SG11202110421YA - Carbamoyl cyclohexane derivatives for treating autism spectrum disorder - Google Patents

Carbamoyl cyclohexane derivatives for treating autism spectrum disorder

Info

Publication number
SG11202110421YA
SG11202110421YA SG11202110421YA SG11202110421YA SG11202110421YA SG 11202110421Y A SG11202110421Y A SG 11202110421YA SG 11202110421Y A SG11202110421Y A SG 11202110421YA SG 11202110421Y A SG11202110421Y A SG 11202110421YA SG 11202110421Y A SG11202110421Y A SG 11202110421YA
Authority
SG
Singapore
Prior art keywords
autism spectrum
spectrum disorder
cyclohexane derivatives
treating autism
carbamoyl
Prior art date
Application number
SG11202110421YA
Inventor
Viktor Román
Nika Adham-Parangi
Earley Willie Roger
Yeung Paul Po-Jen
Original Assignee
Richter Gedeon Nyrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Nyrt filed Critical Richter Gedeon Nyrt
Publication of SG11202110421YA publication Critical patent/SG11202110421YA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
SG11202110421YA 2019-04-10 2020-04-09 Carbamoyl cyclohexane derivatives for treating autism spectrum disorder SG11202110421YA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU1900121A HU231500B1 (en) 2019-04-10 2019-04-10 Carbamoyl cyclohexane derivatives for treating autism spectrum disorder
PCT/IB2020/053382 WO2020208564A1 (en) 2019-04-10 2020-04-09 Carbamoyl cyclohexane derivatives for treating autism spectrum disorder

Publications (1)

Publication Number Publication Date
SG11202110421YA true SG11202110421YA (en) 2021-10-28

Family

ID=89992883

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202110421YA SG11202110421YA (en) 2019-04-10 2020-04-09 Carbamoyl cyclohexane derivatives for treating autism spectrum disorder

Country Status (18)

Country Link
EP (1) EP3952872B1 (en)
JP (1) JP2022527386A (en)
KR (1) KR20210151162A (en)
CN (1) CN113677345A (en)
AR (1) AR118634A1 (en)
AU (1) AU2020271363A1 (en)
BR (1) BR112021019367A2 (en)
CL (1) CL2021002632A1 (en)
EA (1) EA202192717A1 (en)
GE (1) GEP20237554B (en)
HU (1) HU231500B1 (en)
IL (1) IL287076A (en)
MX (1) MX2021012321A (en)
SG (1) SG11202110421YA (en)
TW (1) TW202103701A (en)
UY (1) UY38657A (en)
WO (1) WO2020208564A1 (en)
ZA (1) ZA202108429B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114588162B (en) * 2022-03-30 2023-10-27 中国人民解放军空军军医大学 Use of lamotrigine for the treatment of autism haptic abnormalities

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU227534B1 (en) * 2003-08-04 2011-08-29 Richter Gedeon Nyrt (thio)carbamoyl-cyclohexane derivatives, process for producing them and pharmaceutical compositions containing them
HU230748B1 (en) 2007-05-11 2018-02-28 Richter Gedeon Nyrt New piperazine salt and process for its preparation
EP2155200B1 (en) 2007-05-11 2016-12-07 Richter Gedeon Nyrt. Crystalline form of a carbamoyl-cyclohexane derivative
HUP0700353A2 (en) 2007-05-18 2008-12-29 Richter Gedeon Nyrt Metabolites of (thio)carbamoyl-cyclohexane derivatives
DK2185155T3 (en) * 2007-08-03 2018-01-02 Richter Gedeon Nyrt PHARMACEUTICAL COMPOSITIONS WITH DOPAMINE RECEPTOR LIGANDS AND TREATMENT METHODS USING DOPAMINE RECEPTOR LIGANDS
JP5774988B2 (en) 2008-07-16 2015-09-09 リヒター ゲデオン ニルバーノシャン ミーケデーレスベニュタールシャシャーグ Formulation of dopamine receptor ligand
US20110117214A1 (en) 2009-11-16 2011-05-19 Auspex Pharmaceuticals, Inc. Cyclohexyl urea modulators of d2 receptors and/or d3 receptors
MX2016007612A (en) 2013-12-13 2016-09-09 Pf Medicament A chromone derivative as a dopamine d3 receptor antagonist for its use for the treatment of autism spectrum disorder.

Also Published As

Publication number Publication date
AU2020271363A1 (en) 2021-11-18
MX2021012321A (en) 2021-11-12
KR20210151162A (en) 2021-12-13
JP2022527386A (en) 2022-06-01
WO2020208564A1 (en) 2020-10-15
EP3952872A1 (en) 2022-02-16
EP3952872B1 (en) 2024-03-13
IL287076A (en) 2021-12-01
UY38657A (en) 2020-10-30
CL2021002632A1 (en) 2022-05-06
BR112021019367A2 (en) 2021-12-07
TW202103701A (en) 2021-02-01
CN113677345A (en) 2021-11-19
HUP1900121A1 (en) 2020-10-28
GEP20237554B (en) 2023-10-25
AR118634A1 (en) 2021-10-20
ZA202108429B (en) 2022-09-28
HU231500B1 (en) 2024-04-28
EA202192717A1 (en) 2022-01-17

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