PT1212315E - Novas calconas - Google Patents

Novas calconas

Info

Publication number
PT1212315E
PT1212315E PT00964042T PT00964042T PT1212315E PT 1212315 E PT1212315 E PT 1212315E PT 00964042 T PT00964042 T PT 00964042T PT 00964042 T PT00964042 T PT 00964042T PT 1212315 E PT1212315 E PT 1212315E
Authority
PT
Portugal
Prior art keywords
calconas
new
medicament
prevention
manufacture
Prior art date
Application number
PT00964042T
Other languages
English (en)
Portuguese (pt)
Inventor
Ezio Bompardelli
Piero Valenti
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Publication of PT1212315E publication Critical patent/PT1212315E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/80Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82Xanthenes
    • C07D311/84Xanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
    • C07D311/86Oxygen atoms, e.g. xanthones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT00964042T 1999-09-03 2000-08-28 Novas calconas PT1212315E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9920910.8A GB9920910D0 (en) 1999-09-03 1999-09-03 Novel chalcones

Publications (1)

Publication Number Publication Date
PT1212315E true PT1212315E (pt) 2003-08-29

Family

ID=10860346

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00964042T PT1212315E (pt) 1999-09-03 2000-08-28 Novas calconas

Country Status (21)

Country Link
US (1) US6620842B2 (enExample)
EP (1) EP1212315B1 (enExample)
JP (1) JP2003508527A (enExample)
KR (1) KR100819576B1 (enExample)
CN (1) CN1177843C (enExample)
AT (1) ATE235483T1 (enExample)
AU (1) AU776226B2 (enExample)
CA (1) CA2382130A1 (enExample)
CZ (1) CZ2002787A3 (enExample)
DE (1) DE60001851T2 (enExample)
DK (1) DK1212315T3 (enExample)
ES (1) ES2193106T3 (enExample)
GB (1) GB9920910D0 (enExample)
HK (1) HK1043999B (enExample)
HU (1) HUP0202579A3 (enExample)
NO (1) NO20021049L (enExample)
PL (1) PL353064A1 (enExample)
PT (1) PT1212315E (enExample)
RU (1) RU2252938C2 (enExample)
SK (1) SK3112002A3 (enExample)
WO (1) WO2001017988A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003088903A2 (en) 2002-04-17 2003-10-30 Cytokinetics, Inc. Compounds, compositions, and methods
US7638554B2 (en) * 2002-04-18 2009-12-29 Sri International Flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents
US20030229136A1 (en) * 2002-04-18 2003-12-11 Nurulain Zaveri Novel flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents
DE60326248D1 (de) 2002-07-17 2009-04-02 Cytokinetics Inc Verbindungen, zusammensetzungen und verfahren zur behandlung von zellulären proliferativen erkrankungen
US6864264B1 (en) 2002-08-20 2005-03-08 Gloria L. Anderson 1-adamantyl chalcones for the treatment of proliferative disorders
CN100336797C (zh) * 2005-08-19 2007-09-12 浙江大学 四取代查耳酮衍生物及制备方法和用途
WO2013127361A1 (en) * 2012-03-01 2013-09-06 The Hong Kong Polytechnic University Alkyne-, azide- and triazole-containing flavonoids as modulators for multidrug resistance in cancers

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04502322A (ja) * 1988-12-21 1992-04-23 ジ・アップジョン・カンパニー 抗アテローム性動脈硬化症性および抗血栓性1―ベンゾピラン―4―オン類および2―アミノ―1,3―ベンゾオキサジン―4―オン類
US5023341A (en) * 1989-09-19 1991-06-11 Allergan, Inc. Compounds having a disubstituted acetylene moiety and retinoic acid-like biological activity
US4996230A (en) * 1990-02-16 1991-02-26 Eli Lilly And Company Leukotriene antagonists
JPH05509078A (ja) * 1990-05-17 1993-12-16 ベイラー カレッジ オブ メディシン 成長抑制因とガンおよび細胞増殖性疾患措置法
IT1271301B (it) * 1994-12-20 1997-05-27 Indena Spa Calconi naturali e sintetici e loro esteri ad attivita' antiproliferativa nei tumori dell'utero,dell'ovaio e del seno e formulazioni che li contengono
US5525625A (en) * 1995-01-24 1996-06-11 Warner-Lambert Company 2-(2-Amino-3-methoxyphenyl)-4-oxo-4H-[1]benzopyran for treating proliferative disorders

