DE602004015310D1 - Verfahren zur herstellung von mycophenolatmofetil - Google Patents

Verfahren zur herstellung von mycophenolatmofetil

Info

Publication number
DE602004015310D1
DE602004015310D1 DE602004015310T DE602004015310T DE602004015310D1 DE 602004015310 D1 DE602004015310 D1 DE 602004015310D1 DE 602004015310 T DE602004015310 T DE 602004015310T DE 602004015310 T DE602004015310 T DE 602004015310T DE 602004015310 D1 DE602004015310 D1 DE 602004015310D1
Authority
DE
Germany
Prior art keywords
mycophenolate mofetil
production
products
relates
dimeric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602004015310T
Other languages
English (en)
Inventor
Julia Greil
Johannes Ludescher
Siegfried Wolf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of DE602004015310D1 publication Critical patent/DE602004015310D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE602004015310T 2003-09-11 2004-09-10 Verfahren zur herstellung von mycophenolatmofetil Active DE602004015310D1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AT14332003 2003-09-11
AT20302003 2003-12-17
AT20292003 2003-12-17
PCT/EP2004/010134 WO2005023791A2 (en) 2003-09-11 2004-09-10 Process for the production of mycophenolate mofetil

Publications (1)

Publication Number Publication Date
DE602004015310D1 true DE602004015310D1 (de) 2008-09-04

Family

ID=34279103

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602004015310T Active DE602004015310D1 (de) 2003-09-11 2004-09-10 Verfahren zur herstellung von mycophenolatmofetil

Country Status (8)

Country Link
US (1) US20070032483A1 (de)
EP (1) EP1667987B1 (de)
AT (1) ATE402157T1 (de)
CA (1) CA2537958C (de)
DE (1) DE602004015310D1 (de)
ES (1) ES2308226T3 (de)
PL (1) PL1667987T3 (de)
WO (1) WO2005023791A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7683188B2 (en) * 2004-04-26 2010-03-23 TEVA Gyógyszergyár Zártkōrūen Mūkōdō Részvénytársaság Process for preparation of mycophenolic acid and ester derivatives thereof
DE602007004728D1 (de) * 2006-06-29 2010-03-25 Ivax Pharmaceuticals Sro Regulation der säuremetabolitproduktion
WO2008003637A2 (en) * 2006-07-05 2008-01-10 Dsm Ip Assets B.V. Isolation and use of amine salts of mycophenolic acid
US20080188653A1 (en) 2007-02-04 2008-08-07 Formosa Laboratories, Inc. Process for Preparation of Mycophenolate Mofetil
TW200904982A (en) * 2007-04-11 2009-02-01 Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag Method for reducing impurity level in mycophenolic acid fermentation
WO2009040828A1 (en) * 2007-09-25 2009-04-02 Biocon Limited A process for purification of mycophenolic acid

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1173942A (en) * 1967-06-06 1969-12-10 Bellon Labor Sa Roger New 2,3-Dihydro-1,4-Benzoxazines
JPS5542995B2 (de) * 1972-02-24 1980-11-04
US3868454A (en) * 1972-08-14 1975-02-25 Lilly Co Eli Psoriasis treatment with mycophenolic acid derivatives
US3880995A (en) * 1973-05-14 1975-04-29 Lilly Co Eli Treatment of arthritis with mycophenolic acid and derivatives
US4686234A (en) * 1985-11-27 1987-08-11 Syntex (U.S.A) Inc. Mycophenolic acid derivatives in the treatment of inflammatory diseases, in particular rheumatoid arthritis
US4727069A (en) * 1987-01-30 1988-02-23 Syntex (U.S.A.) Inc. Heterocyclic aminoalkyl esters of mycophenolic acid, derivatives thereof and pharmaceutical compositions
US4753935A (en) * 1987-01-30 1988-06-28 Syntex (U.S.A.) Inc. Morpholinoethylesters of mycophenolic acid and pharmaceutical compositions
US4748173A (en) * 1987-01-30 1988-05-31 Syntex (U.S.A.) Inc. Heterocyclic aminoalkyl esters of mycophenolic acid and derivatives thereof and pharmaceutical compositions
US5247083A (en) * 1992-07-10 1993-09-21 Syntex (U.S.A.) Inc. Direct esterification of mycophenolic acid
JP3411038B2 (ja) * 1993-09-15 2003-05-26 シンテックス（ユー・エス・エイ）・インコーポレイテッド ミコフェノール酸モフェチルの結晶質無水物およびその静注用製剤
US5493030A (en) * 1994-02-18 1996-02-20 Syntex (U.S.A.) Inc. 5-substituted derivatives of mycophenolic acid
IN188985B (de) * 1998-12-09 2002-11-30 Biocon Ltd
CZ292123B6 (cs) * 2001-06-08 2003-08-13 Ivax Pharmaceuticals S.R.O. Způsob přípravy mykofenolátu mofetilu
CN1662496A (zh) * 2002-06-19 2005-08-31 先灵公司 大麻素受体激动剂

Also Published As

Publication number Publication date
PL1667987T3 (pl) 2009-01-30
EP1667987A2 (de) 2006-06-14
CA2537958C (en) 2013-06-11
ATE402157T1 (de) 2008-08-15
US20070032483A1 (en) 2007-02-08
CA2537958A1 (en) 2005-03-17
EP1667987B1 (de) 2008-07-23
ES2308226T3 (es) 2008-12-01
WO2005023791A3 (en) 2005-11-17
WO2005023791A2 (en) 2005-03-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336

8328 Change in the person/name/address of the agent

Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN