PT1169021E - Composições e métodos para o tratamento de linfoma - Google Patents

Composições e métodos para o tratamento de linfoma Download PDF

Info

Publication number
PT1169021E
PT1169021E PT00920004T PT00920004T PT1169021E PT 1169021 E PT1169021 E PT 1169021E PT 00920004 T PT00920004 T PT 00920004T PT 00920004 T PT00920004 T PT 00920004T PT 1169021 E PT1169021 E PT 1169021E
Authority
PT
Portugal
Prior art keywords
mol
compositions
methods
cholesterol
lymphoma
Prior art date
Application number
PT00920004T
Other languages
English (en)
Inventor
Andreas H Sarris
Fernando Cabanillas
Patricia M Logan
Clive T R Burge
James H Goldie
Murray S Webb
Mayer D Lawrence
Original Assignee
Univ Texas
Hana Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas, Hana Biosciences Inc filed Critical Univ Texas
Publication of PT1169021E publication Critical patent/PT1169021E/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/475Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
PT00920004T 1999-04-01 2000-03-31 Composições e métodos para o tratamento de linfoma PT1169021E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12744499P 1999-04-01 1999-04-01
US13719499P 1999-06-02 1999-06-02

Publications (1)

Publication Number Publication Date
PT1169021E true PT1169021E (pt) 2009-11-18

Family

ID=26825635

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00920004T PT1169021E (pt) 1999-04-01 2000-03-31 Composições e métodos para o tratamento de linfoma

Country Status (14)

Country Link
EP (3) EP2266537B1 (pt)
JP (3) JP2002541088A (pt)
AT (1) ATE442839T1 (pt)
AU (1) AU777572B2 (pt)
BR (1) BRPI0009448B8 (pt)
CA (1) CA2366787C (pt)
CY (1) CY1109641T1 (pt)
DE (1) DE60042968D1 (pt)
DK (2) DK1169021T3 (pt)
ES (2) ES2524141T3 (pt)
HK (1) HK1152246A1 (pt)
IL (4) IL145720A0 (pt)
PT (1) PT1169021E (pt)
WO (1) WO2000059473A1 (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2266537B1 (en) * 1999-04-01 2014-09-03 Hana Biosciences, Inc. Compositions for treating cancer
US6723338B1 (en) 1999-04-01 2004-04-20 Inex Pharmaceuticals Corporation Compositions and methods for treating lymphoma
EP1229934B1 (en) 1999-10-01 2014-03-05 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
US7303749B1 (en) 1999-10-01 2007-12-04 Immunogen Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
GB0000313D0 (en) 2000-01-10 2000-03-01 Astrazeneca Uk Ltd Formulation
US7097840B2 (en) 2000-03-16 2006-08-29 Genentech, Inc. Methods of treatment using anti-ErbB antibody-maytansinoid conjugates
ES2332584T3 (es) * 2001-03-27 2010-02-09 Phares Pharmaceutical Research N.V. Metodo y composicion para solubilizar un compuesto biologicamente activo con baja solubilidad en agua.
EP2561874A3 (en) * 2002-05-17 2013-09-04 Celgene Corporation Pharmaceutical compositions for treating cancer
FR2840203B1 (fr) * 2002-05-31 2004-08-27 Scherer Technologies Inc R P Composition pharmaceutique orale pour capsules molles contenant vinorelbine et methode de traitement
US6890558B2 (en) 2002-05-31 2005-05-10 R.P. Scherer Technologies, Inc. Oral pharmaceutical composition for soft capsules containing vinorelbine and method of treatment
US7563810B2 (en) * 2002-11-06 2009-07-21 Celgene Corporation Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases
US8088387B2 (en) 2003-10-10 2012-01-03 Immunogen Inc. Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
WO2005011698A1 (en) * 2003-07-28 2005-02-10 Inex Pharmaceuticals Corporation Combination comprising a liposome-encapsulated vinca alkaloid and a topoisomerase ii inhibitor and the use thereof for treating neoplasia
KR101250127B1 (ko) * 2004-07-09 2013-04-02 바이엘 파마 악티엔게젤샤프트 B-세포 림프종의 치료를 위한 방사성표지된 안티-cd20항체와의 병용요법
ES2382337T3 (es) * 2004-08-10 2012-06-07 Talon Therapeutics, Inc. Composiciones y procedimientos para tratar la leucemia
SI2200431T1 (sl) * 2007-09-10 2016-10-28 Boston Biomedical, Inc. Sestave in metode za zdravljenje raka
TWI574698B (zh) 2008-03-18 2017-03-21 建南德克公司 抗her2抗體-藥物結合物及化療劑之組合及使用方法
WO2010047714A1 (en) * 2008-10-24 2010-04-29 Gloucester Pharmaceuticals Cancer therapy
EP2922529B1 (en) 2012-11-20 2019-03-13 Spectrum Pharmaceuticals, Inc. Improved method for the preparation of liposome encapsulated vincristine for therapeutic use
EP2948132B1 (en) * 2013-01-24 2020-08-19 Memorial Sloan Kettering Cancer Center Method for diagnosing or treating tumors using sphingomyelin containing liposomes
AU2014250940A1 (en) 2013-04-09 2015-10-22 Boston Biomedical, Inc. 2-acetylnaphtho[2,3-b]furan -4,9-dione for use on treating cancer
TWI678213B (zh) * 2015-07-22 2019-12-01 美商史倍壯製藥公司 用於長春新鹼硫酸鹽脂質體注射之即可使用的調配物
CA3045306A1 (en) 2016-11-29 2018-06-07 Boston Biomedical, Inc. Naphthofuran derivatives, preparation, and methods of use thereof
JP2020520923A (ja) 2017-05-17 2020-07-16 ボストン バイオメディカル, インコーポレイテッド がんを処置するための方法