Also Published As

Publication number Publication date
ATE235483T1 (de) 2003-04-15
AU7510900A (en) 2001-04-10
DE60001851D1 (de) 2003-04-30
ES2193106T3 (es) 2003-11-01
AU776226B2 (en) 2004-09-02
HUP0202579A2 (hu) 2002-11-28
JP2003508527A (ja) 2003-03-04
EP1212315B1 (en) 2003-03-26
NO20021049L (no) 2002-05-03
CN1371372A (zh) 2002-09-25
US20030055056A1 (en) 2003-03-20
DK1212315T3 (da) 2003-06-23
SK3112002A3 (en) 2003-10-07
NO20021049D0 (no) 2002-03-01
WO2001017988A1 (en) 2001-03-15
GB9920910D0 (en) 1999-11-10
HUP0202579A3 (en) 2003-07-28
RU2252938C2 (ru) 2005-05-27
PL353064A1 (en) 2003-10-06
US6620842B2 (en) 2003-09-16
KR20020031598A (ko) 2002-05-02
CZ2002787A3 (cs) 2002-06-12
EP1212315A1 (en) 2002-06-12
HK1043999A1 (en) 2002-10-04
CN1177843C (zh) 2004-12-01
DE60001851T2 (de) 2003-12-11
HK1043999B (en) 2003-08-15
KR100819576B1 (ko) 2008-04-22
CA2382130A1 (en) 2001-03-15

Similar Documents

Publication Publication Date Title
EP1233770A4 (en) PHOSPHONATE COMPOUNDS
PL367682A1 (en) Dolastatin 10 derivatives
ATE303359T1 (de) Biphenylverbindungen und biphenyl-analoge als intergrin-antagonisten
TR200003735T2 (tr) Osteoporoz ve menopoz sendromuna bağlı rahatsızlıkların önlenmesi ve tedavileri
TNSN05045A1 (en) Indole or benzimidazole derivatives for modulating ikappab kinase
MY141661A (en) 17b-hydroxysteroid dehydrogenase type 3 inhibitors for the treatment of androgen dependent diseases
ATE236147T1 (de) Derivate von flavonen, xanthonen und kumarinen
MXPA04004674A (es) Ligados de los receptors de los canabinodies.
MY128659A (en) Novel aminodicarboxylic acid derivatives having pharmaceutical properties
TR200101969T2 (tr) Enflamasyon tedavisi için sübstitüe edilmiş benzopiran analogları.
GB0225475D0 (en) Therapeutic agents
MY140080A (en) Treatment and prevention of osteoporosis
MXPA04003087A (es) Derivados de cromano como ligados de 5-hidroxitriptamina-6.
ATE241641T1 (de) Betulinsäure derivate zur behandlung von neuroektodermalen tumoren
AP2000001898A0 (en) Vitronectin receptor antagonists
UA72948C2 (uk) Заміщені похідні фенілпіперазину, фармацевтична композиція та спосіб лікування афективних або неврологічних захворювань і розладів
DK0989973T3 (da) Chalconer med antiproliferativ aktivitet
PT1212315E (pt) Novas calconas
BR9917495A (pt) Derivados o ácido betulìnico tendo atividade antiangiogênica, processos para produzir tais derivados e sua utilização para o tratamento de antiogênese associada a tumores
NO20014241D0 (no) C16-umettede FP-selektive prostaglandinanaloger
AP9801202A0 (en) Atropisomers of 3-heteroaryl-4(3H)-quinazolinones.
DE69917005D1 (de) Substituierte pyrrolobenzimidazolderivate zur entzündungshemmung
MXPA04000805A (es) Peptidos que tienen actividad antiangiogenica.
ATE346036T1 (de) Antiangiogene substanz zur behandlung von krebs, arthritis und netzhauterkrankungen
IT1289154B1 (it) Derivati di isoflavone loro preparazione e loro impiego terapeutico