PL369544A1 - Pyridine derivatives as nmda receptor ligands - Google Patents
Pyridine derivatives as nmda receptor ligandsInfo
- Publication number
- PL369544A1 PL369544A1 PL02369544A PL36954402A PL369544A1 PL 369544 A1 PL369544 A1 PL 369544A1 PL 02369544 A PL02369544 A PL 02369544A PL 36954402 A PL36954402 A PL 36954402A PL 369544 A1 PL369544 A1 PL 369544A1
- Authority
- PL
- Poland
- Prior art keywords
- nmda receptor
- receptor ligands
- pyridine derivatives
- pyridine
- derivatives
- Prior art date
Links
- 102000004868 N-Methyl-D-Aspartate Receptors Human genes 0.000 title 1
- 108090001041 N-Methyl-D-Aspartate Receptors Proteins 0.000 title 1
- 239000003446 ligand Substances 0.000 title 1
- 150000003222 pyridines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01126467 | 2001-11-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL369544A1 true PL369544A1 (en) | 2005-05-02 |
Family
ID=8179179
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL02369544A PL369544A1 (en) | 2001-11-09 | 2002-11-02 | Pyridine derivatives as nmda receptor ligands |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6831087B2 (https=) |
| EP (1) | EP1448547B1 (https=) |
| JP (1) | JP4188837B2 (https=) |
| KR (1) | KR100589995B1 (https=) |
| CN (1) | CN100516061C (https=) |
| AR (1) | AR037221A1 (https=) |
| AT (1) | ATE293619T1 (https=) |
| AU (1) | AU2002351816B8 (https=) |
| BR (1) | BR0213977A (https=) |
| CA (1) | CA2467973C (https=) |
| DE (1) | DE60203820T2 (https=) |
| ES (1) | ES2240829T3 (https=) |
| MX (1) | MXPA04004308A (https=) |
| PL (1) | PL369544A1 (https=) |
| RU (1) | RU2303037C2 (https=) |
| WO (1) | WO2003040128A1 (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007008816A (ja) * | 2003-10-15 | 2007-01-18 | Ube Ind Ltd | 新規イソキノリン誘導体 |
| US20050089559A1 (en) * | 2003-10-23 | 2005-04-28 | Istvan Szelenyi | Combinations of potassium channel openers and sodium channel inhibitors or sodium channel-influencing active compounds for treating pains |
| RU2320654C1 (ru) * | 2006-05-24 | 2008-03-27 | Государственное образовательное учреждение высшего профессионального образования "Пермская государственная фармацевтическая академия Федерального агентства по здравоохранению и социальному развитию" (ГОУ ВПО ПГФА Росздрава) | 2,2-ДИМЕТИЛ-4-(4,6-ДИМЕТИЛ-2-ПИРИДОН-3-ИЛ)-1,2-ДИГИДРО-БЕНЗО[f]ИЗОХИНОЛИНА ГИДРОХЛОРИД, ПРОЯВЛЯЮЩИЙ ПРЯМОЕ АНТИКОАГУЛЯНТНОЕ ДЕЙСТВИЕ |
| US8722929B2 (en) * | 2006-10-10 | 2014-05-13 | Valeant Pharmaceuticals International | N-[2-amino-4-(phenylmethoxy)phenyl] amides and related compounds as potassium channel modulators |
| US8367684B2 (en) * | 2007-06-13 | 2013-02-05 | Valeant Pharmaceuticals International | Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators |
| US8563566B2 (en) * | 2007-08-01 | 2013-10-22 | Valeant Pharmaceuticals International | Naphthyridine derivatives as potassium channel modulators |
| US7786146B2 (en) * | 2007-08-13 | 2010-08-31 | Valeant Pharmaceuticals International | Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators |