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4217344A (en) 1976-06-23 1980-08-12 L'oreal Compositions containing aqueous dispersions of lipid spheres
US4235871A (en) 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4186183A (en) 1978-03-29 1980-01-29 The United States Of America As Represented By The Secretary Of The Army Liposome carriers in chemotherapy of leishmaniasis
US4261975A (en) 1979-09-19 1981-04-14 Merck & Co., Inc. Viral liposome particle
US4485054A (en) 1982-10-04 1984-11-27 Lipoderm Pharmaceuticals Limited Method of encapsulating biologically active materials in multilamellar lipid vesicles (MLV)
US4501728A (en) 1983-01-06 1985-02-26 Technology Unlimited, Inc. Masking of liposomes from RES recognition
US4603044A (en) 1983-01-06 1986-07-29 Technology Unlimited, Inc. Hepatocyte Directed Vesicle delivery system
US5077056A (en) 1984-08-08 1991-12-31 The Liposome Company, Inc. Encapsulation of antineoplastic agents in liposomes
US5736155A (en) 1984-08-08 1998-04-07 The Liposome Company, Inc. Encapsulation of antineoplastic agents in liposomes
US4946787A (en) 1985-01-07 1990-08-07 Syntex (U.S.A.) Inc. N-(ω,(ω-1)-dialkyloxy)- and N-(ω,(ω-1)-dialkenyloxy)-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor
US5059421A (en) 1985-07-26 1991-10-22 The Liposome Company, Inc. Preparation of targeted liposome systems of a defined size distribution
US4885172A (en) 1985-06-26 1989-12-05 The Liposome Company, Inc. Composition for targeting, storing and loading of liposomes
US5171578A (en) 1985-06-26 1992-12-15 The Liposome Company, Inc. Composition for targeting, storing and loading of liposomes
US4774085A (en) 1985-07-09 1988-09-27 501 Board of Regents, Univ. of Texas Pharmaceutical administration systems containing a mixture of immunomodulators
US4737323A (en) 1986-02-13 1988-04-12 Liposome Technology, Inc. Liposome extrusion method
US4837028A (en) 1986-12-24 1989-06-06 Liposome Technology, Inc. Liposomes with enhanced circulation time
US4952408A (en) * 1988-05-23 1990-08-28 Georgetown University Liposome-encapsulated vinca alkaloids and their use in combatting tumors
US4957773A (en) 1989-02-13 1990-09-18 Syracuse University Deposition of boron-containing films from decaborane
AU7979491A (en) 1990-05-03 1991-11-27 Vical, Inc. Intracellular delivery of biologically active substances by means of self-assembling lipid complexes
US5165922A (en) * 1990-05-22 1992-11-24 Bristol-Myers Squibb Company Synergistic tumor therapy with combinations of biologically active anti-tumor antibodies and chemotherapy
GB9304745D0 (en) * 1993-03-09 1993-04-28 Oncholab Ab Use of pharmaceutical formulations
US5595756A (en) * 1993-12-22 1997-01-21 Inex Pharmaceuticals Corporation Liposomal compositions for enhanced retention of bioactive agents
US5543152A (en) * 1994-06-20 1996-08-06 Inex Pharmaceuticals Corporation Sphingosomes for enhanced drug delivery
US5741516A (en) 1994-06-20 1998-04-21 Inex Pharmaceuticals Corporation Sphingosomes for enhanced drug delivery
US5714163A (en) * 1994-06-27 1998-02-03 Nexstar Pharmaceuticals, Inc. Vinca alkaloid vesicles with enhanced efficacy and tumor targeting properties
US5885613A (en) 1994-09-30 1999-03-23 The University Of British Columbia Bilayer stabilizing components and their use in forming programmable fusogenic liposomes
US5820873A (en) 1994-09-30 1998-10-13 The University Of British Columbia Polyethylene glycol modified ceramide lipids and liposome uses thereof
US5837282A (en) 1996-10-30 1998-11-17 University Of British Columbia Ionophore-mediated liposome loading
US6320017B1 (en) 1997-12-23 2001-11-20 Inex Pharmaceuticals Corp. Polyamide oligomers
EP2266537B1 (en) * 1999-04-01 2014-09-03 Hana Biosciences, Inc. Compositions for treating cancer

