PL3636274T3 - Kompozycje do modulowania aktywności gamma-c-cytokiny - Google Patents

Kompozycje do modulowania aktywności gamma-c-cytokiny

Info

Publication number
PL3636274T3
PL3636274T3 PL19206731.2T PL19206731T PL3636274T3 PL 3636274 T3 PL3636274 T3 PL 3636274T3 PL 19206731 T PL19206731 T PL 19206731T PL 3636274 T3 PL3636274 T3 PL 3636274T3
Authority
PL
Poland
Prior art keywords
compositions
cytokine activity
modulating gamma
modulating
gamma
Prior art date
Application number
PL19206731.2T
Other languages
English (en)
Inventor
Yutaka Tagaya
Nazli Azimi
Original Assignee
Bioniz Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioniz Therapeutics, Inc. filed Critical Bioniz Therapeutics, Inc.
Publication of PL3636274T3 publication Critical patent/PL3636274T3/pl

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    • C—CHEMISTRY; METALLURGY
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    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/642—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a cytokine, e.g. IL2, chemokine, growth factors or interferons being the inactive part of the conjugate
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids

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  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
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  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
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  • Birds (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
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PL19206731.2T 2011-01-18 2012-01-17 Kompozycje do modulowania aktywności gamma-c-cytokiny PL3636274T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161433890P 2011-01-18 2011-01-18
US201161527049P 2011-08-24 2011-08-24

Publications (1)

Publication Number Publication Date
PL3636274T3 true PL3636274T3 (pl) 2025-01-20

Family

ID=46516044

Family Applications (2)

Application Number Title Priority Date Filing Date
PL12736203T PL2665486T3 (pl) 2011-01-18 2012-01-17 Kompozycje do modulowania aktywności gamma-c-cytokiny
PL19206731.2T PL3636274T3 (pl) 2011-01-18 2012-01-17 Kompozycje do modulowania aktywności gamma-c-cytokiny

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Application Number Title Priority Date Filing Date
PL12736203T PL2665486T3 (pl) 2011-01-18 2012-01-17 Kompozycje do modulowania aktywności gamma-c-cytokiny

Country Status (19)

Country Link
US (10) US9133244B2 (pl)
EP (3) EP4461742A3 (pl)
JP (4) JP6395379B2 (pl)
CN (2) CN103501805B (pl)
AU (3) AU2012207456C1 (pl)
BR (1) BR112013018046B1 (pl)
CA (1) CA2824515C (pl)
CY (1) CY1122846T1 (pl)
DK (2) DK3636274T3 (pl)
ES (2) ES2778053T3 (pl)
FI (1) FI3636274T3 (pl)
HR (1) HRP20200470T1 (pl)
LT (1) LT2665486T (pl)
PL (2) PL2665486T3 (pl)
PT (2) PT3636274T (pl)
RS (1) RS60050B1 (pl)
SI (1) SI2665486T1 (pl)
SM (1) SMT202000142T1 (pl)
WO (1) WO2012099886A1 (pl)

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WO2015089217A2 (en) 2013-12-10 2015-06-18 Bionz, Llc Methods of developing selective peptide antagonists
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PT3359556T (pt) * 2015-10-09 2021-08-30 Bioniz Llc Modulação da atividade de citocinas gama-c
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CN113874075A (zh) * 2019-05-03 2021-12-31 比奥尼斯有限责任公司 调节γC-细胞因子信号传导对于治疗脱发和脱发相关病症的影响
AU2020291012B2 (en) 2019-06-12 2025-09-25 AskGene Pharma, Inc. Novel IL-15 prodrugs and methods of use thereof
KR102265435B1 (ko) * 2019-08-20 2021-06-15 주식회사 케어젠 피부 미백 활성을 갖는 펩타이드 및 이의 용도
CN115087664A (zh) 2019-11-05 2022-09-20 麦地金公司 IL-2Rβγc结合化合物
CA3160466A1 (en) 2019-11-05 2021-05-14 Medikine, Inc. Dual il-2r and il-7r binding compounds
WO2021158623A1 (en) 2020-02-03 2021-08-12 Medikine, Inc. IL-7Rαγc BINDING COMPOUNDS
CN115297886A (zh) 2020-02-03 2022-11-04 麦地金公司 IL-7Rα结合化合物
JP2023520922A (ja) 2020-04-10 2023-05-22 シートムエックス セラピューティクス，インコーポレイテッド 活性化可能サイトカイン構築物および関連組成物ならびに方法
CN116615221A (zh) * 2020-06-24 2023-08-18 比奥尼斯治疗公司 用于治疗细胞因子释放综合征和细胞因子风暴相关病症的靶向il-2、il-9和il-15信号传导的拮抗肽
US20230321152A1 (en) 2020-09-08 2023-10-12 Dexon Pharmaceuticals Inc. Cytokine storm suppressor, method for using cytokine storm suppressor and screening method
TW202304958A (zh) 2021-03-16 2023-02-01 美商Ｃｙｔｏｍｘ生物製藥公司 經遮蔽之可活化之細胞介素構築體及相關之組成物及方法
JP6974892B1 (ja) 2021-05-27 2021-12-01 デクソンファーマシューティカルズ株式会社 癌悪液質の改善剤および癌悪液質の改善方法
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