PT1061955E - Composicao de polinucleotido, metodo de preparacao e sua utilizacao - Google Patents

Composicao de polinucleotido, metodo de preparacao e sua utilizacao

Info

Publication number
PT1061955E
PT1061955E PT99912502T PT99912502T PT1061955E PT 1061955 E PT1061955 E PT 1061955E PT 99912502 T PT99912502 T PT 99912502T PT 99912502 T PT99912502 T PT 99912502T PT 1061955 E PT1061955 E PT 1061955E
Authority
PT
Portugal
Prior art keywords
polynucleotide
composition
polynucleotide composition
lyophilized
cryoprotectant
Prior art date
Application number
PT99912502T
Other languages
English (en)
Inventor
Patrick P Deluca
Musunuri Shankar
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of PT1061955E publication Critical patent/PT1061955E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT99912502T 1998-03-13 1999-03-12 Composicao de polinucleotido, metodo de preparacao e sua utilizacao PT1061955E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7808098P 1998-03-13 1998-03-13

Publications (1)

Publication Number Publication Date
PT1061955E true PT1061955E (pt) 2005-08-31

Family

ID=22141799

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99912502T PT1061955E (pt) 1998-03-13 1999-03-12 Composicao de polinucleotido, metodo de preparacao e sua utilizacao

Country Status (14)

Country Link
US (1) US20080081366A1 (pt)
EP (1) EP1061955B1 (pt)
JP (1) JP2002506048A (pt)
KR (1) KR100625385B1 (pt)
CN (1) CN100471522C (pt)
AT (1) ATE294594T1 (pt)
AU (1) AU765177B2 (pt)
BR (1) BR9908754A (pt)
CA (1) CA2322232A1 (pt)
DE (1) DE69925113T2 (pt)
ES (1) ES2239440T3 (pt)
IL (1) IL138306A0 (pt)
PT (1) PT1061955E (pt)
WO (1) WO1999045966A1 (pt)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1173744C (zh) * 1998-05-22 2004-11-03 住友制药株式会社 稳定的基因制剂
AU5345999A (en) * 1998-08-14 2000-03-06 Valentis, Inc. Protected one-vial formulation for nucleic acid molecules, methods of making thesame by in-line mixing, and related products and methods
AU783918B2 (en) * 1999-11-19 2005-12-22 Eisai Inc. Continuous-flow method for preparing microparticles
JP2001316297A (ja) * 2000-02-23 2001-11-13 Kaken Pharmaceut Co Ltd 遺伝子包埋リポソーム製剤及びその製法
DK1456377T3 (da) * 2001-12-20 2019-09-23 Merck Sharp & Dohme Syn3-sammensætninger og fremgangsmåder
AU2003218168A1 (en) * 2002-03-15 2003-09-29 University Of Southern California Ophthalmic solutions for delivery of expression vectors
US7615229B2 (en) 2002-03-15 2009-11-10 Wyeth Holdings Corporation Mutants of the P4 protein of nontypable Haemophilus influenzae with reduced enzymatic activity
EP1581201A4 (en) 2002-12-23 2011-03-30 Vical Inc METHOD FOR PRODUCING STERILIC DRUGS ON POLYNUCLEOTIDE BASIS
US7521187B2 (en) * 2002-12-23 2009-04-21 Vical Incorporated Method for freeze-drying nucleic acid/block copolymer/cationic surfactant complexes
TW200613554A (en) 2004-06-17 2006-05-01 Wyeth Corp Plasmid having three complete transcriptional units and immunogenic compositions for inducing an immune response to HIV
CA2631714C (en) 2005-12-02 2014-09-16 Novartis Ag Nanoparticles for use in immunogenic compositions
KR100777249B1 (ko) 2006-02-14 2007-11-28 (주)바이오니아 건조 올리고뉴클레오티드 조성물 및 이의 제조 방법
DE102006038240A1 (de) * 2006-08-07 2008-02-14 Biotronik Vi Patent Ag Verfahren zur Herstellung eines Komposits aus Oligo- oder Polynucleotiden und hydrophoben biodegradierbaren Polymeren sowie nach dem Verfahren erhaltenes Komposit
GB0701253D0 (en) 2007-01-23 2007-02-28 Diagnostics For The Real World Nucleic acid amplification and testing
EP1970441A1 (en) * 2007-03-06 2008-09-17 BioAlliance Pharma Plasmid containing a sequence encoding a disintegrin domain of metargidin (RDD)
US20090258932A1 (en) 2008-04-09 2009-10-15 Viromed Co., Ltd. Lyophilized DNA Formulations for Enhanced Expression of Plasmid DNA
WO2012170889A1 (en) 2011-06-08 2012-12-13 Shire Human Genetic Therapies, Inc. Cleavable lipids
CA2879443A1 (en) 2012-07-19 2014-01-23 Zoetis Llc Bovine influenza virus compositions
RU2542385C2 (ru) 2012-08-31 2015-02-20 Общество с ограниченной ответственностью "НекстГен" Способ получения фармацевтической композиции для индукции развития кровеносных сосудов в тканях, фармацевтическая композиция, полученная этим способом, и способ лечения ишемии тканей и/или органов человека
CN105682676B (zh) 2013-10-22 2020-10-23 赫利世弥斯株式会社 利用肝细胞生长因子的两种以上的异构体的肌萎缩性侧索硬化症预防或治疗用组合物
AU2015373071B2 (en) * 2014-12-29 2022-03-31 Toray Industries, Inc. Composition containing nucleic acid molecule stably
RU2612497C2 (ru) 2015-05-26 2017-03-09 Общество с ограниченной ответственностью "НекстГен" Оптимизированная нуклеотидная последовательность и фармацевтическая композиция на ее основе с пролонгированной экспрессией трансгена vegf
CN115141772A (zh) 2015-08-14 2022-10-04 硕腾服务有限责任公司 牛支原体组合物
PL3534922T3 (pl) 2016-11-04 2024-08-19 Takeda Pharmaceutical Company Limited Preparaty wirusa związanego z adenowirusem
CN112088017B (zh) * 2018-07-19 2023-11-21 赫利世弥斯株式会社 用于裸脱氧核糖核酸基因疗法的经冷冻干燥的药剂学组合物
CN110596227B (zh) * 2019-08-08 2021-11-23 河北省食品检验研究院（国家果类及农副加工产品质量监督检验中心、河北省食品安全实验室） 飞行时间质谱即用型斯坦利沙门氏菌定性标准样品的制备方法
KR102460006B1 (ko) * 2021-11-22 2022-10-27 주식회사 리엔젠 폴리뉴클레오타이드 및 히알루론산 포함하는 피부 필러 조성물의 동결건조 제조방법 및 이에 따라 제조된 폴리뉴클레오타이드 및 히알루론산 포함하는 피부 필러 조성물

