PL367544A1 - Monotlenek węgla do poprawy rezultatów transplantacji tkanek i narządów oraz do hamowania apoptozy - Google Patents

Monotlenek węgla do poprawy rezultatów transplantacji tkanek i narządów oraz do hamowania apoptozy

Info

Publication number
PL367544A1
PL367544A1 PL02367544A PL36754402A PL367544A1 PL 367544 A1 PL367544 A1 PL 367544A1 PL 02367544 A PL02367544 A PL 02367544A PL 36754402 A PL36754402 A PL 36754402A PL 367544 A1 PL367544 A1 PL 367544A1
Authority
PL
Poland
Prior art keywords
carbon monoxide
tissue
organ transplants
suppresses apoptosis
improves outcomes
Prior art date
Application number
PL02367544A
Other languages
English (en)
Inventor
Fritz H. Bach
Edda M. Tobiasch
Miguel C. Soares
Leo E. Otterbein
Jeanne GOSE
Original Assignee
Beth Israel Deaconess Medical Center Inc.
Yale University
Jeanne GOSE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27404726&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL367544(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Beth Israel Deaconess Medical Center Inc., Yale University, Jeanne GOSE filed Critical Beth Israel Deaconess Medical Center Inc.
Publication of PL367544A1 publication Critical patent/PL367544A1/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Transplantation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL02367544A 2001-06-21 2002-06-21 Monotlenek węgla do poprawy rezultatów transplantacji tkanek i narządów oraz do hamowania apoptozy PL367544A1 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30028901P 2001-06-21 2001-06-21
US33434001P 2001-11-29 2001-11-29
US33797401P 2001-12-07 2001-12-07

Publications (1)

Publication Number Publication Date
PL367544A1 true PL367544A1 (pl) 2005-02-21

Family

ID=27404726

Family Applications (1)

Application Number Title Priority Date Filing Date
PL02367544A PL367544A1 (pl) 2001-06-21 2002-06-21 Monotlenek węgla do poprawy rezultatów transplantacji tkanek i narządów oraz do hamowania apoptozy

Country Status (25)

