PT100979A - Epitopos de celula t dos alergenos principais de dermatophagoides (acaro do po domestico), peptidos modificados, sequencias de acidos nucleicos que os codificam, composicoes farmaceuticas que os contem e seu uso - Google Patents

Epitopos de celula t dos alergenos principais de dermatophagoides (acaro do po domestico), peptidos modificados, sequencias de acidos nucleicos que os codificam, composicoes farmaceuticas que os contem e seu uso

Info

Publication number
PT100979A
PT100979A PT100979A PT10097992A PT100979A PT 100979 A PT100979 A PT 100979A PT 100979 A PT100979 A PT 100979A PT 10097992 A PT10097992 A PT 10097992A PT 100979 A PT100979 A PT 100979A
Authority
PT
Portugal
Prior art keywords
peptides
der
cell
dermatophagoides
epithopes
Prior art date
Application number
PT100979A
Other languages
English (en)
Other versions
PT100979B (pt
Inventor
Bruce L Rogers
Richard D Garman
Julia L Greenstein
Mei-Chang Kuo
Original Assignee
Immulogic Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immulogic Pharma Corp filed Critical Immulogic Pharma Corp
Publication of PT100979A publication Critical patent/PT100979A/pt
Publication of PT100979B publication Critical patent/PT100979B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43531—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from mites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Insects & Arthropods (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Housing For Livestock And Birds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT100979A 1991-10-16 1992-10-16 Epitopos de celula t dos alergenos principais de dermatophagoides (acaro do po domestico), peptidos modificados, sequencias de acidos nucleicos que os codificam, composicoes farmaceuticas que os contem e seu uso PT100979B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77785991A 1991-10-16 1991-10-16
US88139692A 1992-05-08 1992-05-08

Publications (2)

Publication Number Publication Date
PT100979A true PT100979A (pt) 1994-01-31
PT100979B PT100979B (pt) 1999-08-31

Family

ID=27119374

Family Applications (1)

Application Number Title Priority Date Filing Date
PT100979A PT100979B (pt) 1991-10-16 1992-10-16 Epitopos de celula t dos alergenos principais de dermatophagoides (acaro do po domestico), peptidos modificados, sequencias de acidos nucleicos que os codificam, composicoes farmaceuticas que os contem e seu uso

Country Status (15)

Country Link
EP (1) EP0623168B1 (pt)
JP (2) JPH07502890A (pt)
KR (1) KR100260342B1 (pt)
AT (1) ATE444360T1 (pt)
AU (1) AU676668B2 (pt)
DE (1) DE69233772D1 (pt)
ES (1) ES2334179T3 (pt)
FI (1) FI110385B (pt)
HU (1) HU220462B1 (pt)
IL (1) IL103452A (pt)
MX (1) MX9205985A (pt)
NO (1) NO314586B1 (pt)
NZ (1) NZ244772A (pt)
PT (1) PT100979B (pt)
WO (1) WO1993008279A1 (pt)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5433948A (en) * 1990-02-13 1995-07-18 Thomas; Wayne R. Cloning and sequencing of allergens of dermatophagoides (house dust mite)
WO1994024281A1 (en) * 1993-04-14 1994-10-27 Immulogic Pharmaceutical Corporation T cell epitopes of the major allergens from dermatophagoides (house dust mite)
EP0650976A4 (en) * 1992-08-14 1997-10-01 Torii & Co Ltd ALLERGENIC PEPTIDE.
CA2164326A1 (en) * 1993-06-02 1994-12-08 Wayne Robert Thomas Cryptic peptides for use in inducing immunologic tolerance
WO1995002412A1 (fr) * 1993-07-16 1995-01-26 Meiji Milk Products Co., Ltd. Agent antiallergie
US6180771B1 (en) 1993-12-08 2001-01-30 Immulogic Pharmaceutical Corp. Nucleic acids encoding a house dust mite allergen, Der p III, and uses therefor
KR100733887B1 (ko) * 1993-12-08 2007-12-20 헤스카 코포레이션 DerpⅢ단백질알레르겐을암호화하는분리된핵산
WO1995017424A1 (fr) * 1993-12-22 1995-06-29 Asahi Breweries, Ltd. NOUVELLE SUBSTANCE ALLERGENE DerI DE RECOMBINAISON, PRECURSEUR DE LADITE SUBSTANCE ET PROCEDE DE PRODUCTION
JPH07215996A (ja) * 1994-01-31 1995-08-15 Torii Yakuhin Kk ダニアレルゲンのｂ細胞エピトープ
DK0755407T3 (da) * 1994-04-14 2007-08-06 Merck Patent Gmbh Farmaceutisk peptidformuleringer til behandling af stövmideallergi
SE9403526D0 (sv) 1994-10-14 1994-10-14 Astra Ab New Peptides
SE9501067D0 (sv) 1995-03-24 1995-03-24 Astra Ab New peptides
ATE412175T1 (de) 1996-03-21 2008-11-15 Circassia Ltd Verwendung von kryptischen peptiden zur induktion von immunologischer toleranz
AU736977C (en) 1996-11-13 2007-10-18 Meiji Co., Ltd. Peptide-based immunotherapeutic agent
AR020102A1 (es) 1998-07-30 2002-04-10 Ucb Sa Compuesto para la prevencion y/o tratamiento de la alergia; composicion farmaceutica, composicion cosmetica, composicion en forma de bebida, alimento y/oalimento para animales domesticos que lo comprende y uso de dicho compuesto o dicha composicion farmaceutica para la fabricacion de un alimento
GB0006437D0 (en) 2000-03-17 2000-05-10 Leuven Res & Dev Vzw Compounds for the modulation of allergen sensitivity by antigens sharing T cell epitopes with allergens
FR2809413B1 (fr) * 2000-05-29 2004-10-22 Tabacs & Allumettes Ind Production d'allergenes recombinants dans des cellules vegetales
GB0108752D0 (en) * 2001-04-06 2001-05-30 Isis Innovation Peptide epitopes and uses thereof
US9249202B2 (en) 2006-08-11 2016-02-02 Life Sciences Research Partners Vzw Immunogenic peptides and their use in immune disorders
GB0710529D0 (en) 2007-06-01 2007-07-11 Circassia Ltd Vaccine
PL2083856T3 (pl) * 2007-08-15 2011-04-29 Circassia Ltd Peptydy do odczulania na alergeny
EP2623125A1 (en) 2008-02-14 2013-08-07 Life Sciences Research Partners VZW Elimination of immune responses to viral vectors
EP2719396B1 (en) 2008-02-14 2017-06-21 Life Sciences Research Partners VZW Immunotherapy targeting intracellular pathogens
US8999346B2 (en) 2008-02-14 2015-04-07 Life Sciences Research Partners Vzw Immunogenic control of tumours and tumour cells
ES2650236T3 (es) 2008-02-14 2018-01-17 Life Sciences Research Partners Vzw Linfocitos T CD4+ con propiedades citolíticas
JP5705113B2 (ja) * 2008-08-15 2015-04-22 サーカッシア リミテッド Ｉｌ−１０産生の刺激のためのアレルゲン由来のｔ細胞抗原
GB0821806D0 (en) 2008-11-28 2009-01-07 Circassia Ltd Compositions with reduced dimer formation
CA2820617C (en) 2010-11-25 2020-01-07 Imnate Sarl Immunogenic peptides for use in the prevention and/or treatment of infectious diseases, autoimmune diseases, immune responses to allofactors, allergic diseases, tumors, graft rejection and immune responses against viral vectors used for gene therapy or gene vaccination
GB201201511D0 (en) 2012-01-30 2012-03-14 Univ Leuven Kath Modified epitopes for boosting CD4+ T-cell responses
GB201309469D0 (en) 2013-05-28 2013-07-10 Imcyse Sa Detection of CD4+ T lymphocytes
WO2014195803A2 (en) * 2013-06-06 2014-12-11 Anergis S.A. Contiguous overlapping peptides for treatment of house dust mites allergy
US10729791B2 (en) 2015-05-18 2020-08-04 Imcyse Sa Animal models for evaluating pharmaceutical compounds
CA2995771A1 (en) 2015-09-25 2017-03-30 Imcyse Sa Improved methods and compounds for eliminating immune responses to therapeutic agents
SG11201808710UA (en) 2016-04-19 2018-11-29 Imcyse Sa Novel immunogenic cd1d binding peptides
CA3044074A1 (en) * 2016-11-16 2018-05-24 Immunomic Therapeutics, Inc. Nucleic acids for treatment of allergies
KR102010436B1 (ko) * 2018-02-28 2019-08-13 을지대학교 산학협력단 신규 알러지 반응 검사용 조성물

