PL373578A1 - Sposób wytwarzania krystalicznej formy I wodorosiarczanu klopidogrelu - Google Patents

Sposób wytwarzania krystalicznej formy I wodorosiarczanu klopidogrelu

Info

Publication number
PL373578A1
PL373578A1 PL03373578A PL37357803A PL373578A1 PL 373578 A1 PL373578 A1 PL 373578A1 PL 03373578 A PL03373578 A PL 03373578A PL 37357803 A PL37357803 A PL 37357803A PL 373578 A1 PL373578 A1 PL 373578A1
Authority
PL
Poland
Prior art keywords
hydrogen sulphate
crystalline form
clopidogrel hydrogen
clopidogrel
manufacturing crystalline
Prior art date
Application number
PL03373578A
Other languages
English (en)
Inventor
Miroslav Veverka
Stefan Vodny
Eva Veverkova
Josef Hajicek
Hana Stepankova
Original Assignee
Zentiva, A.S.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=31954588&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL373578(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Zentiva, A.S. filed Critical Zentiva, A.S.
Publication of PL373578A1 publication Critical patent/PL373578A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Liquid Crystal Substances (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pyridine Compounds (AREA)
PL03373578A 2002-08-27 2003-08-26 Sposób wytwarzania krystalicznej formy I wodorosiarczanu klopidogrelu PL373578A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CZ20022906A CZ297472B6 (cs) 2002-08-27 2002-08-27 Zpusob výroby clopidogrelu hydrogensulfátu krystalické formy I

Publications (1)

Publication Number Publication Date
PL373578A1 true PL373578A1 (pl) 2005-09-05

Family

ID=31954588

Family Applications (1)

Application Number Title Priority Date Filing Date
PL03373578A PL373578A1 (pl) 2002-08-27 2003-08-26 Sposób wytwarzania krystalicznej formy I wodorosiarczanu klopidogrelu

Country Status (12)