Country Link
US (2) US7238469B2 (pl)
EP (2) EP2033514A3 (pl)
JP (1) JP4521183B2 (pl)
KR (1) KR20040032115A (pl)
CN (1) CN100502650C (pl)
AT (1) ATE413883T1 (pl)
AU (2) AU2002318377B2 (pl)
BG (1) BG108492A (pl)
BR (1) BR0210599A (pl)
CA (1) CA2451266A1 (pl)
CY (1) CY1108798T1 (pl)
CZ (1) CZ20033448A3 (pl)
DE (1) DE60229848D1 (pl)
DK (1) DK1404811T3 (pl)
ES (1) ES2316583T3 (pl)
HU (1) HUP0400371A3 (pl)
MX (1) MXPA03012031A (pl)
NO (1) NO20035637L (pl)
NZ (1) NZ562962A (pl)
PL (1) PL367544A1 (pl)
PT (1) PT1404811E (pl)
SG (1) SG147305A1 (pl)
SI (1) SI1404811T1 (pl)
SK (1) SK15942003A3 (pl)
WO (1) WO2003000114A2 (pl)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8128963B2 (en) * 1996-09-27 2012-03-06 The Trustees Of Columbia University In The City Of New York Methods for treating ischemic disorders using carbon monoxide
US7678390B2 (en) * 1999-04-01 2010-03-16 Yale University Carbon monoxide as a biomarker and therapeutic agent
GB0111872D0 (en) * 2001-05-15 2001-07-04 Northwick Park Inst For Medica Therapeutic agents and methods
ATE413883T1 (de) 2001-06-21 2008-11-15 Beth Israel Hospital Kohlenmonoxid verbessert die ergebnisse bei gewebe- und organtransplantationen und unterdrückt apoptose
US7968605B2 (en) * 2002-02-04 2011-06-28 ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda. Methods for treating inflammatory disease by administering aldehydes and derivatives thereof
CA2475209A1 (en) * 2002-02-04 2003-08-14 Alfama - Investigacao E Desenvolvimento De Produtos Farmaceuticos Lda. Use of co-releasing compounds for the manufacture of a medicament for the treatment of inflammatory diseases
US20080026984A1 (en) * 2002-02-04 2008-01-31 Alfama - Investigacao E Desenvolvimento De Productos Farmaceuticos Lda Methods for treating inflammatory disease by administering aldehydes and derivatives thereof
BRPI0307673A2 (pt) 2002-02-13 2016-11-08 Beth Israel Hospital métodos de tratar doença vascular.
JP4588325B2 (ja) * 2002-04-15 2010-12-01 ユニバーシティ オブ ピッツバーグ オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション イレウスの治療方法
AU2003226366A1 (en) 2002-04-15 2003-11-03 Beth Israel Deaconess Medical Center Use of heme oxygenase-1 and products of heme degradation
AU2003223562B2 (en) * 2002-04-15 2009-04-09 University Of Pittsburgh Of The Commonwealth System Of Higher Education Methods of treating necrotizing enterocolitis
DK1505990T3 (da) 2002-05-17 2011-11-21 Univ Yale Fremgangsmåder til behandling af hepatitis
US20040258772A1 (en) * 2002-06-05 2004-12-23 Otterbein Leo E. Methods of treating angiogenesis, tumor growth, and metastasis
EA200500062A1 (ru) * 2002-06-21 2005-06-30 Юниверсити Оф Питтсбург Оф Дзе Коммонвелт Систем Оф Хайер Эдьюкейшн Фармацевтическое применение оксида азота, гемоксигеназы-1 и продуктов деградации гема
CN1719975A (zh) * 2002-11-07 2006-01-11 联邦高等教育系统匹兹堡大学 出血性休克的治疗
GB2395432B (en) * 2002-11-20 2005-09-14 Northwick Park Inst For Medica Therapeutic delivery of carbon monoxide to extracorporeal and isolated organs
WO2005041656A2 (en) * 2003-10-22 2005-05-12 Fred Hutchinson Cancer Research Center Methods, compositions and devices for inducing stasis in tissues and organs
EP1552840A1 (en) * 2004-01-07 2005-07-13 Aga Ab Use of a xenon/carbon monoxide mixture for the protection of cells
