PL3952872T3 - Pochodne karbamoilo-cykloheksanu do leczenia zaburzenia ze spektrum autyzmu - Google Patents

Pochodne karbamoilo-cykloheksanu do leczenia zaburzenia ze spektrum autyzmu

Info

Publication number
PL3952872T3
PL3952872T3 PL20719737.7T PL20719737T PL3952872T3 PL 3952872 T3 PL3952872 T3 PL 3952872T3 PL 20719737 T PL20719737 T PL 20719737T PL 3952872 T3 PL3952872 T3 PL 3952872T3
Authority
PL
Poland
Prior art keywords
autism spectrum
spectrum disorder
cyclohexane derivatives
treating autism
carbamoyl
Prior art date
Application number
PL20719737.7T
Other languages
English (en)
Inventor
Viktor ROMÁN
Nika ADHAM-PARANGI
Willie ROGER EARLEY
Paul PO-JEN YEUNG
Original Assignee
Richter Gedeon Nyrt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Nyrt. filed Critical Richter Gedeon Nyrt.
Publication of PL3952872T3 publication Critical patent/PL3952872T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL20719737.7T 2019-04-10 2020-04-09 Pochodne karbamoilo-cykloheksanu do leczenia zaburzenia ze spektrum autyzmu PL3952872T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HUP1900121A HU231500B1 (hu) 2019-04-10 2019-04-10 Karbamoil-ciklohexán származékok autizmus spektrum betegség kezelésére
PCT/IB2020/053382 WO2020208564A1 (en) 2019-04-10 2020-04-09 Carbamoyl cyclohexane derivatives for treating autism spectrum disorder

Publications (1)

Publication Number Publication Date
PL3952872T3 true PL3952872T3 (pl) 2024-07-22

Family

ID=89992883

Family Applications (1)

Application Number Title Priority Date Filing Date
PL20719737.7T PL3952872T3 (pl) 2019-04-10 2020-04-09 Pochodne karbamoilo-cykloheksanu do leczenia zaburzenia ze spektrum autyzmu

Country Status (27)

Country Link
EP (1) EP3952872B1 (pl)
JP (1) JP2022527386A (pl)
KR (1) KR20210151162A (pl)
CN (1) CN113677345A (pl)
AR (1) AR118634A1 (pl)
AU (1) AU2020271363A1 (pl)
BR (1) BR112021019367A2 (pl)
CL (1) CL2021002632A1 (pl)
DK (1) DK3952872T3 (pl)
EA (1) EA202192717A1 (pl)
ES (1) ES2980780T3 (pl)
FI (1) FI3952872T3 (pl)
GE (1) GEP20237554B (pl)
HR (1) HRP20240772T1 (pl)
HU (2) HU231500B1 (pl)
IL (1) IL287076A (pl)
LT (1) LT3952872T (pl)
MX (1) MX2021012321A (pl)
PL (1) PL3952872T3 (pl)
PT (1) PT3952872T (pl)
RS (1) RS65530B1 (pl)
SG (1) SG11202110421YA (pl)
SI (1) SI3952872T1 (pl)
TW (1) TW202103701A (pl)
UY (1) UY38657A (pl)
WO (1) WO2020208564A1 (pl)
ZA (1) ZA202108429B (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114588162B (zh) * 2022-03-30 2023-10-27 中国人民解放军空军军医大学 拉莫三嗪治疗孤独症触觉异常的应用
US11980603B2 (en) 2022-06-11 2024-05-14 AMS Therapeutics, LLC Method of treating expressive language deficit in autistic humans

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU227534B1 (en) 2003-08-04 2011-08-29 Richter Gedeon Nyrt (thio)carbamoyl-cyclohexane derivatives, process for producing them and pharmaceutical compositions containing them
EA017732B1 (ru) 2007-05-11 2013-02-28 Рихтер Гедеон Нирт. Сольватная и кристаллическая формы гидрохлорида транс-1{4-[2-[4-(2,3-дихлорфенил)пиперазин-1-ил]этил]циклогексил}-3,3-диметилмочевины, способы их получения и их применение в фармацевтических композициях и способах лечения состояний, для которых необходима модуляция дофаминовых рецепторов
HU230748B1 (hu) 2007-05-11 2018-02-28 Richter Gedeon Nyrt Új piperazin só és előállítási eljárása
HUP0700353A2 (en) 2007-05-18 2008-12-29 Richter Gedeon Nyrt Metabolites of (thio)carbamoyl-cyclohexane derivatives
EP2185155B1 (en) * 2007-08-03 2017-10-04 Richter Gedeon Nyrt. Pharmaceutical compositions containing dopamine receptor ligands and methods of treatment using dopamine recptor ligands
PL2317852T3 (pl) 2008-07-16 2015-05-29 Richter Gedeon Nyrt Preparaty farmaceutyczne zawierające ligandy receptora dopaminy
US20110117214A1 (en) 2009-11-16 2011-05-19 Auspex Pharmaceuticals, Inc. Cyclohexyl urea modulators of d2 receptors and/or d3 receptors
EP3079688B1 (en) 2013-12-13 2017-11-22 Pierre Fabre Medicament A chromone derivative as a dopamine d3 receptor antagonist for its use in the treatment of autism spectrum disorder

Also Published As

Publication number Publication date
UY38657A (es) 2020-10-30
WO2020208564A1 (en) 2020-10-15
AR118634A1 (es) 2021-10-20
IL287076A (en) 2021-12-01
ES2980780T3 (es) 2024-10-03
HUE066941T2 (hu) 2024-09-28
EP3952872A1 (en) 2022-02-16
SI3952872T1 (sl) 2024-07-31
TW202103701A (zh) 2021-02-01
SG11202110421YA (en) 2021-10-28
BR112021019367A2 (pt) 2021-12-07
JP2022527386A (ja) 2022-06-01
HRP20240772T1 (hr) 2024-09-13
ZA202108429B (en) 2022-09-28
CN113677345A (zh) 2021-11-19
EP3952872B1 (en) 2024-03-13
RS65530B1 (sr) 2024-06-28
HU231500B1 (hu) 2024-04-28
KR20210151162A (ko) 2021-12-13
FI3952872T3 (fi) 2024-06-12
MX2021012321A (es) 2021-11-12
CL2021002632A1 (es) 2022-05-06
DK3952872T3 (da) 2024-05-27
GEP20237554B (en) 2023-10-25
HUP1900121A1 (hu) 2020-10-28
AU2020271363A1 (en) 2021-11-18
EA202192717A1 (ru) 2022-01-17
LT3952872T (lt) 2024-05-27
PT3952872T (pt) 2024-05-22

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