PT1079849E - Utilizacao de proteinas hmg para a preparacao de medicamentos com actividade citotoxica - Google Patents
Utilizacao de proteinas hmg para a preparacao de medicamentos com actividade citotoxicaInfo
- Publication number
- PT1079849E PT1079849E PT99926330T PT99926330T PT1079849E PT 1079849 E PT1079849 E PT 1079849E PT 99926330 T PT99926330 T PT 99926330T PT 99926330 T PT99926330 T PT 99926330T PT 1079849 E PT1079849 E PT 1079849E
- Authority
- PT
- Portugal
- Prior art keywords
- medicines
- preparation
- cytotoxic activity
- hmg proteins
- hmg
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT98MI001094A IT1299583B1 (it) | 1998-05-19 | 1998-05-19 | Uso di proteine hmg-i per la preparazione di medicamenti ad attivita' citotossica |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1079849E true PT1079849E (pt) | 2002-06-28 |
Family
ID=11380053
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT99926330T PT1079849E (pt) | 1998-05-19 | 1999-05-19 | Utilizacao de proteinas hmg para a preparacao de medicamentos com actividade citotoxica |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1079849B1 (pt) |
JP (1) | JP2002515445A (pt) |
AT (1) | ATE211391T1 (pt) |
AU (1) | AU4363199A (pt) |
DE (1) | DE69900756T2 (pt) |
DK (1) | DK1079849T3 (pt) |
ES (1) | ES2171086T3 (pt) |
IT (1) | IT1299583B1 (pt) |
PT (1) | PT1079849E (pt) |
WO (1) | WO1999059609A2 (pt) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7151082B2 (en) | 1999-02-11 | 2006-12-19 | The Feinstein Institute For Medical Research | Antagonists of HMG1 for treating inflammatory conditions |
US6303321B1 (en) | 1999-02-11 | 2001-10-16 | North Shore-Long Island Jewish Research Institute | Methods for diagnosing sepsis |
US20020164644A1 (en) * | 2000-04-05 | 2002-11-07 | Ikuro Maruyama | Adsorbents for high mobility group proteins and column for purifying body fluid |
US7220723B2 (en) | 2001-05-15 | 2007-05-22 | The Feinstein Institute For Medical Research | Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents |
US7304034B2 (en) | 2001-05-15 | 2007-12-04 | The Feinstein Institute For Medical Research | Use of HMGB fragments as anti-inflammatory agents |
ITMI20011986A1 (it) * | 2001-09-25 | 2003-03-25 | San Raffaele Centro Fond | Metodo e composizione per l'attivazione di cellule presentanti l'antigene |
JP2005511770A (ja) * | 2001-12-19 | 2005-04-28 | アルケド バイオテック ゲーエムベーハー | Hmgbタンパク質およびhmgbタンパク質をコードする核酸の使用方法 |
GB0226251D0 (en) * | 2002-11-11 | 2002-12-18 | San Raffaele Centro Fond | Acetylated protein |
US7696169B2 (en) | 2003-06-06 | 2010-04-13 | The Feinstein Institute For Medical Research | Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents |
EP1668035A2 (en) | 2003-09-11 | 2006-06-14 | Critical Therapeutics, Inc. | Monoclonal antibodies against hmgb1 |
US8129130B2 (en) | 2004-10-22 | 2012-03-06 | The Feinstein Institute For Medical Research | High affinity antibodies against HMGB1 and methods of use thereof |
AU2005333602B2 (en) | 2004-10-22 | 2012-04-12 | Medimmune, Llc | High affinity antibodies against HMGB1 and methods of use thereof |
CA2631212A1 (en) | 2005-11-28 | 2007-07-05 | Medimmune, Llc | Antagonists of hmgb1 and/or rage and methods of use thereof |
DK2525817T3 (en) | 2010-01-21 | 2017-10-02 | Univ Arkansas | Vaccine vectors and methods for enhancing immune responses |
NZ702839A (en) | 2010-06-09 | 2016-04-29 | Univ Arkansas | Vaccine and methods to reduce campylobacter infection |
PT2956165T (pt) | 2013-02-14 | 2019-11-29 | Texas A & M Univ Sys | Composições e métodos de potenciação das respostas imunitárias frente a eimeria ou limitação de uma infeção por eimeria |
AU2014239557B2 (en) | 2013-03-15 | 2019-01-03 | The Board Of Trustees Of The University Of Arkansas | Compositions and methods of enhancing immune responses to enteric pathogens |
JP7467027B2 (ja) | 2016-05-03 | 2024-04-15 | ザ ボード オブ トラスティーズ オブ ザ ユニバーシティ オブ アーカンソー | 免疫刺激性ポリペプチドおよび抗原性ポリペプチドを含む酵母ワクチンベクター並びにそれを使用する方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS62166897A (ja) * | 1986-01-20 | 1987-07-23 | Toyo Soda Mfg Co Ltd | 核内非ヒストン蛋白質に対するモノクロ−ナル抗体 |
EP0727487A1 (en) * | 1995-02-17 | 1996-08-21 | K.U. Leuven Research & Development | Multiple-tumor aberrant growth genes |
FR2739292B1 (fr) * | 1995-09-28 | 1997-10-31 | Rhone Poulenc Rorer Sa | Composition pharmaceutique utile pour la transfection d'acides nucleiques et ses utilisations |
JP3018313B2 (ja) * | 1996-02-23 | 2000-03-13 | 雪印乳業株式会社 | 骨形成促進及び骨吸収防止剤 |
-
1998
- 1998-05-19 IT IT98MI001094A patent/IT1299583B1/it active IP Right Grant
-
1999
- 1999-05-19 PT PT99926330T patent/PT1079849E/pt unknown
- 1999-05-19 JP JP2000549273A patent/JP2002515445A/ja active Pending
- 1999-05-19 DE DE69900756T patent/DE69900756T2/de not_active Expired - Fee Related
- 1999-05-19 ES ES99926330T patent/ES2171086T3/es not_active Expired - Lifetime
- 1999-05-19 WO PCT/EP1999/003431 patent/WO1999059609A2/en active IP Right Grant
- 1999-05-19 DK DK99926330T patent/DK1079849T3/da active
- 1999-05-19 EP EP99926330A patent/EP1079849B1/en not_active Expired - Lifetime
- 1999-05-19 AT AT99926330T patent/ATE211391T1/de not_active IP Right Cessation
- 1999-05-19 AU AU43631/99A patent/AU4363199A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO1999059609A2 (en) | 1999-11-25 |
WO1999059609A3 (en) | 2000-01-27 |
AU4363199A (en) | 1999-12-06 |
DE69900756T2 (de) | 2003-03-13 |
ATE211391T1 (de) | 2002-01-15 |
ES2171086T3 (es) | 2002-08-16 |
EP1079849A2 (en) | 2001-03-07 |
EP1079849B1 (en) | 2002-01-02 |
DE69900756D1 (de) | 2002-02-28 |
DK1079849T3 (da) | 2002-04-22 |
IT1299583B1 (it) | 2000-03-16 |
JP2002515445A (ja) | 2002-05-28 |
ITMI981094A1 (it) | 1999-11-19 |
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