PT1109795E - Derivados de acido de tiazolina - Google Patents

Derivados de acido de tiazolina

Info

Publication number
PT1109795E
PT1109795E PT99945267T PT99945267T PT1109795E PT 1109795 E PT1109795 E PT 1109795E PT 99945267 T PT99945267 T PT 99945267T PT 99945267 T PT99945267 T PT 99945267T PT 1109795 E PT1109795 E PT 1109795E
Authority
PT
Portugal
Prior art keywords
acid derivatives
tiazoline
diagnosing
pyridyl
humans
Prior art date
Application number
PT99945267T
Other languages
English (en)
Inventor
Raymond J Bergeron Jr
Original Assignee
Univ Florida
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Florida filed Critical Univ Florida
Publication of PT1109795E publication Critical patent/PT1109795E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/04—Chelating agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Game Rules And Presentations Of Slot Machines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pyrrole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
PT99945267T 1998-08-31 1999-08-31 Derivados de acido de tiazolina PT1109795E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/144,103 US6083966A (en) 1998-08-31 1998-08-31 Thiazoline acid derivatives

Publications (1)

Publication Number Publication Date
PT1109795E true PT1109795E (pt) 2006-06-30

Family

ID=22507049

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99945267T PT1109795E (pt) 1998-08-31 1999-08-31 Derivados de acido de tiazolina

Country Status (24)

Country Link
US (9) US6083966A (pt)
EP (1) EP1109795B1 (pt)
JP (3) JP4817498B2 (pt)
KR (1) KR20010074907A (pt)
CN (1) CN100455574C (pt)
AT (1) ATE317392T1 (pt)
AU (1) AU759851B2 (pt)
BR (1) BR9913441B1 (pt)
CA (1) CA2342210C (pt)
CZ (1) CZ2001711A3 (pt)
DE (1) DE69929807T2 (pt)
EA (1) EA200100261A1 (pt)
ES (1) ES2260933T3 (pt)
HK (1) HK1035720A1 (pt)
HU (1) HUP0103165A3 (pt)
IL (2) IL141611A0 (pt)
NO (1) NO321028B1 (pt)
NZ (1) NZ509899A (pt)
PL (1) PL346852A1 (pt)
PT (1) PT1109795E (pt)
TR (1) TR200100541T2 (pt)
UA (1) UA57161C2 (pt)
WO (1) WO2000012493A1 (pt)
YU (1) YU21801A (pt)

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US6083966A (en) * 1998-08-31 2000-07-04 University Of Florida Thiazoline acid derivatives
CA2344913A1 (en) * 1998-09-21 2000-03-30 University Of Florida Research Foundation, Inc. Antimalarial agents
EP1488791A3 (en) * 1998-09-21 2005-04-06 University Of Florida Research Foundation, Inc. Antimalarial agents
US6806363B1 (en) * 1999-04-16 2004-10-19 Mayo Foundation For Medical Education & Research Cobalamin conjugates useful as antitumor agents
MXPA02003772A (es) 1999-10-15 2005-04-28 Mayo Foundation Conjugados de cobalamina, utiles como agentes para obtencion de imagen y como agentes terapeuticos.
US6689788B1 (en) * 2000-08-25 2004-02-10 University Of Florida Method and composition for treatment of inflammatory bowel disease
WO2002055530A2 (en) * 2000-10-25 2002-07-18 Mayo Foundation Transcobalamin binding conjugates useful for treating abnormal cellular proliferation
US6875883B2 (en) * 2002-05-15 2005-04-05 Genzyme Corporation Synthesis of benzonitriles from substituted benzaldehyde
AU2003263948A1 (en) * 2002-08-22 2004-03-11 University Of Florida Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin
US20040044220A1 (en) * 2002-08-22 2004-03-04 University Of Florida Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin
JPWO2004031163A1 (ja) * 2002-10-01 2006-02-02 株式会社カネカ 光学活性α−置換システインまたはその塩の製造方法並びにその合成中間体及びその製造方法
US20040185028A1 (en) * 2003-03-19 2004-09-23 Zhenze Hu Antimicrobial compositions containing ethanolamine buffer and biguanide disinfectant
WO2005034949A1 (en) * 2003-09-09 2005-04-21 University Of Florida Desferrithiocin derivatives and their use as iron chelators
EP1667727B1 (en) * 2003-09-09 2008-07-09 University of Florida Research Foundation, Inc. Polyamine-metal chelator conjugates
WO2005055931A2 (en) * 2003-12-03 2005-06-23 University Of Medicine And Dentistry Of New Jersey Method of preventing survival of retrovirally cells and of inhibiting formation of infectious retroviruses
WO2005075475A1 (ja) * 2004-02-04 2005-08-18 Shionogi & Co., Ltd. Ｈｉｖインテグラーゼ阻害活性を有するナフチリジン誘導体
AU2006232929B9 (en) 2005-04-04 2009-12-17 University Of Florida Research Foundation, Inc. Desferrithiocin polyether analogues
US7365371B2 (en) 2005-08-04 2008-04-29 Cree, Inc. Packages for semiconductor light emitting devices utilizing dispensed encapsulants
EP2101764A4 (en) * 2006-12-12 2010-02-17 Univ Florida ACTINIDE DECORPORATION AGENTS ANALOGUES OF DESFERRITHIOCIN
WO2008115433A1 (en) * 2007-03-15 2008-09-25 University Of Florida Desferrithiocin polyether analogues
CA2728636A1 (en) * 2008-07-14 2010-01-21 Ferrokin Biosciences, Inc. Salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents
BR112012028321A2 (pt) 2010-05-04 2017-03-21 Shire Llc "compostos análogos de desazadesferrotiocina e desazadesferrotiocina poliéter como agentes de quelação de metal, composição farmacêutica e usos dos ditos compostos"
CN103562379A (zh) * 2011-05-19 2014-02-05 国立大学法人德岛大学 细胞分化诱导剂以及分化诱导方法
ES2761200T3 (es) 2011-12-16 2020-05-19 Univ Florida Usos de análogos de 4'-desferritiocina
JP6353751B2 (ja) * 2013-09-25 2018-07-04 国立大学法人電気通信大学 新規複素環式化合物及びその塩、並びに、発光基質組成物
AU2014352780A1 (en) * 2013-11-22 2016-06-09 University Of Florida Research Foundation, Inc. Desferrithiocin analogs and uses thereof
EP3288557A4 (en) 2015-04-27 2018-11-07 University of Florida Research Foundation, Inc. Metabolically programmed metal chelators and uses thereof

