PT1140019E - Formulacoes em aerosol para aplicacao bucal e pulmonar - Google Patents

Formulacoes em aerosol para aplicacao bucal e pulmonar

Info

Publication number
PT1140019E
PT1140019E PT99962009T PT99962009T PT1140019E PT 1140019 E PT1140019 E PT 1140019E PT 99962009 T PT99962009 T PT 99962009T PT 99962009 T PT99962009 T PT 99962009T PT 1140019 E PT1140019 E PT 1140019E
Authority
PT
Portugal
Prior art keywords
aerosol
bucal
formulations
pulmonary application
propellant
Prior art date
Application number
PT99962009T
Other languages
English (en)
Portuguese (pt)
Inventor
Pankaj Modi
Original Assignee
Generex Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/251,464 external-priority patent/US6436367B1/en
Application filed by Generex Pharm Inc filed Critical Generex Pharm Inc
Publication of PT1140019E publication Critical patent/PT1140019E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Physiology (AREA)
  • Hematology (AREA)
  • Otolaryngology (AREA)
  • Dispersion Chemistry (AREA)
  • Nutrition Science (AREA)
  • Biophysics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Emergency Medicine (AREA)
  • AIDS & HIV (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
PT99962009T 1998-12-21 1999-12-16 Formulacoes em aerosol para aplicacao bucal e pulmonar PT1140019E (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11323998P 1998-12-21 1998-12-21
US09/251,464 US6436367B1 (en) 1998-12-21 1999-02-17 Aerosol formulations for buccal and pulmonary application
US09/386,284 US6312665B1 (en) 1998-12-21 1999-08-31 Aerosol formulations for buccal and pulmonary application

Publications (1)

Publication Number Publication Date
PT1140019E true PT1140019E (pt) 2003-10-31

Family

ID=27381295

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99962009T PT1140019E (pt) 1998-12-21 1999-12-16 Formulacoes em aerosol para aplicacao bucal e pulmonar

Country Status (13)

Country Link
US (1) US6312665B1 (https=)
EP (1) EP1140019B1 (https=)
JP (1) JP3818851B2 (https=)
AT (1) ATE243498T1 (https=)
AU (1) AU760445B2 (https=)
CA (1) CA2354148C (https=)
DE (1) DE69909127T2 (https=)
DK (1) DK1140019T3 (https=)
ES (1) ES2203227T3 (https=)
MX (1) MXPA01006380A (https=)
NZ (1) NZ512188A (https=)
PT (1) PT1140019E (https=)
WO (1) WO2000037051A1 (https=)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2686899B1 (fr) 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
US6221378B1 (en) * 1998-02-10 2001-04-24 Generex Pharmaceuticals Incorporated Mixed micellar delivery system and method of preparation
US7087215B2 (en) * 1998-12-21 2006-08-08 Generex Pharmaceuticals Incorporated Methods of administering and enhancing absorption of pharmaceutical agents
US6375975B1 (en) * 1998-12-21 2002-04-23 Generex Pharmaceuticals Incorporated Pharmaceutical compositions for buccal and pulmonary application
US6849263B2 (en) 1998-12-21 2005-02-01 Generex Pharmaceutical Incorporated Pharmaceutical compositions for buccal delivery of pain relief medications
US6451286B1 (en) * 1998-12-21 2002-09-17 Generex Pharmaceuticals Incorporated Pharmaceutical compositions for buccal and pulmonary administration comprising an alkali metal alkyl sulfate and at least three micelle-forming compounds
WO2001072278A2 (en) * 2000-03-30 2001-10-04 Generex Pharmaceuticals Inc. Method for administering insulin to the buccal region
EP2206720A1 (en) 2000-04-12 2010-07-14 Human Genome Sciences, Inc. Albumin fusion proteins
EP2261250B1 (en) 2001-12-21 2015-07-01 Human Genome Sciences, Inc. GCSF-Albumin fusion proteins
CA2666005C (en) 2002-03-01 2016-01-19 Dyax Corp. Kdr and vegf/kdr binding peptides and their use in diagnosis and therapy
US7261876B2 (en) 2002-03-01 2007-08-28 Bracco International Bv Multivalent constructs for therapeutic and diagnostic applications
US20050100963A1 (en) 2002-03-01 2005-05-12 Dyax Corporation KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
US8623822B2 (en) 2002-03-01 2014-01-07 Bracco Suisse Sa KDR and VEGF/KDR binding peptides and their use in diagnosis and therapy
US7794693B2 (en) 2002-03-01 2010-09-14 Bracco International B.V. Targeting vector-phospholipid conjugates
US7211240B2 (en) 2002-03-01 2007-05-01 Bracco International B.V. Multivalent constructs for therapeutic and diagnostic applications
WO2003097094A1 (en) * 2002-05-21 2003-11-27 Anadis Ltd Method of prophylaxis of infection
EP1369113B1 (en) * 2002-06-06 2006-11-22 CHIESI FARMACEUTICI S.p.A. Solubilisation of drugs in HFA propellant by means of emulsions
CA2502118A1 (en) * 2002-10-11 2004-05-06 Sanwa Kagaku Kenkyusho Co., Ltd. Glp-1 derivatives and transmicosal absorption preparations thereof
AU2003291872A1 (en) * 2002-12-04 2004-06-23 Inrs (Institut National De Recherche Scientifique) An exopolysaccharides delivery system for active molecules
DE10260882B4 (de) * 2002-12-24 2007-02-08 IG Sprühtechnik GmbH & Co. KG Dosieraerosole mit Sojalecithin als oberflächenaktiver Substanz und dessen Verwendung
CA2513213C (en) 2003-01-22 2013-07-30 Human Genome Sciences, Inc. Albumin fusion proteins
PT2949658T (pt) 2003-03-03 2018-10-18 Bracco Suisse Sa Péptidos que ligam especificamente o recetor de hgf (cmet) e utilizações dos mesmos
US20050238632A1 (en) * 2004-04-23 2005-10-27 Alburty David S Propellant formulations
PE20061245A1 (es) * 2005-03-30 2007-01-06 Generex Pharm Inc Composiciones para la transmision transmucosa oral de la metformina
CN101309668A (zh) * 2005-11-30 2008-11-19 健乐克斯医药公司 经口吸收的药物制剂和用药方法
US20080085331A1 (en) * 2006-10-06 2008-04-10 Gluskin Anna E Composition and method for raising blood glucose level
BR112012012945A2 (pt) 2009-11-25 2020-12-29 Arisgen Sa Composição de liberação mucosal, seu método de produção, complexo de peptídeo pré-formado, kit e uso de um agente ativo de peptídeo
US20130269684A1 (en) 2012-04-16 2013-10-17 Dance Pharmaceuticals, Inc. Methods and systems for supplying aerosolization devices with liquid medicaments
US9545488B2 (en) 2010-01-12 2017-01-17 Dance Biopharm Inc. Preservative-free single dose inhaler systems
US10525214B2 (en) 2010-01-12 2020-01-07 Dance Biopharm Inc. Preservative-free single dose inhaler system
US8950394B2 (en) 2010-01-12 2015-02-10 Dance Biopharm Inc. Preservative-free single dose inhaler systems
US9180261B2 (en) 2010-01-12 2015-11-10 Dance Biopharm Inc. Preservative free insulin formulations and systems and methods for aerosolizing
US10842951B2 (en) 2010-01-12 2020-11-24 Aerami Therapeutics, Inc. Liquid insulin formulations and methods relating thereto
EP2526971A1 (en) 2011-05-25 2012-11-28 ArisGen SA Mucosal delivery of drugs
US10610512B2 (en) 2014-06-26 2020-04-07 Island Breeze Systems Ca, Llc MDI related products and methods of use
US11273271B2 (en) 2014-07-01 2022-03-15 Aerami Therapeutics, Inc. Aerosolization system with flow restrictor and feedback device
US10471222B2 (en) 2014-07-01 2019-11-12 Dance Biopharm Inc. Aerosolization system with flow restrictor and feedback device
US10857313B2 (en) 2014-07-01 2020-12-08 Aerami Therapeutics, Inc. Liquid nebulization systems and methods
EP3261648B1 (en) 2015-02-25 2023-12-06 Aerami Therapeutics, Inc. Liquid insulin formulations and methods relating thereto
US11166912B2 (en) 2016-03-03 2021-11-09 Ctt Pharma Inc. Orally administrable composition
CA3026108A1 (en) 2016-06-10 2017-12-14 Clarity Cosmetics Inc. Non-comedogenic hair and scalp care formulations and method for use
CN109568267B (zh) * 2018-12-28 2021-01-05 中山市天图精细化工有限公司 一种冰冻镇痛气雾剂及其制备方法
US11298336B2 (en) 2019-05-30 2022-04-12 Soluble Technologies, Inc. Water soluble formulation
US11786475B2 (en) 2020-07-22 2023-10-17 Soluble Technologies Inc. Film-based dosage form
KR102882807B1 (ko) * 2021-07-16 2025-11-10 주식회사 닥스메디 레시틴 효소반응물 및 이를 유효성분으로 포함하는 구강 건강 소재 및 제품