AU2006220548B2 (en) 2005-03-07 2011-04-21 Sangart, Inc. Composition and methods for delivering carbon monoxide (CO) and nitric ozide (NO) CO to tissue using heme proteins as carriers
EP1937059A2 (en) 2005-07-27 2008-07-02 University Of North Carolina At Charlotte Composition and method for the restoration and preservation of transplant organs procured from dcd donors
WO2007073225A1 (en) * 2005-12-20 2007-06-28 Alfama - Investigação E Desenvolvimento De Produtos Farmacêuticos Lda. Molybdenum carbonyl complexes for treating rheumatoid arthritis and other inflammatory diseases
WO2007073226A1 (en) * 2005-12-20 2007-06-28 Alfama - Investigação E Desenvolvimento De Produtos Farmacêuticos Lda Method for treating a mammal by administration of a compound having the ability to release co
GB0601394D0 (en) 2006-01-24 2006-03-01 Hemocorm Ltd Therapeutic delivery of carbon monoxide
TWI474824B (zh) 2006-11-07 2015-03-01 Gen Hospital Corp 血管活性氧載劑所引發之血管收縮之減輕
MX2011012467A (es) 2009-05-27 2012-01-31 Ino Therapeutics Llc Dispositivos y metodos para engranar un montaje de valvula indexada y deposito presurizado con un zuncho, y para el accionamiento lineal mediante un montaje de embolo en comunicacion fluida con un dispsoitivo para regular la administracion de farmacos.
JP2011010865A (ja) 2009-06-30 2011-01-20 Ikaria Holdings Inc 肺高血圧の臨床的または超音波心臓検査上の証拠を伴う低酸素性呼吸器不全に罹った満期産およびほぼ満期産の新生児を治療する方法
EP2663193B1 (en) 2011-01-14 2019-05-08 Children's Hospital Los Angeles Solution of carbon monoxide for treatment of disease, including sickle cell disease
US8927750B2 (en) 2011-02-04 2015-01-06 Universitaet Zu Koeln Acyloxy- and phosphoryloxy-butadiene-Fe(CO)3 complexes as enzyme-triggered co-releasing molecules
EP2685815A4 (en) 2011-03-16 2014-09-17 Mayo Foundation METHOD AND MATERIALS FOR EXTENDING THE AVAILABILITY OF RETAINED ERYTHROCYTE AND THROMBOZYTE PREPARATES
WO2012145520A2 (en) 2011-04-19 2012-10-26 Alfama, Inc. Carbon monoxide releasing molecules and uses thereof
JP2014520113A (ja) * 2011-06-10 2014-08-21 ゲノ エルエルシー 一酸化窒素（ｎｏ）の加圧容器
EP2734235B1 (en) 2011-07-21 2017-03-22 Alfama, Inc. Ruthenium carbon monoxide releasing molecules and uses thereof
US9987302B2 (en) 2011-08-09 2018-06-05 Beth Israel Deaconess Medical Center, Inc. Methods of treating DNA damage
US9629358B2 (en) 2013-03-15 2017-04-25 Mallinckrodt Hospital Products IP Limited Administration and monitoring of nitric oxide in ex vivo fluids
ES2981406T3 (es) 2013-03-15 2024-10-08 Mallinckrodt Pharmaceuticals Ireland Ltd Administración y monitorización de óxido nítrico en fluidos ex vivo
TW201618795A (zh) * 2014-04-15 2016-06-01 波泰里斯股份有限公司 用以改良器官功能及延長器官移植物壽命之系統及方法
EP3334484B1 (en) 2015-08-12 2024-12-25 The General Hospital Corporation Compositions that promote hypoxia or the hypoxia response for the treatment and prevention of mitochondrial dysfunction
CN105288599A (zh) * 2015-10-22 2016-02-03 徐州医学院 血红素氧化酶-2在制备抑制器官移植免疫排斥制剂中的应用
KR20240142604A (ko) 2017-08-25 2024-09-30 말린크로트 파마슈티칼스 아일랜드 리미티드 기관 생존력을 개선시키는 방법
EP3524290A1 (en) 2018-02-09 2019-08-14 Julius-Maximilians-Universitaet Wuerzburg Method and system for monitoring carbon monoxide (co) administration to ex-vivo fluids
CN116076484A (zh) * 2022-11-30 2023-05-09 武汉大学 一种修复肾脏损伤的低温携氧机械灌注液及其应用

