PL94095B1 - - Google Patents

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Publication number
PL94095B1
PL94095B1 PL1974176602A PL17660274A PL94095B1 PL 94095 B1 PL94095 B1 PL 94095B1 PL 1974176602 A PL1974176602 A PL 1974176602A PL 17660274 A PL17660274 A PL 17660274A PL 94095 B1 PL94095 B1 PL 94095B1
Authority
PL
Poland
Prior art keywords
phenyl
formula
hydroxy
propoxy
compounds
Prior art date
Application number
PL1974176602A
Other languages
English (en)
Polish (pl)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of PL94095B1 publication Critical patent/PL94095B1/pl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/38—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by doubly-bound oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL1974176602A 1973-12-20 1974-12-19 PL94095B1 (Direct)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT1066673A AT334385B (de) 1973-12-20 1973-12-20 Verfahren zur herstellung von neuen phenoxypropylaminderivaten und deren salzen

Publications (1)

Publication Number Publication Date
PL94095B1 true PL94095B1 (Direct) 1977-07-30

Family

ID=3623884

Family Applications (1)

Application Number Title Priority Date Filing Date
PL1974176602A PL94095B1 (Direct) 1973-12-20 1974-12-19

Country Status (19)

Country Link
US (1) US4034009A (Direct)
JP (2) JPS5412461B2 (Direct)
AT (1) AT334385B (Direct)
BE (1) BE823411A (Direct)
CA (1) CA1001626A (Direct)
CH (1) CH612417A5 (Direct)
CS (1) CS185669B2 (Direct)
DD (1) DD118421A1 (Direct)
ES (1) ES433145A1 (Direct)
FR (1) FR2255058B1 (Direct)
GB (1) GB1441359A (Direct)
IE (1) IE40310B1 (Direct)
IL (1) IL46259A (Direct)
LU (2) LU71514A1 (Direct)
PL (1) PL94095B1 (Direct)
RO (1) RO69147A (Direct)
SU (1) SU547174A3 (Direct)
YU (1) YU36492B (Direct)
ZA (1) ZA748067B (Direct)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4177280A (en) * 1978-07-03 1979-12-04 Syntex (U.S.A.) Inc. Bicyclo[3.1.0]hexyl-substituted carbonylaminophenoxy cardiovascular agents
JPS5757231U (Direct) * 1980-09-19 1982-04-03
US4470965A (en) * 1982-10-27 1984-09-11 Usv Pharmaceutical Corporation Celiprolol for the treatment of glaucoma
DE3410380A1 (de) * 1984-03-21 1985-10-10 Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München S(-)-celiprolol, dessen pharmazeutisch vertraegliche salze, verfahren zu dessen herstellung, verwendung in der therapie und pharmazeutische zubereitungen
DE3544172A1 (de) * 1985-12-13 1987-06-19 Lentia Gmbh Neue kristalline salze von aryloxy-propanolaminen, verfahren zu ihrer herstellung und ihre verwendung
DE3636209A1 (de) * 1986-10-24 1988-04-28 Lentia Gmbh Verfahren zur herstellung eines bindemittelfreien tablettierfaehigen celiprololhydrochlorid-granulates
RS20050106A (sr) 2002-08-19 2007-11-15 Pfizer Products Inc., Kombinovana terapija hiperproliferativnih bolesti
EA009646B1 (ru) * 2003-05-30 2008-02-28 Рэнбакси Лабораториз Лтд. Замещённые производные пиррола и их применение в качестве ингибиторов hmg-coa
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
WO2007029155A2 (en) * 2005-09-05 2007-03-15 Ranbaxy Laboratories Limited An improved process for preparation of pure celiprolol base
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
JP2009514851A (ja) * 2005-11-08 2009-04-09 ランバクシー ラボラトリーズ リミテッド （３ｒ，５ｒ）−７−［２−（４−フルオロフェニル）−５−イソプロピル−３−フェニル−４−［（４−ヒドロキシメチルフェニルアミノ）カルボニル］−ピロール−１−イル］−３，５−ジヒドロキシ−ヘプタン酸ヘミカルシウム塩の製法
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
TW200744583A (en) * 2006-03-14 2007-12-16 Ranbaxy Lab Ltd Statin stabilizing dosage formulations
TW200811101A (en) * 2006-07-14 2008-03-01 Ranbaxy Lab Ltd Polymorphic forms of an HMG-CoA reductase inhibitor and uses thereof
ES2382009T3 (es) 2006-12-01 2012-06-04 Bristol-Myers Squibb Company Derivados de N-((3-bencil)-2,2-(bis-fenil-)-propan-1-amina como inhibidores de CETP para el tratamiento de aterosclerosis y enfermedades cardiovasculares
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EP2527360B1 (en) 2007-06-04 2015-10-28 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8987262B2 (en) 2007-10-19 2015-03-24 Universite de Bordeaux Use of a beta blocker for the manufacture of a medicament for the treatment of hemangiomas
EP2050441A1 (en) 2007-10-19 2009-04-22 Université Victor Segalen Bordeaux 2 Use of beta blocker for the manufacture of a medicament for the treatment of hemangiomas
EP3239170B1 (en) 2008-06-04 2019-03-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
AU2009270833B2 (en) 2008-07-16 2015-02-19 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
US9708367B2 (en) 2013-03-15 2017-07-18 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase and their uses
HK1220611A1 (zh) 2013-03-15 2017-05-12 Bausch Health Ireland Limited 用於治疗胃肠道病症的组成物
EP2986599A1 (en) 2013-04-17 2016-02-24 Pfizer Inc. N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
CN113388007A (zh) 2013-06-05 2021-09-14 博士医疗爱尔兰有限公司 鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
PH12021551686A1 (en) 2019-01-18 2022-05-16 Astrazeneca Ab Pcsk9 inhibitors and methods of use thereof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1214012A (en) * 1967-12-21 1970-11-25 Allen & Hanburys Ltd Phenylethanolamines
FR8183M (Direct) * 1967-12-22 1970-09-07
US3935259A (en) * 1970-01-08 1976-01-27 Ciba-Geigy Corporation New amines and processes for their manufacture
SE354851B (Direct) * 1970-02-18 1973-03-26 Haessle Ab
NL7115581A (Direct) * 1970-11-13 1972-05-16 Dresden Arzneimittel
GB1396322A (en) * 1971-06-15 1975-06-04 Ici Ltd Alkanolamine derivatives
GB1393675A (en) 1971-06-16 1975-05-07 Ici Ltd Alkanolamine derivatives
SE386892B (sv) * 1972-07-06 1976-08-23 Haessle Ab Forfarande for framstellning av oxaminoforeningar
GB1455116A (en) * 1972-12-15 1976-11-10 Ici Ltd Pharmaceutical compositions
AT330150B (de) * 1973-02-28 1976-06-10 Boehringer Sohn Ingelheim Verfahren zur herstellung von neuen 1-phenoxy-2-hydroxy -3- propargylaminopropanen und von deren saureadditionssalzen
GB1460593A (en) * 1973-06-22 1977-01-06 Ici Ltd Ethanolamine derivatives
FI65987C (fi) * 1973-12-12 1984-08-10 Ici Ltd Foerfarande foer framstaellning av nya terapeutiskt anvaendbara alkanolaminderivat
AT334386B (de) * 1973-12-21 1976-01-10 Chemie Linz Ag Verfahren zur herstellung von neuen phenoxypropylaminderivaten und deren salzen