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US20040044220A1 (en) * 2002-08-22 2004-03-04 University Of Florida Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin
EP1667727B1 (en) 2003-09-09 2008-07-09 University of Florida Research Foundation, Inc. Polyamine-metal chelator conjugates
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WO2008115433A1 (en) * 2007-03-15 2008-09-25 University Of Florida Desferrithiocin polyether analogues

Also Published As

Publication number Publication date
JP2002523500A (ja) 2002-07-30
JP4817498B2 (ja) 2011-11-16
NZ509899A (en) 2003-12-19
US6521652B1 (en) 2003-02-18
HUP0103165A2 (hu) 2002-01-28
BR9913441B1 (pt) 2013-10-29
JP2011178797A (ja) 2011-09-15
CN1313856A (zh) 2001-09-19
NO20011003D0 (no) 2001-02-27
CA2342210C (en) 2009-03-10
DE69929807D1 (de) 2006-04-20
US20070238767A1 (en) 2007-10-11
WO2000012493A9 (en) 2002-04-11
IL141611A (en) 2006-12-31
US6525080B1 (en) 2003-02-25
AU5789799A (en) 2000-03-21
EP1109795B1 (en) 2006-02-08
WO2000012493A1 (en) 2000-03-09
ES2260933T3 (es) 2006-11-01
PL346852A1 (en) 2002-03-11
EP1109795A1 (en) 2001-06-27
EA200100261A1 (ru) 2001-10-22
YU21801A (sh) 2005-07-19
US7531563B2 (en) 2009-05-12
AU759851B2 (en) 2003-05-01
USRE39132E1 (en) 2006-06-13
US20100094016A1 (en) 2010-04-15
NO20011003L (no) 2001-02-27
NO321028B1 (no) 2006-02-27
HUP0103165A3 (en) 2003-03-28
ATE317392T1 (de) 2006-02-15
CZ2001711A3 (cs) 2001-09-12
CA2342210A1 (en) 2000-03-09
KR20010074907A (ko) 2001-08-09
US20050033057A1 (en) 2005-02-10
JP5520875B2 (ja) 2014-06-11
US6559315B1 (en) 2003-05-06
US8008502B2 (en) 2011-08-30
CN100455574C (zh) 2009-01-28
DE69929807T2 (de) 2006-11-02
UA57161C2 (uk) 2003-06-16
EP1109795A4 (en) 2002-01-16
JP2014065730A (ja) 2014-04-17
HK1035720A1 (en) 2003-04-24
US7126004B2 (en) 2006-10-24
BR9913441A (pt) 2001-10-23
IL141611A0 (en) 2002-03-10
US20030236417A1 (en) 2003-12-25
US6083966A (en) 2000-07-04
TR200100541T2 (tr) 2001-11-21

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