PT3921026T - Carotenoides c50 para o tratamento ou a prevenção da náusea - Google Patents

Carotenoides c50 para o tratamento ou a prevenção da náusea

Info

Publication number
PT3921026T
PT3921026T PT199143348T PT19914334T PT3921026T PT 3921026 T PT3921026 T PT 3921026T PT 199143348 T PT199143348 T PT 199143348T PT 19914334 T PT19914334 T PT 19914334T PT 3921026 T PT3921026 T PT 3921026T
Authority
PT
Portugal
Prior art keywords
carotenoids
treating
preventing nausea
nausea
preventing
Prior art date
Application number
PT199143348T
Other languages
English (en)
Original Assignee
Massachusetts Gen Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Gen Hospital filed Critical Massachusetts Gen Hospital
Publication of PT3921026T publication Critical patent/PT3921026T/pt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/01Hydrocarbons
    • A61K31/015Hydrocarbons carbocyclic
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11Medicinal preparations comprising living procariotic cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PT199143348T 2019-02-07 2019-05-10 Carotenoides c50 para o tratamento ou a prevenção da náusea PT3921026T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201962802398P 2019-02-07 2019-02-07

Publications (1)

Publication Number Publication Date
PT3921026T true PT3921026T (pt) 2024-03-22

Family

ID=71946373

Family Applications (1)

Application Number Title Priority Date Filing Date
PT199143348T PT3921026T (pt) 2019-02-07 2019-05-10 Carotenoides c50 para o tratamento ou a prevenção da náusea

Country Status (11)

Country Link
US (2) US11001870B2 (pt)
EP (2) EP4331597A3 (pt)
JP (2) JP2022520762A (pt)
KR (1) KR20210125018A (pt)
CN (1) CN113660980A (pt)
AU (1) AU2019428070A1 (pt)
CA (1) CA3128277A1 (pt)
DK (1) DK3921026T3 (pt)
ES (1) ES2974189T3 (pt)
PT (1) PT3921026T (pt)
WO (1) WO2020162959A1 (pt)

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2229288T3 (es) 1995-12-22 2005-04-16 Dsm Ip Assets B.V. Metodos mejorados para transformar cepas de phaffia, cepas de phaffia transformadas asi obtenidas y dna recombinante en dichos metodos.
US6197329B1 (en) * 1999-05-03 2001-03-06 Drugtech Corporation Anti-nausea compositions and methods
CA2386540A1 (en) 1999-10-04 2001-04-12 University Of Medicine And Dentistry Of New Jersey Novel carbamates and ureas
WO2002041833A2 (en) 2000-11-22 2002-05-30 Cargill Incorporated Carotenoid biosynthesis
CA2615419A1 (en) * 2005-07-18 2007-01-25 Basf Aktiengesellschaft Use of a bacillus meti gene to improve methionine production in microorganisms
GB0524873D0 (en) 2005-12-06 2006-01-11 New Royal Holloway & Bedford Bacterial production of carotenoids
US20100124583A1 (en) * 2008-04-30 2010-05-20 Xyleco, Inc. Processing biomass
TW200934872A (en) 2008-02-05 2009-08-16 Echem Hightech Co Ltd A strain of genetically reengineered escherichia coli for biosynthesis of high yield carotenoids after mutation screening
US20090263514A1 (en) * 2008-04-21 2009-10-22 Govindan Gopinathan Cold and flu tonic
US8637263B1 (en) 2010-10-14 2014-01-28 Epiomed Therapeutics, Inc. Assay for determination of compounds having anti-emetic activity
US9562220B2 (en) 2011-06-10 2017-02-07 National University Corporation Chiba University Method for producing carotenoids each having 50 carbon atoms
US10682385B2 (en) 2014-01-10 2020-06-16 Aftab Ahmad Saffron treatment method for mammalian maladies
ES2758179T3 (es) * 2014-05-21 2020-05-04 Nestle Sa Procedimiento para producir una suplementación personalizada de nutrientes
EP3037164A1 (en) 2014-12-23 2016-06-29 Haldor Topsøe A/S Particle separating catalytic chemical reactor and particle separator
US20180296582A1 (en) * 2015-04-23 2018-10-18 Kaleido Biosciences, Inc. Microbiome regulators and related uses thereof
EP3341408A4 (en) * 2015-08-27 2019-04-24 The General Hospital Corporation METHOD AND COMPOSITIONS FOR INHIBITING THE DETOXIFICATION REACTION
WO2017187183A1 (en) 2016-04-27 2017-11-02 Itara Therapeutics Methods for the identification of bifunctional compounds

Also Published As

Publication number Publication date
CA3128277A1 (en) 2020-08-13
EP3921026A4 (en) 2022-10-19
EP3921026A1 (en) 2021-12-15
JP2022520762A (ja) 2022-04-01
US20210230660A1 (en) 2021-07-29
US11001870B2 (en) 2021-05-11
EP4331597A2 (en) 2024-03-06
WO2020162959A1 (en) 2020-08-13
AU2019428070A1 (en) 2021-08-19
EP4331597A3 (en) 2024-05-15
DK3921026T3 (da) 2024-03-18
EP3921026B1 (en) 2023-12-20
ES2974189T3 (es) 2024-06-26
US20200255882A1 (en) 2020-08-13
JP2023110011A (ja) 2023-08-08
KR20210125018A (ko) 2021-10-15
CN113660980A (zh) 2021-11-16

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