| US8450327B2 (en) | 2007-10-18 | 2013-05-28 | Boehringer Ingelheim International Gmbh | CGRP antagonists |
| EP2065381A1 (de) | 2007-10-18 | 2009-06-03 | Boehringer Ingelheim Pharma GmbH & Co. KG | CGRP Antagonisten |
| CA2705405A1 (en) | 2007-11-22 | 2009-05-28 | Boehringer Ingelheim International Gmbh | New compounds |
| JP2011504481A (ja) * | 2007-11-22 | 2011-02-10 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 有機化合物 |
| EP2062889A1 (de) * | 2007-11-22 | 2009-05-27 | Boehringer Ingelheim Pharma GmbH & Co. KG | Verbindungen |
| EA014100B1 (ru) * | 2008-02-21 | 2010-08-30 | Общество С Ограниченной Ответственностью "Валексфарм" | Производные 2,4-диаминопиридина, фармацевтическая композиция, лекарственное средство на их основе для лечения или предупреждения заболеваний и нарушений, вызванных гиперактивацией nmda-рецепторов и/или в качестве стимуляторов когнитивных функций и способ лечения |
| RU2438672C1 (ru) | 2010-04-30 | 2012-01-10 | Общество с ограниченной ответственностью "Клевер Фарм" | Агент, проявляющий свойства активатора когнитивных функций (варианты) |
| WO2025124571A1 (zh) * | 2023-12-14 | 2025-06-19 | 斯莱普泰(上海)生物医药科技有限公司 | Nmda受体拮抗剂及其用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA9610738B (en) | 1995-12-22 | 1997-06-24 | Warner Lambert Co | Subtype selective nmda receptor ligands and the use thereof |
| EP1080074B1 (de) * | 1998-05-25 | 2006-11-08 | Abbott GmbH & Co. KG | Heterocyclische substituierte Amide, deren Herstellung und Verwendung |
| US6440995B1 (en) * | 1999-10-01 | 2002-08-27 | Hoffman-La Roche Inc. | Quinolin-4-yl derivatives |
| DK1088818T3 (da) | 1999-10-01 | 2005-03-14 | Hoffmann La Roche | Quinolin-4-yl-derivater |
| US6339093B1 (en) | 1999-10-08 | 2002-01-15 | Hoffmann-La Roche Inc. | Isoquinoline derivatives |
-
2002
- 2002-10-29 US US10/282,365 patent/US6831087B2/en not_active Expired - Fee Related
- 2002-11-02 AU AU2002351816A patent/AU2002351816B8/en not_active Ceased
- 2002-11-02 ES ES02787541T patent/ES2240829T3/es not_active Expired - Lifetime
- 2002-11-02 WO PCT/EP2002/012240 patent/WO2003040128A1/en not_active Ceased
- 2002-11-02 KR KR1020047007031A patent/KR100589995B1/ko not_active Expired - Fee Related
- 2002-11-02 MX MXPA04004308A patent/MXPA04004308A/es active IP Right Grant
- 2002-11-02 JP JP2003542174A patent/JP4188837B2/ja not_active Expired - Fee Related
- 2002-11-02 PL PL02369544A patent/PL369544A1/xx unknown
- 2002-11-02 AT AT02787541T patent/ATE293619T1/de not_active IP Right Cessation
- 2002-11-02 CA CA002467973A patent/CA2467973C/en not_active Expired - Fee Related
- 2002-11-02 CN CNB028222512A patent/CN100516061C/zh not_active Expired - Fee Related
- 2002-11-02 EP EP02787541A patent/EP1448547B1/en not_active Expired - Lifetime
- 2002-11-02 BR BR0213977-4A patent/BR0213977A/pt not_active IP Right Cessation
- 2002-11-02 DE DE60203820T patent/DE60203820T2/de not_active Expired - Lifetime
- 2002-11-02 RU RU2004117595/04A patent/RU2303037C2/ru not_active IP Right Cessation
- 2002-11-06 AR ARP020104227A patent/AR037221A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1448547A1 (en) | 2004-08-25 |
