IL130238A0 - Conformationally constrained backbone cyclized interleukin-6 antagonists - Google Patents

Conformationally constrained backbone cyclized interleukin-6 antagonists

Info

Publication number
IL130238A0
IL130238A0 IL13023899A IL13023899A IL130238A0 IL 130238 A0 IL130238 A0 IL 130238A0 IL 13023899 A IL13023899 A IL 13023899A IL 13023899 A IL13023899 A IL 13023899A IL 130238 A0 IL130238 A0 IL 130238A0
Authority
IL
Israel
Prior art keywords
interleukin
antagonists
conformationally constrained
backbone cyclized
constrained backbone
Prior art date
Application number
IL13023899A
Original Assignee
Peptor Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Peptor Ltd filed Critical Peptor Ltd
Priority to IL13023899A priority Critical patent/IL130238A0/en
Priority to CA002375657A priority patent/CA2375657A1/en
Priority to NZ515493A priority patent/NZ515493A/en
Priority to PCT/IL2000/000305 priority patent/WO2000072864A1/en
Priority to AU47763/00A priority patent/AU770612B2/en
Priority to JP2000620973A priority patent/JP2003500453A/en
Priority to EP00929763A priority patent/EP1187624A1/en
Publication of IL130238A0 publication Critical patent/IL130238A0/en
Priority to US09/644,456 priority patent/US6841533B1/en
Priority to ZA200109637A priority patent/ZA200109637B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5412—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
IL13023899A 1995-12-07 1999-06-01 Conformationally constrained backbone cyclized interleukin-6 antagonists IL130238A0 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
IL13023899A IL130238A0 (en) 1999-06-01 1999-06-01 Conformationally constrained backbone cyclized interleukin-6 antagonists
CA002375657A CA2375657A1 (en) 1999-06-01 2000-05-28 Conformationally constrained backbone cyclized interleukin-6 antagonists
NZ515493A NZ515493A (en) 1999-06-01 2000-05-28 Conformationally constrained backbone cyclized interleukin-6 antagonists
PCT/IL2000/000305 WO2000072864A1 (en) 1999-06-01 2000-05-28 Conformationally constrained backbone cyclized interleukin-6 antagonists
AU47763/00A AU770612B2 (en) 1999-06-01 2000-05-28 Conformationally constrained backbone cyclized interleukin-6 antagonists
JP2000620973A JP2003500453A (en) 1999-06-01 2000-05-28 Conformationally constrained backbone cyclized interleukin-6 antagonist
EP00929763A EP1187624A1 (en) 1999-06-01 2000-05-28 Conformationally constrained backbone cyclized interleukin-6 antagonists
US09/644,456 US6841533B1 (en) 1995-12-07 2000-08-24 Conformationally constrained backbone cyclized interleukin-6 antagonists
ZA200109637A ZA200109637B (en) 1999-06-01 2001-11-22 Conformationally constrained backbone cyclized interleukin-6 antagonists.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL13023899A IL130238A0 (en) 1999-06-01 1999-06-01 Conformationally constrained backbone cyclized interleukin-6 antagonists

Publications (1)

Publication Number Publication Date
IL130238A0 true IL130238A0 (en) 2000-06-01

Family

ID=11072866

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13023899A IL130238A0 (en) 1995-12-07 1999-06-01 Conformationally constrained backbone cyclized interleukin-6 antagonists

Country Status (8)

Country Link
EP (1) EP1187624A1 (en)
JP (1) JP2003500453A (en)
AU (1) AU770612B2 (en)
CA (1) CA2375657A1 (en)
IL (1) IL130238A0 (en)
NZ (1) NZ515493A (en)
WO (1) WO2000072864A1 (en)
ZA (1) ZA200109637B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6841533B1 (en) 1995-12-07 2005-01-11 Peptor Limited Conformationally constrained backbone cyclized interleukin-6 antagonists
GB2401040A (en) 2003-04-28 2004-11-03 Chugai Pharmaceutical Co Ltd Method for treating interleukin-6 related diseases
JP2005060303A (en) * 2003-08-12 2005-03-10 Sutaagen:Kk Agent for treating or preventing osteoporosis caused by immobility
US9006246B2 (en) * 2010-07-06 2015-04-14 Ono Pharmaceutical Co., Ltd. Tetrahydrocarboline derivative
ES2778053T3 (en) 2011-01-18 2020-08-07 Bioniz Llc Compositions to modulate gamma-c cytokine activity
US9959384B2 (en) 2013-12-10 2018-05-01 Bioniz, Llc Methods of developing selective peptide antagonists
AU2016334085B2 (en) 2015-10-09 2019-11-21 Bioniz Therapeutics, Inc. Modulating gamma - c -cytokine activity

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5210075A (en) * 1990-02-16 1993-05-11 Tanabe Seiyaku Co., Ltd. Interleukin 6 antagonist peptides
JP3525221B2 (en) * 1993-02-17 2004-05-10 味の素株式会社 Immunosuppressants
US5420109A (en) * 1993-11-12 1995-05-30 Houghten Pharmaceuticals, Inc. Cytokine restraining agents
AU3101897A (en) * 1996-06-20 1998-01-07 University Of Sheffield, The Pyridine nucleotide-dependent enzymes

Also Published As

Publication number Publication date
AU770612B2 (en) 2004-02-26
JP2003500453A (en) 2003-01-07
NZ515493A (en) 2003-07-25
WO2000072864A1 (en) 2000-12-07
CA2375657A1 (en) 2000-12-07
ZA200109637B (en) 2002-11-22
EP1187624A1 (en) 2002-03-20
AU4776300A (en) 2000-12-18

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