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4234569A (en) * 1978-10-04 1980-11-18 The Johns Hopkins University Production of aldehyde-treated allergen-containing substances
EP0362290A4 (en) * 1987-06-17 1991-09-25 Princess Margaret Children's Medical Research Foundation (Inc.) Cloning of mite allergens
FR2650181B1 (fr) * 1989-07-27 1993-12-03 Laboratoire Stallergenes Procede pour combiner un melange de substances heterogenes a des liposomes
EP0500785B1 (en) * 1989-11-03 2002-04-17 Immulogic Pharmaceutical Corporation A human t cell reactive feline protein (trfp) isolated from house dust and uses therefor
JP2596466B2 (ja) * 1990-03-03 1997-04-02 アサヒビール株式会社 ダニの主要アレルゲンの還伝情報を有するｄｎａおよび該アレルゲンの製造方法
EP0548200B1 (en) * 1990-09-11 1999-04-14 Institute For Child Health Research Cloning and sequencing of allergens of dermatophagoides (house dust mite)

Also Published As

Publication number Publication date
EP0623168B1 (en) 2009-09-30
AU676668B2 (en) 1997-03-20
WO1993008279A1 (en) 1993-04-29
FI941757A0 (fi) 1994-04-15
MX9205985A (es) 1993-08-01
NO941371L (no) 1994-06-15
HU220462B1 (hu) 2002-02-28
DE69233772D1 (de) 2009-11-12
FI941757A (fi) 1994-06-16
IL103452A (en) 2004-07-25
KR940702936A (ko) 1994-09-17
EP0623168A1 (en) 1994-11-09
FI110385B (fi) 2003-01-15
HU9401108D0 (en) 1994-08-29
NO941371D0 (no) 1994-04-15
ATE444360T1 (de) 2009-10-15
KR100260342B1 (ko) 2000-07-01
IL103452A0 (en) 1993-03-15
PT100979B (pt) 1999-08-31
JP2009005709A (ja) 2009-01-15
ES2334179T3 (es) 2010-03-05
HUT71211A (en) 1995-11-28
NO314586B1 (no) 2003-04-14
NZ244772A (en) 1995-09-26
JPH07502890A (ja) 1995-03-30
AU2865492A (en) 1993-05-21

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19930701

FG3A Patent granted, date of granting

Effective date: 19990506

PC4A Transfer of assignment

Owner name: HESKA CORPORATION, US

Effective date: 20061205

TE4A Change of address (patent)

Owner name: HESKA CORPORATION, US

Effective date: 20061207

PC4A Transfer of assignment

Owner name: MERCK PATENT GMBH, DE

Effective date: 20070703

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: MAXIMUM VALIDITY LIMIT REACHED

Effective date: 20140506