PT1040106E - Derivados de cromano substituidos com carboxi uteis como agonistas de adrenoreceptor beta 3 - Google Patents

Derivados de cromano substituidos com carboxi uteis como agonistas de adrenoreceptor beta 3

Info

Publication number
PT1040106E
PT1040106E PT98963240T PT98963240T PT1040106E PT 1040106 E PT1040106 E PT 1040106E PT 98963240 T PT98963240 T PT 98963240T PT 98963240 T PT98963240 T PT 98963240T PT 1040106 E PT1040106 E PT 1040106E
Authority
PT
Portugal
Prior art keywords
uteis
carboxy
chroman derivatives
derivatives substituted
adrenoreceptor agonists
Prior art date
Application number
PT98963240T
Other languages
English (en)
Inventor
Richard D Connell
Timothy G Lease
Jeremy Baryza
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of PT1040106E publication Critical patent/PT1040106E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
PT98963240T 1997-12-19 1998-12-16 Derivados de cromano substituidos com carboxi uteis como agonistas de adrenoreceptor beta 3 PT1040106E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US99462097A 1997-12-19 1997-12-19

Publications (1)

Publication Number Publication Date
PT1040106E true PT1040106E (pt) 2002-11-29

Family

ID=25540853

Family Applications (1)

Application Number Title Priority Date Filing Date
PT98963240T PT1040106E (pt) 1997-12-19 1998-12-16 Derivados de cromano substituidos com carboxi uteis como agonistas de adrenoreceptor beta 3

Country Status (24)

Country Link
EP (1) EP1040106B1 (pt)
JP (1) JP2001526282A (pt)
KR (1) KR20010033188A (pt)
CN (1) CN1284952A (pt)
AT (1) ATE222901T1 (pt)
AU (1) AU749097B2 (pt)
BG (1) BG104593A (pt)
BR (1) BR9814302A (pt)
CA (1) CA2316971A1 (pt)
DE (1) DE69807523T2 (pt)
DK (1) DK1040106T3 (pt)
ES (1) ES2183434T3 (pt)
HU (1) HUP0004565A3 (pt)
ID (1) ID26524A (pt)
IL (1) IL136689A0 (pt)
NO (1) NO20003083L (pt)
NZ (1) NZ505200A (pt)
PL (1) PL341229A1 (pt)
PT (1) PT1040106E (pt)
RU (1) RU2223269C2 (pt)
SK (1) SK9362000A3 (pt)
TR (1) TR200001927T2 (pt)
UA (1) UA62993C2 (pt)
WO (1) WO1999032476A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR035605A1 (es) 2000-12-11 2004-06-16 Bayer Corp Derivados de aminometil cromano di-sustituidos, un metodo para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la manufactura de medicamentos utiles como agonistas beta-3-adreno-receptores
AR035858A1 (es) * 2001-04-23 2004-07-21 Bayer Corp Derivados de cromano 2,6-sustituidos,composiciones farmaceuticas,uso de dichos derivados para la manufactura de medicamentos utiles como agonistas adrenorreceptores beta-3
JPWO2003033468A1 (ja) * 2001-10-17 2005-02-03 株式会社カネカ (S)−α−ハロメチルピリジンメタノール誘導体の製造方法
MY147767A (en) * 2004-06-16 2013-01-31 Janssen Pharmaceutica Nv Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders
WO2006089053A2 (en) 2005-02-17 2006-08-24 Wyeth Cycloalkylfused indole, benzothiophene, benzofuran and indene derivatives
EP1803716B1 (en) * 2005-12-28 2012-07-25 Acino Pharma AG A process for preparation of racemic nebivolol
US7560575B2 (en) 2005-12-28 2009-07-14 Acino Pharma Ag Process for preparation of racemic Nebivolol
ES2534336B1 (es) * 2013-10-18 2016-01-28 Artax Biopharma Inc. Derivados de cromeno como inhibidores de la interacción TCR-Nck
ES2534318B1 (es) * 2013-10-18 2016-01-28 Artax Biopharma Inc. Derivados de cromeno sustituidos por alcóxido como inhibidores de la interacción TCR-Nck

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1337429C (en) * 1983-12-05 1995-10-24 Guy Rosalia Eugene Van Lommen Derivatives of 2,2'-iminobisethanol
GB8801306D0 (en) * 1988-01-21 1988-02-17 Ici Plc Chemical compounds
US5451677A (en) * 1993-02-09 1995-09-19 Merck & Co., Inc. Substituted phenyl sulfonamides as selective β 3 agonists for the treatment of diabetes and obesity
NZ265692A (en) * 1993-06-14 1997-02-24 Pfizer Indole- and benzofuran- containing hydroxyamines and analogs; pharmaceutical compositions
GB9405019D0 (en) * 1994-03-15 1994-04-27 Smithkline Beecham Plc Novel compounds
US5561142A (en) * 1994-04-26 1996-10-01 Merck & Co., Inc. Substituted sulfonamides as selective β3 agonists for the treatment of diabetes and obesity
EP0801060A1 (en) * 1996-04-09 1997-10-15 Pfizer Inc. Heterocyclic Beta-3 Adrenergenic Agonists

Also Published As

Publication number Publication date
HUP0004565A2 (hu) 2001-08-28
ES2183434T3 (es) 2003-03-16
DE69807523D1 (de) 2002-10-02
RU2223269C2 (ru) 2004-02-10
HUP0004565A3 (en) 2002-12-28
NO20003083D0 (no) 2000-06-15
BR9814302A (pt) 2000-10-10
JP2001526282A (ja) 2001-12-18
EP1040106A1 (en) 2000-10-04
KR20010033188A (ko) 2001-04-25
DK1040106T3 (da) 2002-12-02
TR200001927T2 (tr) 2001-06-21
NO20003083L (no) 2000-08-15
PL341229A1 (en) 2001-03-26
WO1999032476A1 (en) 1999-07-01
AU749097B2 (en) 2002-06-20
EP1040106B1 (en) 2002-08-28
AU1830099A (en) 1999-07-12
ID26524A (id) 2001-01-11
CN1284952A (zh) 2001-02-21
ATE222901T1 (de) 2002-09-15
DE69807523T2 (de) 2003-01-09
CA2316971A1 (en) 1999-07-01
IL136689A0 (en) 2001-06-14
BG104593A (en) 2001-09-28
SK9362000A3 (en) 2001-09-11
UA62993C2 (en) 2004-01-15
NZ505200A (en) 2002-09-27

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