PT1135460E - Metodo e dispositivo para a seleccao da proliferacao acelerada de celulas vivas em suspensao - Google Patents
Metodo e dispositivo para a seleccao da proliferacao acelerada de celulas vivas em suspensaoInfo
- Publication number
- PT1135460E PT1135460E PT99961053T PT99961053T PT1135460E PT 1135460 E PT1135460 E PT 1135460E PT 99961053 T PT99961053 T PT 99961053T PT 99961053 T PT99961053 T PT 99961053T PT 1135460 E PT1135460 E PT 1135460E
- Authority
- PT
- Portugal
- Prior art keywords
- culture
- suspension
- culture vessel
- organisms
- present
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/58—Reaction vessels connected in series or in parallel
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/813—Continuous fermentation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Clinical Laboratory Science (AREA)
- Molecular Biology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19856136A DE19856136C2 (de) | 1998-12-04 | 1998-12-04 | Verfahren und Vorrichtung zur Selektion beschleunigter Proliferation lebender Zellen in Suspension |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1135460E true PT1135460E (pt) | 2003-09-30 |
Family
ID=7890072
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT99961053T PT1135460E (pt) | 1998-12-04 | 1999-12-02 | Metodo e dispositivo para a seleccao da proliferacao acelerada de celulas vivas em suspensao |
Country Status (15)
Country | Link |
---|---|
US (1) | US6686194B1 (pt) |
EP (1) | EP1135460B1 (pt) |
JP (1) | JP4615722B2 (pt) |
AT (1) | ATE240388T1 (pt) |
AU (1) | AU779542B2 (pt) |
CA (1) | CA2358437C (pt) |
DE (2) | DE19856136C2 (pt) |
DK (1) | DK1135460T3 (pt) |
ES (1) | ES2193769T3 (pt) |
HK (1) | HK1039790B (pt) |
IL (2) | IL143300A0 (pt) |
MX (1) | MXPA01005523A (pt) |
NZ (1) | NZ511961A (pt) |
PT (1) | PT1135460E (pt) |
WO (1) | WO2000034433A1 (pt) |
Families Citing this family (55)
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AU2002330671B2 (en) * | 2001-07-06 | 2008-04-03 | Centre National De La Recherche Scientifique (Cnrs) | Method for obtaining cells with new properties |
US20040214314A1 (en) | 2001-11-02 | 2004-10-28 | Friedrich Srienc | High throughput bioreactor |
US20060270013A1 (en) | 2003-02-18 | 2006-11-30 | Michel Chateau | Method for the production of evolved microorganisms which permit the generation or modification of metabolic pathways |
FR2860510B1 (fr) * | 2003-10-01 | 2006-12-08 | Eco Solution | Procede et dispositif de culture de cellules vivantes par couplage d'un bioreacteur avec un automate de selection. |
BRPI0507983B1 (pt) * | 2004-02-23 | 2015-04-22 | Eudes François Marie De Crecy | Dispositivo e método que aumentam a taxa de reprodução de células vivas em suspensão ou de quaisquer organismos cultiváveis, incluíndo bactérias, archea, eucariotos, e vírus, pelo processo de seleção natural pela maior velocidade de reprodução e/ou maior rendimento reprodutivo |
US20070037276A1 (en) * | 2004-02-23 | 2007-02-15 | Eudes Francois Marie De Crecy | Continuous culture apparatus with mobile vessel, allowing selection of fitter cell variants and producing a culture in a continuous manner |
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CN103555643B (zh) * | 2008-03-27 | 2016-08-10 | 基因组股份公司 | 用于产生己二酸和其他化合物的微生物 |
BRPI0911759A2 (pt) | 2008-05-01 | 2019-09-24 | Genomatica Inc | microorganismo para a produção de ácido metacrílico |