Family Cites Families (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4053590A (en) 1975-02-27 1977-10-11 Alza Corporation Compositions of matter comprising macromolecular hemoglobin
US4264739A (en) * 1979-01-05 1981-04-28 Merck & Co., Inc. Sparger for cell culture system
JPS5679957A (en) 1979-12-05 1981-06-30 Sogo Seibutsu Igaku Kenkyusho:Kk Erucinia enterocolitica polysaccharide sensitizing blood cell and method of detecting erucinia enterocolitica polysaccharide antibody using this
US5240912A (en) * 1983-05-09 1993-08-31 Todaro George J Transforming growth factor (TGF) peptides
US5084380A (en) 1985-01-29 1992-01-28 Applied Biotechnology Monoclonal antibodies reactive with activated and oncogenic ras p21 proteins
CN85202057U (zh) * 1985-05-31 1986-09-10 南京低压阀门厂 电热丝预热凹槽式燃油系统
US5449665A (en) 1985-09-24 1995-09-12 Item Development Aktiebolag Continuous intravenous infusion of adenosine to human patients undergoing percutaneous transluminal angioplasty
DE3739650C1 (de) * 1987-11-23 1989-05-24 Immuno Ag Fermenter zum Zuechten von Zellkulturen
DE3928144A1 (de) * 1989-08-25 1991-02-28 Hoechst Ag Zyklische pyridin-2,4- und -2,5-dicarbonsaeurediamide, verfahren zu deren herstellung sowie deren verwendung
US5180366A (en) 1990-10-10 1993-01-19 Woods W T Apparatus and method for angioplasty and for preventing re-stenosis
US5792325A (en) 1990-11-15 1998-08-11 Richardson, Jr.; William H. Electric arc material processing system
US5396882A (en) 1992-03-11 1995-03-14 The General Hospital Corporation Generation of nitric oxide from air for medical uses
US5570683A (en) 1990-12-05 1996-11-05 The General Hospital Corporation Methods and devices for treating pulmonary vasoconstriction and asthma
US5293875A (en) 1992-06-16 1994-03-15 Natus Medical Incorporated In-vivo measurement of end-tidal carbon monoxide concentration apparatus and methods
CN1245156C (zh) * 1993-02-22 2006-03-15 美国生物科学有限公司 用于体内传送生物制品的方法及用于该方法的组合物
AU6523194A (en) * 1993-03-26 1994-10-24 Biorelease Technologies, Inc. Compositions including heme-containing proteins and methods relating thereto
US5763431A (en) 1993-08-20 1998-06-09 Jackson; Meyer B. Method for regulating neuropeptide hormone secretion
DE4421433C1 (de) 1994-06-18 1995-06-08 Lohmann Therapie Syst Lts Transdermales therapeutisches System mit Wirkstoffen, die Kohlenmonoxid-Quellen darstellen, Verfahren zu seiner Herstellung und seine Verwendung
US5476764A (en) 1994-09-16 1995-12-19 The Regents Of The University Of California Method using CO for extending the useful shelf-life of refrigerated red blood cells
US6066333A (en) 1994-09-22 2000-05-23 William Harvey Research Limited Pharmaceutical control of inflammation
US5664563A (en) 1994-12-09 1997-09-09 Cardiopulmonary Corporation Pneumatic system
US5914316A (en) 1994-12-16 1999-06-22 Washington University Method of inhibiting intimal hyperplasia
US6063407A (en) 1995-02-16 2000-05-16 The General Hospital Corporation Treatment of vascular thrombosis and restenosis with inhaled nitric oxide
US5712293A (en) 1995-06-07 1998-01-27 Sepracor, Inc. Methods for treating gastro-esophageal reflux disease and other disorders associated with the digestive tract using optically pure (-) norcisapride
FR2735382B1 (fr) * 1995-06-15 1997-07-25 Air Liquide Installation de production de monoxyde de carbone incorporant une unite de separation cryogenique
WO1997002036A1 (en) 1995-06-30 1997-01-23 Zymogenetics, Inc. 4-(2-(n-2-carboxamidoindole)aminoethyl)-benzenesulfonamides or sulfonylureas as pdgf antagonists
DK0914103T3 (da) 1996-04-05 2006-10-23 Gen Hospital Corp Behandling af hæmoglobinopati
US6069132A (en) 1996-08-14 2000-05-30 Revanker; Ganapathi R. Phosphazole compounds
DE59710969D1 (de) 1996-08-27 2003-12-11 Messer Griesheim Gmbh Wasserstoffhaltiges medikament
US6315995B1 (en) 1996-09-27 2001-11-13 The Trustees Of Columbia University In The City Of New York Methods for treating an ischemic disorder and improving stroke outcome