| BR0213977A (pt) | 2004-08-31 |
| CA2467973C (en) | 2009-09-01 |
| CN1585762A (zh) | 2005-02-23 |
| ES2240829T3 (es) | 2005-10-16 |
| MXPA04004308A (es) | 2004-08-11 |
| CA2467973A1 (en) | 2003-05-15 |
| JP2005513004A (ja) | 2005-05-12 |
| AR037221A1 (es) | 2004-10-27 |
| US6831087B2 (en) | 2004-12-14 |
| EP1448547B1 (en) | 2005-04-20 |
| WO2003040128A1 (en) | 2003-05-15 |
| US20030119870A1 (en) | 2003-06-26 |
| AU2002351816B8 (en) | 2008-04-03 |
| DE60203820D1 (de) | 2005-05-25 |
| RU2004117595A (ru) | 2006-01-10 |
| JP4188837B2 (ja) | 2008-12-03 |
| ATE293619T1 (de) | 2005-05-15 |
| AU2002351816B2 (en) | 2008-03-06 |
| DE60203820T2 (de) | 2006-02-23 |
| KR100589995B1 (ko) | 2006-06-19 |
| CN100516061C (zh) | 2009-07-22 |
| KR20050042252A (ko) | 2005-05-06 |
| RU2303037C2 (ru) | 2007-07-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HUP0400249A3 (en) | Pyridine derivatives as 5-ht receptor ligands and uses thereof | |
| IL161439A0 (en) | Cannabinoid receptor ligands | |
| IL156829A0 (en) | Cannabinoid receptor ligands | |
| IL162242A0 (en) | Azaindolylalkylamine derivatives as5-hydroxytryptamine-6 ligands | |
| SI1416935T1 (sl) | 4-amino-6-fenil-pirolo(2,3-d)pirimidinski derivati | |
| PL373953A1 (en) | 7-amino-benzothiazole derivatives as adenosine receptor ligands | |
| IL160181A0 (en) | N-phenylpyrrole guanidine derivatives as melanocortin receptor ligands | |
| AU2003257172A1 (en) | Cannabinoid receptor ligands | |
| IL160701A0 (en) | 3-substituted-4-pyrimidone derivatives | |
| IL157059A0 (en) | 1-aryl-or 1-alkylsulfonylbenzazole derivatives as 5-hydroxytryptamine-6 ligands | |
| AU2002348503A1 (en) | Quinuclidine-substituted heteroaromatic compounds as ligands at nicotinic acetylcholine receptors | |
| IL161409A0 (en) | Methods for ligand discovery | |
| IL158445A0 (en) | Heterocyclyloxy-, -thioxy-and-aminobenzazole derivatives as 5-hydroxytryptamine-6 ligands | |
| AU2001242744A1 (en) | Diphenylalkylamine derivatives useful as opioid delta receptor ligands | |
| PL369544A1 (en) | Pyridine derivatives as nmda receptor ligands | |
| PL369470A1 (en) | Benzothiazole derivatives as adenosine receptor ligands | |
| HUP0303449A3 (en) | Substituted benzofuran-2-carboxamides derivatives | |
| IL157031A0 (en) | Thyroid receptor ligands | |
| IL158448A0 (en) | Heterocyclylalkoxy- alkylthio-and-alkylaminobenzazole derivatives as 5-hydroxytryptamine-6 ligands | |
| HRP20040672A2 (en) | Triazolo-quinolin derivatives useful as adenosine receptor ligands | |
| HRP20050540A2 (en) | Imidazoquinoline derivatives as adenosine a3 receptor ligands | |
| HUP0401949A3 (en) | 4-imidazolin-2-one derivatives | |
| AU3167402A (en) | Aminotriazolopyridiine derivatives as adenosine receptor ligands | |
| AU2001259051A1 (en) | Piperidyindoles as serotonin receptor ligands | |
| AU2003294449A1 (en) | Cannabinoid receptor ligands |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| DISC | Decisions on discontinuance of the proceedings (taken after the publication of the particulars of the applications) |