WO2009155382A1 (en) * | 2008-06-17 | 2009-12-23 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of fumarate, malate, and acrylate |
US20110306101A1 (en) * | 2008-07-11 | 2011-12-15 | De Crecy Eudes | method of producing fatty acids for biofuel, biodiesel, and other valuable chemicals |
US20100021978A1 (en) * | 2008-07-23 | 2010-01-28 | Genomatica, Inc. | Methods and organisms for production of 3-hydroxypropionic acid |
WO2010057022A1 (en) * | 2008-11-14 | 2010-05-20 | Genomatica, Inc. | Microorganisms for the production of methyl ethyl ketone and 2-butanol |
KR20110097951A (ko) * | 2008-12-16 | 2011-08-31 | 게노마티카 인코포레이티드 | 합성가스와 다른 탄소원을 유용 제품으로 전환시키기 위한 미생물 및 방법 |
CA2797068A1 (en) * | 2009-04-29 | 2010-11-04 | Eudes De Crecy | Adapting microorganisms for agricultural products |
WO2010127303A1 (en) | 2009-04-30 | 2010-11-04 | Genomatica, Inc. | Organisms for the production of isopropanol, n-butanol, and isobutanol |
CN102625846B (zh) * | 2009-04-30 | 2016-08-03 | 基因组股份公司 | 用于生产1,3-丁二醇的生物 |
KR102099295B1 (ko) | 2009-05-07 | 2020-04-09 | 게노마티카 인코포레이티드 | 아디페이트, 헥사메틸렌디아민 및 6-아미노카프로산의 생합성을 위한 미생물 및 방법 |
KR20120036851A (ko) * | 2009-05-15 | 2012-04-18 | 게노마티카 인코포레이티드 | 사이클로헥사논의 제조를 위한 유기체 |
US8420375B2 (en) * | 2009-06-10 | 2013-04-16 | Genomatica, Inc. | Microorganisms and methods for carbon-efficient biosynthesis of MEK and 2-butanol |
US20110124911A1 (en) | 2009-08-05 | 2011-05-26 | Burk Mark J | Semi-synthetic terephthalic acid via microorganisms that produce muconic acid |
MX2012003025A (es) | 2009-09-09 | 2012-06-27 | Genomatica Inc | Microorganismos y metodos para la co-produccion de isopropanol con alcoholes, dioles y acidos primarios. |
JP2013507145A (ja) | 2009-10-13 | 2013-03-04 | ゲノマチカ, インク. | 1,4−ブタンジオール、4−ヒドロキシブタナール、4−ヒドロキシブチリル−CoA、プトレシン及び関連化合物の生成のための微生物体並びに関連する方法 |
BR112012009332A2 (pt) | 2009-10-23 | 2015-09-15 | Genomatica Inc | micro-organismo para a produção de anilina |
CN109136161A (zh) * | 2009-12-10 | 2019-01-04 | 基因组股份公司 | 合成气或其他气态碳源和甲醇转化为1,3-丁二醇的方法和有机体 |
US8647850B2 (en) | 2009-12-23 | 2014-02-11 | E I Du Pont De Nemours And Company | Process for simultaneous saccharification and fermentation for production of ethanol |
EP2529011A4 (en) | 2010-01-29 | 2015-07-15 | Genomatica Inc | MICROORGANISMS AND METHODS FOR BIOSYNTHESIS OF P-TOLUATE AND TEREPHTHALATE |
US8048661B2 (en) * | 2010-02-23 | 2011-11-01 | Genomatica, Inc. | Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes |
US8445244B2 (en) * | 2010-02-23 | 2013-05-21 | Genomatica, Inc. | Methods for increasing product yields |
US8906235B2 (en) | 2010-04-28 | 2014-12-09 | E I Du Pont De Nemours And Company | Process for liquid/solid separation of lignocellulosic biomass hydrolysate fermentation broth |
US8721794B2 (en) | 2010-04-28 | 2014-05-13 | E I Du Pont De Nemours And Company | Production of high solids syrup from lignocellulosic biomass hydrolysate fermentation broth |
US9023636B2 (en) | 2010-04-30 | 2015-05-05 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of propylene |
CA2797409C (en) | 2010-05-05 | 2019-12-24 | Genomatica, Inc. | Microorganisms and methods for the biosynthesis of butadiene |
BR112013001635A2 (pt) | 2010-07-26 | 2016-05-24 | Genomatica Inc | micro-organismo e métodos para a biossíntese de aromáticos, 2, 4-pentadienoato e 1,3-butadieno |
