PT1086077E - Novos antiestrogeneos processo para a sua preparacao e sua utilizacao farmaceutica - Google Patents
Novos antiestrogeneos processo para a sua preparacao e sua utilizacao farmaceuticaInfo
- Publication number
- PT1086077E PT1086077E PT99931059T PT99931059T PT1086077E PT 1086077 E PT1086077 E PT 1086077E PT 99931059 T PT99931059 T PT 99931059T PT 99931059 T PT99931059 T PT 99931059T PT 1086077 E PT1086077 E PT 1086077E
- Authority
- PT
- Portugal
- Prior art keywords
- preparing
- pharmaceutical composition
- novel process
- novel
- pharmaceutical
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/32—Antioestrogens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/16—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C317/18—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C323/11—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/12—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/14—All rings being cycloaliphatic
- C07C2602/24—All rings being cycloaliphatic the ring system containing nine carbon atoms, e.g. perhydroindane
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19826213A DE19826213A1 (de) | 1998-06-09 | 1998-06-09 | Neue Antiestrogene, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1086077E true PT1086077E (pt) | 2004-08-31 |
Family
ID=7870694
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT99931059T PT1086077E (pt) | 1998-06-09 | 1999-06-09 | Novos antiestrogeneos processo para a sua preparacao e sua utilizacao farmaceutica |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US6166075A (pt) |
| EP (1) | EP1086077B1 (pt) |
| JP (1) | JP2002517482A (pt) |
| KR (1) | KR20010052688A (pt) |
| CN (1) | CN1305457A (pt) |
| AR (1) | AR023629A1 (pt) |
| AT (1) | ATE263755T1 (pt) |
| AU (1) | AU759942B2 (pt) |
| BR (1) | BR9911103A (pt) |
| CA (1) | CA2334780A1 (pt) |
| CO (1) | CO5050355A1 (pt) |
| DE (2) | DE19826213A1 (pt) |
| DK (1) | DK1086077T3 (pt) |
| ES (1) | ES2220072T3 (pt) |
| HU (1) | HUP0102211A3 (pt) |
| IL (1) | IL139863A0 (pt) |
| PE (1) | PE20000541A1 (pt) |
| PL (1) | PL344309A1 (pt) |
| PT (1) | PT1086077E (pt) |
| WO (1) | WO1999064393A1 (pt) |
| ZA (1) | ZA200100201B (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19826213A1 (de) * | 1998-06-09 | 1999-12-16 | Schering Ag | Neue Antiestrogene, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung |
| US6525069B1 (en) * | 1998-12-18 | 2003-02-25 | Bristol-Myers Squibb Pharma Co. | N-ureidoalkyl-piperidines as modulators of chemokine receptor activity |
| DE10039199A1 (de) * | 2000-08-10 | 2002-02-21 | Schering Ag | Kombinationspräparate aus einem ERß selektiven Estrogen und einem SERM oder Antiestrogen |
| EP1365763B1 (en) * | 2001-02-15 | 2008-11-26 | Janssen Pharmaceutica N.V. | Farnesyl protein transferase inhibitor combinations with antiestrogen agents |
| DE10142881A1 (de) * | 2001-09-03 | 2003-04-03 | Jomed Gmbh | Implantate mit Combretastatin A-4 (CA4) |
| WO2005000775A2 (en) * | 2003-05-31 | 2005-01-06 | Janssen Pharmaceutica, N.V. | Cyclohexyl derivatives as selective estrogen receptor modulators |
| US7750631B2 (en) * | 2007-06-22 | 2010-07-06 | Morpho Detection, Inc. | Passenger inspection system and methods for using the same |
| CA2653189A1 (en) | 2008-02-04 | 2009-08-04 | University Of Ottawa | Estrogenic compounds, process for their production and pharmaceutical uses thereof |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4133814A (en) * | 1975-10-28 | 1979-01-09 | Eli Lilly And Company | 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents |
