PL355992A1 - Etanolowy solwat (-)-cis-2-(2-chlorofenylo)-5,7-dihydroksy-8 [4R-(3S-hydroksy-1-metylo) piperydynylo]-4H-1-benzopiran-4-onu - Google Patents

Etanolowy solwat (-)-cis-2-(2-chlorofenylo)-5,7-dihydroksy-8 [4R-(3S-hydroksy-1-metylo) piperydynylo]-4H-1-benzopiran-4-onu

Info

Publication number
PL355992A1
PL355992A1 PL01355992A PL35599201A PL355992A1 PL 355992 A1 PL355992 A1 PL 355992A1 PL 01355992 A PL01355992 A PL 01355992A PL 35599201 A PL35599201 A PL 35599201A PL 355992 A1 PL355992 A1 PL 355992A1
Authority
PL
Poland
Prior art keywords
benzopyran
piperidinyl
chlorophenyl
dihydroxy
cis
Prior art date
Application number
PL01355992A
Other languages
English (en)
Other versions
PL201690B1 (pl
Inventor
Kurt M. Kesseler
Original Assignee
Aventis Pharmaceuticals Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharmaceuticals Inc. filed Critical Aventis Pharmaceuticals Inc.
Publication of PL355992A1 publication Critical patent/PL355992A1/pl
Publication of PL201690B1 publication Critical patent/PL201690B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/453—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
PL355992A 2000-01-18 2001-01-08 Forma II etanolowego solwatu chlorowodorku (-)-cis-2-(2-chlorofenylo)-5,7-dihydroksy-8[4R-(3S-hydroksy-1-metylo)-piperydynylo]-4H-1-benzopiran-4-onu, sposób jej wytwarzania, kompozycja farmaceutyczna i zastosowanie Formy II PL201690B1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US48781500A 2000-01-18 2000-01-18

Publications (2)

Publication Number Publication Date
PL355992A1 true PL355992A1 (pl) 2004-05-31
PL201690B1 PL201690B1 (pl) 2009-04-30

Family

ID=23937213

Family Applications (1)

Application Number Title Priority Date Filing Date
PL355992A PL201690B1 (pl) 2000-01-18 2001-01-08 Forma II etanolowego solwatu chlorowodorku (-)-cis-2-(2-chlorofenylo)-5,7-dihydroksy-8[4R-(3S-hydroksy-1-metylo)-piperydynylo]-4H-1-benzopiran-4-onu, sposób jej wytwarzania, kompozycja farmaceutyczna i zastosowanie Formy II

Country Status (26)

Country Link
EP (1) EP1252155B1 (pl)
JP (1) JP2003520798A (pl)
KR (1) KR100825530B1 (pl)
CN (1) CN1395577A (pl)
AR (1) AR027226A1 (pl)
AT (1) ATE284400T1 (pl)
AU (1) AU2001230869A1 (pl)
BR (1) BR0107724A (pl)
CA (1) CA2397594C (pl)
CZ (1) CZ301235B6 (pl)
DE (1) DE60107652T2 (pl)
DK (1) DK1252155T3 (pl)
EA (1) EA005182B1 (pl)
ES (1) ES2228800T3 (pl)
HU (1) HU225155B1 (pl)
IL (2) IL150643A0 (pl)
MX (1) MXPA02006965A (pl)
NO (1) NO322626B1 (pl)
NZ (1) NZ520281A (pl)
PL (1) PL201690B1 (pl)
PT (1) PT1252155E (pl)
SI (1) SI1252155T1 (pl)
SK (1) SK287216B6 (pl)
TW (1) TWI293072B (pl)
WO (1) WO2001053294A1 (pl)
ZA (1) ZA200205640B (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2769251C2 (ru) 2016-08-23 2022-03-29 Эйсай Ар Энд Ди Менеджмент Ко., Лтд. Комбинированная терапия для лечения гепатоцеллюлярной карциномы
WO2018170447A1 (en) 2017-03-16 2018-09-20 Eisai R&D Management Co., Ltd. Combination therapies for the treatment of breast cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN164232B (pl) * 1986-04-11 1989-02-04 Hoechst India
DE3836676A1 (de) * 1988-10-28 1990-05-03 Hoechst Ag Die verwendung von 4h-1-benzopyran-4-on-derivaten, neue 4h-1-benzopyran-4-on-derivate und diese enthaltende arzneimittel
US5284856A (en) * 1988-10-28 1994-02-08 Hoechst Aktiengesellschaft Oncogene-encoded kinases inhibition using 4-H-1-benzopyran-4-one derivatives
US5908934A (en) * 1996-09-26 1999-06-01 Bristol-Myers Squibb Company Process for the preparation of chiral ketone intermediates useful for the preparation of flavopiridol and analogs

Also Published As

Publication number Publication date
JP2003520798A (ja) 2003-07-08
CA2397594C (en) 2010-03-23
PT1252155E (pt) 2005-04-29
NZ520281A (en) 2004-04-30
KR100825530B1 (ko) 2008-04-25
SK287216B6 (sk) 2010-03-08
CN1395577A (zh) 2003-02-05
IL150643A (en) 2009-08-03
ZA200205640B (en) 2003-11-26
EA200200776A1 (ru) 2002-12-26
HU225155B1 (en) 2006-07-28
IL150643A0 (en) 2003-02-12
BR0107724A (pt) 2002-10-01
WO2001053294A1 (en) 2001-07-26
ES2228800T3 (es) 2005-04-16
EP1252155A1 (en) 2002-10-30
TWI293072B (en) 2008-02-01
DE60107652T2 (de) 2005-12-22
CA2397594A1 (en) 2001-07-26
ATE284400T1 (de) 2004-12-15
PL201690B1 (pl) 2009-04-30
AU2001230869A1 (en) 2001-07-31
DK1252155T3 (da) 2005-04-04
DE60107652D1 (de) 2005-01-13
SK10372002A3 (sk) 2002-12-03
CZ301235B6 (cs) 2009-12-16
SI1252155T1 (en) 2005-06-30
NO322626B1 (no) 2006-11-06
HUP0204297A3 (en) 2005-04-28
EP1252155B1 (en) 2004-12-08
EA005182B1 (ru) 2004-12-30
NO20023385L (no) 2002-08-27
AR027226A1 (es) 2003-03-19
HUP0204297A2 (hu) 2003-04-28
MXPA02006965A (es) 2004-09-06
KR20020069514A (ko) 2002-09-04
NO20023385D0 (no) 2002-07-12
CZ20022467A3 (cs) 2002-10-16

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Legal Events

Date Code Title Description
LAPS Decisions on the lapse of the protection rights

Effective date: 20140108