PL373624A1 - Pochodne kwasu 4-(7-fluorowco-2-chino(ksa)linylooksy)-fenoksy propionowego jako środki przeciwnowotworowe - Google Patents

Pochodne kwasu 4-(7-fluorowco-2-chino(ksa)linylooksy)-fenoksy propionowego jako środki przeciwnowotworowe

Info

Publication number
PL373624A1
PL373624A1 PL03373624A PL37362403A PL373624A1 PL 373624 A1 PL373624 A1 PL 373624A1 PL 03373624 A PL03373624 A PL 03373624A PL 37362403 A PL37362403 A PL 37362403A PL 373624 A1 PL373624 A1 PL 373624A1
Authority
PL
Poland
Prior art keywords
linyloxy
quino
phenoxy
halo
propionic acid
Prior art date
Application number
PL03373624A
Other languages
English (en)
Inventor
Jerome P. Horwitz
Thomas H. Corbett
Eduardo Palomino
Lisa Polin
Stuart T. Hazeldine
Original Assignee
Wayne State University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wayne State University filed Critical Wayne State University
Publication of PL373624A1 publication Critical patent/PL373624A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL03373624A 2002-07-03 2003-07-03 Pochodne kwasu 4-(7-fluorowco-2-chino(ksa)linylooksy)-fenoksy propionowego jako środki przeciwnowotworowe PL373624A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US39385802P 2002-07-03 2002-07-03

Publications (1)

Publication Number Publication Date
PL373624A1 true PL373624A1 (pl) 2005-09-05

Family

ID=30115656

Family Applications (1)

Application Number Title Priority Date Filing Date
PL03373624A PL373624A1 (pl) 2002-07-03 2003-07-03 Pochodne kwasu 4-(7-fluorowco-2-chino(ksa)linylooksy)-fenoksy propionowego jako środki przeciwnowotworowe

Country Status (18)

Country Link
US (3) US7109341B2 (pl)
EP (1) EP1539699A1 (pl)
JP (1) JP2005532397A (pl)
CN (1) CN1688547A (pl)
AU (2) AU2003249704B2 (pl)
BR (1) BR0311491A (pl)
CA (1) CA2491612C (pl)
EA (1) EA009679B1 (pl)
GE (1) GEP20074058B (pl)
IL (1) IL164555A0 (pl)
MX (1) MXPA05000233A (pl)
NO (1) NO20050573L (pl)
NZ (1) NZ535887A (pl)
PL (1) PL373624A1 (pl)
SG (1) SG145570A1 (pl)
UA (1) UA79293C2 (pl)
WO (2) WO2004005260A1 (pl)
ZA (1) ZA200408191B (pl)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1412332T3 (da) * 2001-07-31 2005-05-30 Univ Wayne State Quinolinderivater og anvendelse deraf som antitumormidler
UA79293C2 (en) * 2002-07-03 2007-06-11 Univ Wayne State 4-(7'-halo-2-quino (xa-) linyloxy)phenoxy propionic acid derivatives as antineoplastic agents
RU2322236C2 (ru) * 2002-08-24 2008-04-20 Центарис Гмбх Лекарственное средство для лечения доброкачественных и злокачественных опухолевых заболеваний, содержащее производное дисоразола
CN100427482C (zh) * 2005-08-01 2008-10-22 复旦大学 N,n-二甲胺酰基-2,3-二呋喃基-6-氨基喹噁啉,其制备方法与应用
US8183379B2 (en) * 2005-09-07 2012-05-22 Wayne State University Antitumor agents
US20070054938A1 (en) * 2005-09-07 2007-03-08 Horwitz Jerome P Antitumor agents
US7470788B2 (en) * 2005-09-07 2008-12-30 Wayne State University Antitumor agents
EP1897542A1 (en) * 2006-09-07 2008-03-12 Sanofi-Aventis Aqueous formulation comprising an antitumor agent
JP2010526825A (ja) * 2007-05-10 2010-08-05 エーエムアール テクノロジー インコーポレイテッド アリール置換およびヘテロアリール置換テトラヒドロベンゾ−１，４−ジアゼピンならびにノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを遮断するためのその使用
EP2516396A1 (en) * 2009-12-23 2012-10-31 Wayne State University Therapeutic compounds
CN103127112A (zh) * 2013-02-27 2013-06-05 江苏先声药物研究有限公司 一类喹啉酮衍生物在肿瘤治疗中的应用
CN105085506B (zh) * 2014-05-16 2018-01-19 湖南大学 2‑[4‑(苯并噁唑‑2‑氧基)苯氧基]脂肪酰吡啶胺的医药用途
CN105085480B (zh) * 2014-05-16 2017-12-29 湖南大学 2‑[4‑（喹喔啉‑2‑氧基）苯氧基]脂肪酰吡啶胺的医药用途
CN107827828B (zh) * 2017-11-21 2021-03-30 南京华漫新材料科技有限公司 含苯酰肼骨架的喹喔啉衍生物及其制备方法和在制备抗肿瘤药物中的应用
CN110698418B (zh) * 2019-09-11 2022-07-01 广西师范大学 一种3-芳胺基喹喔啉-2-甲酰胺类衍生物及其制备方法和应用
TWI826034B (zh) * 2022-10-07 2023-12-11 宏碁股份有限公司 影像過曝改善方法及電子裝置