| FR2685332A1 (fr) * | 1991-12-20 | 1993-06-25 | Roussel Uclaf | Nouveaux 19-nor sterouides ayant en position 11beta une chaine thiocarbonee, leur procede de preparation et les intermediaires et leur application a titre de medicaments. |
| US5482949A (en) * | 1993-03-19 | 1996-01-09 | Eli Lilly And Company | Sulfonate derivatives of 3-aroylbenzo[b]thiophenes |
| FR2744445B1 (fr) * | 1996-02-01 | 1998-10-02 | Roussel Uclaf | Composes biphenyles nouveaux et/ou a titre de medicament, compositions pharmaceutiques les contenant, leur procede de preparation et les intermediaires de ce procede |
| DE19826213A1 (de) * | 1998-06-09 | 1999-12-16 | Schering Ag | Neue Antiestrogene, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung |
-
1998
- 1998-06-09 DE DE19826213A patent/DE19826213A1/de not_active Withdrawn
-
1999
- 1999-06-07 PE PE1999000482A patent/PE20000541A1/es not_active Application Discontinuation
- 1999-06-08 CO CO99035556A patent/CO5050355A1/es unknown
- 1999-06-09 HU HU0102211A patent/HUP0102211A3/hu unknown
- 1999-06-09 JP JP2000553403A patent/JP2002517482A/ja active Pending
- 1999-06-09 US US09/328,451 patent/US6166075A/en not_active Expired - Fee Related
- 1999-06-09 ES ES99931059T patent/ES2220072T3/es not_active Expired - Lifetime
- 1999-06-09 IL IL13986399A patent/IL139863A0/xx unknown
- 1999-06-09 CN CN99807191A patent/CN1305457A/zh active Pending
- 1999-06-09 WO PCT/EP1999/004049 patent/WO1999064393A1/de not_active Application Discontinuation
- 1999-06-09 DK DK99931059T patent/DK1086077T3/da active
- 1999-06-09 CA CA002334780A patent/CA2334780A1/en not_active Abandoned
- 1999-06-09 AR ARP990102729A patent/AR023629A1/es not_active Application Discontinuation
- 1999-06-09 AT AT99931059T patent/ATE263755T1/de not_active IP Right Cessation
- 1999-06-09 EP EP99931059A patent/EP1086077B1/de not_active Expired - Lifetime
- 1999-06-09 PT PT99931059T patent/PT1086077E/pt unknown
- 1999-06-09 AU AU47716/99A patent/AU759942B2/en not_active Ceased
- 1999-06-09 PL PL99344309A patent/PL344309A1/xx not_active Application Discontinuation
- 1999-06-09 DE DE59909123T patent/DE59909123D1/de not_active Expired - Fee Related
- 1999-06-09 KR KR1020007013943A patent/KR20010052688A/ko not_active Application Discontinuation
- 1999-06-09 BR BR9911103-9A patent/BR9911103A/pt not_active IP Right Cessation
-
2000
- 2000-11-07 US US09/706,806 patent/US6559181B1/en not_active Expired - Fee Related
-
2001
- 2001-01-08 ZA ZA200100201A patent/ZA200100201B/en unknown
-
2003
- 2003-02-21 US US10/369,577 patent/US7074829B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20030162830A1 (en) | 2003-08-28 |
| DE19826213A1 (de) | 1999-12-16 |
| ATE263755T1 (de) | 2004-04-15 |
| US6166075A (en) | 2000-12-26 |
| WO1999064393A1 (de) | 1999-12-16 |
| BR9911103A (pt) | 2001-03-06 |
| EP1086077B1 (de) | 2004-04-07 |
| AU759942B2 (en) | 2003-05-01 |
| CO5050355A1 (es) | 2001-06-27 |
| PE20000541A1 (es) | 2000-08-10 |
| JP2002517482A (ja) | 2002-06-18 |
| EP1086077A1 (de) | 2001-03-28 |
| US6559181B1 (en) | 2003-05-06 |
| IL139863A0 (en) | 2002-02-10 |
| DK1086077T3 (da) | 2004-08-02 |
| CN1305457A (zh) | 2001-07-25 |
| ZA200100201B (en) | 2002-01-08 |
| US7074829B2 (en) | 2006-07-11 |
| PL344309A1 (en) | 2001-10-22 |
| CA2334780A1 (en) | 1999-12-16 |
| HUP0102211A3 (en) | 2002-12-28 |
| KR20010052688A (ko) | 2001-06-25 |
| HUP0102211A2 (hu) | 2002-03-28 |
| AU4771699A (en) | 1999-12-30 |
| AR023629A1 (es) | 2002-09-04 |
| ES2220072T3 (es) | 2004-12-01 |
| DE59909123D1 (de) | 2004-05-13 |
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