WO1998013058A1 (en) 1996-09-27 1998-04-02 The Trustees Of Columbia University In The City Of New York Methods for treating an ischemic disorder and improving stroke outcome
US8128963B2 (en) * 1996-09-27 2012-03-06 The Trustees Of Columbia University In The City Of New York Methods for treating ischemic disorders using carbon monoxide
US6316403B1 (en) 1996-09-27 2001-11-13 The Trustees Of Columbia University In The City Of New York Methods for treating an ischemic disorder and improving stroke outcome
US5869538A (en) * 1996-11-26 1999-02-09 Research Foundation Of State University Of New York Method for enhancing transport of gases to tissues
FR2757259B1 (fr) * 1996-12-18 1999-03-05 Valeo Thermique Moteur Sa Ailette metallique perfectionnee pour echangeur de chaleur, notamment pour vehicule automobile
US5912019A (en) * 1997-02-07 1999-06-15 Musc Foundation For Research Development Compounds for reducing ischemia/reperfusion injury
TR200101504T2 (tr) 1998-03-16 2002-06-21 Celgene Corporation 2-(2,6-dioksopiperidin-3-il)izoindolin türevleri, bunların hazırlanması ve enflamatuar sitokinlerin inhibitörleri olarak kullanımı.
US6203991B1 (en) 1998-08-21 2001-03-20 The Regents Of The University Of Michigan Inhibition of smooth muscle cell migration by heme oxygenase I
US7678390B2 (en) * 1999-04-01 2010-03-16 Yale University Carbon monoxide as a biomarker and therapeutic agent
US20050250688A1 (en) 1999-04-01 2005-11-10 The Trustees Of Columbia University In The City Of New York Methods for treating an ischemic disorder and improving stroke outcome
US7632803B2 (en) * 1999-10-01 2009-12-15 Dmi Life Sciences, Inc. Metal-binding compounds and uses therefor
US6558825B1 (en) * 2000-05-12 2003-05-06 Reveo, Inc. Fuel containment and recycling system
FR2812197B1 (fr) 2000-07-27 2003-01-03 Air Liquide Sante Int Utilisation de co dans le traitement de l'inflammation des voies aeriennes superieures ou des bronches
FR2816212A1 (fr) 2000-11-03 2002-05-10 Air Liquide Sante Int Utilisation de monoxyde de carbone (co) dans le traitement des inflammations du systeme cardiovasculaire
WO2002080859A2 (en) 2001-03-20 2002-10-17 Glaxo Group Limited Inhalation drug combinations
US20030068387A1 (en) * 2001-03-30 2003-04-10 Roland Buelow Carbon monoxide generating compounds for treatment of vascular, inflammatory and immune disorders
GB0111872D0 (en) * 2001-05-15 2001-07-04 Northwick Park Inst For Medica Therapeutic agents and methods
WO2002096387A1 (en) 2001-05-25 2002-12-05 Medtronic, Inc. Implantable medical device with controllable gaseous agent release system
ATE413883T1 (de) * 2001-06-21 2008-11-15 Beth Israel Hospital Kohlenmonoxid verbessert die ergebnisse bei gewebe- und organtransplantationen und unterdrückt apoptose
CA2475209A1 (en) 2002-02-04 2003-08-14 Alfama - Investigacao E Desenvolvimento De Produtos Farmaceuticos Lda. Use of co-releasing compounds for the manufacture of a medicament for the treatment of inflammatory diseases
BRPI0307673A2 (pt) * 2002-02-13 2016-11-08 Beth Israel Hospital métodos de tratar doença vascular.
JP4588325B2 (ja) * 2002-04-15 2010-12-01 ユニバーシティ オブ ピッツバーグ オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション イレウスの治療方法
AU2003226366A1 (en) * 2002-04-15 2003-11-03 Beth Israel Deaconess Medical Center Use of heme oxygenase-1 and products of heme degradation
AU2003223562B2 (en) * 2002-04-15 2009-04-09 University Of Pittsburgh Of The Commonwealth System Of Higher Education Methods of treating necrotizing enterocolitis
DK1505990T3 (da) * 2002-05-17 2011-11-21 Univ Yale Fremgangsmåder til behandling af hepatitis
US20040258772A1 (en) * 2002-06-05 2004-12-23 Otterbein Leo E. Methods of treating angiogenesis, tumor growth, and metastasis
EA200500062A1 (ru) * 2002-06-21 2005-06-30 Юниверсити Оф Питтсбург Оф Дзе Коммонвелт Систем Оф Хайер Эдьюкейшн Фармацевтическое применение оксида азота, гемоксигеназы-1 и продуктов деградации гема
CN1719975A (zh) * 2002-11-07 2006-01-11 联邦高等教育系统匹兹堡大学 出血性休克的治疗
US20050255178A1 (en) * 2004-02-04 2005-11-17 Bloch Kenneth D Enhancing the effectiveness of an inhaled therapeutic gas