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0753661B2 (ja) 1984-03-08 1995-06-07 フアレス フアーマスーチカル リサーチ エヌブイ プロ―リポソーム組成物及びリポソームの水性分散物を作る方法
US4839111A (en) * 1987-02-02 1989-06-13 The University Of Tennessee Research Corporation Preparation of solid core liposomes
US5174988A (en) * 1989-07-27 1992-12-29 Scientific Development & Research, Inc. Phospholipid delivery system
US5653987A (en) * 1995-05-16 1997-08-05 Modi; Pankaj Liquid formulations for proteinic pharmaceuticals
PL323931A1 (en) 1995-06-07 1998-04-27 Alliance Pharma Compositions of reversed emulsion of fluorine derivatives of hydrocarbons for use as drug delivering carriers
US5891465A (en) 1996-05-14 1999-04-06 Biozone Laboratories, Inc. Delivery of biologically active material in a liposomal formulation for administration into the mouth
US6090407A (en) * 1997-09-23 2000-07-18 Research Development Foundation Small particle liposome aerosols for delivery of anti-cancer drugs
US6017545A (en) * 1998-02-10 2000-01-25 Modi; Pankaj Mixed micellar delivery system and method of preparation

Also Published As

Publication number Publication date
NZ512188A (en) 2002-10-25
ATE243498T1 (de) 2003-07-15
WO2000037051A1 (en) 2000-06-29
JP2002532536A (ja) 2002-10-02
DK1140019T3 (da) 2003-10-20
DE69909127T2 (de) 2004-04-08
JP3818851B2 (ja) 2006-09-06
US6312665B1 (en) 2001-11-06
AU1851800A (en) 2000-07-12
CA2354148C (en) 2010-11-23
EP1140019A1 (en) 2001-10-10
MXPA01006380A (es) 2002-04-24
ES2203227T3 (es) 2004-04-01
AU760445B2 (en) 2003-05-15
DE69909127D1 (de) 2003-07-31
CA2354148A1 (en) 2000-06-29
EP1140019B1 (en) 2003-06-25

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