericamente puros por hidrogenacao catalitica assimetrica

Country Status (15)

Country Link
US (1) US6965029B2 (pt)
EP (1) EP1303475B1 (pt)
JP (1) JP2004505104A (pt)
AT (1) ATE297370T1 (pt)
AU (1) AU2001287635A1 (pt)
BR (1) BR0112773A (pt)
CA (1) CA2417269A1 (pt)
CZ (1) CZ2003191A3 (pt)
DE (2) DE10036516A1 (pt)
EE (1) EE200300038A (pt)
ES (1) ES2241866T3 (pt)
HU (1) HUP0301503A2 (pt)
PL (1) PL358717A1 (pt)
PT (1) PT1303475E (pt)
WO (1) WO2002010113A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1510517A1 (en) * 2003-09-01 2005-03-02 Lonza AG Process for the asymmetric hydrogenation of beta-amino ketones

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6163690A (ja) 1984-09-04 1986-04-01 Takasago Corp ルテニウム−ホスフイン錯体
JPS62265293A (ja) 1986-05-13 1987-11-18 Takasago Corp ルテニウム−ホスフイン錯体
JPS6341487A (ja) 1986-08-06 1988-02-22 Takasago Corp ルテニウム−ホスフイン錯体
DE3629116A1 (de) * 1986-08-27 1988-03-10 Asta Pharma Ag Verfahren zur herstellung enantiomerenreiner r-(+)-(alpha)-liponsaeure und s-(-)-(alpha)-liponsaeure (thioctsaeure) sowie nonen- beziehungsweise mesylderivate als zwischenprodukte hierfuer
DE3778857D1 (de) 1986-11-14 1992-06-11 Takasago Perfumery Co Ltd Katalytische produktion von optisch aktiven carbonsaeuren.
JPH0757758B2 (ja) 1988-10-24 1995-06-21 高砂香料工業株式会社 ルテニウム―ホスフィン錯体
DE59010810D1 (de) 1989-11-09 1998-04-16 Asta Medica Ag Arzneimittel enthaltend als Wirkstoff R-alpha-Liponsäure oder S-alpha-Liponsäure
JP2775335B2 (ja) * 1990-08-01 1998-07-16 高砂香料工業株式会社 ルテニウム―ホスフィン錯体及びその製造中間体
DE4037440A1 (de) 1990-11-24 1992-05-27 Basf Ag Verfahren zur herstellung von (6s)-6,8-dihydroxyoctansaeureestern
DE4330730A1 (de) 1993-09-10 1995-03-16 Bayer Ag Neue Bisphosphine für asymmetrische Hydrierkatalysatoren
IT1270082B (it) 1994-07-12 1997-04-28 Univ Degli Studi Milano Difosfine eteroaromatiche come leganti chirali, complessi tra dette difosfine e metalli di transizione ed impiego di detti complessi come catalizzatori chirali
DE19709069C2 (de) 1997-03-06 2000-04-06 Asta Medica Ag Enantiomerenreine 3-Hydroxyoctandisäurediester, Verfahren zur Herstellung derselben durch asymmetrische katalytische Hydrierung sowie Verfahren zur Herstellung von R-(+)- und S-(-)-alpha-Liponsäure

Also Published As

Publication number Publication date
BR0112773A (pt) 2003-06-24
HUP0301503A2 (en) 2003-08-28
ATE297370T1 (de) 2005-06-15
EP1303475B1 (de) 2005-06-08
EE200300038A (et) 2004-10-15
US6965029B2 (en) 2005-11-15
US20040030178A1 (en) 2004-02-12
JP2004505104A (ja) 2004-02-19
AU2001287635A1 (en) 2002-02-13
DE10036516A1 (de) 2002-02-07
ES2241866T3 (es) 2005-11-01
WO2002010113A1 (de) 2002-02-07
EP1303475A1 (de) 2003-04-23
PL358717A1 (en) 2004-08-09
CA2417269A1 (en) 2003-01-24
DE50106461D1 (de) 2005-07-14
CZ2003191A3 (cs) 2003-04-16

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