US8476048B2 (en) | 2010-12-17 | 2013-07-02 | E I Du Pont De Nemours And Company | Xylose utilizing zymomonas mobilis with improved ethanol production in biomass hydrolysate medium |
EP2855687B1 (en) | 2012-06-04 | 2020-04-22 | Genomatica, Inc. | Microorganisms and methods for production of 4-hydroxybutyrate, 1,4-butanediol and related compounds |
US9657316B2 (en) | 2012-08-27 | 2017-05-23 | Genomatica, Inc. | Microorganisms and methods for enhancing the availability of reducing equivalents in the presence of methanol, and for producing 1,4-butanediol related thereto |
CA2888197C (en) | 2012-10-15 | 2023-03-07 | Genomatica, Inc. | Microorganisms and methods for production of specific length fatty alcohols and related compounds |
US11535874B2 (en) | 2012-10-22 | 2022-12-27 | Genomatica, Inc. | Microorganisms and methods for enhancing the availability of reducing equivalents in the presence of methanol, and for producing succinate related thereto |
EP3862421A1 (en) | 2012-12-17 | 2021-08-11 | Genomatica, Inc. | Microorganisms and methods for enhancing the availability of reducing equivalents in the presence of methanol, and for producing adipate, 6-aminocaproate, hexamethylenediamine or caprolactam related thereto |
WO2014176514A2 (en) | 2013-04-26 | 2014-10-30 | Genomatica, Inc. | Microorganisms and methods for production of 4-hydroxybutyrate, 1,4-butanediol and related compounds |
US9499451B2 (en) | 2013-10-10 | 2016-11-22 | E I Du Pont De Nemours And Company | Soil conditioner compositions containing lignocellulosic biomass fermentation process syrup |
US20150104842A1 (en) | 2013-10-10 | 2015-04-16 | E I Du Pont De Nemours And Company | Fuel compositions containing lignocellulosic biomass fermentation process syrup |
US9725363B2 (en) | 2013-10-10 | 2017-08-08 | E I Du Pont De Nemours And Company | Lignocellulosic biomass fermentation process co-product fuel for cement kiln |
WO2015077752A1 (en) | 2013-11-25 | 2015-05-28 | Genomatica, Inc. | Methods for enhancing microbial production of specific length fatty alcohols in the presence of methanol |
WO2016007365A1 (en) | 2014-07-11 | 2016-01-14 | Genomatica, Inc. | Microorganisms and methods for the production of butadiene using acetyl-coa |
GB201417362D0 (en) * | 2014-10-01 | 2014-11-12 | Hartley Brian S | Devices and methods for selection of microbial strains |
JP7030980B2 (ja) | 2018-07-05 | 2022-03-07 | 富士フイルム株式会社 | 細胞培養装置及び撹拌方法 |
JP7481608B2 (ja) * | 2019-06-20 | 2024-05-13 | シンフォニアテクノロジー株式会社 | 細胞培養装置 |
FR3110596A1 (fr) | 2020-05-21 | 2021-11-26 | Altar | Procédé de culture cellulaire en continu de cellules vivantes pour l’évolution adaptative desdites cellules vivantes. |
US20220056394A1 (en) * | 2020-08-18 | 2022-02-24 | Upside Foods, Inc. | Systems, devices, and methods for sterilizing bioreactors and culture media |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2147271A (en) * | 1937-07-16 | 1939-02-14 | Schwarz Lab Inc | Pure yeast culture apparatus |
FR1064614A (fr) * | 1949-06-21 | 1954-05-17 | Procédé et dispositif pour la production de gaz méthane, dane les installations septiques rurales en particulier | |
JPS59173086A (ja) | 1983-03-24 | 1984-09-29 | Res Assoc Petroleum Alternat Dev<Rapad> | 固定化酵母を用いたアルコ−ル発酵方法 |
US5316905A (en) * | 1986-09-29 | 1994-05-31 | Suzuki Shokan Co., Ltd. | Culture medium supplying method and culture system |