Also Published As

Publication number Publication date
ATE442839T1 (de) 2009-10-15
JP2012158602A (ja) 2012-08-23
CA2366787C (en) 2013-03-12
EP2266537B1 (en) 2014-09-03
IL212390A0 (en) 2011-06-30
BRPI0009448B8 (pt) 2021-05-25
IL212390A (en) 2014-08-31
IL145720A (en) 2011-05-31
CY1109641T1 (el) 2014-08-13
AU4060600A (en) 2000-10-23
ES2333400T3 (es) 2010-02-22
EP1169021A1 (en) 2002-01-09
BR0009448A (pt) 2002-01-08
HK1152246A1 (en) 2012-02-24
EP2266537A2 (en) 2010-12-29
EP1985285A2 (en) 2008-10-29
DK2266537T3 (en) 2014-12-15
IL145720A0 (en) 2002-07-25
JP2002541088A (ja) 2002-12-03
AU777572B2 (en) 2004-10-21
IL212389A (en) 2015-07-30
DE60042968D1 (de) 2009-10-29
IL212389A0 (en) 2011-06-30
EP2266537A3 (en) 2012-02-22
DK1169021T3 (da) 2010-01-11
BRPI0009448B1 (pt) 2018-09-11
WO2000059473A1 (en) 2000-10-12
EP1985285A3 (en) 2009-08-12
EP1169021B1 (en) 2009-09-16
JP2015071631A (ja) 2015-04-16
JP5981214B2 (ja) 2016-08-31
CA2366787A1 (en) 2000-10-12
ES2524141T3 (es) 2014-12-04

Similar Documents

Publication Publication Date Title
HK1152246A1 (en) Compositions for treating cancer
HK1023064A1 (en) Method of inhibiting bacterial or fungal growth using a complexing agent
MX9603570A (es) Metodo y composiciones para incrementar la vida media en suero de agentes farmacologicamente activos.
WO1999043355A3 (en) Formulations containing oxaliplatin
SG47520A1 (en) New method for the production of 9-amino-6-demethyl-6-deoxytetracycline
IL136044A (en) 2-aminoacetamide derivatives and pharmaceutical compositions containing the same
AP9701019A0 (en) Phenylamino-substituted tricycle derivatives.
PL319833A1 (en) Compounds and composition for carrying active media
HK1039328B (zh) 用於治療陽痿的吡唑並嘧啶酮衍生物
BG103310A (en) Benzonaphthyridins as bronchial therapeutical means
PL338181A1 (en) Novel chemical compounds
HK1085675A1 (en) Anticancer compounds
IL133824A (en) Tetrazole derivatives and medicaments containing the same
WO2003051275A3 (en) Benzodiazepine derivatives, preparation thereof and use thereof
WO1999063976A3 (en) Liver-selective glucocorticoid antagonist for treating diabetes
GB0028323D0 (en) Tetrahydrofuran-adducted group 11 ›-diketonate complexes as source reagents for chemical vapor depostion
NZ319138A (en) Composition containing cytochrome complex III and fenazaquin for combatting parasitic fungi
AU695749B2 (en) Functional terpyridine metal complexes, a process for the preparation therof and oligonucleotide conjugates with terpyridine-metal complexes
WO1998003519A3 (en) New bis-platinum complexes with polyamine ligands as antitumor agents
WO2000076989A3 (de) Verfahren zur umsetzung organischer verbindungen mit wasserstoffperoxid
ES2173464T3 (es) Preparacion de clorinas y bacterioclorinas con contenido en polieter.
IL114646A0 (en) Method of inhibiting leukotriene biosynthesis
EP1057832A4 (en) SUBSTANCE HAVING A STEROID-LIKE STRUCTURE, METHOD FOR THE PRODUCTION THEREOF, AND ANTI-TUMOR AGENTS CONTAINING THE SAME
UA70975C2 (uk) Похідні 1,4-діарил-2-фтор-1-бутен-3-олу, спосіб їх одержання та способи одержання похідних 1,4-діарил-2-фтор-1,3-бутадієну і 1,4-діарил-2-фтор-2-бутену
HU9903046D0 (en) Cpmplex compound useful in treating iron deficiency, pharmaceutical composition containing same, and process for producing same