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2309692A (en) * 1991-07-03 1993-02-11 Cryolife, Inc. Method for stabilization of biomaterials
US5709076A (en) * 1992-09-14 1998-01-20 Lawlor; Shawn P. Method and apparatus for power generation using rotating ramjet which compresses inlet air and expands exhaust gas against stationary peripheral wall
JPH08511956A (ja) * 1994-04-07 1996-12-17 アクゾ・ノベル・エヌ・ベー Ｒｎａを含む凍結乾燥組成物
WO1996027393A1 (en) * 1995-03-07 1996-09-12 University Of Pittsburgh A dry powder formulation for gene therapy
US5811406A (en) * 1995-06-07 1998-09-22 Regents Of The University Of California Dry powder formulations of polynucleotide complexes
ZA973642B (en) * 1996-04-26 1997-11-25 Merck & Co Inc DNA vaccine formulations.
AU727306B2 (en) * 1996-04-26 2000-12-07 Merck Sharp & Dohme Corp. DNA vaccine formulations
DE19716154A1 (de) * 1997-04-18 1998-10-22 Boehringer Mannheim Gmbh Stabile pharmazeutische Darreichungsform für Peptide, Proteine und Nukleinsäuren

Also Published As

Publication number Publication date
ES2239440T3 (es) 2005-09-16
AU3086899A (en) 1999-09-27
CN100471522C (zh) 2009-03-25
ATE294594T1 (de) 2005-05-15
CA2322232A1 (en) 1999-09-16
IL138306A0 (en) 2001-10-31
EP1061955B1 (en) 2005-05-04
WO1999045966A1 (en) 1999-09-16
EP1061955A1 (en) 2000-12-27
DE69925113T2 (de) 2006-01-19
CN1294520A (zh) 2001-05-09
BR9908754A (pt) 2000-11-28
KR100625385B1 (ko) 2006-09-18
US20080081366A1 (en) 2008-04-03
KR20010074441A (ko) 2001-08-04
DE69925113D1 (de) 2005-06-09
JP2002506048A (ja) 2002-02-26
AU765177B2 (en) 2003-09-11

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