US6022742A (en) * | 1986-11-26 | 2000-02-08 | Kopf; Henry B. | Culture device and method |
JP2677602B2 (ja) * | 1987-05-23 | 1997-11-17 | 武田薬品工業株式会社 | 継代シード培養によるl−ソルボースの製造法およびそれに用いる装置 |
US5242593A (en) * | 1988-12-09 | 1993-09-07 | Oberkofler Joerg | Method for reducing the build-up of slime and/or film in water circulation systems |
JP2983384B2 (ja) * | 1992-07-15 | 1999-11-29 | 株式会社日立製作所 | 生物細胞の継代懸濁培養方法及び培養装置 |
FR2702764B1 (fr) * | 1993-03-19 | 1995-04-28 | Gaz De France | Procédé et installation de fermentation anaérobie de matières organiques. |
DE4331409C1 (de) * | 1993-09-15 | 1994-11-10 | Bam Apparate Und Maschinenbau | Verfahren und Anlage zur Vermehrung von Bierhefe |
EP0748373B1 (de) * | 1994-03-02 | 2000-12-27 | Bitop Gesellschaft für biotechnische Optimierung MbH | Verfahren für die züchtung von mikroorganismen |
JPH0838157A (ja) * | 1994-08-03 | 1996-02-13 | Chikyu Kankyo Sangyo Gijutsu Kenkyu Kiko | 培養液移送装置 |
DE19501350C1 (de) * | 1995-01-18 | 1996-04-04 | Henkel Kgaa | Verfahren zur Herabsetzung der Ablagerung von Schleimstoffen in Kreislaufwässern |
FR2803853B1 (fr) * | 2000-01-17 | 2004-10-22 | Farzin Sarem | Dispositif de culture cellulaire et tissulaire a circulation perfectionnee de fluide de culture |
-
1998
- 1998-12-04 DE DE19856136A patent/DE19856136C2/de not_active Expired - Fee Related
-
1999
- 1999-12-02 PT PT99961053T patent/PT1135460E/pt unknown
- 1999-12-02 WO PCT/EP1999/009422 patent/WO2000034433A1/de active IP Right Grant
- 1999-12-02 JP JP2000586867A patent/JP4615722B2/ja not_active Expired - Lifetime
- 1999-12-02 IL IL14330099A patent/IL143300A0/xx active IP Right Grant
- 1999-12-02 EP EP99961053A patent/EP1135460B1/de not_active Expired - Lifetime
- 1999-12-02 AU AU17799/00A patent/AU779542B2/en not_active Expired
- 1999-12-02 MX MXPA01005523A patent/MXPA01005523A/es active IP Right Grant
- 1999-12-02 DE DE59905586T patent/DE59905586D1/de not_active Expired - Lifetime
- 1999-12-02 DK DK99961053T patent/DK1135460T3/da active
- 1999-12-02 ES ES99961053T patent/ES2193769T3/es not_active Expired - Lifetime
- 1999-12-02 NZ NZ511961A patent/NZ511961A/en not_active IP Right Cessation
- 1999-12-02 AT AT99961053T patent/ATE240388T1/de active
- 1999-12-02 US US09/857,226 patent/US6686194B1/en not_active Expired - Lifetime
- 1999-12-02 CA CA002358437A patent/CA2358437C/en not_active Expired - Lifetime
-
2001
- 2001-05-22 IL IL143300A patent/IL143300A/en not_active IP Right Cessation
-
2002
- 2002-02-22 HK HK02101360.8A patent/HK1039790B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU779542B2 (en) | 2005-01-27 |
IL143300A (en) | 2006-12-31 |
ATE240388T1 (de) | 2003-05-15 |
EP1135460B1 (de) | 2003-05-14 |
HK1039790B (zh) | 2004-01-21 |
AU1779900A (en) | 2000-06-26 |
US6686194B1 (en) | 2004-02-03 |
JP2002531114A (ja) | 2002-09-24 |
CA2358437A1 (en) | 2000-06-15 |
DE19856136C2 (de) | 2002-10-24 |
HK1039790A1 (en) | 2002-05-10 |
MXPA01005523A (es) | 2003-07-14 |
JP4615722B2 (ja) | 2011-01-19 |
EP1135460A1 (de) | 2001-09-26 |
WO2000034433A1 (de) | 2000-06-15 |
DK1135460T3 (da) | 2003-08-11 |
DE19856136A1 (de) | 2000-06-08 |
DE59905586D1 (de) | 2003-06-18 |
NZ511961A (en) | 2003-08-29 |
IL143300A0 (en) | 2002-04-21 |
ES2193769T3 (es) | 2003-11-01 |
CA2358437C (en) | 2009-03-10 |
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