Country Link
US (1) US7714133B2 (pl)
EP (1) EP1554284B1 (pl)
JP (1) JP2006502238A (pl)
KR (1) KR20050058492A (pl)
AT (1) ATE411998T1 (pl)
AU (1) AU2003269673A1 (pl)
CA (1) CA2495823A1 (pl)
CZ (1) CZ297472B6 (pl)
DE (1) DE60324301D1 (pl)
EA (1) EA007977B1 (pl)
PL (1) PL373578A1 (pl)
WO (1) WO2004020443A1 (pl)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0318449A (pt) * 2003-08-04 2006-08-01 Wockhardt Ltd processo para fabricação de (+)-(s)-clopidogrel bissulfato forma-i
DE10337773A1 (de) * 2003-08-13 2005-03-24 Krka Tovarna Zdravil, D.D. Kristallisation von festen Formen von Clopidogrel-Additionssalzen
ES2339944T3 (es) * 2003-11-03 2010-05-27 Cadila Healthcare Limited Procedimientos para preparar la forma i de bisulfato de (s)-(+)-clopidogrel.
RU2328501C1 (ru) * 2004-04-09 2008-07-10 Ханми Фарм. Ко., ЛТД Кристаллический клопидогрель нафталинсульфонат или его гидрат, способ его получения и содержащая его фармацевтическая композиция
EA010198B1 (ru) * 2004-04-19 2008-06-30 Крка, Товарна Здравил, Д.Д., Ново Место Способы получения полиморфной формы i гидросульфата клопидогрела
UA84335C2 (ru) * 2004-04-20 2008-10-10 Санофи Авентис Клопидогрель и его полиморфные формы
AU2005236034A1 (en) * 2004-04-20 2005-11-03 Sanofi-Aventis Polymorphic forms of methyl (+) - (S) -alpha- (2-chlorophenyl) -6, 7-dihydrothieno [3,2-c]pyridine-5(4H) acetate hydrobromide, clopidrogel hydrobromide
EP1693375A1 (en) * 2005-02-21 2006-08-23 KRKA, tovarna zdravil, d.d., Novo mesto Process for preparing clopidrogel hydrogen sulfate of form I
US7772398B2 (en) 2005-03-11 2010-08-10 Dr. Reddy's Laboratories, Inc. Process for making crystalline form I of clopidogrel hydrogen sulphate
WO2007017886A1 (en) * 2005-08-11 2007-02-15 Arch Pharmalabs Limited Novel process for preparation of clopidogrel bisulphate polymorphic form i
EP1926736A4 (en) 2005-09-21 2010-08-25 Chong Kun Dang Pharm Corp NEW RESINATE COMPLEX OF S-CLOPIDOGREL AND METHOD FOR THE PRODUCTION THEREOF
US20080188663A1 (en) * 2007-01-29 2008-08-07 Ashok Kumar Process for the preparation of crystalline clopidogrel hydrogen sulphate Form I
WO2008093357A2 (en) * 2007-01-29 2008-08-07 Ipca Laboratories Limited Process for preparation of crystalline clopidogrel hydrogen sulphate form i
EP3766493B1 (en) 2007-04-27 2023-08-23 CyDex Pharmaceuticals, Inc. Method for improving the stability of clopidogrel using sulfoalkyl ether cyclodextrin
EP2107061A1 (en) 2008-04-02 2009-10-07 Krka Tovarna Zdravil, D.D., Novo Mesto Process for the preparation of optically enriched clopidogrel
US20110118467A1 (en) * 2008-06-24 2011-05-19 Zach System S.P.A. Process for the preparation of clopidogrel hydrogen sulfate crystalline form i
JP5808739B2 (ja) 2009-05-13 2015-11-10 サイデックス・ファーマシューティカルズ・インコーポレイテッド プラスグレル及びシクロデキストリン誘導体を含む医薬組成物並びにその製造方法及び使用方法
WO2011042804A2 (en) * 2009-10-08 2011-04-14 Jubliant Life Sciences Limited An improved process for the preparation of clopidogrel hydrogen sulfate form i
KR101130445B1 (ko) * 2009-10-29 2012-03-27 동아제약주식회사 클로피도그랠 황산수소염 ⅰ형 제조방법
WO2011051976A2 (en) 2009-10-30 2011-05-05 Matrix Laboratories Ltd An improved process for the preparation of clopidogrel bisulfate form i
US20120232274A1 (en) * 2009-11-09 2012-09-13 Pharmazell Gmbh Process for preparation of clopiodogrel bisulfate form-1
WO2011125069A1 (en) 2010-03-22 2011-10-13 Rpg Life Sciences Limited A process for preparation of crystalline form i of clopidogrel bisulfate
CN102558194A (zh) * 2010-12-11 2012-07-11 山东方明药业股份有限公司 一种硫酸氢氯吡格雷i型的制备方法
CN102875568B (zh) * 2012-09-06 2015-12-09 苏州晶云药物科技有限公司 制备(+)-(s)-氯吡格雷硫酸氢盐纯晶型i的方法
KR101710922B1 (ko) 2015-06-03 2017-02-28 경동제약 주식회사 클로피도그렐 황산염 결정형 i형의 제조방법
CN107163060B (zh) * 2017-05-24 2021-03-02 常州制药厂有限公司 一种硫酸氢氯吡格雷晶型ii制备方法
CN107118221B (zh) * 2017-05-24 2021-09-07 常州制药厂有限公司 一种硫酸氢氯吡格雷晶型i制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2623810B2 (fr) 1987-02-17 1992-01-24 Sanofi Sa Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant
FR2779726B1 (fr) * 1998-06-15 2001-05-18 Sanofi Sa Forme polymorphe de l'hydrogenosulfate de clopidogrel
GB0125708D0 (en) * 2001-10-26 2001-12-19 Generics Uk Ltd Novel compounds and processes
US6767913B2 (en) * 2001-12-18 2004-07-27 Teva Pharmaceutical Industries Ltd. Crystal forms iii, iv, v, and novel amorphous form of clopidogrel hydrogensulfate, processes for their preparation, processes for the preparation of form i, compositions containing the new forms and methods of administering the new forms
EP1467735B1 (en) * 2001-12-18 2008-12-10 Teva Pharmaceutical Industries Ltd. Polymorphs of clopidogrel hydrogensulfate
US7074928B2 (en) * 2002-01-11 2006-07-11 Teva Pharmaceutical Industries, Ltd. Polymorphs of clopidogrel hydrogensulfate
JP4072005B2 (ja) * 2002-06-12 2008-04-02 日本電波工業株式会社 温度補償水晶発振器
BR0318449A (pt) * 2003-08-04 2006-08-01 Wockhardt Ltd processo para fabricação de (+)-(s)-clopidogrel bissulfato forma-i

Also Published As

Publication number Publication date
WO2004020443A1 (en) 2004-03-11
US20060041136A1 (en) 2006-02-23
ATE411998T1 (de) 2008-11-15
EP1554284B1 (en) 2008-10-22
EA200500310A1 (ru) 2005-08-25
EP1554284A1 (en) 2005-07-20
JP2006502238A (ja) 2006-01-19
CZ297472B6 (cs) 2006-12-13
CZ20022906A3 (en) 2004-05-12
CA2495823A1 (en) 2004-03-11
KR20050058492A (ko) 2005-06-16
EA007977B1 (ru) 2007-02-27
AU2003269673A1 (en) 2004-03-19
US7714133B2 (en) 2010-05-11
DE60324301D1 (de) 2008-12-04

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