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JPS54112628A (en) 1978-02-23 1979-09-03 Canon Inc Electromagnetic driving device
JPS6033389B2 (ja) * 1979-02-22 1985-08-02 日産化学工業株式会社 複素環エ−テル系フェノシキ脂肪酸誘導体、その製造法および該誘導体を含有する除草剤
US6197728B1 (en) * 1980-08-06 2001-03-06 Nissan Chemical Industries Ltd. Quinoxaline derivatives and herbicidal composition
US5364831A (en) * 1980-08-06 1994-11-15 Nissan Chemical Industries Ltd. Quinoxaline derivatives and herbicidal composition
US4760066A (en) * 1982-09-21 1988-07-26 Wayne State University Method for treating human tumor cell metastasis
US4559157A (en) 1983-04-21 1985-12-17 Creative Products Resource Associates, Ltd. Cosmetic applicator useful for skin moisturizing
LU84979A1 (fr) 1983-08-30 1985-04-24 Oreal Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre dont la phase grasse contient un polyether oligomere et polyethers oligomeres nouveaux
PT79699B (en) 1983-12-22 1986-12-10 Pfizer Process for preparing quinolone inotropic agents
US5250690A (en) * 1985-05-02 1993-10-05 Dowelanco Haloalkoxy anilide derivatives of 2-4(-heterocyclic oxyphenoxy)alkanoic or alkenoic acids and their use as herbicides
JPS62190172A (ja) * 1986-02-14 1987-08-20 Teijin Ltd フエノキシ脂肪族カルボン酸誘導体および除草剤
US4820508A (en) 1987-06-23 1989-04-11 Neutrogena Corporation Skin protective composition
US4992478A (en) 1988-04-04 1991-02-12 Warner-Lambert Company Antiinflammatory skin moisturizing composition and method of preparing same
US4938949A (en) 1988-09-12 1990-07-03 University Of New York Treatment of damaged bone marrow and dosage units therefor
WO1994013647A1 (en) * 1992-12-15 1994-06-23 The Du Pont Merck Pharmaceutical Company (2-quinoxalinyloxy)phenoxypropanoic acids and related derivatives as anticancer agents
US6680311B1 (en) * 1996-08-30 2004-01-20 Eli Lilly And Company Cryptophycin compounds
CA2264294A1 (en) * 1996-08-30 1998-03-05 University Of Hawai'i Process for preparing pharmaceutical compounds
JP2001500496A (ja) * 1996-09-06 2001-01-16 イーライ・リリー・アンド・カンパニー 医薬化合物の製造方法
AU4821697A (en) * 1996-10-18 1998-05-15 Wayne State University 6',7'-dihydroxybergamottin, a cytochrome p450 ihnibitor in grapefruit juice
US6352991B1 (en) * 1997-01-08 2002-03-05 Wayne State University 2-hydroxymethylcyclopropylidenemethylpurines and -pyrimidines as antiviral agents
US6238644B1 (en) * 1997-09-03 2001-05-29 Wayne State University Method for treating and/or imaging breast cancer using radioactive iodide
US6586461B1 (en) * 1998-06-16 2003-07-01 Wayne State University Prenyl transferase inhibitors
US6103913A (en) * 1998-10-16 2000-08-15 Eli Lilly And Company Process for preparing enollactone derivatives
WO2001092244A1 (en) * 2000-05-30 2001-12-06 Wayne State University Inhibitors of matrix metalloproteinases
US6747021B2 (en) * 2000-10-02 2004-06-08 Eli Lilly And Company Cryptophycin compound
DK1412332T3 (da) * 2001-07-31 2005-05-30 Univ Wayne State Quinolinderivater og anvendelse deraf som antitumormidler
UA79293C2 (en) 2002-07-03 2007-06-11 Univ Wayne State 4-(7'-halo-2-quino (xa-) linyloxy)phenoxy propionic acid derivatives as antineoplastic agents

Also Published As

Publication number Publication date
US7585863B2 (en) 2009-09-08
WO2004004651A2 (en) 2004-01-15
GEP20074058B (en) 2007-03-12
US7728007B2 (en) 2010-06-01
CN1688547A (zh) 2005-10-26
AU2003249704B2 (en) 2010-05-20
UA79293C2 (en) 2007-06-11
AU2003249704A1 (en) 2004-01-23
US7109341B2 (en) 2006-09-19
SG145570A1 (en) 2008-09-29
EA009679B1 (ru) 2008-02-28
MXPA05000233A (es) 2005-04-11
WO2004005260A1 (en) 2004-01-15
AU2003249722A1 (en) 2004-01-23
US20040132618A1 (en) 2004-07-08
BR0311491A (pt) 2005-04-26
NZ535887A (en) 2006-11-30
US20060293333A1 (en) 2006-12-28
CA2491612A1 (en) 2004-01-15
ZA200408191B (en) 2006-07-26
JP2005532397A (ja) 2005-10-27
NO20050573L (no) 2005-02-02
CA2491612C (en) 2012-01-03
EA200500095A1 (ru) 2005-06-30
IL164555A0 (en) 2005-12-18
US20090076073A1 (en) 2009-03-19
EP1539699A1 (en) 2005-06-15

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Legal Events

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DISC Decisions on discontinuance of the proceedings (taken after the publication of the particulars of the applications)