Also Published As

Publication number Publication date
IL46259A0 (en) 1975-03-13
FR2255058A1 (Direct) 1975-07-18
AT334385B (de) 1976-01-10
IE40310B1 (en) 1979-04-25
FR2255058B1 (Direct) 1978-07-28
ATA1066673A (de) 1976-05-15
SU547174A3 (ru) 1977-02-15
JPS53149947A (en) 1978-12-27
JPS5412461B2 (Direct) 1979-05-23
IL46259A (en) 1978-04-30
GB1441359A (en) 1976-06-30
IE40310L (en) 1975-06-20
ES433145A1 (es) 1976-11-16
YU327774A (en) 1982-02-25
AU7653874A (en) 1976-06-17
LU71514A1 (Direct) 1975-08-20
DD118421A1 (Direct) 1976-03-05
JPS5095246A (Direct) 1975-07-29
CS185669B2 (en) 1978-10-31
CH612417A5 (Direct) 1979-07-31
CA1001626A (en) 1976-12-14
JPS5549071B2 (Direct) 1980-12-10
US4034009A (en) 1977-07-05
LU88296I2 (fr) 1994-05-04
ZA748067B (en) 1976-01-28
YU36492B (en) 1984-02-29
BE823411A (fr) 1975-06-16
RO69147A (ro) 1981-07-30

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