PL379625A1 - Nowy sposób syntezy perindoprilu i jego farmaceutycznie dopuszczalnych soli - Google Patents
Nowy sposób syntezy perindoprilu i jego farmaceutycznie dopuszczalnych soliInfo
- Publication number
- PL379625A1 PL379625A1 PL379625A PL37962504A PL379625A1 PL 379625 A1 PL379625 A1 PL 379625A1 PL 379625 A PL379625 A PL 379625A PL 37962504 A PL37962504 A PL 37962504A PL 379625 A1 PL379625 A1 PL 379625A1
- Authority
- PL
- Poland
- Prior art keywords
- perindopril
- synthesis
- pharmaceutically acceptable
- acceptable salts
- novel method
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Indole Compounds (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03291930A EP1367062B1 (fr) | 2003-07-31 | 2003-07-31 | Nouveau procédé de synthèse du perindopril et de ses sels pharmaceutiquement acceptables |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL379625A1 true PL379625A1 (pl) | 2006-10-30 |
| PL211802B1 PL211802B1 (pl) | 2012-06-29 |
Family
ID=29414889
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL379625A PL211802B1 (pl) | 2003-07-31 | 2004-07-29 | Sposób otrzymywania perindoprilu i jego farmaceutycznie dopuszczalnych soli oraz związek przejściowy |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US7368580B2 (pl) |
| EP (1) | EP1367062B1 (pl) |
| JP (1) | JP4263744B2 (pl) |
| CN (1) | CN100439392C (pl) |
| AR (1) | AR045150A1 (pl) |
| AT (1) | ATE338058T1 (pl) |
| AU (1) | AU2004261440B2 (pl) |
| CY (1) | CY1105789T1 (pl) |
| DE (1) | DE60307925T2 (pl) |
| DK (1) | DK1367062T3 (pl) |
| EA (1) | EA008644B1 (pl) |
| ES (1) | ES2271497T3 (pl) |
| HK (1) | HK1096407A1 (pl) |
| MY (1) | MY139098A (pl) |
| NZ (1) | NZ544880A (pl) |
| PL (1) | PL211802B1 (pl) |
| PT (1) | PT1367062E (pl) |
| SI (1) | SI1367062T1 (pl) |
| WO (1) | WO2005012328A2 (pl) |
| ZA (1) | ZA200600480B (pl) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI21800A (sl) * | 2004-05-14 | 2005-12-31 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Nov postopek sinteze perindoprila |
| WO2016178591A2 (en) | 2015-05-05 | 2016-11-10 | Gene Predit, Sa | Genetic markers and treatment of male obesity |
| FR3050380B1 (fr) | 2016-04-20 | 2020-07-10 | Les Laboratoires Servier | Composition pharmaceutique comprenant un betabloquant, un inhibiteur de l'enzyme de conversion et un antihypertenseur ou un ains. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES8604144A1 (es) * | 1984-11-21 | 1986-01-16 | Farmhispania | Procedimiento para la obtencion del acido (2s, 3as, 7as)-1-((s)-1-etoxicarbonil-3-fenilpropil) alanil) exahidro-2-indolincarboxilico |
| FR2807431B1 (fr) * | 2000-04-06 | 2002-07-19 | Adir | Nouveau procede de synthese du perindopril et de ses sels pharmaceutiquement acceptables |
| SI1321471T1 (pl) * | 2003-03-12 | 2005-08-31 | Servier Lab | |
| SI1319668T1 (en) * | 2003-03-12 | 2005-02-28 | Les Laboratoires Servier | Method for synthesis of (2S,3aS,7aS)-1-((S)-alanyl)-octahydro-1H-indole-2-carboxylic acid derivatives and use in the synthesis of perindopril |
-
2003
- 2003-07-31 PT PT03291930T patent/PT1367062E/pt unknown
- 2003-07-31 ES ES03291930T patent/ES2271497T3/es not_active Expired - Lifetime
- 2003-07-31 SI SI200330449T patent/SI1367062T1/sl unknown
- 2003-07-31 DE DE60307925T patent/DE60307925T2/de not_active Expired - Lifetime
- 2003-07-31 AT AT03291930T patent/ATE338058T1/de active
- 2003-07-31 EP EP03291930A patent/EP1367062B1/fr not_active Expired - Lifetime
- 2003-07-31 DK DK03291930T patent/DK1367062T3/da active
-
2004
- 2004-07-29 CN CNB2004800212086A patent/CN100439392C/zh not_active Expired - Fee Related
- 2004-07-29 WO PCT/FR2004/002036 patent/WO2005012328A2/fr active Application Filing