Also Published As

Publication number Publication date
MXPA03012031A (es) 2005-07-01
AU2008221551A1 (en) 2008-10-09
BR0210599A (pt) 2004-07-20
SK15942003A3 (sk) 2004-08-03
CY1108798T1 (el) 2014-04-09
HUP0400371A2 (hu) 2004-08-30
JP2005500875A (ja) 2005-01-13
WO2003000114A2 (en) 2003-01-03
CA2451266A1 (en) 2003-01-03
PT1404811E (pt) 2009-01-22
US20070202083A1 (en) 2007-08-30
CN100502650C (zh) 2009-06-24
DE60229848D1 (de) 2008-12-24
EP2033514A3 (en) 2009-04-29
NO20035637L (no) 2004-02-17
NZ562962A (en) 2009-08-28
JP4521183B2 (ja) 2010-08-11
EP2033514A2 (en) 2009-03-11
WO2003000114A9 (en) 2004-05-21
AU2002318377B2 (en) 2008-06-19
ATE413883T1 (de) 2008-11-15
HUP0400371A3 (en) 2010-06-28
US20030039638A1 (en) 2003-02-27
US7238469B2 (en) 2007-07-03
BG108492A (bg) 2005-02-28
ES2316583T3 (es) 2009-04-16
SG147305A1 (en) 2008-11-28
KR20040032115A (ko) 2004-04-14
HK1067380A1 (en) 2005-04-08
CZ20033448A3 (cs) 2004-05-12
WO2003000114A3 (en) 2003-04-10
SI1404811T1 (sl) 2009-04-30
NO20035637D0 (no) 2003-12-17
EP1404811A2 (en) 2004-04-07
CN1545548A (zh) 2004-11-10
DK1404811T3 (da) 2009-03-02
EP1404811B1 (en) 2008-11-12
EP1404811A4 (en) 2006-08-09

Similar Documents

Publication Publication Date Title
PL367544A1 (pl) Monotlenek węgla do poprawy rezultatów transplantacji tkanek i narządów oraz do hamowania apoptozy
WO2004009767A3 (en) Cell therapy for regeneration
WO2004101758A3 (en) Composition for maintaining organ and cell viability
MXPA02007137A (es) Fuente de tejido hepatico.
WO2003077865A3 (en) Methods and compositions for directing cells to target organs
DK1028737T3 (da) Humane mesenchymale stamceller fra perifert blod
WO2004047747A3 (en) Compositions and methods for cell dedifferentiation and tissue regeneration
WO2004113513A3 (en) Methods and compositions for modulating stem cell growth and differentiation
WO2003012060A3 (en) Cellular compositions which facilitate engraftment of hematopoietic stem cells while minimizing the risk of gvhd
MX2007005200A (es) Plaquetas a partir de celulas germinales.
NO20001509L (no) Dannelse av hematopoetiske celler fra multipotente neurale stam-celler
WO2004096975A3 (en) Apparatus and methods for amplification of blood stem cell numbers
EP1676574A3 (en) Methods for promoting survival of transplanted tissues and cells
WO2007025215A3 (en) Machine perfusion of tissue grafts for transplantation
DK1274464T3 (da) Sammensætninger og fremgangsmåder til regulering af proteinekspression i tarm
WO2002098361A3 (en) T cell induced tissue repair and regeneration
WO2004078022A3 (en) Methods of treating disease by transplantation of developing allogeneic or xenogeneic organs or tissues
WO2001040444A3 (de) Verfahren und zusammensetzungen zur herstellung von zelltransplantaten
WO2003102162A3 (en) Novel tolerogenic dendritic cells and therapeutic uses therefor
IL190289A0 (en) Method for obtaining human smooth muscular cells and uses thereof
WO2003029432A3 (en) Human mesenchymal progenitor cell
IL165425A0 (en) Methods of treating disease by transplantation of developing allogeneic or xenogeneic organs or tissues
DK0652943T3 (da) Hæmatopoietiske, fremmende celler og anvendelse deraf
GB2379446A (en) Cells,culture methods and their uses
AU8478601A (en) Methods for culturing human lung mast cells and uses thereof

Legal Events

Date Code Title Description
DISC Decisions on discontinuance of the proceedings (taken after the publication of the particulars of the applications)