- 2004-07-29 AR ARP040102692A patent/AR045150A1/es not_active Application Discontinuation
- 2004-07-29 EA EA200600249A patent/EA008644B1/ru not_active IP Right Cessation
- 2004-07-29 MY MYPI20043052A patent/MY139098A/en unknown
- 2004-07-29 ZA ZA200600480A patent/ZA200600480B/en unknown
- 2004-07-29 AU AU2004261440A patent/AU2004261440B2/en not_active Ceased
- 2004-07-29 NZ NZ544880A patent/NZ544880A/en not_active IP Right Cessation
- 2004-07-29 JP JP2006521622A patent/JP4263744B2/ja not_active Expired - Fee Related
- 2004-07-29 US US10/566,558 patent/US7368580B2/en not_active Expired - Fee Related
- 2004-07-29 PL PL379625A patent/PL211802B1/pl unknown
-
2006
- 2006-11-16 CY CY20061101671T patent/CY1105789T1/el unknown
-
2007
- 2007-02-01 HK HK07101183.8A patent/HK1096407A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005012328A3 (fr) | 2005-03-24 |
| US20060189813A1 (en) | 2006-08-24 |
| US7368580B2 (en) | 2008-05-06 |
| EA008644B1 (ru) | 2007-06-29 |
| CN1826351A (zh) | 2006-08-30 |
| AU2004261440A1 (en) | 2005-02-10 |
| ATE338058T1 (de) | 2006-09-15 |
| DE60307925D1 (de) | 2006-10-12 |
| HK1096407A1 (en) | 2007-06-01 |
| PL211802B1 (pl) | 2012-06-29 |
| SI1367062T1 (sl) | 2006-12-31 |
| PT1367062E (pt) | 2006-12-29 |
| NZ544880A (en) | 2009-03-31 |
| ZA200600480B (en) | 2007-05-30 |
| CN100439392C (zh) | 2008-12-03 |
| AU2004261440B2 (en) | 2008-07-31 |
| EP1367062B1 (fr) | 2006-08-30 |
| DE60307925T2 (de) | 2007-05-24 |
| EP1367062A1 (fr) | 2003-12-03 |
| WO2005012328A2 (fr) | 2005-02-10 |
| JP4263744B2 (ja) | 2009-05-13 |
| CY1105789T1 (el) | 2011-02-02 |
| MY139098A (en) | 2009-08-28 |
| ES2271497T3 (es) | 2007-04-16 |
| DK1367062T3 (da) | 2007-01-02 |
| JP2006528653A (ja) | 2006-12-21 |
| AR045150A1 (es) | 2005-10-19 |
| EA200600249A1 (ru) | 2006-06-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HK1089187A1 (en) | Novel method for the synthesis of perindopril and the pharmaceutically acceptable salts thereof | |
| AU4847001A (en) | Method for synthesis of perindopril and its pharmaceutically acceptable salts | |
| EG26629A (en) | A new process for the synthesis of pyridopril and its pharmaceutically acceptable salts | |
| AU2001248470A1 (en) | Method for synthesis of perindopril and its pharmaceutically acceptable salts | |
| HK1096409A1 (en) | Novel method for the synthesis of perindopril and the pharmaceutically acceptable salts thereof | |
| HK1089188A1 (en) | Novel method of synthesising perindopril and the pharmaceutically- acceptable salts thereof | |
| EG24152A (en) | Novel method for the synthesis of s-indoline-2-carboxylic acid and application thereof in synthesis of perindopril | |
| HK1096408A1 (en) | Novel method for the synthesis of perindopril and the pharmaceutically acceptable salts thereof | |
| HK1095839A1 (en) | Method for the synthesis of perindopril and the pharmaceutically-acceptable salts thereof | |
| PL1753720T3 (pl) | Proces wytwarzania peryndoprylu i jego soli | |
| SI1371659T1 (sl) | Nov postopek za sintezo perindoprila in njegovih farmacevtsko sprejemljivih soli | |
| HK1086281A1 (en) | Novel method for synthesising perindopril and the pharmaceutically acceptable salt thereof | |
| HK1096407A1 (en) | Novel method for the synthesis of perindopril and the pharmaceutically acceptable salts thereof | |
| HK1096406A1 (en) | Novel method for the synthesis of perindopril and the pharmaceutically acceptable salts thereof | |
| SI1422236T1 (sl) | Postopek za sintezo perindoprila in njegovih farmacevtsko sprejemljivih soli | |
| SI1268424T1 (sl) | Postopek za sintezo perindoprila in njegovih farmacevtsko sprejemljivih soli |